• Title/Summary/Keyword: Stem design

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Comparison of Quality of Life of Autologous and Allogeneic Hematopoietic Stem Cell Transplantation Recipients (자가 조혈모세포 이식환자와 동종 조혈모세포 이식환자의 삶의 질의 비교)

  • Kim, Eun-Ji
    • Asian Oncology Nursing
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    • v.8 no.1
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    • pp.50-60
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    • 2008
  • Purpose: The purpose of this study was to compare Quality of life (QOL) in type and time after Hematopoietic stem cell tansplantation (HSCT) for patients with hematologic cancer. Method: This study was cross-sectional. The autologous recipients was 120, the allogeneic recipients was 237. The obtained data were analyzed using T-test, One-way ANOVA, Scheffe's test. Results: No significant differences were total QOL between the autologous and allogeneic recipients. But the autologous recipients reported better status than the allogeneic recipients in physical domain, especially 1-3 yr after HSCT. There was poorer QOL of 1-3 yr compared to 1 yr after HSCT in physical, psychological and social domain between the two groups. QOL in time after HSCT of the autologous recipients was significance differences in psychological, social domain. And QOL in time after HSCT of the allogeneic recipients was significant differences in physical, psychological and social domain. Conclusions: QOL of recipients undergoing HSCT is recovered beyond 3 yr point. Accordingly, long term care and service is essential to recipients undergoing HSCT. And further studies with a longitudinal design are necessary.

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Effects of Back Massage on Immune Response, Symptom Distress and Mood State of Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation (등 마사지가 동종 조혈모세포이식 환자의 면역반응, 신체증상 및 정서상태에 미치는 효과)

  • Song, Byung-Eun;Yoo, Yang-Sook;Cho, Ok-Hee
    • Korean Journal of Adult Nursing
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    • v.21 no.3
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    • pp.269-280
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    • 2009
  • Purpose: To examine the effect of back massage on immune response, symptom distress, and mood state of patients undergoing allogeneic hematopoietic stem cell transplantation (allogeneic HSCT). Methods: Subjects were thirty-seven patients undergoing sibling allogeneic HSCT (including 16 in the experimental group and 21 in the control group). Experimental subjects participated in an intervention group of back massage for 10 minutes, once a day and 5 times a week, from one week prior to the HSCT to the third week after the HSCT or a control group. A non-equivalent pretest-posttest design was used. t-test and Repeated measures ANOVA were used to examine group differences by using SAS. Results: No significant group differences were found in Immune response (CD4+, CD8+,CD19+, CD56+) and symptom distress. The experimental group had significantly less mood state (anxiety, confusion) than the control group. Conclusion: The back massage for the patients undergoing allogeneic HSCT may be effective in altering the anxiety and confusion during hematopoietic stem cell transplantation. However, this study did not provide evidence in improving immune response and symptom distress.

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An Exploratory Study of Middle School Students' Motivation in Science: Comparing a STEM Education Program in Korea and the USA

  • Lee, Hyonyong;Longhurst, Max L.;Freeman, Michael K.;Lee, Hyundong
    • Journal of Science Education
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    • v.43 no.1
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    • pp.1-16
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    • 2019
  • This exploratory study is aimed at exploring the validity of the Science Motivation Questionnaire (SMQ) developed for university students, to measure the science motivation of middle school students and analyze the differences on gender and country factors of SMQ. A total of 371 students participated in this study: 171 middle school students from the USA and 200 secondary students from Korea. All participants were enrolled in the STEM program and activities in Utah, USA (for US students) and at a Korean university institute for gifted and talented students (for Korean students). In this study, exploratory and confirmatory factor analyses and latent mean analysis were used to analyze the gender and country differences. The results indicated that the 25 items of SMQ scale were theoretically meaningful and valid for middle school students. The latent mean difference by gender indicated that male students have higher intrinsic motivation, career motivation, grade motivation, and self-determination than female students. Moreover, a significant difference exists in these factors between the two countries. Further findings reveal that Korean students scored higher than US students in terms of the aforementioned factors. This study will provide significant insights in and contribution to science motivation issues in STEM education and the development of design-based engineering programs.

