• Title/Summary/Keyword: Space biology

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Radiation Biology in Space; DNA Damage and Biological Effects of Space Radiation

  • Ohnishi, Takeo;Takahashi, Akihisa;Ohnishi, Ken
    • Journal of Photoscience
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    • v.9 no.3
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    • pp.37-40
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    • 2002
  • Astronauts are constantly exposed to space radiation at a low-dose rate during long-tenn stays in space. Therefore, it is important to determine correctly the biological effects of space radiation on human health. Space radiations contain various kinds of different energy particles, especially high linear energy transfer (LET) particles. Therefore, we have to study the relative biological effectiveness (RBE) of space radiation under microgravity environment which may change RBE from a stress for cells. Furthermore, the research about space radiation might give us useful information about birth and evolution of life on the earth. We also can realize the importance of preventing the ozone layer from depletion by use of exposure equipment to sunlight at International Space Station (ISS).

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From Cell Biology to Biotechnology in Space

  • Cogoli, Augusto
    • Animal cells and systems
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    • v.4 no.3
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    • pp.195-200
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    • 2000
  • In this article I discuss the main results of our research in space biology from the simple early investigations with human Iymphocytes in the early eighties until the projects in tissue engineering of the next decade on the international space station ISS. The discovery that T Iymphocyte activation is nearly totally depressed in vitro in 0g conditions showed that mammalian single cells are sensitive to the gravitational environment. Such finding had important implications in basic research, medicine and biotechnology. Low gravity can be used as a tool to investigate complicated and still obscure biological process from a new perspective not available to earth-bound laboratories. Low gravity may also favor certain bioprocesses involving the growth of tissues and thus lead to commercial and medical applications. However, shortage of crew time and of other resources, lack of sophisticated instrumentation, safety constraints pose serious limits to biological endeavors in space laboratories.

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Future Opportunities for life Science Programs in Space

  • Hiroki Yokota;Sun, Hui-Bin;George M. Malacinski
    • Animal cells and systems
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    • v.4 no.3
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    • pp.239-243
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    • 2000
  • Most space-related life science programs are expensive and time-consuming, requiring international cooperation and resources with trans-disciplinary expertise. A comprehensive future program in "life sciences in space" needs, therefore, well-defined research goals and strategies as well as a sound ground-based program. The first half of this review will describe four key aspects such as the environment in space, previous accomplishments in space (primarily focusing on amphibian embryogenesis), available resources, and recent advances in bioinformatics and biotechnology, whose clear understanding is imperative for defining future directions. The second half of this review will focus on a broad range of interdisciplinary research opportunities currently supported by the National Aeronautics and Space Administration (NASA), National Institute of Health (NIH), and National Science Foundation (NSF). By listing numerous research topics such as alterations in a diffusion-limited metabolic process, bone loss and skeletal) muscle weakness of astronauts, behavioral and cognitive ability in space, life in extreme environment, etc., we will attempt to suggest future opportunities.

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The conditions and principles of the 'Bionik' space design on the basis of the consilient horizon of biology and architecture (생물학과 건축의 통섭적 지평에 기초한 비오닉 공간디자인의 조건 및 원리)

  • Lee, Ran-Pyo
    • Korean Institute of Interior Design Journal
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    • v.20 no.5
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    • pp.68-77
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    • 2011
  • In this research it is concentrated first of all on the attempts to reconstruct the historical context of the idea for the space design based on the natural construction and to re-appropriate il critically to the present context. Sequentially in the areas of philosophy, biology, neuroscience, and architecture it has been variously discussed on the problems about the synthesis of biology and techniques. In the context of the consilience of biology and technique Werner Nachtigall, who has intended to shed light on the morphological principles in the natural construction, founded the 'Bionik', which is different from the bionics or the biomechanics that are oriented to the imitation of natural forms. The space design that is on the basis of the Bionik treats organisms as a functional whole. Therefore the Bionik space design follows two kinds of principle such as the principle of analogy and the principle of optimization. After all the understanding of the consilience of nature and technique for Nachtigall and Bionik designers tends toward the explication of the complex process in which the human perceptions, the environment, and the phenomenal techniques are united together, and this complex process is associated with the space design based on the Bionik.

A CLINICOSTATISTICAL STUDY OF FASCIAL SPACE INFECTIONS OF THE ORAL AND MAXILLOFACIAL REGION (구강 악안면 영역의 근막간극 감염증에 관한 임상 통계학적 연구)

  • Ahn, Shin-Young;Kim, Su-Gwan;Kim, Hak-Kyun;Park, Chul-Min
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.2
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    • pp.162-168
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    • 2007
  • Oral and maxillofacial infection is the oldest and most common disease in human history. The infection ranges from the low-grade infection that only requires minimal treatment to the high-grade and life-threatening fascial space infection. In this study, the data on oral and maxillofacial infections were analyzed to aid in the diagnosis and treatment, and to predict the prognosis. This report was based on data from 831 patients with oral and maxillofacial infection (394 males and 437 females) who were hospitalized in the Department of Oral and Maxillofacial surgery of Chosun University Dental Hospital from January 1998 to May 2005. The ratio of males to females was 0.9:1. By age, patients between 60 and 70 years old were the greatest in number (17.1%), while only 5.9% of the patients were between 10 and 20 years old. The most common cause of infection was odontogenic origin (84.4%), followed by post-extraction infection (6.2%), unknown (5.9%), and trauma (3.5%). The most common fascial space involved was the buccal space (39.4%), followed by the canine (20.6%), submandibular (15.9%), pterygomandibular (9.5%), submental (7.6%) and sublingual (2.8%) space. The number of the involved fascial space was one (75.2%), two (19.8%), or more than three (5.0%). In terms of the treatment duration, the hospitalization period of 6 to 10 days was the greatest in number (49.9%). All patients had uneventful recovery without major complication. There are statistically significant correlations between age and treatment period, and the involved space and treatment period, but no correlations between the variables of sex and treatment.

