• Transactions on Control, Automation and Systems Engineering
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• v.2 no.1
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• pp.69-75
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• 2000

The aim of the work described in this paper is to develop a complex underground acoustic system which detects and localizes the origin of an underground hammering sound using an array of hydrophones located about 100m underground. Three different methods for the sound localization will be presented, a time-delay method, a power-attenuation method and a hybrid method. In the time-delay method, the cross correlation of the signals received from the array of sensors is used to calculate the time delays between those signals. In the power-attenuation method, the powers of the received signals provide a measure of the distances of the source from the sensors. In the hybrid method, both informations of time-delays and power-ratios are coupled together to produce better performance of position estimation. A new acoustic imaging technique has been developed for improving the hybrid method. This new acoustic imaging method shows the multi-dimensional distribution of the normalized cost function, so as to indicate the trend of the minimizing direction toward the source location. For each method the sound localization is carried out in three dimensions underground. The distance between the true and estimated origins of the source is 28m for a search area of radius 250m.

• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.103-108
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• 1999

The aim of the work described in this paper is to develop a complex underground acoustic system which detects and localizes the origin of an underground hammering sound using an array of hydrophones located about loom underground. Three different methods for the sound localization will be presented, a time-delay method, a power-attenuation method and a hybrid method. In the time-delay method, the cross correlation of the signals received from the array of sensors is used to calculate the time delays between those signals. In the power-attenuation method, the powers of the received signals provide a measure of the distances of the source from the sensors. In the hybrid method, both informations of time-delays and power-ratios are coupled together to produce better performance of position estimation. A new acoustic imaging technique has been developed for improving the hybrid method. This new acoustic imaging method shows the multi-dimensional distribution of the normalized cost function, so as to indicate the trend of the minimizing direction toward the source location. For each method the sound localization is carried out in three dimensions underground. The distance between the true and estimated origins of the source is 28m for a search area of radius 250m.

• Journal of Biomedical Engineering Research
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• v.29 no.2
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• pp.107-113
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• 2008

We introduce a rotating-gantry-based x-ray micro-tomography system to be used for small animal imaging studies. It has the zoom-in imaging capability for high resolution imaging of a local region inside the animal subject without any contrast anomalies arising from truncation of the projection data. With the sliding mechanism mounted on the rotating gantry holding the x-ray source and the x-ray detector, we can control the magnification ratio of the x-ray projection data. By combining the projection data from the large field of view (FOV) scan of the whole animal subject and the projection data from the small FOV scan of the region of interest, we can obtain artifact-free zoomed-in images of the region of interest. For the acquisition of x-ray projection data, we use a $1248{\times}1248$ flat-panel x-ray detector with the pixel pitch of 100 mm. It has been experimentally found that the developed system has the spatial resolution of up to 121p/mm when the highest magnification ratio of 5:1 is applied to the zoom-in imaging. We present some in vivo rat femur images to demonstrate utility of the developed system for small animal imaging.

• Journal of information and communication convergence engineering
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• v.13 no.4
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• pp.270-274
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• 2015

In this paper, we propose an improved framework to analyze an N-ocular imaging system under fixed constrained resources such as the number of image sensors, the pixel size of image sensors, the distance between adjacent image sensors, the focal length of image sensors, and field of view of image sensors. This proposed framework takes into consideration, for the first time, the defocusing effect of the imaging lenses according to the object distance. Based on the proposed framework, the N-ocular imaging system such as integral imaging is analyzed in terms of depth resolution using two-point-source resolution analysis. By taking into consideration the defocusing effect of the imaging lenses using ray projection model, it is shown that an improved depth resolution can be obtained near the central depth plane as the number of cameras increases. To validate the proposed framework, Monte Carlo simulations are carried out and the results are analyzed.

• Journal of Radiation Protection and Research
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• v.29 no.4
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• pp.231-236
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• 2004

An imaging plate(IP) detector, a two-dimensional digital radiation detector that can acquire image of radioactivity distribution in a sample, has been applied in many fields; for industrial radiography, medical diagnosis, X-ray diffraction test, etc. In this study, the possibility of IP detector to be used lot measuring radioactivity of sample is explored using its high sensitivity, higher spatial resolution, wider dynamic range and screen uniformity for several kinds radiations. First, the IP detector is applied to measure the surface uniformity for area source. Surface uniformity is measured rapidly and nondestructively by measuring the radioactivity distribution of common standard area source$(^{241}Am)$. Next, the IP is employed to study the possibility of measuring an extremely low-level activity of environmental sample. For this study the screen uniformity, shield effect of background radiation, linear dynamic range and fading effect of the IP detector is investigated. The potato, banana, radish and carrot samples are chosen to measure ultra low-level activity of $^{40}K$ isotope. The efficiency calibration of IP detector is carried out using the standard source.

