• Biomolecules & Therapeutics
• /
• v.22 no.5
• /
• pp.453-459
• /
• 2014

Chronic mild stress (CMS) has been reported to induce an anhedonic-like state in mice that resembles some of the symptoms of human depression. In the present study, we used a chronic mild stress animal model of depression and anxiety to examine the responses of two strains of mice that have different behavioral responsiveness. An outbred ICR and an inbred C57BL/6 strain of mice were selected because they are widely used strains in behavioral tests. The results showed that the inbred C57BL/6 and outbred ICR mice were similarly responsive to CMS treatment in sucrose intake test (SIT) and open field test (OFT). However, the two strains showed quite different responses in forced swimming test (FST) and novelty-suppressed feeding (NSF) test after 3 weeks of CMS treatment. Only C57BL/6 mice displayed the depression- and anxiety-like behavioral effects in response to CMS treatment in FST and NSF test. Our results suggest that there are differences in responsiveness to CMS according to the different types of strain of mice and behavioral tests. Therefore, these results provide useful information for the selection of appropriate behavioral methods to test depression- and anxiety-like behaviors using CMS in ICR and C57BL/6 mice.

• Anxiety and mood
• /
• v.2 no.2
• /
• pp.122-127
• /
• 2006

Objective : We examined the putative association between the psychological symptoms and hypoxemia in hospitalized pneumoconiosis patients. Methods : One hundred and nine hospitalized pneumoconiosis patients were divided into two groups according to their level of hypoxemia (PaO2); hypoxemic group consisted of 47 patients with PaO2 lower than 80 mmHg, and comparative group consisted of 62 patients with higher than 80 mmHg. All of them were interviewed with the Hamilton Depression Rating Scale (HAM-D), and completed the Symptom Checklist-90items-Revised (SCL-90-R) and the State-Trait Anxiety Inventory (STAI). The medical data (PaO2, PaCO2, Hb, and Hct), number of hospital days and socio-demographic data as well as scores of the three psychological measurements were compared between the two groups. Results : Hypoxemic patients with lower PaO2 showed higher scores in the HAM-D (p=0.01) and stateanxiety subscale of the STAI (p<0.05). Values of hemoglobin and hematocrit were negatively correlated with levels of trait-anxiety (p<0.05). Thirty patients (27.5%) of total subjects suffered from depression (higher than 18 in the HAM-D), and 46.8% of hypoxemic patients were depressed, whereas 12.9% of comparative group patients were depressed (p=0.01). Conclusion : These results suggest that depression and anxiety might be associated with the hypoxemic mechanism in pneumoconiosis patients.

• Korean Journal of Adult Nursing
• /
• v.12 no.3
• /
• pp.407-417
• /
• 2000

The purpose of this study was to examine the effect of preoperative teaching as a nursing intervention on the emotional status of the patients prior to surgery. The method of this study was Nonequivalent Control Group Non-Synchronize Design. The data were selected from H universuty hospital in Seoul, and they consisted of an experimental group-30patients, and a control group-30 patients. The questionnaire consisted of 28 Preoperative Stress Inventory(Kang, 1998), and 16 State- Trait Anxiety Inventory(Spielberger, 1972). The collected data were analized by means of frequency, percentage, $X^2$ test, t-test and paired t-test with SPSS WIN. The results of this study were as follows : 1. The level of stress prior to surgery was significantly lower for the preoperative teaching group than for the control group(t=2.61, p< .01). 2. The level of anxiety prior to surgery was not significantly lower for the preoperative teaching group than for the control group. 3. The difference level of the anxiety level the prior to surgery was significantly higher for the preoperative teaching group than for the control group(t=2.82, p< .01). In conclusion, preoperative teaching is a beneficial nursing intervention that has a positive effect on the stress and anxiety of patients prior to surgery. Therefore it is recommended to use the preoperative teaching program as a nursing intervention for patients prior to surgery.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.19 no.2
• /
• pp.216-229
• /
• 1995

The main purpose of this study was to develop and validate a scale for measuring situation\ulcornerspecific anxiety that consumers experience while shopping for ready\ulcornerto-wear clothes. A 92 five-point items, Likert type scale, entitled the RMCCAS(The Ready\ulcornerMade Clothes Consumer Anxiety Scale) was developed and administered to 354 female college students. Data collected were subjected to a series of statistical analysis: item analysis, factor analysis, estimation of validity and reliability and descriptive statistics. A second-order factor analysis conducted to 15 factors obtained from a first-order factor analysis yieled three factors; Fitness of Fashion and Design to indiviuality and time(scale 1), Reliance on Price and Quality including Suitableness of Material and Color(scale 2), and Practicality in Dressing and Maintaining(scale 3). Obtained concurrent validity of the RMCCAS subscales with the trait anxiety were .056(subscale I), .082(subscale 2), .033(subscale 3), and .050(total scale). that with state anxiety were .421(subscale I), .217(subscale 2), .198 (subscale 3), and .407(total scale); that with the CP AS were. 721(subscale 1), .789(subscale 2), .570(subscale 3), and .841(total scale). All of the obtained coefficients of Cronbach alpha, split\ulcornerhalf reliability, and test-retested reliability over an interval of. 8 weeks were above .80. Besides, descriptive data from the RMCCAS satisfactorily supported conditions required for the normal distribution of obtained scores. In conclusion, a close exa:nination of validity, reliability, and descriptive statistics of the RMCCAS indicates that three subscales including the scale have a resonable scaling-prop\ulcornererties. Further research is suggested for obtaining norms for more representative target samples and for tapping the possibility of using subsea Ie 2 as a unidimensional measure .

