Amid the recent growing social demand for wellness culture and healing tourism, I, through a literature survey and case study, reviewed the conditions of healing tourism in Gangwon-do as a destination of healing tourism, and examined the development project of Gangwon-do type healing tourism and commercialization of the wellness perspective. According to the survey, it was found that the Yeongdong area in Gangwon Province had excellent healing-based conditions in virtue of abundant natural resources, but it was found that it was necessary for local governments to cooperate in order to prevent overlapping investments and create synergy effects by connecting with one another as development contents or business items of healing tourism projects overlap or remain in the planning stage. In the case of Goseong-gun, which was reviewed as the main site, it has high potential as a silver-healing tour and if the County seeks a wellness merchandising strategy for each healing tourism target based on a therapy program linked with local specialized resources, and effectively links and specializes regional strengths in Gangwon-do's Yeongdong region, it is expected to become a regional success story of operating the development of the local tourism for silver and health-oriented tourists.
Currently, liver transplantation is the only available remedy for patients with end-stage liver disease. Conservation of transplanted liver graft is the most important issue as it directly related to patient survival. Carbonyl reductase 1 (CBR1) protects cells against oxidative stress and cell death by inactivating cellular membrane-derived lipid aldehydes. Ischemia-reperfusion (I/R) injury during living-donor liver transplantation is known to form reactive oxygen species. Thus, the objective of this study was to investigate whether CBR1 transcription might be increased during liver I/R injury and whether such increase might protect liver against I/R injury. Our results revealed that transcription factor Nrf2 could induce CBR1 transcription in liver of mice during I/R. Pre-treatment with sulforaphane, an activator of Nrf2, increased CBR1 expression, decreased liver enzymes such as aspartate aminotransferase and alanine transaminase, and reduced I/R-related pathological changes. Using oxygen-glucose deprivation and recovery model of human normal liver cell line, it was found that oxidative stress markers and lipid peroxidation products were significantly lowered in cells overexpressing CBR1. Conversely, CBR1 knockdown cells expressed elevated levels of oxidative stress proteins compared to the parental cell line. We also observed that Nrf2 and CBR1 were overexpressed during liver transplantation in clinical samples. These results suggest that CBR1 expression during liver I/R injury is regulated by transcription factor Nrf2. In addition, CBR1 can reduce free radicals and prevent lipid peroxidation. Taken together, CBR1 induction might be a therapeutic strategy for relieving liver I/R injury during liver transplantation.
This study attempts to understand the context of shared learning in the trading zone formed by teachers from different backgrounds and the process in which this shared learning varies in the educational context, focusing on the case of 'Woodwork Science Education Study Group.' To do this, data was collected through in-depth interviews with eight teachers who participated in the 'Woodworking Science Education Research Group' and analyzed their responses based on grounded theory. As a result, the causal conditions of the teachers' research group were 'various contexts of entering the trading zone' and the central phenomenon was 'encounter with learning in the trading zone.' Contextual conditions affecting this phenomenon were 'woodwork as a boundary object and individual transfiguration experience,' and action/interaction strategy was 'various efforts and influences in the field.' The intervention condition was 'practical effort and experience in educational field.' Final result in this model is 'the new practice of learning shared in the trading zone.' In selective coating, it was found that the practice of the teacher's research group appears as four types of' 'Extracurricular creative experience type,' 'career education type,' 'curricula education type,' and 'school management type.' The results of this study suggest that the shared learning and antonymous practice among teachers in the teachers' research group as trading zone do not only meet their learning needs but also lead to various teaching practices in the individual teachers' context of education and improve the diversity and quality of education.
This study suggests that even if the consulting is started by the consulting of the company, it is difficult for the consulting firm to operate the consulting firm Consulting performance differs depending on the degree of understanding of consulting. Although consulting firms have been studying various prior research papers in view of the fact that there are many cases where they proceed with the sales strategy of repurchasing in mind, most of them deal with research on consulting performance on the supplier side, The purpose of this study is to investigate whether a company has a high level of participation in consulting in the event of a situation or situation and consequently influences the intention to purchase consulting. In order to find out whether they are visible, the reliability of the measured values and the fit of the measurement model by CFA were obtained through the exploratory factor analysis. The results were as follows: The results of this study are as follows. As a result of the study, it is necessary for the consultant to improve the participation of the consulting company and the understanding of the consulting in order to increase the intention of the consulting repurchase intention. Since the consultant shows the result in an empirical way, the consulting company participates in the role and process The results of this study are as follows. First, it is suggested that firms should be very careful about the participation and consulting understanding because they affect the repurchase intention of consulting firms.
Hexaploid wheat (common wheat/bread wheat) is one of the most important cereal crops in the world and a model for research of an allopolyploid plant with a large, highly repetitive genome. In the heritability of agronomic traits, variation in gene presence/absence plays an important role. However, there have been relatively few studies on the variation in gene presence/absence in crop species, including common wheat. Recently, a reference genome sequence of common wheat has been fully annotated and published. In addition, advanced next-generation sequencing (NGS) technology provides high quality genome sequences with continually decreasing NGS prices, thereby dawning full-scale wheat functional genomic studies in other crops as well as common wheat, in spite of their large and complex genomes. In this review, we provide information about the available tools and methodologies for wheat functional genomics research supported by NGS technology. The use of the NGS and functional genomics technology is expected to be a powerful strategy to select elite lines for a number of germplasms.
