• Asian-Australasian Journal of Animal Sciences
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• v.15 no.7
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• pp.1022-1025
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• 2002

Effect of chemical stress of daily administration of glucocorticoid (dexamethasone @0.125 mg./calf/day) injections on plasma zinc levels, Zn status of body tissues and its distribution in sub cellular fractions, was studied in neonatal buffalo calves. Daily i/m injections of dexamethasone, starting at the completion of 1 week of age and continued till 8th week, led to a significant decline in plasma Zn concentration from 3rd week onwards, which then persisted throughout the rest of the experimental period. In control group, liver had the highest concentration of zinc, followed by heart, muscle, spleen, kidney and testis. In all these tissues, cytosolic fractions had the highest (>60%) zinc levels followed by nuclear, mitochondrial and microsomal fractions. In dexamethasone treated calves, there was a significant increase in the Zn uptake by the tissues of liver and muscle. This increase in zinc concentration was observed in all the sub cellular fractions of liver and muscle, however about 80% of this increase was in cytosolic fraction. It was concluded that glucocorticoid-induced stress caused increase in Zn levels of liver/muscles and decrease in blood plasma zinc, thus indicating a redistribution of Zn in body.

• Journal of the Korea Institute of Military Science and Technology
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• v.4 no.1
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• pp.246-254
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• 2001

The breech system can be considered as a pressure vessel with an internal plug under high explosive pressure. The system consists of a breech block(internal plug) whose front surface subjects to pressure, and a breech ring(pressure vessel). There is the geometric discontinuity around roots of connection parts and then stress concentration is introduced due to pressure, where contact effect may be ignored because contact plane between two equipments is parallel ideally, Generally high stress concentration phenomena shorten the life cycle of the mechanical system. It is well known that shock load is much more harmful on safety of the system than static load. In this present paper, several geometric design variables which may affect stress condition on the system are chosen and the parametric study on the design variables is carried using commercial FEM codes. Finally, the obtained results in the single lug breech system are applied to design the 3 lugs breech system. The 3 lugs breech system can reduce the maximum stress level.

• Structural Engineering and Mechanics
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• v.32 no.4
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• pp.549-561
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• 2009

As it is known, laminated composite materials are increasingly used in many technological applications, and in some instance, cutouts must be made into laminated panels for practical reasons, changing the stress distribution. The present study deals with the determination of the stress concentration factor that holes of square shape cause in an orthotropic plate subjected to distributed in - plane loading. Square holes of rounded corners in a rectangular plate are considered, and the effect of different combinations of axial and tangential forces applied to its middle plane at the external edges, is studied. The mutually perpendicular axes, which define the principal axes of orthotropy, are assumed in many different directions referred to the sides of the plate. Numerical experiments by means of a finite element code is performed, evaluating the influence of the fiber orientation with respect to the edges of the plate and the characteristics of the orthotropic materials since such structures do not exhibit easily predictable behavior.

• Journal of Korean Society on Water Environment
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• v.28 no.2
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• pp.213-218
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• 2012

Abnormal dissolved oxygen concentration in aquatic habitat, both depletion and supersaturation, can be stress factor to aquatic animals. In this study the nationwide distribution of oxygen supersaturation was analyzed for three categories of streams (43 urban streams, 15 rural streams, and 14 forest streams) by using monitoring network data of the Korean Ministry of Environment. From the distribution analysis 30% of urban streams showed hyperoxic condition of eutrophic level, while no forest stream showed hyperoxic condition. The physiological effect of hyperoxia on fish was examined using two species of fish Zacco koreanus, which resulted in higher concentration of a stress hormone (cortisol) in fish exposed to hyperoxic concentration (196%) of oxygen. This study shows that hyperoxic condition is ubiquitous in urban and rural Korean streams, and it can be a stress factor to aquatic animals.

• Biomolecules & Therapeutics
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• v.30 no.6
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• pp.570-575
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• 2022

