• The Korean Journal of Physiology and Pharmacology
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• v.23 no.2
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• pp.95-102
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• 2019

Endoplasmic reticulum (ER) stress is mediated by disturbance of $Ca^{2+}$ homeostasis. The store-operated calcium (SOC) channel is the primary $Ca^{2+}$ channel in non-excitable cells, but its participation in agent-induced ER stress is not clear. In this study, the effects of tunicamycin on $Ca^{2+}$ influx in human umbilical vein endothelial cells (HUVECs) were observed with the fluorescent probe Fluo-4 AM. The effect of tunicamycin on the expression of the unfolded protein response (UPR)-related proteins BiP and CHOP was assayed by western blotting with or without inhibition of Orai1. Tunicamycin induced endothelial dysfunction by activating ER stress. Orai1 expression and the influx of extracellular $Ca^{2+}$ in HUVECs were both upregulated during ER stress. The SOC channel inhibitor SKF96365 reversed tunicamycin-induced endothelial cell dysfunction by inhibiting ER stress. Regulation of tunicamycin-induced ER stress by Orai1 indicates that modification of Orai1 activity may have therapeutic value for conditions with ER stress-induced endothelial dysfunction.

• Journal of the Society of Naval Architects of Korea
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• v.43 no.4 s.148
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• pp.484-493
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• 2006

Recently, direct load analysis using ship motion program is required to confirm structural safety for the Post-Panamax class large container carrier. However, there is no exact comparative study data for structural response between 20 and 30 wave load. So, in this paper, to compare the hull girder stress response between 20 versus 3D wave load calculation method, direct load analysis and global F.E analysis have been performed for three kinds of large container vessels using each 20 and 30 wave load calculation program. The results of 2D wave load RAO(Response Amplitude Operator) of each dominant load parameter(vertical, torsional and horizontal moment) are generally bigger than that of 30 results, especially in vertical wave bending moment. And the results of structural analysis based on the equivalent design wave method shows that there is a big difference in view of stress, but the stress distribution is very similar for each wave load case.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.829-833
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• 2016

Purpose: To investigate the work associated stress and nicotine dependence among law enforcement personnel in Mangalore, India. Materials and Methods: A cross-sectional questionnaire survey was conducted among law enforcement personnel in Mangalore, India. Demographic details, stress factors experienced at work and nicotine dependency were the variables studied. The extent of stress factors experienced at work was assessed using the Effort-Reward Imbalance scale (ERI). Nicotine dependence was measured using the Fagerstrom Test for Nicotine Dependence (FTND) and the Fagerstrom Test for Nicotine Dependence-Smokeless Tobacco (FTND-ST). Logistic regression was used for the statistical analysis. Results: Three hundred and four law enforcement personnel participated in the study, among whom 68 had the presence of one or more habits like tobacco smoking, tobacco chewing and alcohol use. The mean effort score was $15.8{\pm}4.10$ and the mean reward and mean overcommitment scores were $36.4{\pm}7.09$ and $17.8{\pm}5.32$ respectively. Effort/Reward ratio for the total participants was 1.0073 and for those with nicotine habit was 1.0850. Results of our study demonstrated no significant association between domains of ERI scale and presence of habits but work associated stress was associated with the presence of one or more habits. Compared to constables, head constables had 1.12 times higher risk of having a nicotine habit. Conclusions: Our study implies job designation is associated with nicotine habits. However, there was no association between work associated stress and nicotine dependence among law enforcement personnel in Mangalore.

• Journal of the Korean Applied Science and Technology
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• v.34 no.4
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• pp.1036-1045
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• 2017

This study aimed to investigate the relationship between mental health and health risk behaviors of college students and to verify that depression has mediating effects in the relation between perceived stress and health risk behaviors. Data were obtained from the 2015 Community Health Survey conducted nationally, and the subjects of this study were 8,422 college students ranging in age from 19 to 29. Rao-Scott Chi-square test, logistic regression analysis, and Sobel test were used for data analysis. The results of the study showed that perceived stress, depression, present smoking, binge drinking, and high risk drinking of college students were associated with sex, age, and monthly household income. Smoking, binge drinking and high-risk drinking were affected by perceived stress, and depression was an influence factor of current smoking and binge drinking. Depression showed partial mediating effect between perceived stress and current smoking and between perceived stress and binge drinking. Such results suggest that a comprehensive behavioral health intervention strategy that covers mental health care of college students is necessary.

• Korean Journal of Food Science and Technology
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• v.18 no.5
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• pp.364-371
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• 1986

High-ester pectin was demethylated by the treatments of HCl alone and a combination of HCl and $NH_4OH$. The low-ester pectin prepared were analyzed for chemical composition and the pectin gels were evaluated for firmness by sag values and strength by puncture stress. Gels made from HCl demethylated sample showed brittle, weak and poor elastic characteristics while the $HCl-NH_4OH$ treated samples generally resulted in a smooth and elastic gels except those samples having very low content of ester group or acid amide group. Statistical analysis showed that significant correlations were found between sag values and ester content or molecular weight, and puncture stress and ester content, acid amide groups or molecular weight. The equations derived for sag, puncture stress and sag/puncture stress from chemical data could be useful for prediction of some of the physical properties of low-ester pectin gel.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.4
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• pp.509-516
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• 2011

