• Journal of Pharmaceutical Investigation
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• v.33 no.4
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• pp.293-298
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• 2003

This study was attempted to develop the physicochemical ad morphological stability test methods for the cream and lotion formulations among the cosmetic foundations and to provide the guidance for the stability methods with respect to basic emulsions and creams. With these developed stability test methods, we can evaluate the expired date or life time of the available basic cosmetics, especially basic lotions ad creams. Also, the stability test methods established in this study can be used as a guideline to test physical and morphological stability of cosmetics in the future. Thus, we selected two types of basic cosmetics such as lotions and creams made by four different cosmetic companies ad applied them to the stability test methods depending on the temperature changes such as temperature cycling and freezing-thawing cycling test. After the temperature changes, the conductivity, turbidity, particle size, creaming ratio and pH changes of the creams and lotions were evaluated and morphological changes such as crystal formation, odor, color and feeling of the creams and lotions were also tested. As the results of the stability tests, all the tested creams and lotions except for one lotion were stable. Therefore, it may be concluded that these short-term accelerated stability tests as physical stability test depending on the temperature change study were suitable for the stability testing methods for the basic cosmetics and may be useful for the establishment of the guideline for the stability test of cosmetics.

• Journal of Korean Tunnelling and Underground Space Association
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• v.16 no.1
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• pp.91-104
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• 2014

An Excavation Damaged Zone (EDZ), in which rock properties are permanently changed due to blasting impact or stress redistribution, can influence the behavior and stability of structures. In this study, the mechanical stability of an underground opening was simulated by using FLAC, which is a two-dimensional modeling code, with a consideration of EDZ. A sensitivity analysis was also carried out with fractional factorial design. From the modeling, it was found that the behavior and the stability of an underground tunnel are strongly dependent on the existence of the EDZ. The sensitivity analysis showed that the key parameters affecting the factor of safety around the tunnel are in-situ stress ratio, depth, cohesion, reduction ratio, internal friction angle, and height and width of the tunnel. It is necessary to consider the EDZ, which can significantly affect mechanical stability in tunnel design.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.2
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• pp.119-131
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• 2012

The W/O emulsion is widely used for cosmetics because of its water-proofing benefit and long-lasting moisturizing effect. However, because of low stability of the W/O emulsion, it is very important to control the concentration of electrolyte and emulsifying agent, and ratio of water phase. Among these factors, we focused on the effects of different structures of emulsifying agents on the change of stability. Emulsifying agents were sorted into polyglyceryl ester, silicone and sugar series. We also examined the emulsifyingability of emulsifier by changing the ratio of normal and silicon oil in the oil phase. Through these experimental results, we figured out the property of w/o emulsion depending on the types of emulsifiers, and observed the stability of emulsion considering the change of particles and viscosity over time.

• KSBB Journal
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• v.32 no.2
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• pp.108-116
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• 2017

Omeprazole, a benzimidazole derivative, suppresses gastric acid secretion by inhibiting $H^+/K^+$ ATPase in gastric parietals cells, and by reducing $H^+$ concentration. To improve stability of esomeprazole magnesium dihydrate (ESMD), enteric-coated preperation was composed of core tablet, subcoating and enteric coating layer. We were evaluated in vitro dissolution characteristics between test and reference ESMD preparation and stability. We could prepare enteric-coated formulation of ESMD by controlling disintegrating agent and coating ratio which could rapidly dissolved in neutral or alkali medium. The formulation D5 with crospovidone of 1.25% and coating ratio of 16.25% had a similar dissolution behavior compare to reference preparation. Difference factor ($f_1$) and similarity factor ($f_2$) were 0~15 and 50~100 and there was no significant difference in bioequivalence between formulations. The content and dissolution rate of formulation D5 were $96.54{\pm}0.21$ and $78.56{\pm}0.87%$ without change of color in accelerated condition ($40^{\circ}C$, RH 75%, high density polyethylene (HDPE) container) for 6 months. This study concluded that our enteric coated preparation of ESMD could be an useful method to improve stability of unstable drug without direct contact with coating material.

• The Korean Journal of Food And Nutrition
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• v.29 no.6
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• pp.985-997
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• 2016

The objectives of this study, which filled gaps in previous studies, were: (1) to find the optimal mixing condition of nanoemulsions containing oleoresin capsicum (OC), Tween 80, propylene glycol (PG), and sucrose monostearate (SES) by microfluidization; (2) to investigate their properties and stability depending on such factors as pH, temperature, and heating time; (3) to measure the effect of adding ascorbic acid. In order to test these objectives, the following three experiments were conducted: Firstly, in order to find the optimal mixing ratio, nanoemulsions containing OC - the mean diameter of which is smaller than 100 nm - were prepared through the process of microfluidization; and their mean particle size, zeta potential, and capsaicinoids were measured. The test results indicated that the mixing ratio at OC : Tween 80 : PG + water(1:2) = 1 : 0.2 : 5 was optimal. Secondly, the properties and stability of nanoemulsions were investigated with varying parameters. The test results illustrated that single-layer nanoemulsions and double-layer nanoemulsions coated with alginate were stable, irrespective of all the parameters other than/except for pH 3. Thirdly, the properties of nanoemulsions were then analyzed according to the addition of ascorbic acid. The results demonstrated that the properties of single-layer nanoemulsions were not affected by addition of ascorbic acid. In case of alginate double-layer nanoemulsions, the particle size was reduced, and zeta potential increased with the addition of ascorbic acid. In conclusion, the demonstrated stability of various nanoemulsions under the different conditions in the present study suggests that these findings may constitute a basis in manufacturing various food-grade products which use nanoemulsions-and indicate that food nanoemulsions, if adopted in the food industry, have the potential to satisfy both the functionality and acceptability requirements necessary to produce commercially marketable food-grade products.