This study recognizes that the externalizing problem behaviors of child with disabilities are the result of the social interaction between mother and child, and empirically verifies its systematic causal structure and multidimensional influence relationship. It was attempted to derive practical implications that can help the smooth normalization process of children's families. Therefore, 135 children with disabilities and their mothers selected by convenience sampling were targeted, and in the relationship between maternal overprotective parenting and externalizing behaviors of child, effortful control was used as a mediating variable, and defense style of mothers and children was used as a moderating variable. A Conditional Process Analysis(CPA) that can verify the moderated mediation Effect was performed by establishing a research model. As a result of the analysis, first, the overprotective parenting behavior of mother was statistically significant in both direct and indirect effects in increasing externalizing behaviors of child, and the mediation effect by effortful control was also statistically significant. Second, it was confirmed that the moderated mediation effect of effortful control by the mother's defense style was statistically significant, and the moderated mediation effect of effortful control by the child's defense style was not statistically significant. Based on the above results, assuming the importance of the influence of maternal parenting, a direct strategy for change in maternal overprotective parenting, child's Practical implications of parallel strategies with the tendency toward effective control and suboptimal strategies through the application of mothers' coping strategies were discussed.
This study examined the effectiveness of wind corridor construction by analyzing the thermal environment, cold air generation, ventilation, and geographical characteristics to improve urban thermal environment and establish the basis for specialized strategy in Changwon-si, Gyeongsangnam-do. Using spatial analysis and remote sensing techniques, surface temperature, land cover and land use, wind field, and slope were measured and through this, a wind corridor analysis model was constructed. As a result of the analysis as of 2020, Changwon-si generally has land cover characteristics that are advantageous for the generation of cold air, but the temperature in most urban areas is the highest, and the temperature in areas such as north Changwon area, Jinbukmyeon, Ung-dong, and Ungcheon-dong are relatively high. There was a typical trend of high average wind speed in mountain regions and low average wind speed in urban areas. Accordingly, the north Changwon area, the former Changwon downtown area, the Hogye-ri and Pyeongseong-ri areas, and the Changpo Bay area are derived as vulnerable areas to thermal environment, and various measures to reduce temperature and improve air quality that the inflow of cold air into the area considering the characteristics of each area and securing wind ventilation between the surrounding mountains, reservoirs, and park areas were proposed.
Purpose - As the growth potential of the cultural contents industry steadily grows, the cinemas industry is growing fast especially due to popularity and commerciality. The recent in the cinemas industry is evolving on multiplex cinemas that combine cultural facilities such as theaters, restaurants, and shopping centers. Due to the rapid growth of multiplex cinemas, many researchers have studied the characteristics of visiting customers in Korea. Among them, selection attribute of multiplex cinemas, including the service quality and physical environment, is important because it may examines the cause of customer 's behavior. Thus, this research focuses on the effects of the selection attributes of the multiplex cinemas on customer satisfaction and their loyalty. This research suggests the guidelines for how cinemas should manage their customers and build their customers satisfaction and loyalty that improve business performance. Research design, data, and methodology - This study tests the structural relationship between selection attributes of multiplex cinemas, customer satisfaction, and loyalty. selection attributes of multiplex cinemas divide into five sub-dimensions such as movies facility quality, services, cleanliness, accessibility, and snack bars quality. In order to examine the purposes of this research, research model and hypotheses were developed. All constructs were measured with multiple items developed and tested in the previous studies. The data were collected from 100 students in their 10-20s and were analyzed using SPSS 22.0, SmartPLS 3.0 and fsQCA program. Result - The findings of this research are as follows. First, all selection attributes except cleanliness have significant positive impacts on customer satisfaction and loyalty. Second, customer satisfaction has significant positive impact on loyalty. Third, as a result of fsQCA, high satisfaction and high accessibility were the necessary conditions on loyalty. Fourth, the necessary conditions for male and female groups were different. Conclusions - The implications of this study are as follows. Overall, multiplex cinemas should manage selection attributes basically regardless of the type of theater. Especially, cleanliness was not significant, but the customer probably consider it an essential and basic factors. Also, they are able to manage the selection attributes differently depending on the type of gender. For the male customers, it is effective that centralized strategy and for female customers, it is effective that emphasized the multiplex cinemas image.
Journal of the Korean Applied Science and Technology
/
v.37
no.6
/
pp.1575-1582
/
2020
This study aimed to provide basic data for establishing advertising strategy based on the value and implications of the image of the player by examining the influence of the image of a soccer player on the advertising effect. Therefore, a domestic soccer player selected as a sample the production population who experienced the advertisement selected as a model, and conducted a face-to-face (face-to-face) and non-face-to-face (mobile) survey for about 5 months from May 1 to September 30, 2020. Data from a total of 402 people were used for the final analysis. For data processing, frequency analysis, internal consistency and exploratory factor analysis, correlation analysis, and multiple regression analysis were performed using the SPSS (ver. 21.0) program. The main results of this study are as follows. First, it was found that the soccer player image impact the brand attitude of the advertising effect in the order of body and appearance, performance, reliability, attitude and morality. Second, it was found that the soccer player image impact the advertising attitude of the advertising effect in the order of performance, attitude and morality, body and appearance, reliability.
Journal of the Korean Association of Geographic Information Studies
/
v.23
no.4
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pp.234-252
/
2020
This paper is to verify the effectiveness of 'Hybrid Disaster Management Strategy' that integrates 'RTM(Real-time Monitoring) based On-line' and 'UAV based Off-line' system. For landslide prone area where sensors were installed, the conventional way of risk management so far has entirely relied on RTM data collected from the field through the instrumentation devices. But it's not enough due to the limitation of'Pin-point sensor'which tend to provide with only the localized information where sensors have stayed fixed. It lacks, therefore, the whole picture to be grasped. In this paper, utilizing 'Digital Photogrammetry Software Pix4D', the possibility of inference for the deformation of ungauged area has been reviewed. For this purpose, actual measurement data from RTM were compared with the estimated value from 3D point cloud outcome by UAV, and the consequent results has shown very accurate in terms of RMSE.
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