• Journal of Korean Medical classics
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• v.33 no.1
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• pp.149-158
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• 2020

Objectives : This study aims to examine the exterior relief method through pungent-cool properties in comparison to pungent-warm properties historically, to understand the meaning of 'exterior relief through pungent-cool' more thoroughly. Methods : Contents mentioning the treatment method directly were examined historically, then analyzed. Results & Conclusions : The method to relieve the exterior through pungent-cool properties has developed by overcoming the limitations of the method to relieve the exterior through pungent-warm properties since it was first established in 『Shanghanzabinglun』(『傷寒雜病論』). The term 'relief of the exterior through pungent-coolness'(辛凉解表) was first mentioned in the Ming period, referring to weak level of perspiration. Yetianshi(葉天士) explained it as communicating Weiqi(衛氣) using pungent-cool medicinals for heat to discharge through the exterior, resulting in mild sweating. In 『Wenbingtiaobian』(『溫病條辨』) the term 'to relieve the flesh'(解肌) refers to both mild sweating through pungent-warm medicinals and the opening of the exterior through pungent-cool medicinals for pathogenic qi to exit, resulting in sweating. If the exterior relief of the pungent-warm medicinals happens through the warm Yang qi(陽氣) stimulated the inner Yin fluids(陰液) to discharge as sweat, that through pungent-cool medicinals relieves stagnation in the exterior, opening up a way for the pathogenic heat to exit. From the perspective of the main therapeutic mechanism for pungent-cool medicinals to be its coolness relieving heat, the term 'exterior relief through pungent-coolness' becomes erroneous. For the 'exterior relief through pungent-coolness' category to be valid, the meaning of 'exterior relief' needs to be expanded to include not only stimulated sweating but the treatment process that could result in sweating.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.18 no.2
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• pp.157-165
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• 1985

Character of oceanic conditions in the bay is investigated by taking hydrographic data on june in Kamak Bay which has two channels and four submarine topographic parts of its own. This bay has four remarkable water mass influenced greatly by the above topographical factor: inner bay water, Yosu harbor water, the middle water and outer bay water. General characteristics of these four water mass were as fellows: inner bay water has a stagnation character with the influence of inland, Yosu harbor water has a out-sea character with the low salinity caused by run-off of Somjin river, outer bay water has a out-sea character with same values vertically coused by eddy current or bottom turbulunce and the middle water has a middle character among the inner bay water and outer bay water. Outer waters flowed in the bay through both channels during the flood are come upon at a near by Daekyong-do and Hangdae-ri of Dolsan-do. Eddy current or bottom turbulunce in the vincinity of Kunnae-ri which is located at south of the bay are showed sinking of water during the flood flow, while that during the ebb flow shelved up-welling phenomena.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.46 no.6
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• pp.923-929
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• 2013

Black seabream juveniles Acanthopagrus schlegelii held at $20^{\circ}C$ were exposed to formalin at concentrations of 50 to 400 ppm, and tolerance values were determined by calculating median lethal concentration values (LC50) through probit analysis. The 12-, 24, 48, 72- and 96-h LC50 values for formalin were 297, 233, 171, 162 and 157 ppm, respectively. The histological effects of formalin on gill and liver tissues in this fish were determined. No histological effects were observed in the control group. The intensity of cell damage increased with the concentration of, and duration of exposure to, formalin. Hyperplasia, separation and epithelial necrosis, epithelial lifting, lamellar synechiae and collapsed lamellae were observed in gill tissues exposed to formalin. Hepatic lesions in liver tissues of fishes exposed to formalin were characterized by cloudy swelling of hepatocytes, necrosis, cytoplasmic vacuolization, deposition of pigments, spongiosis hepatis, nuclear hypertrophy, dilation of sinusoids and bile stagnation. The LC50 values and histological results obtained in this study will aid in designing treatment regimens to minimize toxic side effects and increase efficacy.

