Background: Ulcerative colitis (UC) is a commonly encountered large intestine disease in the contemporary world that terminates into colorectal cancer; therefore, the timely treatment of UC is of major concern. Panax ginseng Meyer is an extensively consumed herbal commodity in South East Asian countries, especially Korea. It exhibits a wide range of biologically beneficial qualities for almost head-to-toe ailments in the body. Epimedium koreanum Nakai (EKN) is also a widely used traditional Korean herbal medicine used for treating infertility, rheumatism, and cardiovascular diseases. Materials and methods: Separately the anti-inflammatory activities of both red ginseng extracts (RGEs) and EKNs had been demonstrated in the past in various inflammatory models; however, we sought to unravel the anti-inflammatory activities of the combination of these two extracts in dextran sulfate sodium (DSS)-induced ulcerative colitis in mice model because the allopathic remedies for UC involve more side effects than benefits. Results: Our results have shown that the combination of RGE + EKN synergistically alleviated the macroscopic lesions in DSS-induced colitic mice such as colon shortening, hematochezia, and weight loss. Moreover, it restored the histopathological lesions in mice and decreased the levels of proinflammatory mediators and cytokines through the repression of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP-3) expression. In vitro, this combination also reduced the magnitude of nitric acid (NO), proinflammatory mediators and cytokine through NF-κB and mitogen-activated protein kinase (MAPK) pathways in RAW 264.7 mouse macrophage cells. Conclusion: In the light of these findings, we can endorse this combination extract as a functional food for the prophylactic as well as therapeutic treatment of UC in humans together with allopathic remedies.
Humans are provided with a wide range of public benefits from ecosystems and agricultural ecosystems, but the establishment of the horticulture complex could be a space that hampers the public function of the agricultural ecosystem. In this study, we sought to focus the function of landscape creation of agricultural landscape and tried to analyze the landscape of the horticulture complex. Therefore, This study aims to suggest ways to build a greenhouse complex which is being indiscreetly introduced in the agriculture landscape through environmentally-friendly manner and minimize the function of the ecosystem service. We divided the greenhouse complex into two categories of Plastic Greenhouse(v) and Glass Greenhouse(g), and compared them to the Netherland and Japan counterparts. Each image of research areas was selected by 3 pics and polled by a total of 101 people. The results of the Evaluation of Landscape Image are as shown in the figure. Netherland Glass Greenhouse scored 1.80 in terms of 'Neat' which is one of the given 15 adjectives. Study results shows that Korean Plastic Greenhouse landscapes need to endeavor Japanese vinly greenhouses and Dutch glasshouses. Consequently, an analysis on the elements of landscapes including green area, variant elements, separation distance is essential in order to improve our country's greenhouse complex landscapes. In this regard, continuous research is required to improve rural landscapes and harmonize large-scale horticultural facilities into the existing agricultural ecosystem.
Journal of Korean Society of Environmental Engineers
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v.30
no.12
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pp.1273-1280
/
2008
This study sought to establish the optimum operating condition for the recovery of caustic (NaOH) solution from mercerization in textile process. As main factors, the silt density index (SDI) evaluation of ceramic membrane for the application of nanofiltration/reverse osmosis (NF/RO) membrane, the recovery yield measurement of caustic solution for the application of polymeric membrane, the optimum condition of chemical cleaning for the membrane regeneration, the optimum removal condition of total organic carbon (TOC), turbidity, color, and the permeate flux of ceramic membrane/polymeric membrane combined process were investigated. As results, ceramic ultrafiltration (UF) in the first step and nanofiltration (NF) in the second step were found to be suitable for the removal of total suspended solid (TSS), residual organics, turbidity including color, and the recovery of caustic solution from caustic wastewater stream in mercerization process. When only the ceramic UF membrane was used, the rejection efficiency of both of TSS and turbidity was more than 99.0%, and the color and TOC were rejected about 74.7% and 49.2%, respectively. Meanwhile, the combined membrane precess of UF and NF membranes showed even more efficient removal abilities and thus more than 99.9% of TSS and turbidity, 87.7% of color, and 78.2% of TOC were removed. In particular, 91.3% of NaOH was successfully recovered with 83.7% of total volume in the combined membrane process. With this regard, a clean caustic solution was obtained in a high purity, which can be reused for mercerization process, expecting to offer economical benefits.
Journal of the Institute of Electronics Engineers of Korea SP
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v.44
no.6
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pp.100-110
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2007
When compressed video data is transmitted over error-prone network such as wireless channel, data is likely to be lost, so the quality of reconstructed picture is severely decreased. It is specially so in case that important information such as motion vector or macroblock mode is lost. H.264/AVC standard includes DP as error resilient technique for protecting important information from error in which data is labeled according to its relative importance. But DP technique requires a network that supports different reliabilities of transmitted data. In general, the benefits of UEP is sought by sending multiple times of same packets corresponding to important information. In this paper, we propose MDC technique based on data partitioning technique. The proposed method encodes motion vector of H.264/AVC standard into multiple parts using MDC and transmits each part as independent packet. Even if partial packet is lost, the proposed scheme can decode the compressed bitstream by using estimated motion vector with partial packets correctly transmitted, so that achieving improved performance of error concealment with minimal effect of channel error. Also in decoding process, the proposed multiple description matching increases the accuracy of estimated lost motion vector and quality of reconstructed video.
