• Journal of Periodontal and Implant Science
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• 제30권2호
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• pp.429-442
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• 2000

Based on current evidence in the literature, it is known that endotoxin is a weakly adherent surface phenomenon and that power-driven instruments can be used to accomplish definitive root detoxification and maximal wound healing without overinstrumentation of root and without extensive cementum removal. And one of the newly developed curette tips used with low power of piezoelectric ultrasonic scaler, is effective to remove calculus and not to remove the excessive cementum. The purpose of this study is therefore, to assess the influence of ultrasonic power and various working parameters on root substitute removal when instrumentation is performed with the curette tip on piezoelectric ultrasonic scaler. This study assessed defect depth, width and area resulting from instrumentation using a piezoelectric ultrasonic scaler with a curette type tip in vitro to acrylic resin block as a root substitute. The working parameters was standardized by the sledge device which controls lateral force(0.5 N, 1 N, 2 N) and instrumentation time(5 sec, 10 sec, 20 sec) and power setting was adjusted 0,2,4,8 in P mode. Power setting had the greatest influence on defect depth compared to lateral force and instrumentation time(standardized regression parameter estimates${\pm}$standard error, $0.37{\pm}0.02$, $0.19{\pm}0.02$, $0.07{\pm}0.02$). The effects on defect area also greatest for power setting($0.57{\pm}0.03$) compared to lateral force and instrumentation time($0.33{\pm}0.03$, $0.12{\pm}0.03$). The effect of the power setting on the defect width($0.15{\pm}0.01$) is not so great as defect depth or defect area compared to lateral force($0.12{\pm}0.01$) and effect of instrumentation time is minimal($0.02{\pm}0.01$). It could be concluded that the power setting has the greatest influence on the defect depth and area in curette type tip with low power of piezoelectric ultrasonic device. Many parameters can be adjusted in various situation in clinical use of piezoelectric ultrasonic scaler but the power setting is the first parameter to be adjusted.

• Bulletin of the Korean Chemical Society
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• 제33권1호
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• pp.177-182
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• 2012

A new composition of standardized Scutellariae Radix extract (HPO12) was developed for treatment of Alzheimer's disease. For the preclinical pharmacokinetic study of HPO12, a rapid, sensitive, and selective LCMS/MS method was developed and validated for the simultaneous determination of 4 bioactive compounds, baicalein, baicalin, wogonin, and wogonoside. After extraction with ethylacetate, chromatographic analysis was performed on a Thermo $C_{18}$ column ($150mm{\times}2.1mm$, $3{\mu}m$) with a mobile phase consisting of 0.1% formic acid (A) and 0.1% formic acid in 95% acetonitrile (B) by using gradient elution at a flow rate of $250{\mu}L/min$. Analytes introduced to a mass spectrometer were monitored by multiple reaction monitoring (MRM) in positive ion mode. Using $25{\mu}L$ of plasma sample, the method was validated over the following concentration ranges: 25-5000 ng/mL for baicalein, 20-40000 ng/mL for baicalin, 1-1000 ng/mL for wogonin, and 5-10000 ng/mL for wogonoside. The intra- and inter-day precision and accuracy of the quality control samples at the 4 concentrations showed $\leq$ 13.7% relative standard deviation (RSD) and 86.6-105.5% accuracy. The method was successfully applied to determine the concentrations of baicalein, baicalin, wogonin, and wogonoside in rat plasma after intraperitoneal and oral administrations of HPO12.

• 한국농공학회논문집
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• 제59권3호
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• pp.29-39
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• 2017

In this study, the GPM (Global Precipitation Mission) IMERG (Integrated Multi-satellitE retrievals for GPM) rainfall data was verified and evaluated using ground AWS (Automated Weather Station) and radar in order to investigate the availability of GPM IMERG rainfall data. The SPI (Standardized Precipitation Index) was calculated based on the GPM IMERG data and also compared with the results obtained from the ground observation data for the Hoengseong Dam and Yongdam Dam areas. For the radar data, 1.5 km CAPPI rainfall data with a resolution of 10 km and 30 minutes was generated by applying the Z-R relationship ($Z=200R^{1.6}$) and used for accuracy verification. In order to calculate the SPI, PERSIANN_CDR and TRMM 3B42 were used for the period prior to the GPM IMERG data availability range. As a result of latency verification, it was confirmed that the performance is relatively higher than that of the early run mode in the late run mode. The GPM IMERG rainfall data has a high accuracy for 20 mm/h or more rainfall as a result of the comparison with the ground rainfall data. The analysis of the time scale of the SPI based on GPM IMERG and changes in normal annual precipitation adequately showed the effect of short term rainfall cases on local drought relief. In addition, the correlation coefficient and the determination coefficient were 0.83, 0.914, 0.689 and 0.835, respectively, between the SPI based GPM IMERG and the ground observation data. Therefore, it can be used as a predictive factor through the time series prediction model. We confirmed the hydrological utilization and the possibility of real time drought monitoring using SPI based on GPM IMERG rainfall, even though results presented in this study were limited to some rainfall cases.

