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The Effect of Sodium Alginate Coating on the Storage Stability and Dissolution Rate of Enteric Coated Lansoprazole (알긴산 나트륨이 장용코팅된 란소프라졸 제제의 저장안정성 및 용출률에 미치는 영향에 관한 연구)

  • Kim, Jung-Hoon;Oh, Jung-Min;Khang, Gil-Son;Jeong, Je-Kyo;Lee, Jung-Sik;Jeung, Sang-Young;Lee, Hai-Bang
    • Journal of Pharmaceutical Investigation
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    • v.32 no.4
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    • pp.277-284
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    • 2002
  • Lansoprazole, pharmaceutics for acid-related diseases, is unstable in low pH environments and generally coated with enteric polymer to obtain gastroresistance in stomach. Because its storage stability is influenced by acidic substitutes of enteric polymer, alkaline chemicals wεre generally addεd to dosage form as a stabilizer. In this experience, we coated lansoprazole bead with sodium alginate and evaluated the effect of bead size and sodium alginate coating on the storage stability and dissolution profile of lansoprazole. Sodium alginate solution containing lansoprazole was sprayed as a droplet into 3% (w/v) $CaCl_2$ solution and the resultant bead was coated with starch, sodium alginate, and hydroxypropyl methylcellulose phthalate. The content of lansoprazole granule not coated with sodium alginate decreased to 57.96% of initial content when stored at a severe condition for 4 weeks, but that of lansoprazole granule coated with sodium alginate before enteric coating decreased little and as the thickness of sodium alginate film increased, the content of bead didn't decreased for 4 weeks. Sodium alginate film also improved the gastroresistance without much influencing the maximum dissolution rate.

Measurement of the intrinsic speed of sound in a hot melt ceramic slurry for 3D rapid prototyping with inkjet technology (3차원 잉크젯 쾌속 조형법을 위한 세라믹 상변화 잉크의 음속측정)

  • Shin, Dong-Youn
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.9 no.4
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    • pp.892-898
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    • 2008
  • 3D rapid prototyping is the manufacturing technology to fabricate a prototype with the data stored in a computer, which differs from conventional casting technology in terms of an additive process. Various 3D rapid prototyping techniques such as stereolithograpy. fused deposition modeling. selective laser sintering, laminated object manufacturing have been developed but among them, 3D inkjet printing has a unique feature that materials could be jetted to directly form the body of a prototype, which could be a finished product functionally and structurally. However, this needs ink with a high solid content, which tends to increase the dynamic viscosity of ink. The increase of ink viscositytends to restrict the jettable range of ink and hence the jetting conditions should be optimized. The intrinsic speed of sound in a hot melt ink with ceramic nanoparticles dispersed is one of key components to determine the jettable range of ink. In this paper, the way to measure the intrinsic speed of sound in a hot melt ceramic ink is proposed and its influence on the jetting condition is discussed.

A Hangul Script Matching Algorithm for PDA (PDA상에서의 한글 필기체 매칭 알고리즘)

  • Cho, Mi-Gyung;Cho, Hwan-Gue
    • Journal of KIISE:Software and Applications
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    • v.29 no.10
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    • pp.684-693
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    • 2002
  • Electronic Ink is a stored data in the form of the handwritten text or the script without converting it into ASCII by handwritten recognition on the pen-based computers and Personal Digital Assistants(PDAs) for supporting natural and convenient data input. One of the most Important issue is to search the electronic ink in order to use it. We proposed and implemented a script matching algorithm for the electronic ink. Proposed matching algorithm separated the input stroke into a set of primitive stroke using the curvature of the stroke curve. After determining the type of separated strokes, it produced a stroke feature vector. And then it calculated the distance between the stroke feature vector of input strokes and one of strokes in the database using the dynamic programming technique. We did various experiments and our algorithm showed high matching rate over 97.7% for only the Korean script and 94% for the data mixed Korean with the Chinese character.

