• 동의신경정신과학회지
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• 제15권2호
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• pp.211-219
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• 2004

상기 환자는 $4{\sim}5$년 발한 공황장애로 로컬 정신과에서 1년간 po. med 하시다 별무 호전하시고, 입원 3일전 증세 심하여 본원의 한방치료를 받은 환자로, DSM-4에 의거하면 광장공포증을 동반한 공황장애 환자로 한방적으로는 신음양구허(腎陰陽俱虛)에 간울화화(肝鬱化火)를 겸하였다고 하겠다. 지원탕(志遠湯)을 투여하고, 변증에 따라 자침하며, 주관법(走罐法)을 시행하고, 더불어 인지행동치료를 병행하여 PDSS상 21점이 13점으로 감소하는 좋은 결과를 내어 이를 보고하는 바이다. 하지만 관찰 기간이 그리 길지 않았고, 한방치료와 인지행동치료를 함께 시행함으로써 이상의 치료들 중 어떤 치료가 어느 정도의 효과를 내었는지 그 정도를 측정할 수 없으며, 측정절차도 환자의 주관적인 증상의 호소에 의존하여 객관성이 다소 결여되었다. 이를 보완하기 위해 공황장애에 대한 한방치료, 인지행동치료, 그리고 두 가지를 병행한 치료를 각각 시행한 후 효과를 후위분석연구를 통해 검증한다면 한방치료와 인지행동치료가 각각 어느 부분에 어느 정도의 치료효과를 발생시켰는지 검증할 수 있을 것이다. 이를 위한 향후 객관적이고 지속적인 연구가 필요하리라 사료된다.

• 동의생리병리학회지
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• 제30권1호
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• pp.54-60
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• 2016

Amomum cadamomum Linne (ACL) has long been utilized against the inhibited qi movement related diseases such as dyspepsia, acute gastroenteritis, vomiting and diarrhea in Korean medicine. We speculated that ACL could improve the metabolic disorders such as obesity and type 2 diabetes through removing the phlegm-dampness and promoting the qi movement or stagnation. This study was designed to investigate effects and molecular mechanisms of ACL extract on the improvement of adipocyte dysfunction induced by TNF-α in 3T3-L1 adipocytes. Potential roles of ACL extract in the lipogenesis, inhibition of inflammatory cytokines and insulin resistance, were investigated in this study. Also, we examined the adipose genes and signaling molecules related to insulin resistance and glucose uptake to elucidate its mechanism. Our data demonstrated that TNF-α significantly incresed the release of lipid droplets and the production of MCP-1 and IL-6 from adipocytes. In gene expression, TNF-α reduced the expression of aP2, PPARγ, C/EBPα, GLUT4, and IRS-1 related to lipogenesis and insulin sesitivity, while TNF-α increased the expression of MCP-1 related to inflammation. In addition, TNF-α down-regulated the PPARγ and IRS-1 protein and up-regulated the IRS-1 Ser307 phosphorylation. These alterations induced by TNF-α were prevented by the treatment of ACL extract. Thus, our results indicate that ACL extract can be used to prevent from the TNF-α-induced adipocyte dysfunction through insulin and PPARγ pathways.

• 동의생리병리학회지
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• 제29권5호
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• pp.434-442
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• 2015

The purpose of this review was to survey the Korean Medicine related papers about women with primary dysmenorrhea in order to develop the clinical protocol of the diagnostic medical device. We searched the literature from 2000 through April 2015 using 5 online databases including Oriental Medicine Advanced Searching Integrated Sysptem (OASIS), Research Information Sharing Service (RISS), DataBase Periodical Information Academic (DBpia) and Korean Medical Database (KMBase). We selected papers to meet the following inclusion criteria: the papers involved dysmenorrhea (excluding secondary dysmenorrhea), published papers (excluding textbook, educational materials, conferences, etc.) and the papers matched search keywords or scope, but excluded papers to meet the following exclusion criteria: the duplicative papers, get out of the keywords and scope and not in english or korean language. Finally we found 17 papers and classified the papers according to the three search purposes which were diagnostic tools for evaluating the menstrual pain, dysmenorrhea' pattern identification and menstrual phase. Out of the 16 studies, 4 studies were focused on the diagnostic tools including Visual Analogue Scale (VAS), Measurement of Menstrual Pain (MMP) and etc. Other 5 studies were aimed at menstrual phase, and the other 7 studies were studied for pattern identification. The VAS has been widely used in research and in clinical practice for the detection of the menstrual pain. Treatments for patients with primary dysmenorrhea can be prescribed in consideration of their patterns of sasang constitution or body constitution as following: Qi stagnation-Blood deficiency, cold dampness, Qi deficiency-blood deficiency and liver-kidney deficiency etc. This results of research will be used as a useful material during plan a clinical study of primary dysmenorrhea and acquisition of good clinical data.

