• Analytical Science and Technology
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• v.17 no.5
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• pp.388-392
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• 2004

Structural studies of membrane proteins, importantly involving interpretation of genomics information, many signaling pathway and major drug target for drug discovery, are having difficulty in characterizing the function using conventional solution nmr spectroscopy and x-ray crystallography because phospholipid bilayers hindered fast tumbling and crystallization. Here, we studied the structure of the pf1 coat protein in oriented phospholipid bilayers by home-built solid-state NMR probe. Bacteriophage pf1 was purified from Paeudomonas Aeruginosa and coat protein of bacteriophage pf1 was isolated from DNA and other proteins.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.38 no.2
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• pp.137-144
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• 2001

In this paper, a state assignment algorithm was proposed to reduce power consumption in control-flow oriented finite state machines. The Markov chain model is used to reduce the switching activities, which closely relate with dynamic power dissipation in VLSI circuits. Based on the Markov probabilistic description model of finite state machines, the hamming distance between the codes of neighbor states was minimized. To express the switching activities, the cost function, which also accounts for the structure of a machine, is used. The proposed state assignment algorithm is tested with Logic Synthesis Benchmarks, and reduced the cost up to 57.42% compared to the Lakshmikant's algorithm.

• Bulletin of the Korean Chemical Society
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• v.34 no.1
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• pp.211-220
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• 2013

The characteristic fluorescence properties of quercetin (QCT) and apigenin (API) were studied in various $CH_3OH-H_2O$ and $CH_3CN-H_2O$ mixed solvents. The structure of QCT is completely planar. API is not planar at the ground state but becomes nearly planar at the excited state. If the molecules are excited to the $S_1$ state in organic solvents, QCT exhibits no fluorescence due to excited state intramolecular proton transfer (ESIPT) between the -OH and the carbonyl oxygen, but API shows significant fluorescence because ESIPT occurs slowly. If the molecules are excited to the $S_2$ state, both QCT and API exhibit strong $S_2{\rightarrow}S_o$ emission without any dual fluorescence. As the $H_2O$ composition of both solvents increases, the fluorescence intensity decreases rapidly due to the intermolecular hydrogen bonding interaction. The theoretical calculation further supports these results. The change in fluorescence properties as a function of the solvatochromic parameters was also studied.

• Bulletin of the Korean Chemical Society
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• v.11 no.4
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• pp.309-313
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• 1990

The rates of solvolysis of trans-$[Co(N-eten)_2Cl_2)$+ (N-eten; N-ethylethylenediamine) have been investigated using spectrophotometric method in binary aqueous mixtures containing methyl alcohol, isopropyl alcohol, t-butyl alcohol, ethylene glycol and glycerol. The values of ${\Delta}H^{\neq}$ and ${\Delta}S^{\neq}$ obtained from temperature effect on the rate constants were $80{\sim}84 kJmol^{-1}$ and $- 28{\sim} - 45 JK^{-1}mol^{-1}.$ Extrema found in the variation of the enthalpy and entropy of activation with solvent composition correlated very well with extrema in the variation of the physical properties of mixture which relate to sharp change in the solvent structure. The reaction mechanism was discussed in terms of correlation diagrams involving the exess molar Gibbs function of mixing for the binary mixtures. The behavior of this cobalt(Ⅲ) complex was compared with that of t-butyl chloride. The application of free energy cycle to the process initial state to transition state in water and in the mixture showed that the solvation of transition state had dominant effect on the rates in the mixtures. It was found that $S_N1$ character was increased with increasing the content of co-solvent in the mixture.

• Wind and Structures
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• v.21 no.6
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• pp.609-623
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• 2015

Seismic reliability analysis of a jacket-type support structure for an offshore wind turbine was performed. When defining the limit state function by using the dynamic response of the support structure, a number of dynamic calculations must be performed in a First-Order Reliability Method (FORM). That means analysis costs become too high. In this paper, a new reliability analysis approach using a static response is used. The dynamic effect of the response is considered by introducing a new parameter called the Peak Response Factor (PRF). The probability distribution of PRF can be estimated by using the peak value in the dynamic response. The probability distribution of the PRF was obtained by analyzing dynamic responses during a set of ground motions. A numerical example is presented to compare the proposed approach with the conventional static response-based approach.

• Lingua Humanitatis
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• v.1 no.1
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• pp.195-217
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• 2001

According to John Crowe Ransom, "the poem is a loose logical structure with an irrelevant local texture." As is implied in the opposition between "structure" and "texture," Ransom′s is a dualistic, that is, non-organic, theory of poetry, in which the poem′s sound does not have any expressive function while its figurative language always goes beyond the realm of abstract meaning and celebrates the ontological density of the world. His theory relies heavily upon a series of oppositions-poetry and prose, art and science, concrete and universal, artistic and utilitarian, to name only a few-in order to uphold the humanistic value of poetry ("poetry as knowledge"). There is, however, a sense that his theoretical consistency derives from a determined refusal to see the blurry borderline between the oppositions. It is more or less easy to point out where Ransom′s theory falters, but more critical efforts should be made to probe into the personal and cultural significance of his persistent dualistic viewpoint. For Ransom the southerner, life demands the precarious balance between the oppositions as the very precondition for its existence and his dualism represents a way to understand man′s fallen state at the realistic level.