• Journal of Veterinary Science
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• 제21권3호
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• pp.21.1-21.14
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• 2020

Background: Physical exercise is known to cause significant joint changes. Thus, monitoring joint behavior of athletic horses is essential in early disorders recognition, allowing the proper management. Objectives: The aims of this study were to determine the morphological patterns, physical examination characteristics and ultrasound findings of show jumping horses in training and to establish a score-based examination model for physical and ultrasound follow-ups of metacarpophalangeal joint changes in these animals. Methods: A total of 52 metacarpophalangeal joints from 26 horses who were initially in the taming stage were evaluated, and the horses' athletic progression was monitored. The horses were evaluated by a physical examination and by B-mode and Doppler-mode ultrasound examinations, starting at time zero (T0), which occurred concomitantly with the beginning of training, and every 3 months thereafter for a follow-up period of 18 months. Results: The standardized examination model revealed an increase in the maximum joint flexion angles and higher scores on the physical and ultrasound examinations after scoring was performed by predefined assessment tools, especially between 3 and 6 months of evaluation, which was immediately after the horses started more intense training. The lameness score and the ultrasound examination score were slightly higher at the end of the study. Conclusions: The observed results were probably caused by the implementation of a training regimen and joint adaptation to physical conditioning. The joints most likely undergo a pre-osteoarthritic period due to work overload, which can manifest in a consistent or adaptive manner, as observed during this study. Thus, continuous monitoring of young athlete horses by physical and ultrasound examinations that can be scored is essential.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2011년도 학술발표회
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• pp.20-20
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• 2011

The purpose of this research aims to evaluate the emergence of new business mode in the Chinese water market since the mid-2000s - Transfer-Operate-Transfer(TOT) Projects. The study pays special attention to the case of the Hefei Wangxiaoying Wastewater Treatment TOT Project, which was awarded to the consortium of Berlin Water International and its Chinese partner in late 2004. The consortium secured an exclusive operating right for 23 years on the basis of a TOT scheme and would take responsibility of all the profits and losses in the operation of the plant. The total investment for the transfer amounted to RMB 491 million(US$70 million). The price was more than 288% of the original value, RMB 170 million (US$24 million). The project can be regarded as a successful case because of the following three causes. First, the Hefei government followed a series of standardized procedures in the international bidding, which ignited best-performed international players' competition for the project. Second, the project will bring in cutting-edge operation skills and management know-how. Third, the government succeeded in raising public asset values, and thanks to this, the government is able to consider other similar projects not only in the water sector but also other sectors in public utility services. Nevertheless, Berlin Water's point of view, there are several challenges. First, the company took a risk to pay such a large amount of cash to the Hefei government. Although such premium can be recouped in the operation period of 23 years, whether or not the company would be able to recover the initial investment and realize profits is in question due to an uncertainty of socio-political circumstances in China. Second, Berlin Water should expect a steep rise of water tariffs over the contract period in order to get the investment back. Water pricing is still a sensible matter to Chinese authorities, and therefore, it is uncertain if such rise of water tariffs would be possible. Third, the TOT mode leads to creation of a large amount of cash to government officials, which might have caused corruption between those who are involved in TOT deals. Then, the final contract fee would soar, which often results in the burden of normal customers. As discussed, the TOT mode has drawn much attention of foreign investors as a new alternative to enter into the Chinese water market. But it is important to note that foreign investors should be aware of possible risks in water TOT projects, which reflects some features of the Chinese political economy landscape and social norms. The Hefei case indicates that benefits can overshadow risks in TOT projects, which will continue to attract foreign investors that are dedicated to establishing their strongholds in the Chinese water market.