• Journal of Korean Biological Nursing Science
• /
• v.18 no.3
• /
• pp.127-134
• /
• 2016

Purpose: The purpose of this study was to investigate the physiological index, anxiety and depression by the severity of lower urinary tract symptoms in patients with benign prostatic hyperplasia. Methods: This research was conducted from the 4th to the 27th of May in 2016 on112 patients with benign prostatic hyperplasia. The data were analyzed using a chi-square test, ANOVA, and Pearson Correlation Coefficients. Results: The results demonstrated a difference depending on the dysuria period of each lower urinary tract symptom, marital status, occupation and perceived health state of the patient. The physiological index by lower urinary tract symptoms showed a difference in the maximum flow rate, amount of post-void residual urine and Prostate-Specific Antigen (PSA), and anxiety and depression factors also revealed a difference. Lower urinary tract symptoms showed a positive correlation to the amount of post voided residual urine and PSA, a negative correlation to the maximum flow rate and also indicated a positive correlation to depression. Conclusion: The results of the study belonging to the moderate and severe categories were high when the result was based on the categorization of subjects with benign prostatic hyperplasia with lower urinary tract symptoms. Considering that depression levels increase as the symptom intensifies and the anxiety score is also high with mild symptoms, psychological support intervention is needed when a pattern of benign prostatic hyperplasia appears.

• Journal of Korean Academy of Nursing
• /
• v.4 no.2
• /
• pp.44-56
• /
• 1974

Very few studies regarding the effects of preoperative nursing intervention on children's welfare after surgery have been conducted. The purpose of this study was 1) to evaluate the effects of preoperative nursing instructions on children's physical recovery and emotional state after surgery and 2) to analyse the relationship between the effects of preoperative nursing instructions and the age and general anxiety of child. The study was conducted flow: August 15th to October 30th at Severance Hospital, Seoul, Korea. A total of 41 Pediatric surgical Patients, between the age of 4 to 14, participated in the study. Twenty patients, randomly selected, were visited by the experimenter in the evening before, surgery and received specific preoperative nursing instructions. These instructions were designed to alleviate emotional stress and were adopted to the age of child. The postoperative recovery of these patients were then compared with a randomly selected control group of 21 patients who received only the routine preoperative care by the staff in the hospital Dependent variable were vomiting, pain medication, ability to void, elevation of temperature, infection, the between surgery and hospital discharge and postoperative emotional stress which was measured by the vital signs. Because of the limitation of the sample size it was difficult to obtain valid statistical results. However, the analysis of the raw data indicates that: 1) the preoperative nursing instructions appears to promote physical recovery and it seems especially effective in preventing elevation of temperature and shortening the length of the hospital stay, 2) the preoperative nursing instruction also seems to be effective in relieving the child's emotional stress(situational anxiety) after surgery, 3) the patient's general anxiety level preparatively seems to be a predictor of postoperative problems, 4) the preoperative nursing instructions were an effective means of promoting physical recovery in every age group as long as the child understood the instructions. The above data would seem to indicate that all preoperative pediatric patients four years of age or older, if they can understand, should have preoperative nursing instruction in order to alleviate postoperative stress and enhance physical recovery. The level of general anxiety preparatively deserves special attention since the amount of nursing instruction needed seems to vary with tile level of anxiety.

• The Journal of the Korean dental association
• /
• v.49 no.2
• /
• pp.95-103
• /
• 2011

Purpose : The purpose of this study was to identify and assess factors that may contribute to pain of patients undergoing implant surgery. Materials and Methods: A total of 24 patients who underwent implant surgery were included in the study. Each patient's anxiety was measured using Corah's dental anxiety score(DAS) and modified Spielberger's state-trait anxiety inventory(STAI) immediately after the operation. Also, level of pain was measured using visual analog scale(VAS) during the operation and 48 hours after the surgery. The effect of various factors, such as demographic variables, previous dental experiences and operation time were also analyzed. Results: Postoperative pain levels were relatively low than expected. However, DAS and STAI were high among patients, and it showed that patients had anxieties about implant surgery according to DAS and STAI values. The previous dental experience did not affect the pain level, but the duration of surgery and the presence of accompanied advanced surgery did. Conclusion: To reduce patient's pain, proper management of anxiety will be required and careful attention is needed when performing local infiltration.

