• Bulletin of the Korean Chemical Society
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• v.27 no.11
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• pp.1741-1746
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• 2006

3D-QSARs on the neuroblocking activities by 1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine analogues as agonist at the nicotinic acetylcholine receptor (nAChR) were studied quantitatively using CoMFA and CoMSIA methodologies. The statistical results of CoMFA (A5: $r^2\;_{cv.}\;=\;0.707\;&\;r^2\;_{ncv.}$= 0.986) and CoMSIA model (A3: $r^2\;_{cv.}$ = 0.715 & $r^2\;_{ncv.}$ = 0.961) showed the best predictability and fitness for neuroblocking activity based on the cross-validated value and non-cross validated value. The steric and H-bond acceptor nature of a compound were essential for high activity. The study on 3D-QSARs between substrate molecules and their neuroblocking activities appears to be an useful approach for designing better neuroblocking drug development.

• The Journal of the Korean life insurance medical association
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• v.2 no.1
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• pp.143-151
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• 1985

In medical selection of Daehan Education Insurance, We doubted that 140 cases(male 117 cases, female 23 cases) might have the fatty infiltration of the liver by ultrasonography. We examined the weight and the hypertension of 140 patients by biochemically analyzing the blood extracted under fasting according to the age-distribution. The results are as follows: 1. 90% out of them had body weight than normal subject. 34.29% out of them were hypertension patients and most of them were $30{\sim}39's$ and $40{\sim}49's$. 2. As compared with the normal subjects in serum lipid value, HDL cholesterol value was low, but total cholesterol, Triglyceride, phospholipid and total lipid value were significantly high. Especially the statistical value of Triglyceride was very significantly high. 3. Total abnormal rate of sGOT value in Liver function test is 34.43% and the mean value of it is 66 unit and the abnormal rate of sGPT value is all 3.14% and the value of it is 70 unit. 4. The abnormal rate of Alkaline phosphatase value is 9.29% and the abnormal rate of total Bilirubine value is 14.29%. As HBsAg positive rate is 2.14% and HBs Ab positive rate is 31.43%, the positive rate of HBsAg represents Lower positive rate than Korean mean value. 5. The abnormal rate of the fasting blood glucose is 15.00% and the abnormal rate of Blood sugar pc 2hrs is 30.71%. 6. The abnormal case of protein, Albumin, Globulin, BUN, craetinine and Hemoglobin value was not found to any of them and in the above liver function test except serum lipid value, the rate not showing the abnormal value represents 45.3%(male) and 52.17%(female).

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2006.05a
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• pp.83-84
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• 2006

• Transactions of the Korean Society of Automotive Engineers
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• v.4 no.4
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• pp.130-139
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• 1996

The silicon carbide particles reinforced aluminium 6061($SiCp/A\ell$) composites are generally known have wild range of applications from automobiles to airospaces. But, by the results of existing study for $SiCp/A\ell$ composites, there are reports that the fatigue life of $SiCp/A\ell$ composites has improved than $A\ell$matrixes and has not improved then $A\ell$ matrixes. Consequently, in order to perform the reliable life prediction for $SiCp/A\ell$, the properties of probability distribution of fatigue crack initiation life & fracture life, crack growth length in constant number of cycles, crack growth rate in constant stress intensity factor range and m & C value in Paris's fatigue crack growth law and the estimation of statistical parameters have been evaluated by the statistics method.

• Journal of the Korean Home Economics Association
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• v.35 no.2
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• pp.283-296
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• 1997

The purpose of this study was to develope a housing suitable for the Korean elderly by analyzing traditional minds on housing of the middle-aged. Data were collected by the questionnaire from 696 middle-aged in 40's and 50's living in Chinju area. Collected data were analyzed by using statistical methods of One-Way MANOVA, scheffe's test, and multiple regression analysis which were processed with SAS. Following are results. 1) Middle aged people had four main traditional factors in their minds: a propensity toward traditional indoor atmosphere, traditional housing space, traditional housing value and ceremony space & traditional life style. 2) Socio-demographically, a propensity toward traditional housing space and ceremony space & traditional life style were significantly different between sexes, but not by educational level and income. A propensity toward traditional indoor atmosphere and ceremony space & traditional life style were different between housing types. 3) However, there were a significant difference between variables such as sex, educational level, income and housing type in residential demands for the elderly life. 4) Sex, housing type, a propensity toward traditional housing space and traditional housing value influenced residential demands for the elderly life I indoor and outdoor environments, nearby facilities and available services all of which were minor items in the demand for the elderly life.

• KDI Journal of Economic Policy
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• v.36 no.4
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• pp.103-133
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• 2014

We consider the economic value of emergency medical facilities. An emergency medical facility affects the medical environments in a community, and thus the social demand on the facility increases as the demand of qualified public health service increases. Regarding the increased demand and the limited resources of fiscal budget, it is important to scientifically evaluate the social benefit of the public investment on emergency medical facilities, as the results of evaluation can help make better budgetary decision on each public investment project of emergency medical facilities. In this paper, we try to estimate the economic value of emergency medical facilities based upon the estimated changes in preventable death rate by the facility and the statistical value of life. We hope the results contribute to improve the budgetary decision making on the emergency medical facility projects, thus the public health policies.

