• Journal of Ginseng Research
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• 제46권3호
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• pp.435-443
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• 2022

Background: Post-traumatic stress disorder (PTSD) is a psychiatric disease that develops following exposure to a traumatic event and is a stress-associated mental disorder characterized by an imbalance of neuroinflammation. Korean Red Ginseng (KRG) is the herbal supplement that is known to be involved in a variety of pharmacological activities. We aimed to investigate the effects of KRG on neuroinflammation as a potential mechanism involved in single prolonged stress (SPS) that negatively influences memory formation and consolidation and leads to cognitive and spatial impairment by regulating BDNF signaling, synaptic proteins, and the activation of NF-κB. Methods: We analyzed the cognitive and spatial memory, and inflammatory cytokine levels during the SPS procedure. SPS model rats were injected intraperitoneally with 20, 50, or 100 mg/kg/day KRG for 14 days. Results: KRG administration significantly attenuated the cognitive and spatial memory deficits, as well as the inflammatory reaction in the hippocampus associated with activation of NF-κB in the hippocampus induced by SPS. Moreover, the effects of KRG were equivalent to those exerted by paroxetine. In addition, KRG improved the expression of BDNF mRNA and the synaptic protein PSD-95 in the hippocampus. Taken together, these findings demonstrate that KRG exerts memory-improving actions by regulating anti-inflammatory activities and the NF-κB and neurotrophic pathway. Conclusion: Our findings suggest that KRG is a potential functional ingredient for protecting against memory deficits in mental diseases, such as PTSD.

• JSTS:Journal of Semiconductor Technology and Science
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• 제2권3호
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• pp.164-169
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• 2002

This paper mainly discusses the hard breakdown of 2.2-nm-thick $SiO_2$ films. It is shown that the hard breakdown event of a 2.2-nm-thick $SiO_2$ film greatly depends on the applied electric field. It is strongly suggested that the local weak spots created by applying a low initial stress to a 2.2-nm-thick $SiO_2$film resist the onset of hard breakdown. In other words, it is anticipated that the stored electrostatic energy is fast dissipated by trap-assisted tunneling in 2.2-nm-thick $SiO_2$ film. Consequently, it is strongly suggested that 2.2-nm-thick $SiO_2$ films are intrinsically quite robust.

• 지질공학
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• 제17권1호
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• pp.27-40
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• 2007

한반도 동남부의 제3기 어일분지와 와읍분지를 대상으로 층서를 검토하고, 단층 이동자료 분석을 통하여 분지의 생성 및 진화와 연관이 있는 지구조사건의 과정을 살펴보고자 하였다. 어일분지와 와읍분지는 거의 동시에 각각 별개로 형성되어 제3기 지층들로 충전된 것으로 판단된다. 어일분지와 와읍분지를 충전하고 있는 제3기 지층의 지층단위 분류와 상호관계가 부분적으로 기존 층서와 달라 새롭게 지층명을 첨삭하였다. 어일분지의 장기층군을 하부로부터 감포역암, 홍덕현무암, 노동리역암, 연당현무암으로 분류하였으며, 와읍분지의 범곡리층군을 와읍리응회암, 안동리역암, 용동리응회암, 호암리화산각력암으로 분류하였다. 기반암과 제3기 지층의 11개 지점에서 단층면상 미끄럼선이 발달하는 소단층들의 자료를 수집하여 고응력장을 해석하고, 순서별로 (I) 북서-남동 횡인장, (II) 북서-남동 횡압축 (III)북동-남서 순수 인장, (IV) 남-북 내지 북북동-남남서 횡압축, (V)동-서 내지 동북동-서남서 순수 압축이 작용한 지구조 사건들로 구분하고, 제3기분지 진화와 연관하여 해석하였다. 지구조사건 I은 올리고세 후기 내지 마이오세 초기의 동해 생성과 관련하여 제3기분지의 형성과 발달을 주도하였고, 지구조사건 II, III, IV는 필리핀해판의 섭입경사 및 방향 변화와 관련된 사건으로 본 연구지역에서는 분지 발달의 종료 및 지각 융기를 야기시켰으며, 지구조사건 V는 태평양판의 강한 섭입으로 인한 압축응력이 동해안을 융기시키며 현재까지 지속되고 있는 것으로 해석된다.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1995년도 가을 학술발표회 논문집
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• pp.215-222
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• 1995

The objective of this paper is to develop a finite element structural analysis program using VB(Visual Basic) which has been recently getting popular as development tools of application program for Windows. VB provides several functions to develop an application program easily by supporting event-driven programming method and graphic object as control data type. This system is an integrated processor including preprocessor, solver and postprocessor. Automatic mesh generation is available at preprocess stage, and graphic presentation of deformation and stress is also represented at postprocess one.