CORRECTION OF DENTAL MIDLINE DEVIATION BY MEANS OF SPACE SUPERVISION (Space supervision을 이용한 치성 정중선 변위의 교정)

  • Kim, Su-Youn;Choi, Young-Chul;Park, Jae-Hong;Choi, Seong-Chul;Kim, Gwang-Chul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.34 no.4
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    • pp.700-708
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    • 2007
  • A midline deviation is divided into three types, such as a skeletal midline deviation, a dental midline deviation, and a combination. Among them, the midline deviation which appear in the early mixed dentition without any skeletal problem can be managed differently by the stage of dental development. The location of the permanent incisors can be improved without using artificial force in consideration of the condition of the space, the eruption timing or the eruption path of the adjacent permanent teeth in early mixed dentition, especially when the permanent incisors are erupting. Therefore, the space supervision technique, which can have the teeth align themselves utilizing physiologic events such as sequence or timing of the eruption of permanent teeth, can be an alternative to orthodontic movement. This case report describes midline deviation improvement by space supervision.

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Ultrastructural Studies on the Oogenesis of the Pine moth, Dendrolimus spectabilis (Lasiocampidae) II. Vitelline Membrane and Chorion Formation (솔나방(Dendrolimus spectabilis) 난소의 미세구조 II. 난황막 및 난각형성과정)

  • Kim, Ji-Hyun;Kim, Jeong-Sang;Kim, Woo-Kap
    • Applied Microscopy
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    • v.24 no.4
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    • pp.52-60
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    • 1994
  • The developing ovarian oocyte of Dendrolimus spectabilis has been studied by using electron microscopical techniques. After yolk formation the vitelline membrane was laid down in the intercellular space between the follicle cell and the oocyte. But before the vitelline membrane formation the granules with high electron density that the vitelline membrane precusor are observed in the follicle cell. At the late vitellogenesis stage these granules were transported into the intercellular space between the follicle cells and the oocyte. These granules fuse to each other and larger bodies which eventually produce the vitelline membrane. The vitelline membrane was distinguished into the light inner and dark outer membrane. Next the chorion was laid down. It was apparent that the chorion was laid down in the intercellular space immediately adjacent to the vitelline membrane, and that it was formed by the follicle cells only.

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Study on the Systematical Features of Small Space Design in Ecology (소규모 공간의 생태학에 근거한 시스템 특성 연구)

  • Cheon, Byoung-Woo
    • Korean Institute of Interior Design Journal
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    • v.21 no.5
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    • pp.77-84
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    • 2012
  • Single formative language created by the standardization of industrial society carries a cell constructive aspect. Such space structural form made gigantic buildings, which has a symbolism as an independent object. Such space shows a morphological symbolism by public preference but it did not establish essential meaning of a shape or concentrated relation. In this regard, this paper tries to show organic similarity of structural formality of small commercial space (patterned space), which was made by the continuity of concentrated patterns not an object of dualistic unit features. Therefore, this study analyzed the cultural, commercial and public space based upon systematical concept and features. Systematical space formality that makes multilateral relation between human, environment and a thing is a concentrated view point by relational features not by the cluster displayed by hierarchical features. Systematical space of small patterned space emphasized its appropriateness of expansion and creating diversified spaces unlike gigantic symbolic buildings.

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Thioredoxin in the Periplasmic Space of Escherichia coli as a Physiological Electron Donor to Periplasmic Thiol Peroxidase, p20

  • Cha, Mee-Kyung;Kim, Il-Han
    • BMB Reports
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    • v.32 no.2
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    • pp.168-172
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    • 1999
  • We previously reported that a novel thiol peroxidase (p20) from Escherichia coli is a distinct periplasmic peroxidase that detoxifies hydroperoxides together with glutathione or thioredoxin. Until now, there was no experimental evidence for the presence of thioredoxin (Trx) in the periplasmic space. In an attempt to confirm the physiological function of p20 as a thiol peroxidase supported by Trx in the periplasmic space, we have purified a Trx activity from the periplasmic space of Escherichia coli and identified the Trx as the same protein as the cytoplasmic Trx. The presence of Trx in the periplasmic space of Escherichia coli suggests that p20 is a unique extracellular Trx-linked thiol peroxidase.

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A Study on Using of Biodiversity Database for Learning of Biodiversity (생물다양성 학습을 위한 생물다양성 DB 활용에 관한 연구)

  • Ahn Bu-Young;Cho Hee-Hyung;Park Jae-Hong
    • Proceedings of the Korea Contents Association Conference
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    • 2005.11a
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    • pp.428-432
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    • 2005
  • This paper has studied the concept and technical factors of e-Learning system to which we intend to apply domestic biodiversity information. This article describes how we analyzed and designed the e-learning system to serve biodiversity information as e-Learning contents. It would be useful for the public and students if this information are organized and provided as e-learning contents especially in our country which has well-established network infrastructure considering the limited land space. It is expected that the establishment of e-Learning system based on this proposed design will help students and public to access and team biodiversity on cyber space.

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