• Journal of Ecology and Environment
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• 제32권4호
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• pp.249-256
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• 2009

The rare endemic plant, Smilax wightii, is generally distributed in shola forests at high altitudes in Nilgiri Biosphere Reserve, the Western Ghats, southern India. To determine the ecological status of the species, we surveyed 11 major shola forests in that region. S. wightii has a limited distribution in all sholas (frequency value of < 13%). The density of the species is generally around $15/100\;m^2$ in the sholas except in Thiashola where it occurred at a density of 40 individuals/$100\;m^2$. The density of S. wightii was generally greater in the margins of the shoals, while the interior forests contained fewer individuals per unit area. The basal cover occupied by this species ranged between 2246 and $3144\;mm^2/100\;m^2$. The importance value index for S. wightii was >2 in all shoals, which indicates that the species occupies an important position in the lower stratum of shola forests of Nilgiri Biosphere Reserve.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1519-1524
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• 2012

Background: Human papillomavirus (HPV) infection is the main cause of cervical cancer. Limited epidemiologic data of HPV prevalence are available for women attending hospitals in southern China. This study aimed to evaluate the profiles of HPV infection and cytology status in gynecological outpatients in Chaozhou City. Methods: A total of 2833 eligible women were enrolled. The HPV GenoArray test was used for HPV detection and genotyping. Nearly one half of the HPV positive women received liquid-based cytology test. Logistic regression analysis was performed to assess the predictable effects of age and genotype for categories of abnormal cytology. Results: The prevalence of overall, high-risk, and low-risk HPV infection were 24.5%, 19.5% and 8.4%, respectively. A U-shaped age-specific prevalence curve was observed in overall HPV and high-risk HPV, but not in low-risk HPV, which declined with age increasing. The 6 most common high-risk HPV type in descending order, were types 52, 16, 58, 18, 68, and 33. Age and HPV genotype were both important determinants of abnormal cytology incidence, the older women (>45 years) and those infected with HPV type 16 and/or 18 having the highest risk for abnormal cytology. Conclusion: Our findings support the hypothesis that second-generation HPV prophylactic vaccines including HPV-52 and -58 may offer higher protection for women residing in Chaozhou and neighboring cities in Guangdong.

• 환경생물
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• 제40권1호
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• pp.1-10
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• 2022

기후변화로 인한 지구온난화는 강수량과 기온에 영향을 주며, 다양한 종들의 서식지와 생물다양성에 상당한 영향을 줄 수 있다. 최근 국제 교류의 증가와 기후변화 등의 원인으로 국내로 새롭게 유입되어 정착하는 외래식물이 증가하고 있지만, 기후변화가 이들 외래식물의 국내 분포에 어떤 영향을 주는지에 대한 연구는 부족한 실정이다. 본 연구는 침입외래식물 큰망초(C. sumatrensis)의 현재 분포와 생물기후 변수를 활용하여 RCPs 기후변화 시나리오에 따른 적합 서식지 분포 변화를 예측하였다. 큰망초는 현재 우리나라 남부 지방에서 제한된 분포를 보이고 있으며, 이들의 분포에는 가장 건조한 분기의 평균기온(bio09), 가장 더운 달의 최고기온(bio05), 등온선(bio03)이 영향을 미치는 것으로 나타났다. 기후변화 시나리오에 따라 큰망초의 미래 적합 서식지 면적은 증가할 것으로 전망되었다. 큰망초와 같은 침입외래종의 분포 변화는 자생식물의 생존을 위협할 수 있으며 생태계 교란을 일으킬 수 있다. 따라서 기후변화에 따른 외래종 분포에 대한 연구는 자생식물뿐만 아니라 생물다양성 보전에 중요한 데이터로 활용될 수 있으며, 향후 서식지 복원과 생물자원을 관리하기 위한 정책자료로 활용될 수 있다.

• 한국지역지리학회지
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• 제21권2호
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• pp.242-258
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• 2015

본 연구는 수도권 실버타운의 공간적 분포 특성을 살펴보았고, 수도권 실버타운에 거주하고 있는 노인들을 대상으로 심층 면담을 실시하여 실버타운에 대한 인식을 알아보았다. 최근에는 가족과의 교류가 용이하며, 의료시설과 접근성이 좋은 도심이나 도시 근교 지역을 선호하는 노인들이 증가함에 따라 수도권에 실버타운이 집중 분포하고 있다. 이들 시설은 주로 서울의 북쪽과 경부 고속도로를 축으로 한 경기도의 남쪽에 위치하고 있다. 따라서 이용자들이 실버타운을 선택할 때 시설의 위치와 접근성이 중요하게 작용한다는 점을 알 수 있었다. 실버타운에서 노인들은 가사 노동에서 해방되어 의미 있는 일을 하면서 여생을 보낼 수 있고, 사회적 계층이 유사한 사람들과 원만하게 교류하며 긍정적인 자아정체감을 가질 수 있다. 이러한 측면에서 80세 이상의 이용자들은 실버타운을 집으로 인식하고 뿌리내림하고 있는 경우가 많았다. 반면에 60~70대의 비교적 젊은 노인들은 실버타운에 입소하여 자신만의 고유한 특성이나 자기결정권이 제한되는 것에 불편을 느끼고 다른 주거 공간으로 이주하는 것을 고려하기도 하였다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2012년도 학술발표회
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• pp.20-25
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• 2012