• Korean Journal of Psychosomatic Medicine
• /
• v.14 no.1
• /
• pp.53-61
• /
• 2006

Objectives: This study was designed to evaluate difference of the alexithymia between panic patients and normal controls by examination of the relationships between different components of the alexithymia construct and level of anxiety and depression in panic patients and normal controls. Methods The subjects were 167 patients who met DSM-IV criteria for panic disorder and 110 normal controls. They drew up symptom checklists and self-rating scales, and were measured by Anxiety Disorders Interview Schedule-Panic attack & Agoraphobia(ADIS-P & A), Korean version of Toronto Alexithymia Scale (TAS-20K), Spielberger State-Trait Anxiety Inventory-State & Trait (STAI-S & T), Beck Depression Inventory (BDI), and Revised Anxiety Sensitivity Index (ASI-R). For statistical analysis, we performed t-test to compare the sociodemographic characteristics and the scores of self reported scales between panic patients and normal controls. Pearson correlation was performed between TAS-20K and it's subfactors, STAI-S & T, ASI-R and BDI in panic patients and normal controls. And stepwise multiple regression analysis was preformed to explain results of correlation analysis for alexithymia. Results: The panic patients reported more significant alexithymic (p<0.001), more difficulty identifying feeling (p<0.001) and describing feeling (p=0.001) than normal controls. Futhermore, panic patients were more significant anxious, sensitive to anxious feeling and depressive than normal controls. Moreover, the alexithymia of panic patients was explained by trait-anxiety $({\Delta}R^2=0.255)$ and anxiety sensitivity $({\Delta}R^2=0.062)$, that of normal controls was predicted by depression $({\Delta}R^2=0.144)$ and anxiety sensitivity $({\Delta}R^2=0.033)$ Conclusion: The panic patients reported more anxious and sensitive to anxious feeling, and these symptoms predict alexithymia in panic patients. However, the alexithymia of normal controls was explained by depression more than anxiety sensitivity, and such a result isn't consistent with previous studies and this may be mainly due to difference of the homogeneity in object of the studies.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.9 no.1
• /
• pp.54-66
• /
• 1998

Objectives：This study was to investigate the impact of parental psychiatric disorder on offspring's depression, anxiety, self concept, perception of familial relationship compared with offspring of normal control. In offsprings of parents with psychiatric disorder, this study explored whether their psychopathology, self concept, and perception of familial relationship were influenced by parent’s sex, onset time of parent’s psychiatric disorder and parent’s psychiatric diagnosis. Methods：52 offsprings aged 10-18 years of 39 psychiatric outpatient were surveyed from June, 1997 to April, 1998 and completed several questionnaaire, including Korean from of the Family Environment Scale, Korean form of the State-Trait Anxiety Inventory for Children, Korean form of Kovac’s Children’s Depression Inventory, and Korean form of Piers-Harris Children’s Self-Concept Scale. Their score was compared with offsprings’ of normals. In offsprings of parents with psychiatric disorder, they were compared according to parent’s sex, onset time of parent's psychiatric disorder and parent’s psychiatric diagnosis. Results：The results were as follows：1) Offsprings of parents with psychiatric disorder reported higher level of state anxiety and lower level of the FES expressive subscale than offsprings of normals(p<0.05). But they reported higher level of PHCSCS intellectual & school status subscale and popularity subscale than normals(p<0.05). 2) There were no differences in anxiety, depression, self concept, and perception of familial relationship between patient’s sex. 3) Offsprings less than 3 years old when parent’s psychiatric disorder had developed showed higher level of trait anxiety and lower level of FES control subscale than offsprings more than 3 years old (p<0.05). 4) There were no diferences in anxiety, depression, self concept, and perception of familial relationship between patient’ diagnostic groups(schizophrenia spectrum disorder-mood disoderneurosis). Conclusion：The finding indicated that self reported scale of anxiety and depression showed no significant difference between offsprings of psychiatric patients and offsprings of normals. In offsprings of parents with psychiatric disorder, parent’s sex and psychiatiric diagnosis had no influence on offspring’s psychopathology. But the offspring’s age(before 3 years old) when the parent’s psychiatriric disorder developed had influence on higher level of offspring’s trait anxiety. For further high risk group study, direct interview and evaluation of parent-child agreement or teacher-child agreement will be needed in longitudinal study.

• The Journal of the Korea Contents Association
• /
• v.15 no.4
• /
• pp.545-555
• /
• 2015

We investigated the influence of negative emotion such as state-trait anxiety and depression and working memory (WM) on Foreign Language Vocabulary Learning (FLVL) of South Korean university students. Also, its implications for developing contents for FLVL were discerned. To do so, state-trait anxiety and depression inventories as well as four kinds of WM test were performed for 132 undergraduate students. Participants also had two semantic learning sessions for Swahili words. The mean scores of negative emotions were normal level. The results of structural equation modeling (SEM) showed that there was no effect of negative emotion on FLVL, while direct effects of the negative emotion on WM and the WM on FLVL were significant. Such results suggested that FLVL would be weakened, with the result that WM had been impaired by negative emotions. These outcomes suggested that when developing FLVL content for university students, it is necessary to consider the negative emotions of foreign language learners and to develop the contents for FLVL in the light of WM load.