• Title/Summary/Keyword: Spatial dependent

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Phase Transitions in Cells and the Structure of Chromatins (세포에서의 상전이와 크로마틴 구조)

  • Kim, Hajin;Yoo, Jejoong
    • Vacuum Magazine
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    • v.5 no.1
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    • pp.13-17
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    • 2018
  • Phase transition is not unique to solid state systems or homogeneous molecular systems but it is also observed in highly heterogeneous biological systems. Phase transition and phase separation in cells are recently being found to be central to many biological functions by temporarily and locally controlling the storage and exchange of certain proteins and RNAs. There are also clues suggesting them to be playing pivotal roles in the spatial organization of chromosomes into topological domains and its time-dependent control. Here we introduce early efforts to explain at the molecular level how the spatiotemporal organization of chromosomes are programmed and modulated by the sequence and chemical modifications of the DNA. Continuing works may provide a physical framework to understand the molecular level control of chromosome structure and dynamics that determine the epigenetic state and the fate of the cells.

Optical Modeling for Polarization-dependent Optical Power Dissipation of Thin-film Organic Solar Cells at Oblique Incidence

  • Kim, Jungho;Jung, Sungyeop;Jeong, Inkyung
    • Journal of the Optical Society of Korea
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    • v.16 no.1
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    • pp.6-12
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    • 2012
  • We present the optical models and calculation results of thin-film organic solar cells (OSCs) at oblique incidence of light, using the transfer matrix method. The simple expression for the optical power dissipation is derived at oblique incidence for s- and p-polarized light. The spatial distribution of the electric field intensity, the optical power density, and the optical power dissipation are calculated in both s- and p-polarized light with respect to the incidence angle. We identify how the light absorption efficiency for p-polarized light becomes relatively larger than that for s-polarized light as the incidence angle increases.

Characterization of the Spatial Distribution of Fracture System at the Rock Block Scale in the Granitic Area (화강암지역의 암반블록규모 단열체계 분포특성 연구)

  • 김경수;배대석;김천수
    • Tunnel and Underground Space
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    • v.12 no.3
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    • pp.198-209
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    • 2002
  • To assess deep geological environment for the research and development of hish-level radioactive waste disposal, six boreholes of 3" in diameter were installed in two granitic areas. An areal extent of the rock block scale in the study sites was estimated by the lineament analysis from satellite images and shaded relief maps. The characterization of fracture system developed in rock block scale was carried out based on the acoustic televiewer logging in deep boreholes. In the Yuseong site, the granite rock mass was divided into the upper and lower zones at around -160m based on the probabilistic distribution characteristics of the geometric parameters such as orientation, fracture frequency, spacing and aperture size. Since the groundwater flow is dependent on the fracture system in a fractured rock mass, the correlation of the fracture frequency and cumulative aperture size to the hydraulic conductivity was also discussed.

Numerical Simulation of Unsteady Inviscid Waves by Spectral Method

  • Lee, Jin-Ho;Chun, Ho-Hwan
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2000.04a
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    • pp.140-145
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    • 2000
  • The spectral method which is composed of an eigenfunction expansion of free modes in the wave number domain is used to produce two dimensional unsteady inviscid wave simulation such as progressive waves in a numerical pneumatic wave tank. A spatial and time dependent free surface elevation and the potential are calculated by integrating ODE derived from fully nonlinear kinematic and dynamic free surface boundary condition at each time step. The nonlinear characteristics in the waves by this method were notable as increasing wave steepness. This method is very useful and powerful in terms of saving computational time caused by rapid convergence exponentially with increasing number of nodes, even preserving accurate numerical results. Moreover, it will given us many possibilities to apply to naval and ocean engineering fields.

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Applications of Stokes Eigenfunctions to the Numerical Solutions of the Navier-Stokes Equations in Channels and Pipes

  • Rummler B.
    • 한국전산유체공학회:학술대회논문집
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    • 2003.10a
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    • pp.63-65
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    • 2003
  • General classes of boundary-pressure-driven flows of incompressible Newtonian fluids in three­dimensional (3D) channels and in 3D pipes with known steady laminar realizations are investigated respectively. The characteristic physical and geometrical quantities of the flows are subsumed in the kinetic Reynolds number Re and a parameter $\psi$, which involves the energetic ratio and the directions of the boundary-driven part and the pressure-driven part of the laminar flow. The solution of non-stationary dimension-free Navier-Stokes equations is sought in the form $\underline{u}=u_{L}+U,\;where\;u_{L}$ is the scaled laminar velocity and periodical conditions are prescribed for U in the unbounded directions. The objects of our numerical investigations are autonomous systems (S) of ordinary differential equations for the time-dependent coefficients of the spatial Stokes eigenfunction, where these systems (S) were received by application of the Galerkin-method to the dimension-free Navier-Stokes equations for u.

