• Bulletin of the Korean Chemical Society
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• v.14 no.2
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• pp.262-265
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• 1993

Conformational free energy calculations using an empirical potential function and a hydration shell model (program CONBIO) were carried out on antifungal agent fluconazole in the unhydrated and hydrated states. The initial geometry of fluconazole was obtained from two minimized fragments of it using a molecular mechanics MMPMI and followed by minimizing with a semiempirical AM1 method. In both states, the feasible conformations were obtained from the calculations of conformational energy, conformational entropy, and hydration free energy by varying all the torsion angles of the molecule. The intramolecular hydrogen bonds of isopropyl hydroxyl hydrogen and triazole nitrogens and the structural flexibility are of significant importance in stabilizing the conformations of fluconazole in both states. Hydration is proved to be one of the essential factors in stabilizing the overall conformation in aqueous solution. Two F atoms of phenyl ring are not identified as an essential key in determining the stable conformations and may be responsible for the interaction with the receptor of fluconazole.

• Economic and Environmental Geology
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• v.56 no.5
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• pp.619-628
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• 2023

In this study, we investigated the feasibility of calcium sulfate fertilizer as a stabilizing agent for As and Hg contaminated farmland soil and its stabilization characteristics in 3 different physical forms (particulate, powder, and solution) through a pot experiment including 34 days of lettuce growth. As and Hg contents of the lettuce grown in the stabilized soils were decreased by at least 70%. However the lettuce yield of the soil stabilized with the solution agent was decreased by 46% due to the overabundance of the nutrients from the solution agent. Thus, if a solution-type agent is planned for agricultural farmland soil stabilization, additional tests for optimal dosage are needed to preserve vegetation growth. In Hg fractionation, a lower concentration of elemental fractions and a higher concentration of residual/sulfide fractions were identified in the soils stabilized with the solution, powder, and pariculate agents in descending order while there were no significant changes in As fractionation. Overall results suggest that calcium sulfate fertilizer can be used as a stabilizing agent, and a solution-type agent could be used when the operation of heavy machinery for the soil stabilization process is impossible.

• Journal of the Korean Geotechnical Society
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• v.22 no.11
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• pp.143-149
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• 2006

An experimental study was carried out to investigate the stabilizing capability of oyster shell binder, which was developed using waste oyster shell inducing environmental pollutions by piling up out at the open or the temporary reclamation. The purpose of this paper is to compare stabilinzing capability of oyster shell binder and cement binder with treated soils. For this, a series of compressive laboratory tests were peformed to evaluate strength characteristics of treated soils by both oyster shell binder and cement binder with varing water content of dredged soils, different mixing rates of binder and curing days. Based on test results, eco-friendly binder manufactured by oyster shells showed more stabilizing capacity than cement binder and is estimated as good resource materials for soft soil improvements.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2010.03a
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• pp.137-138
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• 2010

• Journal of the Korea Institute of Building Construction
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• v.7 no.2 s.24
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• pp.77-83
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• 2007

This study investigated the fundamental properties of the lightweight foamed concrete depending on various admixtures, and the results were summarized as following. When 20% of cement kiln dust(CKD) and 0.002% of stabilizing agent were mixed to lightweight foamed concrete, it was necessary to use a superplasticizer because flowability was decreased. However, it could reduce sinking depth which were the extensive trouble of lightweight foamed concrete. Bulk density was divided into '0.4' and '0.5' grades on KS according to unit volume weight. The compressive strength was less than that of plain concrete when admixtures were applied, but the results exceeded the minimum strength of the each grades on KS. Totally, it is found that the combination of 20% of CKD and 0.002% of stabilizing agent makes it possible to reduce a sinking depth, recycle resources, and save cost when were mixed.

• Journal of Pharmaceutical Investigation
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• v.27 no.1
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• pp.23-27
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• 1997

To investigate the effect of L-arginine as stabilizing agent for omeprazole, the degradation rate constant of omeprazole in aqueous solution was determined at 30, 40 and $50^{\circ}C$ with various ratios of L-arginine to omeprazole. The pH of omeprazole solutions was also determined. As the amount of L-arginine increased, the pH of omeprazole solution also increased, and the solution appeared to be more stable. The omeprazole in aqueous solution could be stabilized by more than 15:1 molar ratio of L-arginine to omeprazole. The stability of omeprazole in commercial products using L-arginine or sodium phosphate dibasic as stabilizing agent was investigated. Among the commercial products, the omeprazole product prepared with L-arginine (molar ratio of L-arginine to omeprazole, 20:1) was most stable.

• Bulletin of the Korean Chemical Society
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• v.32 no.1
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• pp.117-121
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• 2011

Size-controlled Ag nanoparticles (NPs) were prepared from the decomposition of Ag(I) carboxylates using ethanolamine derivatives as a reducing agent without an additional stabilizing agent. The size of the Ag NPs with a narrow size distribution (sub-10 nm to ca. 40 nm) was controlled precisely by varying the processing parameters, such as the type of reducing agent and the chain length of the carboxylate in the Ag(I) carboxylate. The optical properties, surface composition and crystallinity of the Ag NPs were characterized by ultraviolet-visible spectroscopy, gas chromatography-mass spectrometry, thermal gravimetric analysis, transmission electron microscopy and X-ray diffraction.

• Geomechanics and Engineering
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• v.37 no.5
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• pp.499-510
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• 2024

In northern China, abundant summer rainfall and a higher water table can weaken the soil due to salt heave, collapsibility, and increased moisture absorption, thus the chlorine saline soil (silty clay) needs to be stabilized prior to use in road embankments. To optimize chlorine saline soil stabilizing programs, unconfined compressive strength tests were conducted on soil treated with five different stabilizers before and after soaking, followed by field compaction test and unconfined compressive strength test on a trial road embankment. In situ testing were performed with the stabilized soils in an expressway embankment, and the results demonstrated that the stabilized soil with lime and SH agent (an organic stabilizer composed of modified polyvinyl alcohol and water) is suitable for road embankments. The appropriate addition ratio of stabilized soil is 10% lime and 0.9% SH agent. SH agent wrapped soil particles, filled soil pores, and generated a silk-like web to improve the moisture stability, strength, and stress-strain performance of stabilized soil.

• Journal of the Korean GEO-environmental Society
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• v.2 no.2
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• pp.59-64
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• 2001

Recently, the application of shallow mixing method using hardening agent has increased because of the advantage of securing trafficability, reducing the working period, solving environmental problems caused by dumped and replaced soil, etc. In this paper, three types of representative hardening agents in Korea are used to achieve the optimum of ground improvement. 1he unconfined compression tests are carried out with specimens under various mixing ratios and curing periods of hardening agent to assess the stabilizing ability. The unconfined strengths on site were estimated with various mixing ratios based on the results of the laboratory tests. It was estimated that the improved strength on site was higher than that of the required strength $5.0kgf/cm^2$.

• Journal of Power System Engineering
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• v.4 no.2
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• pp.31-39
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• 2000

Relationships between the plating condition and the plating rate of the deposition film for the electroless plating of Co-Cu-P alloy were discussed in this report. The result obtained from this experiment were summarized as follow ; The optimum bath composition was consisted of 0.8 ppm thiourea as a stabilizing agent. Composition of the deposit was found to be uniform after two hours of electroless plating. Plating rates of nickel-catalytic surface and zincate-catalytic surface were found to be very closely equal, but the plating time of nickel-catalytic surface took longer than that of the zincated-catalytic surface.