• The Korea Journal of Herbology
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• v.31 no.3
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• pp.13-22
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• 2016

Objectives： Arachidonic acid is control the thromboxane A2 (TXA2) and prostacycline (PGI2) synthesis, TXA2 increase lead to thrombus produced by induces platelet aggregation and vasoconstriction. Angelicae gigantis radix (RAR) is mainly used blood deficiency and stagnation. In previous studies, RAR has been reported that a vasodilating and blood clotting delay effects. In this study, investigate that anti-oxidant and anti-thrombotic effects of RAR by heat-process.Methods： The heated angelicae gigantis radix sample were made by 140, 180, and 220 ℃ and 4, 6, 9 and 12 min using water or 30% ethanol. The anti-oxidant effects were measured by total polyphenol, total flavonoid, DPPH and ABTS radical scavening activation. Anti-thrombotic effect conducted in samples that are determined to be effective through the anti-oxidant experiment such as angelicae gigantis radix roasted 180℃, and 220℃ and angelicae gigantis radix roasted with 30% ethanol 180℃, and 220℃.Results： Anti-oxidant parameters were efficacious in high temperature roasted AR. Also AR and EAR increased a inhibitory activity of FXa compared with RAR. The blood coagulation time of administration groups were significantly increased compare with control group. The TXB2 was significantly decreased in AR and EAR.Conclusions : We confirmed that whether AR and EAR administration has anti-oxidant and anti-thrombotic effect or not. As the results, AR and EAR were improved anti-oxidant effects and blood biochemistry compare with control group. This study provides scientific evidence that AR and EAR are have an anti-oxidant effect and anti-thrombotic effect, it expected that there is no difference between the two.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.05a
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• pp.321-327
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• 2008

Performance characteristics of the axi-symmetric supersonic exhaust diffuser (SED) with a second throat are numerically investigated. Computational strategy repeats those for a straight exhaust diffuser with zero-secondary flows. Renolds-Average Navier-Stokes equations with a standard ${\kappa}-{\varepsilon}$ turbulence model incorporated with standard wall function are solved to simulate the diffusing evolutions of the nozzle plume. The methodology is validated with accuracy. To predict the improvement of starting performance by second throat diffuser, diffuser characteristic curve due to the SED equipped with the second throat is speculated with respect to that of a straight area type as a function of nozzle stagnation pressure. Principal physics caused by the of the second throst is also addressed in terms of a second throat area ratio.

• Journal of Haehwa Medicine
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• v.20 no.1
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• pp.11-23
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• 2011

Systemic Lupus Erythematosus(SLE) is an autoimmune disease invading the skin, joint, kidney, intestinal membrane, neurosystem and other organs. SLE is an autoimmune disease characterized by immune dysregulation resulting in the production of antinuclear antibodies(ANA), generation of circulating immune complexes, and activation of the complement system. In Korean medicine, lupus can be classified as acute arthritis, reddish butterfly erythema, asthenic disease, edema and so on. The cause and procedure of the diseases are flourishing noxious heat, excessive fire due to deficiency of yin, blood stasis due to stagnation of qi, internal movement of the liver-wind, congenital deficiency, exhausted vital-qi, which are treated by clearing away heat and cooling the blood, nourshing yin and extinguishing fire, treating flatulence and activating blood circulation, nourishing the blood to expel wind, invigorating the liver and kidney, invigorating qi and replenishing the blood. To experimentally examine the influence of Insam-Buja-Tang (Ginseng & Aconiti Extract, IBT) on the outbreak and development of lupus, lupus induce MRL/MpJ-Faslpr lupus-prone mice model was used. As IBT was orally administrated to a lupus model mouse, various tests such as the weight, urine protein, renal function, Lymph cell test of the spleen, Cytokine expression, histopathological analysis of kideny were performed to see the influence on the kidney and whether it work effectively on the immune function. The main purpose of this study is to evaluate the effect of IBT on MRL/MpJ-Faslpr lupus-prone mice model. The effect of IBT on MRL/MpJ-Faslpr lupus-prone mice that can have autoimmune disease similar to SLE in human was evaluated after IBT per oral in the present study.

• Journal of Environmental Science International
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• v.22 no.9
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• pp.1115-1129
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• 2013

The study area is located on the western coast, and the inner development construction has been ongoing since 2011. The purposes of current study are to effectively simulate and quantitatively predict a temporal and spatial distributions of water temperature and salinity due to the stages of inner development construction in saemangeum reclaimed area. The transient-state numerical modeling using EFDC model is done, and the numerical simulation results are validated reasonably by repetitive numerical model calibration procedures with respect to field measurements of water temperature and salinity. The spatial distributions of water temperature and salinity show similar trends before and after construction of the dikes. In spring season, the salinity has maximum value of 21 psu, while, in summer season, the salinity shows 7 psu in a whole modeling domain. Thus, it is clearly observed that salt water is replaced by freshwater. However, the salinity and temperature reach their initial conditions at the end of the year. The salinity after construction of the dikes is lower than that before construction of them at Mankyeong area. On the other hands, after construction of the dikes, the salinity after dredging operations is higher than that before dredging. Because drastical increasing of water volume in Saemangeum Lake leads to increasing of stagnation time at bottom layer, and salt water is easily intruded to the two estuaries. Therefore, it may be concluded that hydrodynamic characteristics on Saemangeum are dominated by either Mankyeong and Dongjin discharge or sluice gates in/out-flow amounts, and thus they must be properly considered when rigorous and reasonable predictions of water temperature and salinity according to the stages of inner development construction.