New Zealand suffers from regular floods, these being the most common source of insurance claims for damage from natural hazard events in the country. This paper describes the origin and distribution of the largest floods in New Zealand, and describes the systems used to monitor and predict floods. In New Zealand, broad-scale heavy rainfall (and flooding), is the result of warm moist air flowing out from the tropics into the mid-latitudes. There is no monsoon in New Zealand. The terrain has a substantial influence on the distribution of rainfall, with the largest annual totals occurring near the South Island's Southern Alps, the highest mountains in the country. The orographic effect here is extreme, with 3km of elevation gained over a 20km distance from the coast. Across New Zealand, short duration high intensity rainfall from thunderstorms also causes flooding in urban areas and small catchments. Forecasts of severe weather are provided by the New Zealand MetService, a Government owned company. MetService uses global weather models and a number of limited-area weather models to provide warnings and data streams of predicted rainfall to local Councils. Flood monitoring, prediction and warning are carried out by 16 local Councils. All Councils collect their own rainfall and river flow data, and a variety of prediction methods are utilized. These range from experienced staff making intuitive decisions based on previous effects of heavy rain, to hydrological models linked to outputs from MetService weather prediction models. No operational hydrological models are linked to weather radar in New Zealand. Councils provide warnings to Civil Defence Emergency Management, and also directly to farmers and other occupiers of flood prone areas. Warnings are distributed by email, text message and automated voice systems. A nation-wide hydrological model is also operated by NIWA, a Government-owned research institute. It is linked to a single high resolution weather model which runs on a super computer. The NIWA model does not provide public forecasts. The rivers with the greatest flood flows are shown, and these are ranked in terms of peak specific discharge. It can be seen that of the largest floods occur on the West Coast of the South Island, and the greatest flows per unit area are also found in this location.

• 한국자원식물학회지
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• 제30권2호
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• pp.176-190
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• 2017

한반도는 동아시아에서 동백나무군강(난온대 낙엽활엽수림)의 최북단 지역이다. 총 40 개의 입지에서 생태학적으로 정의된 야생상의 자생 차나무 개체군에 대한 식생자료가 수집되었다. 우점 상관에 따라 식분을 구분하고, Z.-M. 학파의 식물사회학적 방법에 따라 현지 식생조사와 종조성에 따라 식물군락을 기재하였다. 식생 유형에 따라 생활형, 신귀화식물, 식생지리분포, 고유성 등을 포함하는 생태식물상 특성을 분석하였다. 자생개체군 분포지의 최고해발은 대구시 팔공산(해발 390 m)이었고 최고위도는 익산시 함라산(latitude $36^{\circ}$ 03' 33'')이었다. 대륙성 기후가 우세한 한반도에서의 차나무 자생개체군은 해양성 기후가 우세한 일본에 비하여 수평적 수직적으로 모두 낮은 분포를 보였다. 대부분의 자생개체군은 인간간섭을 받아온 입지에 위치하였고, 자생개체군의 북한계 분포 확장의 동인으로 인간의 도움이 지목되었다. 자생개체군의 군락지리학적 분포는 난온대와 냉온대 남부 저산지대에 제한되었다. 본 연구를 통해 한국에서 차나무 자생개체군의 실체가 확인되었고, 내동성이 높은 유전 자원이라는 관점에서 한반도 자생개체군의 장기생태연구가 요구되었다.

• 수산해양기술연구
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• 제29권1호
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• pp.1-10
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• 1993

In order to investigate the environmental properties of set net grounds located in the coastal waters of Yeosu, oceanographic observations on the fishing grounds were carried out by the training ship of Yeosu Fisheries University from Jun. 1988 to Dec. 1990. The resultes obtained are summarized as follows; 1) The water mass in the fishing grounds were divided into the inner water (29.50-31.00$\textperthousand$), the mixed water (31.10-32.70$\textperthousand$) and the offshore water (32.70-34.30$\textperthousand$) according to the distribution of salinity from T-S diagram plotted all salinity data observed from Jun. 1988 to Dec. 1990. In spring the mixing water prevailed and in summer the inner and mixing water. But in autumn and winter the mixing and offshore waters prevailed. 2) The inner water which was formed by land water from the river of Somjin and the precipitation in the Yeosu district flowed southerly along the coast of Dolsando and spread south-easterly in the vicinity of Kumodo. The inner water and offshore water which supplied from the vicinity of Sorido and Yokchido formed the thermal front and halofront. 3) As the mixing water flowing from the western sea of Cheju to the southern coast of korea was low in temperature, the water mass of low temperature which appeared at the offshore bottom of Sorido in summer was considered not to be the Tsushima warm current. 4) As vertical mixing was made frequently in spring, autumn and winter, the differences in temperature and salinity between surface and bottom was respectively small. In summer, however, the mixing was not made because of the inner water expanded offshore through the space between surface and 10m layer and so a thermocline of $2.0^{\circ}C$/10m and halocline of 4.0$\textperthousand$/10m respectively in vertical gradient was formed. 5) In the vicinity of Dolsando and Kum a water low in salinity prevailed, but in the vicinity of Namhaedo and YoKchido the reverse took place. The inner and mixing waters formed at these arease was limited to the observation area not to spread widely.

