• 대한한의학원전학회지
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• 제33권1호
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• pp.149-158
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• 2020

Objectives : This study aims to examine the exterior relief method through pungent-cool properties in comparison to pungent-warm properties historically, to understand the meaning of 'exterior relief through pungent-cool' more thoroughly. Methods : Contents mentioning the treatment method directly were examined historically, then analyzed. Results & Conclusions : The method to relieve the exterior through pungent-cool properties has developed by overcoming the limitations of the method to relieve the exterior through pungent-warm properties since it was first established in 『Shanghanzabinglun』(『傷寒雜病論』). The term 'relief of the exterior through pungent-coolness'(辛凉解表) was first mentioned in the Ming period, referring to weak level of perspiration. Yetianshi(葉天士) explained it as communicating Weiqi(衛氣) using pungent-cool medicinals for heat to discharge through the exterior, resulting in mild sweating. In 『Wenbingtiaobian』(『溫病條辨』) the term 'to relieve the flesh'(解肌) refers to both mild sweating through pungent-warm medicinals and the opening of the exterior through pungent-cool medicinals for pathogenic qi to exit, resulting in sweating. If the exterior relief of the pungent-warm medicinals happens through the warm Yang qi(陽氣) stimulated the inner Yin fluids(陰液) to discharge as sweat, that through pungent-cool medicinals relieves stagnation in the exterior, opening up a way for the pathogenic heat to exit. From the perspective of the main therapeutic mechanism for pungent-cool medicinals to be its coolness relieving heat, the term 'exterior relief through pungent-coolness' becomes erroneous. For the 'exterior relief through pungent-coolness' category to be valid, the meaning of 'exterior relief' needs to be expanded to include not only stimulated sweating but the treatment process that could result in sweating.

• 한국수산과학회지
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• 제18권2호
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• pp.157-165
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• 1985

어장환경관리의 기본자료를 얻기 위하여 1984년 6월중에 가막만에서 실시한 해양관측자료를 가지고 상기만의 밀물과 썰물시 해황분포를 알아보고 그 특성이 지형적 요인에 의해 크게 좌우됨을 살폈다. 가막만은 두개의 만구와 돌출한 도서 및 지세 등 그 지형적 여건에 의해 4개의 특징적 수괴가 나타난다. 내만수는 내륙의 영향이 강한 정체성을, 여수항수는 섬진강 영향이 큰 저염의 외해성을, 만외수는 해저난류 또는 와류발생으로 수직균질한 외해성을, 중간수는 만외수와 내만수의 중간성격이다. 밀물때 양만구로 유입한 해수는 대략 소경도와 항대를 연결하는 선에서 만난다. 군내리근에서는 지형성 와류 혹은 해저난류가 발생하는 것으로 추정되는데, 밀물때는 해수의 침강이, 썰물때는 저층수의 특성치가 보여지며 그 크기는 약 3 km 까지 뻗친다.

• 한국수산과학회지
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• 제46권6호
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• pp.923-929
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• 2013

Black seabream juveniles Acanthopagrus schlegelii held at $20^{\circ}C$ were exposed to formalin at concentrations of 50 to 400 ppm, and tolerance values were determined by calculating median lethal concentration values (LC50) through probit analysis. The 12-, 24, 48, 72- and 96-h LC50 values for formalin were 297, 233, 171, 162 and 157 ppm, respectively. The histological effects of formalin on gill and liver tissues in this fish were determined. No histological effects were observed in the control group. The intensity of cell damage increased with the concentration of, and duration of exposure to, formalin. Hyperplasia, separation and epithelial necrosis, epithelial lifting, lamellar synechiae and collapsed lamellae were observed in gill tissues exposed to formalin. Hepatic lesions in liver tissues of fishes exposed to formalin were characterized by cloudy swelling of hepatocytes, necrosis, cytoplasmic vacuolization, deposition of pigments, spongiosis hepatis, nuclear hypertrophy, dilation of sinusoids and bile stagnation. The LC50 values and histological results obtained in this study will aid in designing treatment regimens to minimize toxic side effects and increase efficacy.

• 대한본초학회지
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• 제31권3호
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• pp.13-22
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• 2016

Objectives： Arachidonic acid is control the thromboxane A2 (TXA2) and prostacycline (PGI2) synthesis, TXA2 increase lead to thrombus produced by induces platelet aggregation and vasoconstriction. Angelicae gigantis radix (RAR) is mainly used blood deficiency and stagnation. In previous studies, RAR has been reported that a vasodilating and blood clotting delay effects. In this study, investigate that anti-oxidant and anti-thrombotic effects of RAR by heat-process.Methods： The heated angelicae gigantis radix sample were made by 140, 180, and 220 ℃ and 4, 6, 9 and 12 min using water or 30% ethanol. The anti-oxidant effects were measured by total polyphenol, total flavonoid, DPPH and ABTS radical scavening activation. Anti-thrombotic effect conducted in samples that are determined to be effective through the anti-oxidant experiment such as angelicae gigantis radix roasted 180℃, and 220℃ and angelicae gigantis radix roasted with 30% ethanol 180℃, and 220℃.Results： Anti-oxidant parameters were efficacious in high temperature roasted AR. Also AR and EAR increased a inhibitory activity of FXa compared with RAR. The blood coagulation time of administration groups were significantly increased compare with control group. The TXB2 was significantly decreased in AR and EAR.Conclusions : We confirmed that whether AR and EAR administration has anti-oxidant and anti-thrombotic effect or not. As the results, AR and EAR were improved anti-oxidant effects and blood biochemistry compare with control group. This study provides scientific evidence that AR and EAR are have an anti-oxidant effect and anti-thrombotic effect, it expected that there is no difference between the two.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2008년도 제30회 춘계학술대회논문집
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• pp.321-327
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• 2008

