• 제목/요약/키워드: Specific surface are

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폐암 바이오마커 검출용 나노SPR 바이오센서 (Nano SPR Biosensor for Detecting Lung Cancer-Specific Biomarker)

  • 장은윤;염세혁;엄년식;한정현;김형경;신용범;강신원
    • 센서학회지
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    • 제22권2호
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    • pp.144-149
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    • 2013
  • In this research, we developed a biosensor to detect lung cancer-specific biomarker using Anodic Aluminum Oxide (AAO) chip based on interference and nano surface plasmon resonance (nanoSPR). The nano-porous AAO chip was fabricated $2{\mu}m$ of pore-depth by two-step anodizing method for surface uniformity. NanoSPR has sensitivity to the refractive index (RI) of the surrounding medium and also provides simple and label-free detection when specific antibodies are immobilized to the Au-deposited surface of nano-porous AAO chip. To detect the lung cancer-specific biomarker, antibodies were immobilized on the surface of the chip by Self Assembled Monolayer (SAM) method. Since then lung cancer-specific biomarker was applied atop the antibodies immobilized layer. The specific reaction of the antigen-antibody contributed to the change in the refractive index that cause shift of resonance spectrum in the interference pattern. The Limit of Detection (LOD) was 1 fg/ml by using our nano-porous AAO biosensor chip.

국산 카올린의 흡착성에 관한 연구(II) - 분체학적 고찰 (Studies on the Adsorptive Properties of Korean Kaolin (II) - Micromeritic Study of Korean Kaolin)

  • 이계주
    • 약학회지
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    • 제29권4호
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    • pp.176-182
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    • 1985
  • As a part of the studies on adsorptive properties of Korean halloysite clays, Hadong white clays of premium grade were examined for geometric pore structured by mercury porosimetry and for specific surface areas by nitrogen adsorption according to the BET procedure. Three size fractions of the native clay sample were derived from passage BS #100, #200 and #325 meshes, respectively. Several parameters lhus observed in relation to the pore structures are shown below: 1. The size fraction of BS #100, #200 and #325 show internal pore volumes of 25.3, 30.2 and $35.0m^2g^{-1}$, respectively. 2. In the distribution curves of the cumulative pore volume against pore diameter, it has been shown that the larticle sizes, the steeper the distribution over the larger ranges of pore diameters. The converse is true the smaller particles. 3. Internal pore areas increase with decrease in pore sizes. It follows that the pores having diameters of $\leq$0.1$\mu\textrm{m}$ are responsible for more than 90% of the total pore area. 4. The behaviour of nitrogen adsorption can be best described by BET type IV isotherm. Further, the hysteresis loops of the adsorptiondesorption curves become narrower with decresing particle sizes. 5. The specific surface areas observed for the fractions of BS #100, BS #200 and BS #325 are 34.6, 35.4 and 43.2m $^2g^{-1}$, respectively. and the calcined clay of BS #325 has a specific surface area near $30.4m^2g^{-1}$.

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A Study of the Optimum Pore Structure for Mercury Vapor Adsorption

  • Kim, Byung-Joo;Bae, Kyong-Min;Park, Soo-Jin
    • Bulletin of the Korean Chemical Society
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    • 제32권5호
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    • pp.1507-1510
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    • 2011
  • In this study, mercury vapor adsorption behaviors for some kinds of porous materials having various pore structures were investigated. The specific surface area and pore structures were studied by BET and D-R plot methods from $N_2$/77 K adsorption isotherms. It was found that the micropore materials (activated carbons, ACs) showed the highest mercury adsorption capacity. In a comparative study of mesoporous materials (SBA-15 and MCM-41), the adsorption capacity of the SBA-15 was higher than that of MCM-41. From the pore structure analysis, it was found that SBA-15 has a higher micropore fraction compared to MCM-41. This result indicates that the mercury vapor adsorptions can be determined by two factors. The first factor is the specific surface area of the adsorbent, and the second is the micropore fraction when the specific surface areas of the adsorbent are similar.

