• 한국공작기계학회논문집
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• 제14권1호
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• pp.81-88
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• 2005

There have been many studies on generation equipment and plant piping, but there is no significant study result on the heat transportation pipe. As such, this study established basic theory on the compensated method among buried pipe for regional heating, and further obtained the following results by applying the conditions of AGFW and NCHPP respectively in calculation of friction and maximum installation distance for the buried pipe. Friction coefficient according to the types and physical properties of soil, friction and maximum installation distance were compared to set the application value of friction coefficient according to the location of works. Calculation formula of clay load to be applied for calculation of friction was introduced to the formula of AGFW and the formula of NCHPP that has been used in Nowon district since 1997 to determine the difference and applicability. $120^{\circ}C$ and $95^{\circ}C$ were applied in temperature difference for expansion volume to compare the arm length at the curve pipe so thai it can be reflected in the design in the future. Maximum installation distance according to thickness of pipe was compared to present the necessity of unified specification so that same kinds of pipe materials can be used for same kinds of works.

• 한국소음진동공학회논문집
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• 제19권11호
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• pp.1151-1157
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• 2009

Ensuring both product quality and reducing material cost are important issue for the design of the piping system of an air conditioner outdoor unit. This paper describes a shape optimization that achieves mass reduction of an air conditioner piping system while satisfying two design constraints on resonance avoidance and the maximum stress in the pipes. In order to obtain optimized design results with various analysis fields considered simultaneously, an automated multidisciplinary analysis system was constructed using PIAnO v.2.4, a commercial process integration and design optimization(PIDO) tool. As the first step of the automated analysis system, a finite element model is automatically generated corresponding to the specified shape of the pipes using a morphing technique included in HyperMesh. Then, the performance indices representing various design requirements (e.g. natural frequency, maximum stress and pipe mass) are obtained from the finite element analyses using appropriate computer-aided engineering(CAE) tools. A sequential approximate optimization(SAO) method was employed to effectively obtain the optimum design. As a result, the pipe mass was reduced by 18 % compared with that of an initial design while all the constraints were satisfied.

• 동의생리병리학회지
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• 제25권3호
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• pp.417-424
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• 2011

Ketoconazole (KET) is an antifungal drug with a broad spectrum of activity that also induces reproductive toxicity in humans and animals. KET inhibits C17-20 lyase which blocks the conversion of 17 ${\alpha}$-hydroxyprogesterone to androstenedione. The effect of Cuscutae semen(CS) extract against KET-induced testicular damage was evaluated in male rats. CS extract was administered orally (100 and 200 mg/kg) for 26 days. Three weeks after CS extract administration, KET was CS-administered intraperitoneally at a dose of 100 mg/kg once a day for 5 days. KET-induced reproductive toxicity was associated with clear reductions of the weights of testes and epididymides, sperm indices and serum testosterone levels. In addition, marked oxidative damage to testicular lipids and alterations of natural antioxidant enzymes were reported in association with KET toxicity. Most of the KET-induced effects were greatly decreased with the concomitant application of CS extract. This study suggests a protective role of Cuscutae semen extract that could be attributed to its antioxidant properties.

• 대한조선학회논문집
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• 제48권4호
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• pp.325-329
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• 2011

Floating, production, storage and offloading (FPSO) is a production facility that refines and saves the drilled crude oil from a drilling facility in the ocean. The flare system in the FPSO is a major part of the pressure relieving system for hydrocarbon processing plants. The flare system consists of a number of pipes and complicated connection systems. Decision of pipe support types is important since the load on the support and the stress in the pipe are influenced by the pipe support type. In this study, we optimally determined the pipe support types that minimized the support cost while satisfying the design constraints on maximum support load, maximum nozzle load and maximum pipe stress ratio. Performance indices included in the design constraints for a specified design were evaluated by pipe structural analysis using CAESAR II. Since pipe support types were all discrete design variables, an evolutionary algorithm (EA) was used as an optimizer. We successfully obtained the optimal solution that reduced the support cost by 27.2% compared to the initial support cost while all the design requirements were satisfied.