초음속 디퓨져를 사용하는 고도모사 장치에서 기존에 연구되었던 일정단면적 형태를 개선해 2차 목 형태 디퓨져의 효과를 고찰하였다. 기 수행 된 일정단면적 디퓨져 정상상태 해석 결과 및 공압시험 데이터를 바탕으로 본 연구의 해석방법을 검증하고, 2차목에 의한 효과를 정량화시키기 위해 노즐전압력과 2차목 면적에 따른 시동성능과 진공챔버압력 변화에 관하여 해석하였다. 일정단면적 디퓨져 내부 벽면 및 중심축을 따른 압력데이터 비교에서 일치하는 거동을 확인했으며, 2차목의 사용에 의해 시동을 위한 노즐 전압력이 현저히 낮아짐을 알 수 있었다. 저팽창비 노즐 사용으로 인하여 2차목에 의한 진공챔버 내 압력 변화는 거의 없음을 관찰하였다.

• 혜화의학회지
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• 제20권1호
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• pp.11-23
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• 2011

Systemic Lupus Erythematosus(SLE) is an autoimmune disease invading the skin, joint, kidney, intestinal membrane, neurosystem and other organs. SLE is an autoimmune disease characterized by immune dysregulation resulting in the production of antinuclear antibodies(ANA), generation of circulating immune complexes, and activation of the complement system. In Korean medicine, lupus can be classified as acute arthritis, reddish butterfly erythema, asthenic disease, edema and so on. The cause and procedure of the diseases are flourishing noxious heat, excessive fire due to deficiency of yin, blood stasis due to stagnation of qi, internal movement of the liver-wind, congenital deficiency, exhausted vital-qi, which are treated by clearing away heat and cooling the blood, nourshing yin and extinguishing fire, treating flatulence and activating blood circulation, nourishing the blood to expel wind, invigorating the liver and kidney, invigorating qi and replenishing the blood. To experimentally examine the influence of Insam-Buja-Tang (Ginseng & Aconiti Extract, IBT) on the outbreak and development of lupus, lupus induce MRL/MpJ-Faslpr lupus-prone mice model was used. As IBT was orally administrated to a lupus model mouse, various tests such as the weight, urine protein, renal function, Lymph cell test of the spleen, Cytokine expression, histopathological analysis of kideny were performed to see the influence on the kidney and whether it work effectively on the immune function. The main purpose of this study is to evaluate the effect of IBT on MRL/MpJ-Faslpr lupus-prone mice model. The effect of IBT on MRL/MpJ-Faslpr lupus-prone mice that can have autoimmune disease similar to SLE in human was evaluated after IBT per oral in the present study.

• 한국환경과학회지
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• 제22권9호
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• pp.1115-1129
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• 2013

The study area is located on the western coast, and the inner development construction has been ongoing since 2011. The purposes of current study are to effectively simulate and quantitatively predict a temporal and spatial distributions of water temperature and salinity due to the stages of inner development construction in saemangeum reclaimed area. The transient-state numerical modeling using EFDC model is done, and the numerical simulation results are validated reasonably by repetitive numerical model calibration procedures with respect to field measurements of water temperature and salinity. The spatial distributions of water temperature and salinity show similar trends before and after construction of the dikes. In spring season, the salinity has maximum value of 21 psu, while, in summer season, the salinity shows 7 psu in a whole modeling domain. Thus, it is clearly observed that salt water is replaced by freshwater. However, the salinity and temperature reach their initial conditions at the end of the year. The salinity after construction of the dikes is lower than that before construction of them at Mankyeong area. On the other hands, after construction of the dikes, the salinity after dredging operations is higher than that before dredging. Because drastical increasing of water volume in Saemangeum Lake leads to increasing of stagnation time at bottom layer, and salt water is easily intruded to the two estuaries. Therefore, it may be concluded that hydrodynamic characteristics on Saemangeum are dominated by either Mankyeong and Dongjin discharge or sluice gates in/out-flow amounts, and thus they must be properly considered when rigorous and reasonable predictions of water temperature and salinity according to the stages of inner development construction.