• 한국지역지리학회지
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• 제8권4호
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• pp.468-479
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• 2002

태백 산지는 대체로 냉량하고 습한 편이지만, 강수량은 지역적으로 많은 차이를 나타내고 있다. 이와 같은 기후지형 환경과 관련하여 태백산지의 지형 및 토양환경은 기반암의 유형에 따라서 차이를 보인다. 북부의 금강산과 설악산 같은 화강암 분포 지역은 절리밀도의 차이를 반영하는 풍화 성향 때문에 암괴 노출이 심한 산지를 이루며, 미시령 일대의 편마암 분포 지역은 전사면이 흙으로 덮여있고 상대적으로 식생밀도가 높은 곳이다. 중부에서는 암괴 노출이 심한 타지역의 화강암산지와는 달리 박토상태지만 대체로 전사면이 흙으로 덮여있다. 이는 이 지역이 눈이 많고 서릿발 작용이 활발하여 화강암을 얇게나마 풍화시킬 수 있었기 때문이다. 남부에서는 급사면의 뾰족한 봉우리와 좁고 깊은 협곡을 이루는 석회암산지 및 완만한 사면지역의 여러 가지 용식지형이 발달한다. 이 지역에는 초본류나 관목류들이 연속성이 높게 분포하여 박토상태인 토양을 잘 보전하고 있다.

• Journal of Genetic Medicine
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• 제3권1호
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• pp.29-32
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• 1999

The Apolipoprotein E type 4 allele (ApoE ${\varepsilon}4$) is genetically associated with the common late onset familial and sporadic forms of Alzheimer's disease. The BchE-k variant, which is the common variant of the BchE gene, has been reported to show allelic association with AD in subjects who are also carriers of the ${\varepsilon}4$ allele of the ApoE, especially in subjects over the age of 75. This study was performed to evaluate the distribution of the ApoE and the BchE genotypes in the healthy and AD groups and to evaluate the synergy between the BchE-k variant and the ApoE ${\varepsilon}4$ in AD. The ApoE and the BchE genotypes were determined in DNA samples from 610 healthy people and 60 LOAD patients by using ARMS by standard agarose gel electrophoresis. The effect of the ApoE ${\varepsilon}4$ was closely related to AD(p<0.05). A comparison between the AD patients and the healthy individuals, both with the ${\varepsilon}4$ allele, indicated an interaction between the BchE-k and the ApoE ${\varepsilon}4$(p<0.05). The association of the BchE-k with AD was limited to carriers of the ApoE ${\varepsilon}4$ allele, among whom the presence of the BchE-k gave an odds ratio of AD 3.48 (95% C.I. 1.3-9.2). Therefore, these results suggested that further evidence of an association between the ApoE ${\varepsilon}4$ and LOAD, and the BchE-k acts in synergy with the ApoE ${\varepsilon}4$ as a susceptibility gene for AD.

• BMB Reports
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• 제57권2호
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• pp.71-78
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• 2024

Melanoma is one of the most aggressive skin tumors, and conventional treatment modalities are not effective in treating advanced melanoma. Although immunotherapy is an effective treatment for melanoma, it has disadvantages, such as a poor response rate and serious systemic immune-related toxic side effects. The main solution to this problem is the use of biological materials such as hydrogels to reduce these side effects and amplify the immune killing effect against tumor cells. Hydrogels have great advantages as local slow-release drug carriers, including the ability to deliver antitumor drugs directly to the tumor site, enhance the local drug concentration in tumor tissue, reduce systemic drug distribution and exhibit good degradability. Despite these advantages, there has been limited research on the application of hydrogels in melanoma treatment. Therefore, this article provides a comprehensive review of the potential application of hydrogels in melanoma immunotherapy. Hydrogels can serve as carriers for sustained drug delivery, enabling the targeted and localized delivery of drugs with minimal systemic side effects. This approach has the potential to improve the efficacy of immunotherapy for melanoma. Thus, the use of hydrogels as drug delivery vehicles for melanoma immunotherapy has great potential and warrants further exploration.