• The Journal of Internal Korean Medicine
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• v.16 no.1
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• pp.40-61
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• 1995

This study was performed to investigate concept, systoms, causes of disease, pathogenic mechanisms, therapies and precriptions about senile constipation through the successive medical literature, recent chinese medical literature and chinese medical joumals. Senile constipation seems to be applicable to dryness syndrom and constipation of insufficiency type, have something to do with kidney(the most), lung, spleen and large intestine. The most principal cause of disease is yin-fluid, the rest deficiency of qi, insufficiency of yang, stagnation of qi and retention of fever etc. There are enriching the blood and moistening dryness in principal therapy, the rest are invigorating qi and loosing the bowel, warming and invigorating the spleen and kidney, regulating the flow of qi and promoting the stagnancy of qi and expelling the pathogenic heat etc. In prescriptions there are Yunjangtang, Jengaektang, Hwanggitang, Jechunjeon, Yukmatang and Majainhwan as the causes of disease, meanwhile are Yungjang-tang, Jechunjeon and Majainhwan in the vulgaris prescriptions. And in medical herbs there are nourishing yin medicines as Rhizoma rehmanniac, Radix ophiopogonis and Radix scrophulariae etc., invigorating qi medicines as Radix astragali, Radix codonopsitis and Radix polygoni multiflori etc, invigorating yang medicines as Caulis cistanchis and Semen psoraleae etc., promoting qi circulating medicines as Radix saussurea, Lignum aquilariae and Radix linderae etc., and reducing fever and therapeutic method to keep the adverse qi flowing downward medicines as Semen cannabis, Rhizoma rhei, Fructus immaturus ponciri, and Cortex magnoliae etc.. Meantime Rhizoma rehmanniae, Radix ophiopogonis, Caulis cistanchis, Radix angelicae gigantis, Semen cannabis, Semen biotae, Semen pruni japonicae and Semen persicae in principal herb-medicines. In clinical reports the process of disease was between 10 to 20 years, the evacuation cycle between 4 to 7 days, generally possessed chronic diseases as hypertension, diabetes, arteriosclerosis and cerebro- vascular disorders etc. and the efficiency rate was more than 90%. The senile constipation is occured in succession or promoted by chronic diseases as obesity, hypertension, diabetes, arteriosclerosis. hrperlipemia, cerebro- vascular disorders etc., so diet-regulating, adequate exercise, proper evacuation-habit and psychologic rest etc. are important more than medicine-treatments.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.29 no.1
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• pp.353-358
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• 2005

The purpose of this study is to implement concept of public to passenger ship route to promote benefits and adopt competition principle among ship companies to elevate business efficiency. As of year 2005, passenger ships operate in 106 routes departing from 10 harbors including Mokpo, Masan, and Inchonto provide transportation system to island residents. Contrast to other public transportation systems excluding some tourism routes, this essential passenger ship are unable to fulfill various customer services to the passengers due to stagnation or declination. In addition, route adjustment and flexible passenger ship operation are not expected due to private property right of the route. Therefore, establishment of public transportation system for remote island route is initiated for the connection between cities and islands, boost travel industry of island economy, and balanced growth oh the nation.

• Journal of the Korean Geographical Society
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• v.50 no.1
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• pp.105-122
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• 2015

Military geography has been recognized a part of applied geography appeared in 1960s by the viewpoint applying geographical science technology and knowledge for war. But the contribution for war accompanying violence caused negative recognition in moral viewpoint and led stagnation of military geography's study. Therefore this paper has researched a method improving the role of military geography as a part of applied geography and considered the essential meaning of the military geography's role in the relationship between war and military sciences. Based on this consideration, this paper proposed a research direction necessary for the role contributing human development beyond the viewpoint focusing contribution for war. The result of this study confirmed the characters of the military geography's elements have two attributes contributing for war victory or improving human life quality. Military geography has laid emphasis for usability to war contribution until now and caused unsatisfactoriness of morality. But military geography can complement this unsatisfactoriness by the extension of the role contributing human life quality. This study could examine the possibility doing the role contributing for both war and peace as a intact science.