• 항공우주기술
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• 제11권1호
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• pp.68-77
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• 2012

공기를 이용한 축소형 4 노즐 클러스터드 엔진 저부 유동에 대한 CFD 해석을 수행하여 수치 방법에 대한 비교와 저부 유동을 분석하였다. 해석결과 Roe나 AUSM의 공간 차분법에 따른 차이는 없었으며, Spalart-Allmaras 1 방정식 난류 모델이 SST k-${\omega}$ 모델이나 k-${\varepsilon}$ 모델에 비하여 본 연구에 비교적 적합한 것으로 나타났다. 클러스터드 엔진 저부 영역은 팽창된 노즐 플룸이 서로 만나면서 고압의 정체 영역을 일부 형성하며, 일부의 플룸이 저부 방향으로 역류 팽창하는 것이 관측된다. 저부로 팽창된 플룸은 노즐과 노즐 사이의 최소 공간으로 정의되는 "최소 배출면"을 통해 외기로 빠져 나가는 데 저부면에 가까울수록 더욱 빠른 속도로 빠져나가고 경험적 이론과 다르게 노즐과 노즐 사이의 공간 전체가 유동의 목을 형성하는 것이 아닌 것으로 확인된다. 또한 노즐 벽면 온도가 역류 플룸의 온도에 큰 영향을 끼치는 것을 확인하였다.

• 한국전산유체공학회지
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• 제20권4호
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• pp.70-80
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• 2015

Construction waste is known to include a large part of coarse and fine aggregates, which can be recirculated in the industry. Separating those aggregates economically from the waste has been thus considered to be one of the most important issues in this field. In particular, paste mixed in the waste causes significant complain from the inhabitants living near the place where waste-processing equipments are built and operated. In this study, we investigate the operational principle of a newly developed paste separator by using theoretical (in this first part) and CFD (in the second part) analysis. The separator consists of a rotor which turned out to play a significant role in separating those pastes from the aggregates. Under suitable assumptions regarding the air flow velocity as well as the particle velocity, we show that particles can be stagnant at the outlet of the roto channel for a wide range of parameter values, which allow the particles to get enough time to settle down via the gravitation. We also demonstrate such phenomenon by using a simple numerical simulation.

• 대한토목학회논문집
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• 제12권2호
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• pp.285-291
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• 1992

본 연구는 사여과지(砂濾過池)에 대한 여과저항이론(濾過抵抗理論)을 기초로 하여 폭기생물막(曝氣生物膜) 여과지(濾過池)의 여과저항이론을 구명(究明)하는 것이다. 여과저항(濾過抵抗)에 크게 영향을 미치는 인자로는 사여과지의 경우 주로 현탁성 부유물질인 반면에 폭기생물막 여과지의 경우는 여층(濾層)내의 여재(濾材)표면에 부착된 미생물막(微生物膜)의 증식(增殖)과 SS성분의 부착 그리고 상승하는 기포(氣泡)의 정체 등이 여충내의 여재간극(濾材間隙)을 폐새(閉塞)시킴으로서 여과저항(濾過抵抗)을 발생시킨다. 이러한 영향 인자들은 사여과저항(砂濾過抵抗) 이론(理論)에 접목시킨 결과 폭기생물막(曝氣生物膜) 이론식(理論式)을 도출할 수 있었다. 따라서 본 연구에서 제안된 폭기생물막 여과저항 이론식을 pilot plant를 통한 수처리실험(水處理實驗) 결과 이론치와 실험치가 잘 일치함을 보임으로서 실제 여과지(濾過池) 설계시 적용가능함을 알 수 있었다.

• 셀메드
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• 제10권3호
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• pp.19.1-19.6
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• 2020