• Tuberculosis and Respiratory Diseases
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• 제68권6호
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• pp.334-344
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• 2010

Background: Based on the known immunoregulatory functions of moxifloxacin on phagocytes, the therapeutic effect of moxifloxacin on oleic acid (OA)-induced acute lung injury (ALI) was investigated. Methods: Moxifloxacin (10 mg/kg) was given to male Sprague-Dawley rats that had been given oleic acid (OA, $30{\mu}L$) intravenously. Five hours after OA injection, parameters demonstrating ALI were assessed to measure the effects of moxifloxacin on acute lung injury. Results: The pathological findings of OA-induced ALI's was diminished by moxifloxacin. Through ultrastructural and $CeCl_3$ EM histochemistry, moxifloxacin was confirmed to be effective in decreasing oxidative stress in the lung as well. Indices of ALI, such as lung weight/body weight ratio, protein content in bronchoalveolar lavage fluid, and lung myeloperoxidase were decreased by moxifloxacin. In diaminobenzidine immunohistochemistry, fluorescent immunohistochemistry, and Western blotting of the lung, moxifloxacin had decreased the enhanced expression of secretory phospholipase $A_2$ ($sPLA_2$) by OA. Conclusion: We concluded that moxifloxacin was effective in lessening acute inflammatory pulmonary edema caused by OA, by inhibiting the neutrophilic respiratory burst, which was initiated by the activation of $sPLA_2$.

• 한국농공학회지
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• 제44권6호
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• pp.106-114
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• 2002

In this study, the results of a series of consolidation test for undisturbed Ariake clay in Japan were analyzed by three methods, e-log p (e: void ratio, p: consolidation pressure), log e-log p and n-log p (n: porosity). Moreover, the characteristics of each analysis method were studied. For undisturbed Ariake clay, the log o-Log p and the n-log p relationships can be found as two groups of straight lines of different gradients, but both the elastic consolidation and plastic consolidation regions of e-log p relationship are expressed as a curve. In this paper, the porosity of consolidation yield n$\_$y/, consolidation yield stress p$\_$y/, and the gradient of the plastic consolidation region C$\_$p/ were represented by the log e-log p method, and n$\_$c/, P$\_$cn/ and C$\_$cn/ were represented by the n-log p method. The meaning and the relationships of each value were studied, and the interrelationships among compression indices i.e. C$\_$cn/, C$\_$p/ and C$\_$c/ are obtained from each analysis method as a function of initial porosity n$\_$0/.

• Geomechanics and Engineering
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• 제37권2호
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• pp.149-166
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• 2024

The acoustic emission (AE) technique is utilized to estimate the rock failure status in underground spaces. Understanding the AE characteristics under loading conditions is essential to ensure the reliability of AE monitoring. The AE characteristics depend on the material properties (p-wave velocity, density, UCS, and Young's modulus) and damage stages (stress ratio) of the target rock mass. In this study, two groups of granite specimens (based on the p-wave velocity regime) were prepared to explore the effect of material properties on AE characteristics. Uniaxial compressive loading tests with an AE measurement system were performed to investigate the effect of the rock properties using AE indices (count index, energy index, and amplitude index). The test results were analyzed according to three damage stages classified by the stress ratio of the specimens. Count index was determined to be the most suitable AE index for evaluating rock mass stability.

• 한국사회복지학
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• 제63권2호
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• pp.319-336
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• 2011

본 연구는 외국인 며느리를 둔 시부모를 대상으로 하여 문화적응 스트레스를 측정하기 위한 척도를 개발하고 그 신뢰도와 타당도를 검증해보고자 하였다. 이를 위하여 기존의 유학생을 대상으로 하는 문화적응 스트레스 척도를 기본척도로 하여 다문화 가정의 시부모에 적합하도록 재구성하였다. 분석 결과, 문항의 제거와 표본의 이상치 점검을 위한 문항분석을 통하여 최종적으로 11문항이 선정되었다. 다음으로 문화적응 스트레스 척도의 요인구성을 살펴보기 위하여 탐색적 요인분석을 실시하였으며 시부모의 문화적응 스트레스 척도는 '편견 및 차별감 지각', '문화적 가치관 차이로 인한 갈등', '일상생활의 불편'의 세 가지 요인으로 구성됨을 확인하였다. 이렇게 구성된 척도의 타당도를 검증하기 위하여 구조모형을 통한 확인적 요인분석을 실시하였으며 그 결과 양호한 모형적합도를 보여주었다. 척도의 신뢰도는 Cronbach's ${\alpha}$로 검증하였으며 0.86으로 나타났다.