The Effect of Aerobic Exercise Program on Health Status and Physical Fitness in Patients after the Stem Cell Transplantation (유산소 운동이 조혈모세포이식자의 건강상태와 체력에 미치는 효과)

  • Han, Shin-Hi
    • The Korean Journal of Rehabilitation Nursing
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    • v.4 no.1
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    • pp.7-19
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    • 2001
  • The Objectives of this research is to determine the effect of aerobic exercise program on health status and physical fitness in patients after the stem cell transplantation. This research design is one-group pretest-post test design. Sixteen subjects were selected from one university hospital in Seoul for the study, they was carried out aerobic exercise three to five times a week for 12 weeks. The period of data collection was from February to July, 2000. The collected data was analysed by descriptive analysis, paired t-test, content analysis SAS program was used for the statistical analysis. The results are as follows : 1. There was a significant improvement in the Physical functioning, Vitality and Reported change (t=2.39, p=0.03; t=2.35, p=0.03; t=2.58, p=0.02) but no change was observed in the Role physical, General health perception, Bodily pain, Social functioning, Role emotional and Mental health. 2. There was a significant improvement in the physical fitness (higher VO2 max, t=2.43, p=0.02; lower systolic pressure, t=-4.09, p=0.001; lower diastolic pressure, t=-3.43, p=0.002; lower pulse rate, t=-3.43, p=0.004; higher muscle sustaining power, t=2.79, p=0.015; higher muscle power, t=5.18 p=0.000; higher power of beginning, t=5.55, p=0.001; higher the sense of equilibrium, t=3.57, p=0.003; higher Hemoglobin, t=5.92, p=0.000; higher Hematocrit, t=5.38, p=0.000). Therefore, this study will provide a theoretical back ground for patients after stem cell transplantation to understand the importance of physical exercise and maintain physical exercise; and for other researches to refer to the results for exercise protocol of rehabilitation program.

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A Study on Bow Hull Form and Icebreaking Capability of Icebreaking Vessels (빙해항행선박의 선수부 형상과 쇄빙능력에 관한 연구)

  • K. Choi;C.B. Son;E.G. Paeng
    • Journal of the Society of Naval Architects of Korea
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    • v.29 no.4
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    • pp.87-97
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    • 1992
  • Of various design factors affecting icebreaking capability of an icebreaker, the stem angle(i.e., angle between bow stem and ice sheet) is the most important one under continuous icebreaking operation. This study focuses on the relationship between the bow stem angle of an icebreaker and its icebreaking capability. Considering relatively high loading-rate conditions with typical advancing speed of 3 to 4 knots, the material properties and deformation characteristics of sea ice are regarded as entirely elastic and brittle. In this paper the interaction process of icebreaker with level ice is simplified as a beam of finite length supported by Winkler-type elastic foundation simulating water buoyancy. The wedge type ice beam is loaded by the vertical impact forces due to the inclined bow stem of icebreaking vessels. The numerical model provides locations of maximum bending moment where extreme tensile stress arises and also possible fracture occurs. The model can predict a characteristic length of broken ice sheet upon the given environmental and design parameters.

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Microwave Assisted Extraction, Optimization using Central Composite Design, Quantitative Estimation of Arjunic Acid and Arjunolic Acid using HPTLC and Evaluation of Radical Scavenging Potential of Stem Bark of Terminalia arjuna

  • Khatkar, Sarita;Nanda, Arun;Ansari, S.H.
    • Natural Product Sciences
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    • v.23 no.2
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    • pp.75-83
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    • 2017
  • The optimization and microwave assisted extraction of stem bark of Terminalia arjuna, quantitative estimation of the marker compounds arjunic acid and arjunolic acid using HPTLC and the evaluation of free radical scavenging activity has been performed in this study. The central composite design was used for optimization and the values of parameters for optimized batch of microwave assisted extraction were 1000 W (Power), 3 minutes (Time) and 1/120 (Solid/solvent ratio). The solvent system to carry out the HPTLC was toluene: acetic acid: ethyl acetate (5: 5: 0.5) and quantitative estimation was done using standard equations obtained from the marker compounds. The in-vitro free radical scavenging activity was performed spectrophotometrically using ascorbic acid as standard. The value of estimated percentage yield of arjunic acid and arjunolic acid was 1.42% and 1.52% which upon experimentation was obtained as 1.38% and 1.51% respectively. The DPPH assay of the different batches of microwave assisted extraction and marker compounds taken suggested that the marker compounds arjunic acid and the arjunolic acid were responsible for the free radical scavenging activity as the batch having the maximum percentage yield of the marker compounds showed best free radical scavenging effect as compared to standard ascorbic acid. The $IC_{50}$ value of the optimized batch was found to be 24.72 while that of the standard ascorbic acid was 29.83. Hence, the yield of arjunic acid and arjunolic acid has direct correlation with the free radical scavenging activity of stem bark extract of Terminalia arjuna and have potential to serve as active lead compounds for free radical scavenging activity.

