• Journal of Korean Neurosurgical Society
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• v.39 no.2
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• pp.130-135
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• 2006

Objective : After ischemic stroke, partial recovery of function frequently occurs and may depend on the plasticity of axonal connections. Here, we examine whether blockade of the Nogo/NogoReceptor[NgR] pathway might enhance axonal sprouting and thereby recovery after focal brain infarction. Methods : Adult male Sprague Dawley rats weighing $250{\sim}350g$ were used. Left middle cerebral artery occlusion[MCAO] was induced with a intraluminal filament. An osmotic mini pump [Alzet 2ML4, Alza Scientific Products, Palo Alto, CA] for the infusion of NgR-Ecto[310]-Fc to block Nogo/NgR pathway was implanted 1 week after cerebral ischemia. Prior to induction of ischemia, all animals received training in the staircase and rotarod test. Two weeks after biotin dextran amine injection, animals were perfused transcardially with PBS, followed by 4% paraformadehyde/PBS solution. Brain and cervical spinal cord were dissected. Eight coronal sections spaced at 1mm intervals throughout the forebrain of each animal with cresyl violet acetate for determination of infarction size. Images of each section were digitized and the infarct area per section was measured with image analysis software. Results : Histological examination at 11 weeks post-MCAO demonstrates reproducible stroke lesions and no significant difference in the size of the stroke between the NgR[310]Ecto-Fc protein treated group and the control group. Behavioral recovery is significantly better and more rapid in the NgR-Ecto[310]-Fe treated group. Blockade of NgR enhances axonal sprouting from the uninjured cerebral cortex and improves the return of motor task performance. Conclusion : Pharmacological interruption of NgR allows a greater degree of axonal plasticity in response this is associated with improved functional recovery of complicated motor tasks.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.7
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• pp.1687-1693
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• 2013

This paper addresses an adaptive postprocessing technique to remove blocking effects of the highly compressed images. The proposed technique removes blocking effects selectively by applying filters with different strength according to block analysis based on the directional activity. One-dimensional filters which are used to remove grid noises accomplish the adaptive filtering to the signal itself as well as to the directionality of the block. Moreover, we propose a detection method of the staircase noises and corner outliers and a two-dimensional directional filter to remove them. Experimental results for various images and bitrates show that the proposed method outperforms the conventional methods in PSNR for the objective performance and GBIM for the subjective quality evaluation.

• Journal of the Korean Society for Railway
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• v.17 no.2
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• pp.87-93
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• 2014

The KTX, running in Korea but imported from Alstom Co. in France, has folding type staircases complying with European standard EN 4752. However, when operating, the step size is only 200mm, while the Korean standard step size is 253mm, a standard reflecting the average value of persons aged 20~60. From the aspect of kinesiology, the current step size can cause falls or slips during embarking and disembarking of passengers because body load is mostly focused on the heel and the current step is much more narrow than the standard size. Thus, we have performed an analytical study to check the safety of folding type staircases on the KTX after re-design.

• International Journal of Naval Architecture and Ocean Engineering
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• v.8 no.4
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• pp.301-311
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• 2016

This paper describes the whole procedures to determine ice-induced global loads on the ship using measured full-scale data in accordance with the method proposed by the Canadian Hydraulics Centre of the National Research Council of Canada. Ship motions of 6 degrees of freedom (dof) are found by processing the commercial sensor signals named Motion Pak II under the assumption of rigid body motion. Linear accelerations as well as angular rates were measured by Motion Pak II data. To eliminate the noise of the measured data and the staircase signals due to the resolution of the sensor, a band pass filter that passes frequencies between 0.001 and 0.6 Hz and cubic spline interpolation resampling had been applied. 6 dof motions were computed by the integrating and/or differentiating the filtered signals. Added mass and damping force of the ship had been computed by the 3-dimensional panel method under the assumption of zero frequency. Once the coefficients of hydrodynamic and hydrostatic data as well as all the 6 dof motion data had been obtained, global ice loads can be computed by solving the fully coupled 6 dof equations of motion. Full-scale data were acquired while the ARAON rammed old ice floes in the high Arctic. Estimated ice impact forces for two representative events showed 7e15 MN when ship operated in heavy ice conditions.

• The Journal of Sustainable Design and Educational Environment Research
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• v.15 no.3
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• pp.15-25
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• 2016

The purpose of this study is to reveal the process of forming a community in the school and to present the basic data necessary for the establishment of a social sustainable environment and space for future school space. In addition to a new awareness of time, it was carried out to help students understand the community forming space in the school. The purpose of this study was to investigate the formation process and characteristics of resting time community in the school. As a result of the analysis on the formation of community space in the school, there were many opinions that community space for social communication and interaction promotion in school is all without difference by gender and grade, and as a space which is considered to be most suitable as community space. A hallway alcove space, a small space adjacent to the classroom, and a multipurpose staircase. In addition, students wanted to make the communication activities such as meeting, communication, relaxation, and social exchange into the hall and corridor space in the corridor as the most desirable community space.