• Journal of Yeungnam Medical Science
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• 제39권4호
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• pp.314-321
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• 2022

Background: In this study, the degree of anxiety, depression, and stress caused by coronavirus disease 2019 (COVID-19) was identified, as well as the need for psychological prevention measures among medical students in the Daegu region that was designated the first special disaster area due to the spread of COVID-19. Methods: The subjects of this study were 318 medical students in Daegu who voluntarily participated in an online test using the Hospital Anxiety and Depression Scale and Impact of Event Scale-Revised Korean version. As a result of the test, risk students received immediate telephone counseling, and the effect of this telephone counseling was analyzed. Results: There were no differences in depression, anxiety, or stress according to gender and grade. As a result of immediate telephone counseling for risk students, significant differences were found in depression, anxiety, and stress, and the counseling was found to be effective. Conclusion: For medical students who are easily exposed to stress, the importance of psychological prevention measures and effectiveness of non-face-to-face counseling should be recognized. In the field of medical education, we must do our best to build a system that can be used immediately at the appropriate time for these programs.

• 대한간호학회지
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• 제30권4호
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• pp.956-966
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• 2000

The purpose of this study was to examine the comparative between depression and stress related to life events among women in the menopausal stage. Menopausal stages were divided into two groups: Pre and post-menopausal stages. The degree of depression and stress related to life events between pre and post menopausal women were compared to each other. Women, aged between 41 and 59 years, answered self-reported questionnaires which included Zung's depression scale and life events scale modified by Lee (1984). Findings were as follows; 1) The mean score of premenopausal women who experienced depression was 39.66, and for post-menopausal women the score was 41.45. There was no significant differences in depression levels between pre and post menopausal group.s (t=-1.55, p=.122). 2) Menopausal women experienced low levels of stress related to life events. There were no significant differences between pre and post menopausal groups(t=.527, p>.05). Both pre and post menopausal groups were highly concerned about education issues of their children and disharmony between couples. 3) There was a significant relationship between depression and stress related to life events among post-menopausal groups (r=.22, p<.01). Based on the findings of this study, the menopausal depression was associated with stress related to life events, especially among post-menopausal women. Feelings of lost fertility and feminine attributies result in menopausal depression, which is significantly correlated with women's negative perception of their life events. Therefore, nursing intervention needs to develop to help reduce the levels of depression and overcome their negative perception of the menopausal experience. Nurses should develop nursing strategies to help menopausal women to have positive perceptions and enhance quality of life by assisting their adaptability to physiological and psychological changes related to menopause.

• 대한불안의학회지
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• 제14권2호
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• pp.71-79
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• 2018

Objective : Several earlier studies have reported similar symptoms in patients with posttraumatic stress disorder (PTSD) who have been repeatedly exposed to relevant media after disasters and trauma. This study aimed to examine the effects of indirect trauma experience through media rather than direct traumatic events on an individual's social life. Methods : Five hundred and fifty-four individuals participated in our online, self-reported questionnaire survey. All subjects were asked to complete a demographic questionnaire, Posttraumatic Diagnostic Scale, Beck Depression Inventory, the Impact of Event Scale-Revised, State-Trait Anxiety Inventory, Korean version of Alcohol Use Disorder Identification Test, Patient Health Questionnaire-15, Suicidal Behaviors Questionnaire-Revised. Participants were assessed in regards to their experience of violent media exposure within the past three months. Results : Data from our study indicates that the group exposed to violent media had significantly higher perceived stress, physical symptoms, insomnia, and suicide ideation in comparison to the control group. Among the major symptoms of PTSD, the proportion of intrusion symptoms was relatively high in the media exposed group. Conclusion : This suggests that indirect trauma caused by media exposure could cause post-traumatic stress symptoms. The PTSD caused by indirect trauma may have slight differences from the PTSD caused by direct trauma. Therefore, it is necessary to understand, prevent, and control the adverse effects of media.