• Korean Journal of Health Education and Promotion
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• v.23 no.3
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• pp.99-119
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• 2006

Objectives: This study intends to understand the difference within group of social support level and the effect of social support to health behaviors and health status of the elderly by selecting the old of local society as target. Methods: Data were obtained from self-administered questionnaire of 8,688 persons, older than 65 years, living in a community. We measured the sociodemographic characteristics, social support(family support, other support, quality of support), physical health state(subjective health status, number of chronic disease), physical function state(activities of daily living; ADL, instrumental activities of daily living; IADL), cognition state(mini-mental state examination-Korean; MMSE-K) and depression state(short form of geriatric depression scale; SGDS), health behaviors(smoking, drinking, exercise, eating habit). Univariate, multinominal logistic regression and covariance structure analysis were employed to analyze factors affecting on the social support of the elderly. Results: When considering the degree of social support by the sociodemographic characteristics of the older adults, the family support, other support and quality of support is better when the old is male, young, high education and self-reported living status is good and it has significance statistically. When considering the relation between social support and health status, the family support, other support and quality of support is better when the old's subjective and objective physical health status is good. The family support, other support and quality of support is better when the old's subjective health status is better. The other support and quality of support is better when the old's ADL(activities of daily living) and IADL(instrumental activities of daily living) are good. The family support, other support and quality of support is better when the old's cognitive function and depression state is better. When considering the relation between social support and health behaviors, in case of smoking and drinking, the quality of support, family support and other support is better when the old smokes and drinks rather than the old does not. In case of exercise and eating habit, the family support, other support and quality of support is better when the old exercises and eats regularly rather than the old does not. It has significance statistically. From the result of performing covariance structure analysis by structural equation modeling(SEM) with two endogenous variable(health behaviors and health status) and one exogenous variable(social support), factor loading of health status is 0.74 and factor loading of health behaviors is 0.05. The social support explains health status of 55.4% and health behaviors of 2.9%. Conclusions: This study has the meaning that it finds the difference of social support generating from inside of the group for the old residing in city and country and specifies the effect that the difference of social support influences to health status and health behaviors. From now on, in the development of health improvement strategy of the olds, it is necessary to approach from inclusive aspect while considering psychosocial factor such as social support and social economical factor as well as health status.

• Geomechanics and Engineering
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• v.30 no.6
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• pp.503-515
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• 2022

The permeability coefficient is an essential parameter for the study of seepage flow in fractured rock mass. This paper discusses the feasibility and application value of using readily available RQD (rock quality index) data to estimate mine water inflow and grouting quantity. Firstly, the influence of different fracture frequencies on permeability in a unit area was explored by combining numerical simulation and experiment, and the relationship between fracture frequencies and pressure and flow velocity at the monitoring point in fractured rock mass was obtained. Then, the stochastic function generation program was used to establish the flow analysis model in fractured rock mass to explore the relationship between flow velocity, pressure and analyze the universal law between fracture frequency and permeability. The concepts of fracture width and connectivity are introduced to modify the permeability calculation formula and grouting formula. Finally, based on the on-site grouting water control example, the rock mass quality index is used to estimate the mine water inflow and the grouting quantity. The results show that it is feasible to estimate the fracture frequency and then calculate the permeability coefficient by RQD. The relationship between fracture frequency and RQD is in accordance with exponential function, and the relationship between structure surface frequency and permeability is also in accordance with exponential function. The calculation results are in good agreement with the field monitoring results, which verifies the rationality of the calculation method. The relationship between the rock mass RQD index and the rock mass permeability established in this paper can be used to invert the mechanical parameters of the rock mass or to judge the permeability and safety of the rock mass by using the mechanical parameters of the rock mass, which is of great significance to the prediction of mine water inflow and the safety evaluation of water inrush disaster management.

• International Journal of Control, Automation, and Systems
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• v.4 no.6
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• pp.714-724
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• 2006

In this note a method of designing optimal vibration control based on Haar functions to control of bounce and pitch vibrations in engine-body vibration structure is presented. Utilizing properties of Haar functions, a computational method to find optimal vibration control for the engine-body system is developed. It is shown that the optimal state trajectories and optimal vibration control are calculated approximately by solving only algebraic equations instead of solving the Riccati differential equation. Simulation results are included to demonstrate the validity and applicability of the technique.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.33B no.3
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• pp.9-16
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• 1996

LQ-servo is a robustness guaranteed multivariable controller design method based on the LQR structure to improve command following with output feedback. in this paper we introduce a weighting factor on the low frequency part of the state weighting matrix in the performance index in order to increase the low frequency gain of loop transfer function matrix T(s) in the loop shaping design method.