• Journal of International Academy of Physical Therapy Research
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• v.2 no.1
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• pp.229-236
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• 2011

The purpose of this study was to comparatively analyze the active stability of shoulder joints according to the frequency of overhead motions, such as serving and spiking, engaged in by female professional volleyball athletes who play different positions, and to provide the results as the basic data for developing exercise programs to prevent shoulder joint injuries. The subjects of this study were 50 Korean female professional volleyball players and positions were as follows: left and right attackers, centers, setters, and liberos. The external rotation and internal rotation muscle strength and muscle strength ratios of the dominant and non-dominant arms of all subjects were measured using Biodex. The results of this study are as follows: Frist, no significant differences were found in the internal and external rotation muscle strength of the dominant and non-dominant arms between positions. Second, for the shoulder joint muscle strength ratio of the dominant arm, by position, the setter showed significantly greater stability compared to the other positions. Third, for the shoulder joint muscle strength ratio of the non-dominant arm, by position, no significant difference in stability between positions was found. Fourth, it was found that the dominant arm had significantly greater instability of the shoulder joint than the non-dominant arm for attackers and centers, but no significant difference was found for setters and liberos. This study comparatively analyzed the muscle strength ratios of the external/internal rotations and dominant/non-dominant arms, which can determine the stability of the shoulder joints between female professional volleyball playing positions that engage in jumps and spikes using only the dominant hand and positions that do not.

• International journal of steel structures
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• v.18 no.4
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• pp.1153-1166
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• 2018

This paper was concerned with the nonlinear analysis on the overall stability of H-type honeycombed composite column with rectangular concrete-filled steel tube flanges (STHCC). The nonlinear analysis was performed using ABAQUS, a commercially available finite element (FE) program. Nonlinear buckling analysis was carried out by inducing the first buckling mode shape of the hinged column to the model as the initial imperfection with imperfection amplitude value of L/1000 and importing the simplified constitutive model of steel and nonlinear constitutive model of concrete considering hoop effect. Close agreement was shown between the experimental results of 17 concrete-filled steel tube (CFST) specimens and 4 I-beams with top flanges of rectangular concrete-filled steel tube (CFSFB) specimens conducted by former researchers and the predicted results, verifying the correctness of the method of FE analysis. Then, the FE models of 30 STHCC columns were established to investigate the influences of the concrete strength grade, the nominal slenderness ratio, the hoop coefficient and the flange width on the nonlinear stability capacity of SHTCC column. It was found that the hoop coefficient and the nominal slenderness ratio affected the nonlinear stability capacity more significantly. Based on the results of parameter analysis, a formula was proposed to predict the nonlinear stability capacity of STHCC column which laid the foundation of the application of STHCC column in practical engineering.

• Korean Journal of Labor Studies
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• v.23 no.1
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• pp.197-220
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• 2017

This paper provides empirical evidence on the impact of increasing import penetration on the job stability of Korean workers. The main results are as follows. First, import penetration negatively affects job stability. If an industry's ratio of imports to total supply increases by 1 percentage point, the turnover probability of workers in that industry increases by 4.5 percentage points. Second, the effect of trade liberalization is not symmetric between imports and exports. Unlike the case of imports, an industry's ratio of exports to output does not have a significant effect on job stability. Third, the impact of import penetration is not uniform across different types of workers. The negative impact is greater for workers in small firms, less educated workers, and those not protected by labor unions.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.20 no.8
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• pp.2721-2730
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• 1996

The present study conducted experimental study of spray combustion to investigate the effect of the inlet conditions of fuel and air on the flame structure, the flame stability and the characteristics of emission in the can-type model of a gas turbine combustor. In the experiment, the diameter of fuel droplet was measured using Malvern particle size analyser and temperatures in the combustion chamber were measured with R-type shielded thermocouple. In addition, flame structure was taken picture with camera and analysed. Gas analyser was also used to analyse the concentration of each components of exhausting gas. The experimental results showed that the flame condition was optimal with swirl number, 0.63 and equivalence ratio, 0.5 for controlling the flame stability, the combustion temperature and the NOx concentration. The present study concluded that both the flame structure and the emission formation were strongly affected by the swirl intensity, which selection was found as an important parameter for either stabilizing flame or lowering the quantity of NOx.

• Journal of the Korean Society of Combustion
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• v.13 no.2
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• pp.7-13
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• 2008

The aim of this work is to identify application of ultra low NOx and CO combustor. To achieve this, we developed the premixed oxidizer-staging combustor using a cyclone flow. Various factors such as equivalence ratio for the combustion condition and swirl type for secondary air injection have been tested experimentally for flame stability and NOx, CO emission characteristics. Before to do this, we had been tested cyclone premixed combustor in advance. it is similar to first combustor of premixed oxidizer-staging combustor. As a result, cyclone premixed flame shows the very high flame stability and low NOx emission. however, it can be identified that there were some problems such as a little high CO emission and thermal resistance of combustor wall. Cyclone premixed oxidizer-staging combustor can resolve those of problems. In our combustor, we can found out optimal condition that the secondary air injection method is swirl type, swirl direction is co-swirl and equivalence ratio of first combustor is 1.3. Quantitatively, we can achieve 10.8 ppm for NOx and 30.2 ppm for CO emissions respectively. Form this result, we can identified that cyclone premixed oxidizer-staging combustor can apply to ultra low NOx and CO combustor.