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Efficient Meshfree Analysis Using Stabilized Conforming Nodal Integration for Metal Forming Simulation

  • Han, Kyu-Taek
    • Journal of Advanced Marine Engineering and Technology
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    • v.34 no.7
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    • pp.943-950
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    • 2010
  • An efficient meshfree method based on a stabilized conforming nodal integration method is developed for elastoplastic contact analysis of metal forming processes. In this approach, strain smoothing stabilization is introduced to eliminate spatial instability in Galerkin meshfree methods when the weak form is integrated by a nodal integration. The gradient matrix associated with strain smoothing satisfies the integration constraint for linear exactness in the Galerkin approximation. Strain smoothing formulation and numerical procedures for path-dependent problems are introduced. Applications of metal forming analysis are presented, from which the computational efficiency has been improved significantly without loss of accuracy.

Dynamic Direct and Indirect Buckling Characteristics of Arch by Running Response Spectrum (연속 응답 스펙트럼 분석에 의한 아치의 동적 직접 및 간접 좌굴 특성)

  • Yun, Tae-Young;Kim, Seung-Deog
    • 한국공간정보시스템학회:학술대회논문집
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    • 2004.05a
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    • pp.161-168
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    • 2004
  • The dynamic instability of snapping phenomena has been studied by many researchers. Few papers deal with dynamic buckling under loads with periodic characteristics, and the behavior under periodic excitations is expected to be different from behavior under STEP excitations. We investigate the fundamental mechanisms of the dynamic instability when the sinusoidally shaped arch structures are subjected to sinusoidally distributed excitations with pin-ends. The mechanisms of dynamic indirect snapping of shallow arches are especially investigated under not only STEP function excitations but also under sinusoidal harmonic excitations, applied in the up-and-down direction. The dynamic nonlinear responses are obtained by the numerical integration of the geometrically nonlinear equation of motion, and examined by Fourier spectral analysis in order to get the frequency-dependent characteristics of the dynamic instability for various load levels.

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Transient stochastic analysis of nonlinear response of earth and rock-fill dams to spatially varying ground motion

  • Haciefendioglu, Kemal
    • Structural Engineering and Mechanics
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    • v.22 no.6
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    • pp.647-664
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    • 2006
  • The main purpose of this paper is to investigate the effect of transient stochastic analysis on nonlinear response of earth and rock-fill dams to spatially varying ground motion. The dam models are analyzed by a stochastic finite element method based on the equivalent linear method which considers the nonlinear variation of soil shear moduli and damping ratio as a function of shear strain. The spatial variability of ground motion is taken into account with the incoherence, wave-passage and site response effects. Stationary as well as transient stochastic response analyses are performed for the considered dam types. A time dependent frequency response function is used throughout the study for transient stochastic responses. It is observed that stationarity is a reasonable assumption for earth and rock-fill dams to typical durations of strong shaking.

Targeted Memory Reactivation can Enhance Memory Consolidation during Sleep (표적 기억 재활성화로 수면 중 기억 강화 증진 시키기)

  • Cyn, Jaegong
    • Sleep Medicine and Psychophysiology
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    • v.24 no.2
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    • pp.79-85
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    • 2017
  • Targeted memory reactivation (TMR) is a method whereby cues associated with previous learning are used to externally reactivate aspects of this learning. Research findings demonstrate that TMR can be a useful tool to enhance memory consolidation during sleep in both animals and humans, especially in the declarative/spatial domain. Neurocognitive processing during sleep with covert cueing via auditory or olfactory stimulation can benefit memory storage. These beneficial effects on memory consolidation during sleep are associated with the activation of memory-related brain areas. The purpose of the present review is to provide a short overview of the findings of studies that adopted the TMR method of sleep-dependent memory consolidation and to suggest the potential applications of TMR in variable areas.

EVALUATION OF NUMERICAL APPROXIMATIONS OF CONVECTION FLUX IN UNSTRUCTURED CELL-CENTERED METHOD (비정렬 셀 중심 방법에서 대류플럭스의 수치근사벙법 평가)

  • Myong H.K.
    • Journal of computational fluids engineering
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    • v.11 no.1 s.32
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    • pp.36-42
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    • 2006
  • The existing numerical approximations of convection flux, especially the spatial higher-order difference schemes, in unstructured cell-centered finite volume methods are examined in detail with each other and evaluated with respect to the accuracy through their application to a 2-D benchmark problem. Six higher-order schemes are examined, which include two second-order upwind schemes, two central difference schemes and two hybrid schemes. It is found that the 2nd-order upwind scheme by Mathur and Murthy(1997) and the central difference scheme by Demirdzic and Muzaferija(1995) have more accurate prediction performance than the other higher-order schemes used in unstructured cell-centered finite volume methods.