• 대한한방내과학회지
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• 제16권1호
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• pp.40-61
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• 1995

This study was performed to investigate concept, systoms, causes of disease, pathogenic mechanisms, therapies and precriptions about senile constipation through the successive medical literature, recent chinese medical literature and chinese medical joumals. Senile constipation seems to be applicable to dryness syndrom and constipation of insufficiency type, have something to do with kidney(the most), lung, spleen and large intestine. The most principal cause of disease is yin-fluid, the rest deficiency of qi, insufficiency of yang, stagnation of qi and retention of fever etc. There are enriching the blood and moistening dryness in principal therapy, the rest are invigorating qi and loosing the bowel, warming and invigorating the spleen and kidney, regulating the flow of qi and promoting the stagnancy of qi and expelling the pathogenic heat etc. In prescriptions there are Yunjangtang, Jengaektang, Hwanggitang, Jechunjeon, Yukmatang and Majainhwan as the causes of disease, meanwhile are Yungjang-tang, Jechunjeon and Majainhwan in the vulgaris prescriptions. And in medical herbs there are nourishing yin medicines as Rhizoma rehmanniac, Radix ophiopogonis and Radix scrophulariae etc., invigorating qi medicines as Radix astragali, Radix codonopsitis and Radix polygoni multiflori etc, invigorating yang medicines as Caulis cistanchis and Semen psoraleae etc., promoting qi circulating medicines as Radix saussurea, Lignum aquilariae and Radix linderae etc., and reducing fever and therapeutic method to keep the adverse qi flowing downward medicines as Semen cannabis, Rhizoma rhei, Fructus immaturus ponciri, and Cortex magnoliae etc.. Meantime Rhizoma rehmanniae, Radix ophiopogonis, Caulis cistanchis, Radix angelicae gigantis, Semen cannabis, Semen biotae, Semen pruni japonicae and Semen persicae in principal herb-medicines. In clinical reports the process of disease was between 10 to 20 years, the evacuation cycle between 4 to 7 days, generally possessed chronic diseases as hypertension, diabetes, arteriosclerosis and cerebro- vascular disorders etc. and the efficiency rate was more than 90%. The senile constipation is occured in succession or promoted by chronic diseases as obesity, hypertension, diabetes, arteriosclerosis. hrperlipemia, cerebro- vascular disorders etc., so diet-regulating, adequate exercise, proper evacuation-habit and psychologic rest etc. are important more than medicine-treatments.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2005년도 춘계학술대회 논문집
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• pp.353-358
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• 2005

이 논문의 목적은 연안여객선의 항로에 공적개념을 도입시켜 항로전체의 편익을 증대하고, 업체 간 잠재적 경쟁원리를 도입하여 업체효율성을 향상시키는 실행방향에 대한 연구를 목적으로 한다. 2005년 현재 우리나라의 연안여객선은 목포, 마산, 인천 등 10여개의 생활거점 항구도시를 중심으로 106개 항로에 취항하여 이들 도서 주민의 생활교통을 담당하고 있다. 이렇듯 중요한 연안여객선이 다른 교통수단과는 대조적으로 일부 관광항로를 제외하고는 대부분 정체 내지 낙후성을 면치 못한 관계로 주민들이 다양한 서비스욕구를 충족시키지 못하고 있다. 또한 항로가 사유 재산권화 되어 있어 인위적인 항로조정 및 탄력적 선박운행을 기대할 수 없다. 따라서 도시와 도서간에 생활권 형성과 도서지역의 관광산업 등 경제활동의 활성화 제고 및 국토의 균형적 발전을 위하여 연안여객선의 대중교통화를 제안한다.

• 대한지리학회지
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• 제50권1호
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• pp.105-122
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• 2015

군사지리학은 지리과학 기술과 지식을 전쟁에 활용하는 관점에서 1960년대에 출현한 응용지리학의 한 분야로 인식되어 왔다. 그러나 폭력 행위를 수반하는 전쟁에 대한 기여는 학문 연구의 도덕적 측면에서 부정적 인식을 초래하였고, 이는 학문 연구의 침체로 이어졌다. 본 연구는 응용지리학으로서 군사지리학의 역할을 제고하기 위한 방안을 제시하는 데 그 목적을 두었다. 이를 위해 군사지리학의 역할에 대한 본질적인 의미를 전쟁과 군사학과의 관계 속에서 고찰하였다. 이를 바탕으로 군사지리학 연구가 기존의 전쟁 기여 위주의 시각에서 벗어나 인류의 발전에 기여하는 역할로 새로운 정립이 필요하다는 관점의 연구 방향을 제시하였다. 군사지리학의 연구 기능은 연구 방향의 관점에 따라 전쟁에 기여하기도 하고 인류의 삶 증진에 기여할 수도 있는 이중적 속성을 대부분 가지고 있다. 군사지리학 연구가 지금까지는 전쟁기여에 필요한 활용성에 초점을 맞추어 왔으나 향후에는 인류의 삶 증진에 기여하는 역할을 확대함으로써 도덕성 측면의 미흡성을 보완해 나갈 수 있을 것이다. 본 연구를 통해 군사지리학이 전쟁과 평화 모두에 기여할 수 있는 완전한 학문으로의 역할 수행에 대한 가능성을 확인할 수 있었다.