A Study on the Model of Internet Public Library in Korea (IPL-Korea) (인터넷 공공도서관 구축 모형 연구)

  • 고영만;오삼균
    • Journal of the Korean Society for information Management
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    • v.16 no.4
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    • pp.109-123
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    • 1999
  • We are faced with a paradox in the age of information as finding quality information on the Internet becomes a more challenging task because of information overload. This paper describes the prototype for “IPL-Korea” (Internet Public Library in Korea) project which is an attempt to provide the public with quality information in the form of a metadata system. The system involves cataloging of resources, i.e. websites, that are filtered by library and information science majors as well as information professionals. The user focus of this system is on children, youth, women, and seniors; various classification schemes and resource descriptions relevant for each user group are incorporated into the system to allow efficient browsing of the resources. A thesaurus for “IPL-Korea”, which is based on the ERIC thesaurus, is being constructed for easy manipulation of the breath of searching. The “IPL-Korea” metadata system employs the entity-relationship model in the design of its conceptual schema. Metadata is being stored in the Oracle database system and Web interfaces to this database are provided through ASP, ColdFusion, and JAVA technology.

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A study of algorithm for non-streaming synchronized data processing (비스트리밍 동기화 데이터 처리를 위한 알고리즘 연구)

  • Moon, Gwon-Jae;Yoo, Ji-Sang;Bang, Gun;Choi, Jin-Soo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.9A
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    • pp.746-753
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    • 2003
  • In this paper, we propose an efficient algorithm for non-streaming synchronized data processing based on ATSC-DASE in terrestrial digital data broadcasting services. Non-streaming synchronized data is encapsulated in DSM-CC sections with PTS(presentation time stamp) values associated with A/V and it is transmitted in a form of MPEG-2 TS(transport stream). At the receiver, the transmitted A/V data are processed by PC based set-top box(STB) in real-time, and the transmitted non-streaming synchronized data is also stored at the STB and is displayed at right time by the proposed algorithm. To verity the proper operation of the proposed algorithm, we make a scenario for non-streaming synchronized data by XML, and finally we are able to display it properly by using declarative application(DA) browser.

Study on Chromatology of the Five Cardinal Colors in Oriental Medicine (한의학(韓醫學) 오색(五色)의 색채론적(色彩論的) 연구)

  • Kim, Kyoung-Shin;Kim, Byoung-Soo
    • Journal of Haehwa Medicine
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    • v.20 no.1
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    • pp.25-37
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    • 2011
  • It fuses into culture of the East and the West in use of color ; colors of five direction, which had been from the Five Phase Theory in East Asia. Formative ability of color fields in a formative early Oriental Medicine history as well. Color is a very important factor and a necessary step of visible diagnosis. As a human's body is maintained and alive under the control of spirit and spirit is stored by five viscera, so spirit expresses the change of five viscera and is reflected by color. Visible diagnosis consists of spirit, appearance, Qi and color and movement. The purpose of each visible diagnosis is that we would know states of essence, Qi and spirit in patient's body. To ancient Asia people 'to see' was a kind of insight to the object as a whole. Similarily the activity of seeing the human body was the integral part of making diagnosis of a patient. This was the cause that there was suggested the discussion of the Five color theory in Oriental Medicine as a counterpart to that of the 'Goethe for Zur Farbenlehrer'. The inspection of Oriental Medicine was not a simple gazing of the eye as a sense organ, but the total insight to the internal state of the patient. For that reason, the eye-perception in early Chinese medicine was the reading the signs of the internal body which had have not the visual form but the flux of the internal life.

Obscene Material Searching Method in WWW (WWW상에서 음란물 검색기법)

  • 노경택;김경우;이기영;김규호
    • Journal of the Korea Society of Computer and Information
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    • v.4 no.2
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    • pp.1-7
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    • 1999
  • World-Wide Web(WWW) is a protocol for changing information exchanges which is central to text documents in the existing network to make a multimedia data exchanges. It is possible for a beginner to search and access data which he wants to find as data were stored in the form of hypertext. The easiness for searching and accessing the multimedia data in WWW makes a important role for obscene materials to be toward generalization and multimedia and occurs social problems for them to be commercialized, while other researchers have actively studied the way to block effectively the site providing obscene materials for solving such problems. This paper presents and implements the blocking method for the sites having obscene material as it effectively search them. The proposed model was based on Link-Based information retrieval method and proved that it accomplished more efficient retrieval of relevant documents than probabilistic model when compared the one with the other which is known to generate the most correct results. The improvements in the average recall and precision ratio were shown as 12% and 8% respectively. Especially, the retrieval capability of relevant documents which include non-text data and have a few links increased highly.