• Structural Engineering and Mechanics
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• v.20 no.1
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• pp.85-110
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• 2005

This paper aims at formulating various statistical models for the study of a ten year Weigh-in-Motion (WIM) data collected from various WIM stations in Hong Kong. In order to study the bridge live load model it is important to determine the mathematical distributions of different load affecting parameters such as gross vehicle weights, axle weights, axle spacings, average daily number of trucks etc. Each of the above parameters is analyzed by various stochastic processes in order to obtain the mathematical distributions and the Maximum Likelihood Estimation (MLE) method is adopted to calculate the statistical parameters, expected values and standard deviations from the given samples of data. The Kolmogorov-Smirnov (K-S) method of approach is used to check the suitability of the statistical model selected for the particular parameter and the Monte Carlo method is used to simulate the distributions of maximum value stochastic processes of a series of given stochastic processes. Using the statistical analysis approach the maximum value of gross vehicle weight and axle weight in bridge design life has been determined and the distribution functions of these parameters are obtained under both free-flowing traffic and dense traffic status. The maximum value of bending moments and shears for wide range of simple spans are obtained by extrapolation. It has been observed that the obtained maximum values of the gross vehicle weight and axle weight from this study are very close to their legal limitations of Hong Kong which are 42 tonnes for gross weight and 10 tonnes for axle weight.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.821-824
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• 2008

This paper presents a systematic approach for estimating material performance of concrete mixture design based on satisfaction curves developed from statistical evaluation of existing or newly obtained material property related data. In performance based material design (PBMD) method, concrete material used for construction of a structure is designed considering a structure's specified performance requirements based on its usage and characteristics such as environmental conditions, structure types, expected design life, etc.Satisfaction curves express the probabilities that one component of substrates (i.e., aggregate size, cement content, etc) of concrete mixture will sustain different criterion value for a given concrete mixture design. This study presents a statistical analysis method for setting up concrete material parameter versus concrete criterion relationships in the form of satisfaction curves and for estimating confidence bounds on these satisfaction curves. This paper also presents an analysis method to combine multiple satisfaction curves to form one unique satisfaction curve that can relate the performance of concrete to a single evaluating value. Based on several evaluated mixture design examples for various material properties, the validity of the proposed method is discussed in detail.

• Journal of agriculture & life science
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• v.44 no.6
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• pp.147-157
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• 2010

This study was carried out to develop the normal temperature-circulatable retort sterilized imitation crab leg (RSIC) with long shelf-life by retort sterilization. We have examined the optimum retort sterilization conditions and quality characteristics of the RSIC. Central composite design for response surface methodology (RSM) was adopted for optimization of retort sterilization, and experimental central composite design consisted of 11 samples such as 4 factorial points; 4 star points; 3 central points. Sterilization temperature and $F_0-value$ for retort sterilization were chosen for independent variables, and shearing force, whiteness and sensory score about texture were selected as a dependent variable. As a results of RSM analysis, multiple response optimization for the RSIC by Minitap statistical programing was $F_0-value$ 3.3 min. at $117.5{^{\circ}C}$. Also RSM analysis indicated such as sterilization temperature during retort sterilization was the most influential factor, while $F_0-value$ little affected on quality of the RSIC.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.41 no.2
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• pp.141-152
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• 2018

Although the 1997 Raw Data of the National Wealth Statistical Survey (South Korea) is timely 20-year-old data, it is meaningful as a benchmarking in the capital stock estimations of Korea, which is estimated by PIM (permanent inventory method). In the case of machinery/equipment, it is the data that can analyze in depth the changes in the industrial structure of Korea. In the case of ASL (average service life) which has economic concept, since the change of ASL is not so large, ASL yielded by the Raw Data of the 1997 National Wealth Statistical Survey is meaningful as reference value for the ASL estimated by the Bank of Korea and the National Statistical Office. As you know Japan has changed its service life due to changes in its industrial structure. However, many of its assets are still used for the years indicated in Showa (before 1989). The same trend with other countries such as Japan. However, the United States is constantly devoted to assessing the useful ASL and value of assets by distinguishing between the Hulten-Wykoff models and those not. Korea has also benchmarked the useful ASL of the United States and Japan when it conducted its own survey every 10 years by due diligence until 1997. In this study, the 'constraint' Iowa curve estimation by the Raw Data of the 1997 National Wealth Statistical Survey is based on the age records of the assets and the maximum age of the assets appropriately derived. And then we made modified Iowa curve by smoothing. From this modified one, we suggested ASL by asset. After 1997, the vintage disposal data directly were collected by the National Statistical Office with Oh Hyun Seung, Cho Jin Hyung, in order to estimate the useful ASL. Since then, the B/S team of the Economic and Statistics Bureau of the Bank of Korea has been working on a new concept of content training.