Characterization of Surface Properties of $BaTiO_3$ Powder by XPS

  • Chun, Myoung-Pyo;Cho, Jung-Ho;Kim, Byung-Ik
    • 한국분말야금학회:학술대회논문집
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    • 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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    • pp.678-679
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    • 2006
  • The effects of particle size on the surface properties of hydro-thermally synthesized barium titanate powders were investigated by means of particle size analysis, specific surface area, SEM, zeta potential and XPS. Particle sizes were measured by laser light scattering and are in the range of 150 to 1100nm. Zeta potential increased with increasing particle size and it was large minus value in the range of particle size from 500 to 900nm, which seems to be related with the dissolution of $Ba^{2+}$ ion in these particle sizes from the analysis of surface properties by XPS.

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SEM Tribosystem에 의한 CVD TiN막의 미시적 마모 특성 평가 (Evaluation of Microscopic Wear Characteristics for CVD TiN Coatings with SEM Tribosystem)

  • 문봉호
    • 한국표면공학회지
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    • 제37권3호
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    • pp.137-145
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    • 2004
  • This study surveys the microscopic wear of CVD TiN coatings in repeated sliding, using the SEM Tribosystem as in-situ system. According to the research, the depth of wear groove and the specific wear amount are changed by the transition of the microscopic wear mode. This investigation leads to the fact that the change of wear characteristics produces the transition of the wear mode. In this survey, four modes are observed for CVD TiN coatings with the thickness of 1.6$\mu\textrm{m}$: ploughing, powder formation, flake formation and coating delimitation. The microscopic wear properties is quantitatively evaluated in terms with the microscopic wear mode and the specific wear amount. These relationships prove that the observation of wear modes with a SEM Tribosystem is useful to evaluate wear properties.

GIS를 이용한 해안단구 지형면 분류 기법 연구 - 감포지역을 사례로 - (Development of the GIS Method for Extracting a Specific Geomorphic Surface of Coastal Terrace at Gampo Area, Southeastern Coast in Korea)

  • 박한산;윤순옥;황상일
    • 대한지리학회지
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    • 제36권4호
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    • pp.458-473
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    • 2001
  • 지형면 분류도는 지형학 연구에 있어서 가장 기본적인 자료이다 최근가지 이루어지고 있는 항공사진, 지형도 및 현지조사에 의한 지형면 분류 방법은 많은 시간과 높은 숙련도를 요구하며, 항공사진 획득에도 어려움이 있다. 현재 우리나라는 수치지도가 거의 완성되었으므로. GIS를 이용하여 해안단구 지형이 갖는 해발고도와 경사도의 특성을 정량적으로 분석하면, 적합한 지형면을 찾아낼 수 있다. 본 연구에서는 이미 전통적인 방법에 의해 해안단구 연구가 다수 이루어진 한국 남동해안 경주시 감포읍 지역에서, GIS를 이용하여 보다 효율적이고 객관적인 해안단구 지형면 분류 기법을 제시하였다. 이를 위하여 해안단구 지형면 분류 과정을 설계하였으며, 지형면 분류에 적합한 분류요인을 선정하고, 최적분류기준을 추출하여 지형면을 분류한 후, 부합을 및 오류율을 통하여 이러한 방법에 대한 효용성과 문제점을 검토하였다.

