• Proceedings of the KIEE Conference
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• 1994.07a
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• pp.144-146
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• 1994

We manufactured amorphous core for 1 KVA transformer by lap-step and one cut method, and measured the magnetic characteristics of the cores as a function of the number of ribbons per group, the number of group per set. the air gap and radius of core edge.

• Proceedings of the KIEE Conference
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• 1994.07a
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• pp.79-81
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• 1994

A solution of magnetic fields for amorphous core transformer has been tried using homogenization technique. The technique, which is derived by applying asymptotic expansion to the standard finite element method, is helpful to analyse a joint part of amorphous core transformer microscopically. A butt-lap-step joint type of lamination method is modeled and its equivalent reluctivity is calculated to analyse various quantities of the magnetic fields. The algorithm is also applicable to other electric devices which have complicated material structure with repeated patterns.

• Fashion & Textile Research Journal
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• v.2 no.5
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• pp.423-429
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• 2000

This study was conducted to find out the relationship between skin temperature and clothing temperature in body parts. Four different kinds of fabrics were used in this experiment. These fabrics were a (Ny/Spun, 81.8/18.2%), b (Wool/Poly/span, 50/45/5%), (Wool/Ny/Span70/25/5) and d (Wool/Poly/Span 45/45/10%). The subjects skated at indoor ice rink where the length was 111.12 m, the temperature was $11{\pm}1^{\circ}C$ and the humidity was $70{\pm}10%$. The four an male professional skaters speed was $17{\pm}1$ seclm/lap. Physiological parameters were skin temperature at 4 body points (chest, upper arm, thigh, leg) and clothing temperature at chest was measured every 15 second. Experiment protocol was as follows: resting before skating (5 min.), skating (5 min.), and resting after skating (10 min.). The results were as follows; The mean skin temperature by fabrics shows b > a > d > c. The mean skin temperature began to decline little by little as soon as the subjects entered the indoor ice rink. After they rested for five minutes, they started skating and the mean skin temperature declined widely. After skating, the mean skin temperature increased step by step. It maintained the similar temperature. The value of skin temperature at body points shows Leg > Chest > Upper arm > Thigh. Because of the characteristics of skating uniforms, the skin temperature of the leg is the highest. The skating uniform was designed to have a protective portion in the leg. The chest produces the highest temperature in the body. The comparison of difference values in skin temperature show Thigh > Upper arm > Chest > Leg. While skating in a cold atmosphere, the largest difference value is clothing temperature. The clothing temperature is lower than the skin temperature during skating. The difference value of clothing temperature is larger than the skin temperature of the chest.

• Molecules and Cells
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• v.44 no.9
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• pp.688-695
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• 2021

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has become a global health concern. Various SARS-CoV-2 vaccines have been developed and are being used for vaccination worldwide. However, no therapeutic agents against coronavirus disease 2019 (COVID-19) have been developed so far; therefore, new therapeutic agents are urgently needed. In the present study, we evaluated several hepatitis C virus direct-acting antivirals as potential candidates for drug repurposing against COVID-19. Theses include asunaprevir (a protease inhibitor), daclatasvir (an NS5A inhibitor), and sofosbuvir (an RNA polymerase inhibitor). We found that asunaprevir, but not sofosbuvir and daclatasvir, markedly inhibited SARS-CoV-2-induced cytopathic effects in Vero E6 cells. Both RNA and protein levels of SARS-CoV-2 were significantly decreased by treatment with asunaprevir. Moreover, asunaprevir profoundly decreased virion release from SARS-CoV-2-infected cells. A pseudoparticle entry assay revealed that asunaprevir blocked SARS-CoV-2 infection at the binding step of the viral life cycle. Furthermore, asunaprevir inhibited SARS-CoV-2 propagation in human lung Calu-3 cells. Collectively, we found that asunaprevir displays broad-spectrum antiviral activity and therefore might be worth developing as a new drug repurposing candidate for COVID-19.