Development of a Water-Spraying Type Automatic Glochids Removal System for Cactus (Opuntia humifusa) Stem

  • Jang, Ik Joo;Park, Tusan;Ha, Yu Shin
    • Journal of Biosystems Engineering
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    • v.41 no.3
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    • pp.201-207
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    • 2016
  • Purpose: A water-spraying type automatic glochids removal system for cactus (Opuntia humifusa) stem was developed, and its performance was evaluated. The system was developed to reduce intensive human labor in removing glochids from cactus stem skin without inducing damage prior to further processing into value-added products. Methods: The developed system consists of conveyor and water-spraying systems. The conveyor system delivers cactus stems through water-spraying compartments and finally to a collecting box. In order to remove the glochids, rotating nozzles spray water over all areas (i.e., front and back faces and sides) of the cactus skin under controlled water pressure. Operating conditions such as conveyor speed, water pressure, angle of water-spraying nozzles, distance between conveyor belt and rotating nozzles, and angle of cactus flipping slide were adopted from our previous study and applied on the system design and manufacturing. The performance of glochids removal was evaluated by counting the number of glochids on the cactus stem before and after processing on the system. Results: The developed system performed efficiently and effectively under the pre-studied operating conditions except for the angle of cactus flipping slide. The new system had a glochids removal ratio of 94.1% without damaging the cactus skin. Considering the original number (approximately 30-60) of glochids, the remaining number was low (1-4), and most of them were found at the side edge of the cactus stem. This system can remove glochids from 360 cactus stems in 1 hr regardless of cactus size. Conclusions: The performance of the new system in glochids removal without damaging cactus skin is superior to any other existing device (i.e., brush type, rubber-friction type, and agitation type). The system is expected to be applied in cactus (O. humifusa) processing facilities.

The Role of Science Knowledge Application in Improving Engineering Problem Solving Skills

  • Nam, Younkyeong;Chae, Jimin
    • Journal of the Korean earth science society
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    • v.40 no.4
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    • pp.436-445
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    • 2019
  • This study presents how two types of integrated science and engineering lessons affect students' engineering problem solving skills and their perceptions of engineering. In total, 146 middle school students participated in this study. Eighty-six students participated in the Type I lesson (complete engineering design lesson with a science knowledge application) and 60 students participated in the Type II lesson (engineering design without a science knowledge application). Two main datasets, (1) students' Creative Engineering Problem Solving Propensity (CEPSP) measurement scores and (2) open-ended survey questions about students' perceptions of engineering, were collected before and after the lessons. The results of this study show that after participating in the Type I lesson, students' CEPSP scores significantly increased, whereas the CEPSP scores of the students who participated in the Type II lesson did not increase significantly. In addition, students who participated in the Type I lesson perceived engineering and the engineering integrated science lesson differently compared to the students who participated in the Type II lesson. The results of this study show that engineering integrated science, technology, engineering & mathematics (STEM) lessons should include a complete engineering design and a science knowledge application to improve students' engineering problem solving skills.

Member Selection Procedure in the Steel Structural Design (강구조물설계에서 부재선정의 시스템화 방법론)

  • 이영호;김상철;김흥국;이병해
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 1995.10a
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    • pp.197-206
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    • 1995
  • In structural design procedure, The procedure of member selection manages complex data relationship and reflects structural expert's knowledge. It is a difficult problem to construct an effective system with the conventional l programming technique. Knowledge_based s!'stem is a software system capable of supporting the explicit representation of expert's knowledge in member selection process through member data and reasoning mechanisms. This study describes useful methodology for structuring knowledge and representing relation between member data and knowledge. And this study shows the application of this member for member selection in the steel structural design.

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