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다이아몬드 입자에 형성된 중간층이 다이아몬드 공구 성능에 미치는 영향 (Effect of Intermediate Layer Coated Diamond Particles on Performance of Diamond Tool)

  • 손경식;이정훈;최용제;정우창;정원섭
    • 한국표면공학회지
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    • 제46권5호
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    • pp.216-222
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    • 2013
  • In order to improve the performance of electrodeposited diamond-nickel composite, surface modification of diamond particles was carried out using powder immersion reaction assisted coating (PIRAC). Titanium and chromium were selected as coating elements, which are known as carbide former. With respect to the powder elements, various phases were formed on diamond; metallic Ti and TiC for Ti powder, $Cr_3C_2$ for Cr powder, and TiC and $Cr_3C_2$ for Ti-Cr mixed powder. Surface modified diamond particle showed higher specific surface area, especially Ti coating induced considerable increase of specific surface area. The increase of specific surface area suggests increase of surface roughness, and that was confirmed by surface observation using FE-SEM. In addition, wear properties of diamond-nickel composite including surface modified diamonds were improved, and Ti coated diamond showed the highest performance. The wear property of diamond-nickel composite is dependent on adhesion strength between diamond particle and nickel layer. Therefore, surface modification of diamond particle by PIRAC increasing surface roughness is effective to improve the properties of diamond-nickel composite.

얇은 layer가 존재하는 접촉표면의 열적거동에 대한 연구 (A Study on the Thermal Behaviour of Layered Solids in Sliding Contacts)

  • 안효석
    • Tribology and Lubricants
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    • 제5권2호
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    • pp.42-47
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    • 1989
  • The thermal behaviour of layerd solids, typified in practice by surface coated materials, is evaluated for the specific case of a fast moving heat source. This is intended to represent the particular instance of solids in sliding contact and the consequences of friction. The finite difference method has been utilised to establish the temperature distributions at the surface and also the sub-surface region for coating materials which are either less conductive or more conductive than the substrate to which they are attached. The effects of variation in layer thickness, and also the load, speed and friction coefficient, are evaluated.

Immobilized Small Sized Manganese Dioxide Sand in the Remediation of Arsenic Contaminated Water

  • Tiwari, Diwakar;Laldawngliana, C.;Lee, Seung-Mok
    • Environmental Engineering Research
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    • 제19권1호
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    • pp.107-113
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    • 2014
  • Small sized manganese dioxide particles are immobilized onto the surface of sand by the wet impregnation process. The surface morphology of the solid, i.e., immobilized manganese dioxide natural sand (IMNS) is performed by taking scanning electron microscope images and characterized by the X-ray diffraction data. The specific surface area of the solid is obtained, which shows a significant increase in the specific surface area obtained by the immobilization of manganese dioxide. The $pH_{PZC}$ (point of zero charge) is found to be 6.28. Further, the IMNS is assessed in the removal of As(III) and As(V) pollutants from aqueous solutions under the batch and column operations. Batch reactor experiments are conducted for various physicochemical parametric studies, viz. the effect of sorptive pH (pH 2.0-10.0), concentration (1.0-25.0 mg/L), and background electrolyte concentrations (0.0001-0.1 mol/L $NaNO_3$). Further, column experiments are conducted to obtain the efficiency of IMNS under dynamic conditions. The breakthrough data obtained by the column experiments are employed in non-linear fitting to the Thomas equation, so as to estimate the loading capacity of the column for As(III) and As(V).

멀티 리간드의 특이적 상호작용이 입자-세포간 상호작용에 미치는 영향 (Effect of Specific Interaction of Multi-Ligands on the Specific Interaction between Particle and Cell)

  • 윤정현;이세영
    • 대한의용생체공학회:의공학회지
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    • 제43권2호
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    • pp.94-101
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    • 2022
  • Recent advancement of micro/nano technology enables the development of diverse micro/nano particle-based delivery systems. Due to the multi-functionality and engineerability, particle-based delivery system are expected to be a promising method for delivery to the target cell. Since the particle-based delivery system should be delivered to the various kinds of target cell, including the cardiovascular system, cancer cell etc., it is frequently decorated with multiple kinds of targeting molecule(s) to induce specific interaction to the target cell. The surface decorated molecules interact with the cell surface expressed molecule(s) to specifically form a firm adhesion. Thus, in this study, the probability of adhesion is estimated to predict the possibility to form a firm adhesion for the multi-ligand decorated particle-based delivery system.