• Journal of the Korea Society of Computer and Information
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• v.17 no.12
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• pp.49-60
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• 2012

In this paper, we propose a hardware design for correction of barrel distortion using the nearest coordinates in the corrected image. Because it applies the nearest distance on corrected image rather than adjacent distance on distorted image, the picture quality is improved by the image whole area, solve the staircase phenomenon in the exterior area. But, because of additional arithmetic operation using design of bilinear interpolation, required arithmetic operation is increased. Look up table(LUT) structure is proposed in order to solve this, coordinate rotation digital computer(CORDIC) algorithm is applied. The results of the synthesis using Design compiler, the design of implementing all processes of the interpolation method with the hardware is higher than the previous design about the throughput, In case of the rear camera, the design of using LUT and hardware together can reduce the size than the design of implementing all processes with the hardware.

• Journal of the Korea Convergence Society
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• v.11 no.3
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• pp.19-26
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• 2020

In this paper, we propose a method to analyze the loss region of the dictionary-based super resolution result learned for image quality improvement and to map the learning data according to the analyzed loss region. In the conventional learned dictionary-based method, a result different from the feature configuration of the input image may be generated according to the learning image, and an unintended artifact may occur. The proposed method estimate loss information of low resolution images by analyzing the reconstructed contents to reduce inconsistent feature composition and unintended artifacts in the example-based super resolution process. By mapping the training data according to the final interpolation feature map, which improves the noise and pixel imbalance of the estimated loss information using a Gaussian-based kernel, it generates super resolution with improved noise, artifacts, and staircase compared to the existing super resolution. For the evaluation, the results of the existing super resolution generation algorithms and the proposed method are compared with the high-definition image, which is 4% better in the PSNR (Peak Signal to Noise Ratio) and 3% in the SSIM (Structural SIMilarity Index).

• The Korean Journal of Pain
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• v.21 no.2
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• pp.126-130
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• 2008

Background: Females generally have a lower pain and temporal summation threshold than men. However, the results of studies designed to evaluate gender differences in the thresholds of heat pain and the temporal summation have been inconsistent. Newly developed device, CHEPS (Contact Heat Evoked Potential Stimulation) model of PATHWAY, have superiority on its fast rise and return time in temperature. Therefore we investigated gender differences in heat pain and temporal summation threshold. Methods: Forty healthy volunteers (20 males and 20 females) were enrolled in this study. A thermode was applied to the volar side of each volunteer's left forearm and heat pain and the temporal summation threshold was then measured. The heat pain threshold was estimated using the staircase method by starting from $36^{\circ}C$ and then increasing the temperature in $0.5^{\circ}C$ increments. The temporal summation threshold was estimated by applying five successive stimulation of the same temperature starting at $2^{\circ}C$ lower than the heat pain threshold and then increasing the temperature in $0.5^{\circ}C$ increments. Results: The mean heat pain thresholds was found to be $41.63{\pm}1.63^{\circ}C$ for males and $41.60{\pm}1.84^{\circ}C$ for females and the temporal summation thresholds were found to be $40.83{\pm}1.64^{\circ}C$ for males and $40.77{\pm}1.93^{\circ}C$ for females. The differences between males and females were not statistically significant. Conclusions: The result of this study suggested that there are no gender differences in heat pain and temporal summation threshold.

• Nuclear Engineering and Technology
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• v.21 no.1
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• pp.1-11
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• 1989

Numerous losses of decay heat removal capability have occurred at U during stutodwn while its significance to safety is needless to say. A study is carried out as an attempt to assess what could be done to lower the frequency of these events and to mitigate their consequences in the unlikely event that one occurs. The shutdown risk model is developed and analyzed using Event/Fault Tree for the typical pressurized water reactor. The human cognitive reliability (HCR) model, two-stage bayesian approach and staircase function model are used to estimate human reliability, initiating event frequency and offsite power non-recovery probability given loss of offsite power, respectively. The results of this study indicate that the risk of a Pm at shutdown is not much lower than the risk when the plant is operating. By examining the dominant accident sequences obtained, several design deficiencies are identified and it is found that some proposed changes lead to significant reduction in core damage frequency due to loss of cooling events.

• Structural Engineering and Mechanics
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• v.72 no.2
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• pp.245-256
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• 2019

The experimentally determined mechanical behavior of the material under the prescribed service conditions is the basis of advanced engineering optimum design. To allow experimental data on the behavior of the material considered, uniaxial stress tests were made. The aforementioned tests have enabled the determination of mechanical properties of material at different temperatures, then, the material's resistance to creep at various temperatures and stress levels, and finally, insight into the uniaxial high cyclic fatigue of the material under different applied stresses for prescribed stress ratio. Based on fatigue tests, using modified staircase method, fatigue limit was determined. All these data contributes the reliability of the use of material in mechanical structures. Data representing mechanical properties are shown in the form of engineering stress-strain diagrams; creep behavior is displayed in the form of creep curves while fatigue of the material is presented in the form of S-N (maximum applied stress versus number of the cycles to failure) curve. Material under consideration was 18CrNi8 (1.5920) steel. Ultimate tensile strength and yield strength at room temperature and at temperature of $600^{\circ}C$: [${\sigma}_{m,20/600}=(613/156)MPa$; ${\sigma}_{0.2,20/600}=(458/141)MPa$], as well as endurance (fatigue) limit at room temperature and stress ratio of R = -1 : (${\sigma}_{f,20,R=-1}=285.1MPa$).