The performance of naked neck and normal chicken was evaluated with respect to growth, carcass, immune, biochemical and stress parameters under winter and summer seasons to assess the suitability of naked neck birds under high temperatures in the global scenario of climate change. The growth performance was significantly ($p{\leq}0.05$) higher in naked neck chicken in the summer season. The dressing percentage was significantly ($p{\leq}0.05$) higher in naked neck birds in both winter and summer season because of reduced plumage. The thigh, giblet and feather proportion significantly ($p{\leq}0.05$) varied between naked neck and normal chickens in summer season. The humeral immune response to sheep red blood cells (SRBC), Newcastle disease vaccine (NDV) and cutaneous basophil hypersensitivity (CBH) did not show any significant differences among the chicken groups. The protein and cholesterol concentration observed was within the normal ranges. The total cholesterol levels in plasma were significantly ($p{\leq}0.05$) lower in naked neck birds in both the seasons. H:L ratio was significantly ($p{\leq}0.05$) lower in summer season indicating less stress in naked neck chicken. Basophil and eosinophil concentration was significantly ($p{\leq}0.05$) higher in normal chicken in summer. The lipid peroxidation was higher in full feathered birds under summer stress. The enzyme glutathione reductase (GR) levels were significantly higher during the summer and varied significantly ($p{\leq}0.05$) between the normal and naked neck chicken in both seasons. The results indicated that the naked neck birds performed significantly better at high ambient temperatures with respect to growth, carcass and biochemical parameters. It was concluded that the ability of the naked neck chicken to adapt to high temperatures foresees a viable option for the biological mitigation of climate change.

• Journal of the Korea Convergence Society
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• v.13 no.5
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• pp.389-400
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• 2022

This study was conducted to identify factors influencing mental health of one-person household members. Using data from the 2019 Korea National Health and Nutrition Examination Survey, 768 subjects were included. The SPSS/Win 21.0 program was used, and the complex sample design data were analyzed by Rao-Scott 𝑥² test and multiple logistic regression analysis. Of the subjects, 29.9% perceived high stress, 16.2% felt depressed, and 8.2% had suicidal ideation. The influencing factors of stress perception were age and subjective health status(p<.001). Factors influencing depressed mood were household income, subjective health status, and perceived stress(p<.001). Factors influencing suicidal ideation were age, household income, subjective health status, perceived stress, and depressed mood(p<.001). The results of this study can be used as basic data for improving mental health services of one-person household members.

• Journal of Convergence for Information Technology
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• v.11 no.1
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• pp.199-207
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• 2021

This study was attempted to understand the effect of the violence victim experience of Korean adolescents on smoking using the data of the 15th (2019) online youth health behavior survey. The subjects of this study were 57,303 people, and the data were analyzed using the SPSS / Win 26.0 program for frequency analysis of complex samples, cross sample analysis (Rao-Scott ��2 test), and logistic regression analysis of complex samples. The main result was 12.7% of the smoking subjects. Those who smoked were significantly more 9.6% and 22.0%, respectively, compared to those who had no more than 1 or 2 times of violence. Smoking of Korean adolescents adjusted for gender, grade, academic record, economic status, drinking, family living, and usual stress increased the odds ratio for smoking by 1.66 times when the degree of violence damage experience increased by 1 unit. As a result of the above, as the degree of violence victimization of adolescents increases, the likelihood of smoking increases. Therefore, it is necessary to multidisciplinary convergence effort to the prevention and management of violence of adolescents, and to reduce the smoking of adolescents.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.2
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• pp.247-252
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• 2013

An experiment was conducted to determine the effect of supplementing various concentrations (0, 100, 200, 300, or 400 ${\mu}g/kg$ diet) of organic Se on growth performance, carcass traits, oxidative stress, and immune responses in commercial broiler chickens reared in open-sided poultry house under tropical climatic conditions. Each diet was fed ad libitum to eight replicates consisting of six birds in each pen from 1 to 42 d of age. Body weight gain and feed efficiency, and relative weight of liver, abdominal fat and ready to cook yields were not affected (p>0.05) by organic Se supplementation to broiler diets. Lipid peroxidation in plasma decreased, while activities of glutathione peroxidase and glutathione reductase in plasma increased (p<0.01) linearly with Se concentration in diet. The ratios between heterophyls and lymphocytes and relative weight of lymphoid organs (bursa, spleen, and thymus), and antibody production to Newcastle disease vaccination were not affected (p>0.05) by Se supplementation to broiler diets. However, the cell-mediated immunity (lymphocyte proliferation ratio) increased (p<0.01) linearly with dietary Se concentration. The results of the present study indicate that the supplementation of Se did not influence body weight and feed efficiency. However, supplementation of Se increased antioxidant status and lymphocyte proliferation in broiler chickens.

• Journal of Korean Public Health Nursing
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• v.28 no.1
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• pp.71-86
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• 2014

Purpose: This study was conducted in order to identify factors that predict suicidal ideation and depression according to gender among Korean adults. Method: From the data base of the fifth Korean National Health and Nutritional Examination Survey(KNHANESV-1, 2010), data on 4,894 adults aged 19~64 were used. Data were analyzed by application of the Rao-Scott Chi-Square test and logistic analysis with SAS 9.2. Results: Overall, 8.5% of men and 18.1% of women had suicidal ideation during the last year; 7.5% of men and 17.0% of women had depression during the last two weeks. Risk factors for suicidal ideation include perceived high stress(OR male 3.649, female 2.941), depression(OR male 10.109, female 6.033), poor cognition of health status(OR male 8.115, female 6.664), low economic status(OR male 1.898), and low educational status(OR female 1.631). Risk factors for depression include perceived high stress(OR male 2.678, female 3.686), suicidal ideation(OR male 9.925, female 6.022), non-employed(OR female 1.525), married(OR female 2.392), and physical discomfort(OR female 1.545). Conclusions: Based on the above mentioned results, risk factors of suicidal ideation and depression differed according to gender. Development of various policies and appropriate intervention programs according to gender, that lessen the risk of suicidal ideation and depression for adults is needed.