• 비교교육연구
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• 제27권1호
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• pp.1-28
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• 2017

본 연구에서는 미국 학교위기대응체계 및 학교기반 위기대응팀과 위기개입을 살펴보고 그 시사점을 도출하여 국내의 학교기반 위기대응체계 구축 및 개선에 방향을 제시하고자 한다. 이를 위해 미국과 한국의 학교기반 위기대응체계에 대한 국내외 문헌을 중심으로 문헌연구를 수행하였다. 미국의 학교기반 위기대응팀의 특징은 다음과 같다. 첫째, 미국은 학교기반 위기대응을 위한 기구와 재정이 법으로 명시되어있어서, 위기발생시 지역, 구, 학교의 역할과 책임소재가 명확하고, 단일한 위기관리 명령체계 구축으로 인한 혼선을 방지한다. 둘째, 학교위기사건 발생 시 학교는 사건지휘체계에 따라 전문위기대응에 관한 역할이 분담되고 위기대응팀과의 협력을 통해 사회 각 영역 간에 의사소통을 원활하게 조정한다. 셋째, 위기대응팀은 위기사건에 지치거나 압도당하지 않도록 팀 구성에 유연성을 발휘하면서 소진을 예방하고 있으며, 학교와 위기대응팀의 협력을 통해 학교자체의 위기역량강화에 초점을 둔다. 넷째, 미국의 학교기반 위기대응팀은 예방단계에서 장기화된 사후관리에 이르기까지 단계별 위기개입을 실시한다. 이러한 결과를 바탕으로 국내 학교기반 위기대응체계의 구축 및 개선에 주는 시사점을 논의하였다.

• 한국지진공학회논문집
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• 제22권6호
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• pp.353-360
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• 2018

This paper is to investigate the micro-behavior of the double-span beams with WUF-W seismic connection under combined axial tension and moment and to propose the rational rotational capacity of it for progressive collapse-resistant analysis and design addressing the stress and strain transfer mechanism. To this end, the behavior of the double-span beams under the column missing event is first investigated using the advanced nonlinear finite element analysis. The characteristics of fracture indices of double-span beams with WUF-W connection under combined axial tension and flexural moment are addressed and then proposed the rational rotational capacity as the basic datum for the progressive collapse-resistant design and analysis. The distribution of fracture indices related to stress and strain for the double-span beams is investigated based on a material and geometric nonlinear finite element analysis. Furthermore, the micro-behavior for earthquake and progressive collapse is explicitly different.

• Journal of Preventive Medicine and Public Health
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• 제35권4호
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• pp.287-294
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• 2002

Objectives : To examine whether cumulative chronic stress influences the immune status, and to verify the effect of social support on the relationship between these two dimensions in male manufacturing workers. Methods : A total of 39 workers were recruited for this study. A structured-questionnaire was used to assess general characteristics, job characteristics (work demand and decision latitude), psychosocial distress, and social support. The serum levels of CD4 and CD8 were measured as immune markers, and were collected between 8:00 and 10:00am in order to standardize the markers. Nonparametric statistics were used to estimate the differences between job characteristics and the immune markers. Results : General characteristics, and health-related behaviors, were not associated with CD4, CD8 or CD4/CD8. No relationships were found between job characteristics and the mean levels of immune reactivity. These results were consistent, even after controlling for social support. Social support failed to modify the relationship toward work demand, decision latitude or psychosocial distress to CD4, CD8, and CD4/CD8. Conclusion : Cumulative chronic life stress might not influence the immune status, and the effects of social support on the immune function under chronic stress, may not play a crucial role in modifying the relationships. This implication supports that the effect of stress on the immune function may be determined by the characteristics of that stress. further research should effectively considers the type, magnitude and timing of a stress event, and modifiable factors, such as personality traits, coping style, and hormone excretion levels, on the alteration of immune status.