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Solid State Cesium Ion Beam Sputter Deposition

  • Baik, Hong-Koo
    • Proceedings of the Korea Association of Crystal Growth Conference
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    • 1996.06a
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    • pp.5-18
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    • 1996
  • The solid state cesium ion source os alumino-silicate based zeolite which contains cerium. The material is an ionic conductor. Cesiums are stably stored in the material and one can extract the cesiums by applying electric field across the electrolyte. Cesium ion bombardment has the unique property of producing high negative ion yield. This ion source is used as the primary source for the production of a negative ion without any gas discharge or the need for a carrier gas. The deposition of materials as an ionic species in the energy range of 1.0 to 300eV is recently recognized as a very promising new thin film technique. This energetic non-thermal equilibrium deposition process produces films by “Kinetic Bonding / Energetic Condensation" mechansim not governed by the common place thermo-mechanical reaction. Under these highly non-equilibrium conditions meta-stable materials are realized and the negative ion is considered to be an optimum paeticle or tool for the purpose. This process differs fundamentally from the conventional ion beam assisted deposition (IBAD) technique such that the ion beam energy transfer to the deposition process is directly coupled the process. Since cesium ion beam sputter deposition process is forming materials with high kinetic energy of metal ion beams, the process provider following unique advantages:(1) to synthesize non thermal-equilibrium materials, (2) to form materials at lower processing temperature than used for conventional chemical of physical vapor deposition, (3) to deposit very uniform, dense, and good adhesive films (4) to make higher doposition rate, (5) to control the ion flux and ion energy independently. Solid state cesium ion beam sputter deposition system has been developed. This source is capable of producing variety of metal ion beams such as C, Si, W, Ta, Mo, Al, Au, Ag, Cr etc. Using this deposition system, several researches have been performed. (1) To produce superior quality amorphous diamond films (2) to produce carbon nitirde hard coatings(Carbon nitride is a new material whose hardness is comparable to the diamond and also has a very high thermal stability.) (3) to produce cesiated amorphous diamond thin film coated Si surface exhibiting negative electron affinity characteristics. In this presentation, the principles of solid state cesium ion beam sputter deposition and several applications of negative metal ion source will be introduced.

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Smart Platform Strategies for Smart Korea (스마트코리아 추진을 위한 스마트 플랫폼 구현 전략)

  • Yoon, Yong-Ik;Kim, Eun-Ju;Um, Lee-Young
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.12
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    • pp.235-246
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    • 2011
  • We are living in the era of globalization, convergence of multi technologies and dual service system especially in the cultural, social, political, economical and technical aspects. These waves are making us go beyond Information Society and urge to enter the Smart Society. In the past, we have focused only on creating, proceeding and accumulating vast amount of information. Where as today, we are hoping to be provided with more intellectual, cheep, and converged form with the help of stored information without any space and time constraints. In this thesis, with consideration of the knowledge based society service integration paradigm, we will first look at the concept of Smart Service with various case studies, proposition strategy implementation on Smart Platform by analysing the service the implementing aspect, looking at the roles of each related divisions, and measuring the secure elements etc.

Carbonation of coal fly ash for construction materials (탄산화 건자재 제조를 위한 석탄 비산회의 탄산화)

  • Park, Jun-Young;Kim, Yoo-Taek;Kim, Hyun-Jung
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.22 no.3
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    • pp.147-151
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    • 2012
  • Carbon dioxide ($CO_2$) could be stored in the form of Ca and Mg compounds including alkaline earth metal by carbonation. The possibility of $CO_2$ storage was tested by using desulfurized ash from fluidized bed type boiler as raw material. Autoclave was used for maintaining the reaction pressure and temperature for the carbonation. The analysis of weight change rate, XRD, and TG/DTA proved that more than 15 % of carbonation rate was obtained under 10 $kgf/cm^2$ and $120^{\circ}C$-10 min.