• 셀메드
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• 제4권1호
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• pp.7.1-7.8
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• 2014

Metabolic effects of ten daily doses of standardized extract of Andrographis paniculata leaves (AP) rich in andrographolide were evaluated in a rat model of type-2 diabetes and in diet induced obese rats. AP was administered per-orally as suspension in 0.3% carboxymethylcellulose at doses of 50, 100 and 200 mg/kg/day for 10 consecutive days. Blood glucose, insulin and lipid profile of rats were measured by using enzyme kits. In addition, effects of such treatments on anti-oxidant enzymes activity and histopathological changes in various organs of diabetic rats were assessed. AP treatments reversed body weight losses and increased plasma insulin level in diabetic rats. The anti-oxidant enzymes activity became normal and histopathological changes observed in pancreas, liver, kidney and spleen of diabetic animals were less severe in extract treated groups. On the other hand, hyperinsulinemia and increased body weight gains observed in high fat or fructose fed rats were less severe in the extract treated groups. These observations revealed therapeutic potentials of the extract for treatments of diabesity associated metabolic disorders, and suggest that the effects of the extract on insulin homeostasis depend on the metabolic status of animals. Activation of cytoprotective mechanisms could be involved in its mode of action.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 추계학술대회논문집
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• pp.17-20
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• 2006

Korean traditional houses have been developed in sympathy with natural environment and formed comfortable indoor condition by properly using surrounding natural resources including building layout, space construction and material our traditional wooden windows adjusting ambient temperature and humidity have both the functions of window and door, although they are clearly divided in the West. While window paper is attached from the outside in China and Japan, it is attached from the inside in Korea. The opening and closing mode of windows is similar and their dimensions are shown not to he standardized but diverse in terms of the characteristic of wooden furniture and that of components placed between columns. Thus this study is to look into the performance of band-lattice door of a typical traditional one by observing changes in sound absorption characteristics according to difference in thickness and finishing method of window paper and those in sound absorption characteristics with the changed thickness of air layer in traditional windows and doors.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 춘계학술대회논문집
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• pp.1147-1150
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• 2007

Korean traditional houses have been developed in sympathy with natural environment and formed comfortable indoor condition by properly using surrounding natural resources including building layout, space construction and material. Or traditional wooden windows adjusting ambient temperature and humidity have both the functions of window and door, although they are clearly divided in the West. While window paper is attached from the outside in China and Japan, it is attached from the inside in Korea. The opening and closing mode of windows is similar and their dimensions are shown not to be standardized but diverse in terms of the characteristic of wooden furniture and that of components placed between columns. Thus this study is to look into the performance of band-lattice door of a typical traditional one by observing changes in sound insulation characteristics according to difference in thickness and finishing method of window paper and those in sound insulation characteristics with the changed thickness of air layer in traditional windows and doors.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 춘계학술대회논문집
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• pp.964-968
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• 2007

The measurement of floor impact sound have been standardized in KS 2810-1 and 2. The height of receiving microphones position is specified in the standard as 1.2m which is almost half height of apartment rooms as a listening position. In this study, receiving positions are investigated by measuring the distribution of sound pressure levels at 792 receiving microphone positions in the standard testing building. Standard impact sources, tapping machine and impact ball, are driven on the center position in the source room where is located at the above floor. It was found that the distribution of sound pressure levels in the receiving room indicates significant deviation at different frequencies there is more than 5dB drop at 63Hz but 2dB rise at 125Hz at a height of 1.2m when the impact ball is driven, in the other case of a generating tapping machine there is more than 2dB rise at 125Hz at a height of 1.2m due to room modes.

• 한국신뢰성학회지:신뢰성응용연구
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• 제11권2호
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• pp.111-126
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• 2011

The clutch coil mounted on the automotive air conditioner is an important part which actuates the clutch to connect or disconnect the pulley and the compressor according to the climate control condition in an automobile. Here, it is generally required that the clutch coil should ensure the long term durability requirement, such as a warranty for the 10 years of field operation or 160,000 km driving, especially in a brand new item, and so forth. However, some difficulties have arisen in restoring its credibility, since domestic specifications for the part have not been yet unified. In order to ensure the reliability, test methods and assessment criteria should be standardized. Moreover, assessed lifetime under specific conditions and potential failure analysis would be important. In this study, lifetime test specifications for the clutch coil have been reviewed and methodological suggestions are provided to ensure reliability, utilizing a quality function deployment through the potential failure mode effect analysis.