Stress breaks body balance, which can cause diverse physiological disorders and worsen preexisting diseases. However, recent studies have reported that controllable stress and overcoming from stress reinforce resilience to resist against more intense stress afterwards. In this study, we investigated the protective effect of corticosterone (CORT), a representative stress hormone against hydrogen peroxide (H₂O₂)-induced neuronal cell death and its underlying molecular mechanism in SH-SY5Y cells, a human neuroblastoma cell line. The decreased cell viability by H₂O₂ was effectively restored by the pretreatment with low concentration of CORT (0.03 μM for 72 h) in the cells. H₂O₂-increased expression of apoptotic markers such as PUMA and Bim was decreased by CORT pretreatment. Furthermore, pretreatment of CORT attenuated H₂O₂-mediated oxidative damages by upregulation of antioxidant enzymes via activation of nuclear factor erythroid 2-related factor 2 (Nrf2). These findings suggest that low concentration of CORT with eustressed condition enhances intracellular self-defense against H₂O₂-mediated oxidative cell death, suggesting a role of low concentration of CORT as one of key molecules for resilience and neuronal cell survival.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.31 no.11
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• pp.1083-1092
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• 2007

The objective of the present paper is to evaluate the effect of the evolution of contact surface profile caused by fretting wear on fatigue life of press-fitted shaft by means of an analytical method based on experimental data. A finite element analysis was performed to analyze the stress states of press-fitted shaft, considering the worn contact profiles of shaft. The fatigue lives of the press-fitted shaft reflecting the evolution of contact stress induced by fretting wear were evaluated by stress-life approach using fatigue notch factor. It is found that the stress concentration of contact edge in press-fitted shaft decreases rapidly at the initial stage of total fatigue life, and its location shifts from the contact edge to the inside with increasing number of fatigue cycles. Thus the change of crack nucleation position in press-fitted shaft is mainly caused by the stress change of contact edge due to the evolution of contact surface profile by fretting wear. Furthermore, the estimated fatigue lives by stress-life approach at the end of running-in period of the fretting wear process corresponded well to the experimental results. It is thus suggested that the effect of fretting wear on fatigue life in press fits is strongly related to the evolution of surface profile at the initial stage of total fatigue life.

• Journal of the Korean Society for Precision Engineering
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• v.12 no.2
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• pp.154-161
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• 1995

In order to analysis of the stress distribution around flaws and the interaction effects between fatigue cracks, stress around micro hole was analyzed by Finite Element Method(F.E.M.) and micro hole specimens were tested using rotary bending fatigue machine and twisting fatigue machine to identify stress effects for fatigue cracks initiating from micro holes and interaction effects between micro holes. The results are as follows : Interaction effects of .sigma. $_{y}$for the micro hole side is larger than the large micro hole side when the interval between micro holes is near. Stress concentration factor increase as the diameter of micro hole becomes smaller. But, stress field of micro hole is smaller than that of large micro hole at h .leq. r (h:depth of micro hole, r:radius of micro hole) and that of large hole is larger than that of small micro hole at h >r expect the small range from micro hole.e.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.05a
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• pp.761-764
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• 2002

This paper deals with the stress concentration of the rotating disc in detail. We studied maximum stress of rotating disc with respect to the various parameter of circular hole such as position, size, number of the hole, then the mollified effect of maximum stress due to pin-hole around circular hole, using FEM, the results are as follows: 1. The more the number of circular hole and the further from the center, the maximum equivalent stress reduces. 2. When the pin-hole is located 60$^{\circ}$ from the x-axis, the maximum stress reduces significantly due to the effect of interference.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.9 s.180
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• pp.2252-2258
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• 2000

In order to investigate the effect of nozzle on stress concentration in pressure vessels, three dimensional finite element analyses were performed. The results were compared with those for corresponding two dimensional axisymmetric finite element analyses. A three dimensional finite element model with a surface crack was also designed to evaluate the effect of internal pressure and heat transfer on crack face, and the resulting stress intensity factors from the finite element analyses were compared with those for ASME Sec. XI and Raju-Newman's stress intensity factor solution. As a result, the validity of currently available stress intensity factor solutions for a surface crack was reviewed in the presence of geometrical complexity, heat transfer and internal pressure.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.4
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• pp.449-454
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• 2017

Recently, increasing attention has been paid to the welfare of farm animals, which have been evaluated using behavioral and physiological measures. However, so far, the measures have almost always been used to estimate poor welfare. In this review, firstly we focus on how oxytocin (OT) relates to positive social behavior, pleasure, and stress tolerance, and second on which management factors stimulate OT release. OT induces maternal and affiliative behaviors and has an anti-stress effect. Further, OT is produced during enjoyable events, and has positive feedback on its own release as well. Therefore, to some extent, the relationship of OT to positive normal behavior was mutually beneficial-heightened OT concentration owing to comfortable rearing conditions induces positive social behavior, which in turn may increase OT concentration. Hence, studies on animal welfare should pay more attention to increasing comfort and the stress tolerance, rather than only focusing on when stress occurs in farm animals.