• 감성과학
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• 제22권1호
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• pp.55-64
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• 2019

스트레스는 자율신경계 반응의 변화를 수반하며, 특히 심박변이도 지표는 스트레스에 의한 자율신경계의 활동을 반영하는 양적 지표로 사용된다. 본 연구에서는 스트레스 완화를 위한 산소와 색채 조명의 복합 자극이 제시되는 동안 자율신경계 반응의 변화를 확인하였다. 42명의 실험참가자는 지난 2주 동안 경험한 스트레스에 대한 증상들을 스트레스 반응 척도에 평가하였다. 스트레스 평가 후, 실험참가자는 복합 자극을 제시받았고, 자극 제시 전과 후, 그리고 자극이 제시되는 동안 심전도 신호가 기록되었다. 자극 조건은 30% 농도의 산소와 백색 조명, 산소와 주황색 조명과 산소와 파란색 조명의 조합의 세 가지로 구성되었다. 심박률(HR), R-R간격의 표준편차(SDNN), 연속한 R-R 간격 차이 값의 평균제곱근(RMSSD)과 심박변이도의 저주파 성분(LF), 고주파 성분(HF), 그리고 LF와 HF의 비율을 심박변이도 지표로 추출하였다. 이들 지표는 자극 제시 전과 후의 평균을 비교하는데 활용되었다. 결과는 자극 조건이 제시되고 난 후, HR과 LF/HF ratio의 유의한 감소를 보여주었다. 특히, 산소와 파란색 조명이 제시된 조건에서 다른 두 조건보다 유의하게 큰 RMSSD와 HF의 증가 및 LF/HF ratio의 감소가 나타났다. 이는 30% 농도의 산소와 파란색 조명의 조건이 부교감신경의 활성화에 의한 자율신경의 균형을 유발하여 스트레스 이완에 가장 효과적임을 보여주었다.

• 대한원격탐사학회지
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• 제38권6_1호
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• pp.1573-1579
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• 2022

기후변화에 따른 우리나라의 빈번한 가뭄에 따라 작물 생산량은 보존하면서 수자원 관리를 극대화하는 방법으로 작물 가뭄스트레스를 조기 탐지하여 적기에 적량이 관수되는 방식이 최근 주목받고 있다. 하지만, 대부분의 선행연구들은 가뭄스트레스가 상당히 진행되어 표징이 뚜렷한 시기에 실험되고 있어 가뭄 스트레스 초기에 원격탐지 될 수 있는 생리적 특징이 많이 알려지지 않았다. 본 연구에서는 콩을 대상으로 초기 수분 스트레스 시기에 열화상 카메라와 초분광 카메라 촬영을 수행하였다. 스트레스 우세 시기 작물 대상의 선행연구들 결과와 마찬가지로 엽온은 높아졌으며, 엽록소 함량을 대표하는 MERIS Terrestrial Chlorophyll Index (MTCI)는 감소하였다. 하지만, 오히려 광합성 능력을 나타내는 Chlorophyll/Carotenoid Index (CCI)가 증가하는 경향이 나타났다. 이는 스트레스 우세 상태와 마찬가지로 가뭄스트레스 초기에도 엽록소와 카로티노이드(carotenoid) 감소가 동시에 일어났지만, 처음의 카로티노이드 감소 속도가 엽록소에 비해 컸기 때문에 일시적으로 엽록소에 대한 카로티노이드 비율이 낮아져서 CCI가 높아진 것으로 사료된다. 이러한 스트레스 초기 반응은 조기탐지 알고리즘 개발에 유용할 것으로 기대한다.