• Journal of the Microelectronics and Packaging Society
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• v.21 no.4
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• pp.25-31
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• 2014

Bioimaging has advanced the field of nanomedicine, drug delivery, and tissue engineering by directly visualizing the dynamic mechanism of diagnostic agents or therapeutic drugs in the body. In particular, wide-field, planar, near-infrared (NIR) fluorescence imaging has the potential to revolutionize human surgery by providing real-time image guidance to surgeons for target tissues to be resected and vital tissues to be preserved. In this review, we introduce the principles of NIR fluorescence imaging and analyze currently available NIR fluorescence imaging systems with special focus on optical source and packaging. We also introduce the evolution of the FLARE intraoperative imaging technology as an example for image-guided surgery.

• Bulletin of the Korean Chemical Society
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• v.35 no.3
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• pp.938-940
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• 2014

This paper discusses a coherence-gated three-dimensional imaging system based on photorefractive holography, which was applied to imaging through turbid media with a view to developing biomedical instrumentation. A rapid response photorefractive device doped with 2,4,7-trinitro-9-fluorenylidene malononitrile was used to generate the hologram grating. The estimated depth resolution was $20{\mu}m$, which corresponds to the coherence length of the light source. In this coherence imaging system, tomographic imaging of a 3-dimensional object composed of a $50{\mu}m$ thick cylindrical layer was achieved. The proposed coherence imaging system using an organic photorefractive material can be used as an optical tomography system for biological applications.

• Journal of Biomedical Engineering Research
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• v.20 no.2
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• pp.165-172
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• 1999

An enhancement technique for phase dependent image contrast in MRI(Manetic Resonance Imaging) is proposed. Because the method can enhance inherent phase contrast it is suited for susceptibility imaging and flow imaging where intravoxel phase is a source of image contrast. In this paper, applying external phase in the voxel enhances phase contrast. The external phase is generated by a tailored RF pulse so that one can control the phase contrast and even produces phase only contrast. Signal intensity due to both inherent phase and external phase is analyzed and the proposed technique is applied to a susceptibility effect only imaging and a flow effect only imaging. To verify the proposed technique, computer simulations are performed and their results are given.

• Journal of Biomedical Engineering Research
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• v.42 no.3
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• pp.116-124
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• 2021

It is important to differentiate between the target tissue (or organ) and the rest of the tissue before incision during surgery. And when it is necessary to preserve the differentiated tissues, the blood vessels connected to the tissue must be preserved together. Various non-invasive medical imaging methods have been developed for this purpose. We aimed to develop a medical imaging system that can simultaneously apply fluorescence imaging using indocyanine green (ICG) and laser speckle contrast imaging (LSCI) using laser speckle patterns. We designed to collect images directed to the two cameras on a co-axial optical path and to compensate equal optical path length for two optical designs. The light source used for fluorescence and LSCI the same 785 nm wavelength. This system outputs real-time images and is designed to intuitively distinguish target tissues or blood vessels. This system outputs LSCI images up to 37 fps through parallel processing. Fluorescence for ICG and blood flow in animal models were observed throughout the experiment.

• Journal of ILASS-Korea
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• v.26 no.4
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• pp.212-218
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• 2021

The present study aims to develop the Surface Plasmon Resonance (SPR) imaging system facilitating the real-time measurement of the concentration of evaporating binary mixture droplet (BMD). We introduce the theoretical background of the SPR imaging technique and its methodology for concentration measurement. The SPR imaging system established in the present study consists of a LED light source, a polarizer, a lens, and a band pass filter for the collimated light of a 589 nm wavelength, and a CCD camera. Based on the Fresnel multiple-layer reflection theory, SPR imaging can capture the change of refractive index of evaporating BMD. For example, the present study exhibits the visualization process of ethylene glycol (EG)-water (W) BMD and measures real-time concentration change. Since the water component is more volatile than the ethylene glycol component, the refractive index of EG-W BMD varies with its mixture composition during BMD evaporation. We successfully measured the ethylene glycol concentration within the evaporating BMD by using SPR imaging.