The kidneys are exposed to toxicants and waste product and can be affected easily by these toxicants and by products of the metabolism. The consumption of adequate water is necessary to remove waste and to keep kidney healthy. Deficiency of liquid in the blood leads to various adverse effects on the kidney. The most common adverse deficiency of liquid in blood is deposition of solid matter in the kidney and subsequently formation of kidney stone. Nephrolithiasis (kidney stone) can be treated by drugs if it is small in size but if it blocks the route due to its big size then surgery is the only way to remove it. The recurrence rate of the problem is very high and it may reappear within 10 years. In Unani literature Hasāh wa Raml al-Kulya (nephrolithiasis) is described in detail. As per Unani literature stagnation of Ghalīz mādda (filthy and viscous matter) in the kidney is the main cause of the formation of kidney stone. Various single and compound formulations drugs are described for the management of kidney stone which are very effective as well as safe. Management is divided into two parts i.e. symptomatic treatment to relieve pain and to methods adopted to remove stone from the kidney. Musakkin-i-Waja'(analgesic) drugs are used for pain while Mufattit-i-Hasāh (lithotriptic) and Mudirr-i-Bawl (Diuretic) drugs are used to remove stone. Majoon Aqrab, Qurs Kaknaj and Dawa-e-Gurda etc. are compound drugs mentioned in literature for removal of kidney stone. Single drugs like Alu Balu, Tukhm Khayar, and Kharkhask etc. are also used for same purpose.

• 한국콘텐츠학회논문지
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• 제11권10호
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• pp.108-114
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• 2011

본 연구는 최근 침체위기를 맞고 있는 해외 한국어방송사들의 방송서비스 개선방안을 모색하기 위해 해외 교민들을 대상으로 방송콘텐츠 서비스의 주요 속성이 방송을 송출하는 해외 한국어방송사의 만족도에 영향을 미치는 과정을 탐색적으로 분석하였다. 본 연구에서는 해외 한국어방송사가 주로 제공하는 서비스를 방송콘텐츠의 완성도, 방송콘텐츠 제공의 효율성, 방송콘텐츠의 공익성이라는 세 가지의 틀로 구분하였고, 이러한 세가지 속성이 방송사에 대한 만족도에 영향을 주는 주요 요인으로 설정하였다. 또한 방송사의 내적요인과 외적요인이 방송사의 만족도에 직접적으로 영향을 주는 요인으로 설정하였다. 이러한 연구모형을 시청률이 낮은 집단과 높은 집단을 나누어 비교분석함으로써 해외한국어방송사에 대한 만족도 촉진을 향상시키기 위한 현실적인 대안을 제시하였다.

• 한국대기환경학회지
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• 제4권1호
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• pp.79-83
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• 1988

To improve working environment for the toll workers who were working at Kyungbu expressway in outskirts of Seoul and Suwon, the status of air pollution surrounding toll booth were measured from March 28 through June 14, 1986. The results were as follows: 1. The amount of TSP (total suspended particle) surrounding toll booth was directly proportional to the traffic load. The ratio of traffic load at Seoul and Suwon toll was 3.2:1 and of TSP was 2.6:1. 2. The proportion of particle larger than 5$\mum$ was 24.8 $\sim$ 34.9% of TSP at Seoul toll and 19.2 $\sim$ 32.7% at Suwon. The proportion of particle less than 2$\mum$ was 38.7 $\sim$ 51.8% of TSP at Seoul toll and 34.8 $\sim$ 54.8% at Suwon. 3. The concentration of respirable particle les than 7$\mum$ measured by personal air sampler was higher in Seoul toll booth than that of Suwon and it seems to be influenced by the exhausion of diesel engine. Especially the concentration of respirable particle of reformed toll booth with air curtain was 20% lower than unreformed one. 4. Concentration of Pb among suspended particles around Seoul toll was 5 times higher than Pb of Suwon toll. So it is considered that there were other possible pollution source of Pb beyond heavy traffic in Seoul toll area. The amount of Pb inside toll booth was extremely small but the concentration of benzo(a)pyrene showed a trend of increase according to traffic stagnation. 5. The concentration of $SO_2$ arround toll showed no difference between weekday and weekend and also showed no relation with traffic load. But the concentration of $NO_2$ was affected by traffic load.

• 대한한의학원전학회지
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• 제33권3호
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• pp.135-156
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• 2020

Objectives : This paper aims to suggest an integrated explanation for the contrary reinforcing/reducing effects of Shaoyao. Methods : From a list of books on the history of herbology and Chinese Medicine as mentioned in the herbology textbook, main texts were selected for further examination, along with some books of the Four Masters of the Jin Yuan period and some general medical texts. These texts were thoroughly examined with keywords such as Shaoyao, Baishaoyao, Chishaoyao, Baishao, Chishao, out of which contents on reinforcing and reducing were selected and analyzed. Next, explanations of the mechanisms of the contrary effects that were found through categorization of the reinforcing and reducing effects were examined. Among the contrary effects, similarities were uncovered and further studied for deduction of an encompassing higher level mechanism. Results & Conclusions : Overall consideration of the contrary effects of Shaoyao revealed that its working mechanism is to collect qi in the yin-blood part through convergence to control qi among blood, to help smooth flow of blood, eliminate blood stagnation and reinforce blood production which in turn cools down heat.