This paper explores what we call 'the problem of undone social science' by examining the lack of interests in the social, ethical, and legal issues of synthetic biology among social scientists in Korea. This new field of science, which has emerged in the twenty-first century with the promise of solving future problems of energy, food, and disease in the world, has also created a considerable degree of anxiety over the issues of bioethics, biosafety, and biosecurity. From its beginning, therefore, researchers of synthetic biology in Europe and the U.S. have sought to engage social scientists in their projects. Yet scientists and social scientists in Korea have shown no sign of working together to deal with both potential benefits and risks of synthetic biology. Why this silence? What strategic moves would be needed to overcome the structural barrier for their collaboration? Surveying the diverse methodologies developed during and after ELSI (ethical, legal, social implications) experiments, this paper aims to provide three suggestions that might make possible mutually profitable and continuously stimulating dialogues between the two worlds of science and social science: first, institutionalize the ELSI studies on any newly emerging science and technology of concern; second, explore diverse post-ELSI methodologies experimented elsewhere and develop ones that might be applicable best to the Korean situation; and third and perhaps most important, create an intellectual space and a lawful protection for social scientists to exercise their research freedom at the reasonable level and receive a fair review by their peers, not solely by funding agencies and scientific organizations.
Subway station scales are determined by peak predictions. In this study, the purpose behind the installation of a subway is public transportation convenience and public interest, but economic validity is also important. By proving that the scale of the station is excessive with regard to the target station size for Seoul subway Line 5-8, a reasonable plan. can be sought. According to station installation standards, the area of the station under investigation here is out of the service levels by six stages (A~F), and it must be four or more levels (D). The Actual level for the B level is a two-step design. The Actual ratio for over- Peak predictions is only 17.8% on average. The results of measurements of the excess area and determination of the excessive costs were analyzed by subdividing the area and by calculating it based on the B level, finding that it is possible to provide benefits for customers only in the current design, with an area ratio of 16.3%. Given the weight, it was estimated that current conditions can meet the needs of only 18.6% of the current area. Simplifying the scale calculation method of the station, it is convenient, safe, and advantageous to move citizens only if the scale can be streamlined. Then, with a reduced initial investment, maintenance costs during the operation can be reduced.
The pandemic of COVID-19 also affected performing arts business and stimulated 'Untact' performances, which means online streaming of the shows including real-time streaming. This study sought to examine factors to the consumers' acceptance. The research framework was based on the VAM, a revised model of TAM for the ICT products and services. For the research, consumer survey was conducted, where ndependent variables are perceived usefulness, pleasure, technicalty and innovation resistance, and dependent variables are percieved value and acceptance. Smart PLS was used to test the hypothesis. The result shows that the significant factors were percieved usefulness(+), pleasure(+) and innovation resistance(-). The percieved technicalty was not significant, the major reason would be that the digital devices and the internet technology are percieved a commodity these days in Korea. Percieved value was significant factor to acceptance. This study is meaningful because it is about the new phenomenon of 'untact' performance through the VAM methodology and it examined the significant factors to the attitude from the perspective of benefits and costs. There is limit that this study didn't consider old peoples' attitude. It is the reason that the continuous researches are necessary.
This paper summarizes the legal problems and issues raised in relation to generative AI. In addition, we looked at what regulatory discussions individual countries or international organizations have in order to solve or respond to these issues or to minimize the risks posed by generative AI. Infringement of individual basic rights raised by generative AI, the emergence and control of new crimes, monopolization of specific markets and environmental issues are mainly discussed, and although there are some differences in the necessity and direction of regulation, most countries seem to have similar views. Regarding AI, the issues that are currently being raised have been discussed continuously from the beginning of its appearance. Although certain issues have been discussed relatively much, there are some differences between countries, and situations that require consideration of phenomena different from the past are emerging. It seems that regulations and policies are being refined according to the situation of individual countries. In a situation where various issues are rapidly emerging and changing, measures to minimize the risk of AI and to enjoy the utility and benefits of AI through the use of safe AI should be sought. It will be necessary to continuously identify and analyze international trends and reorganize AI-related regulations and detailed policies suitable for Korea.
According to one Medicare report, in the US, total federal spending on health care expends almost 18 percent of the nation's GDP, about double what most industrialized nations spend on health care. And in 2011, Medicare spending reached close to $554 billion, which amounted to 21 percent of the total spent on U.S. health care in that year. Of that $554 billion, Medicare spent 28 percent, or about $170 billion, on patients' last six months of life. So what are the reasons of this high cost in EOL care and its possible solutions? Much spendings of Medicare on End-of-Life care for the terminally ill/chronically ill in the US has led health economics experts to assess the characteristics of the care. Decades of study shows that EOL care is usually supply-sensitive and poor in cost-effectiveness. The volume of care is sensitively depending on the supply of resources, rather than the severity of illness or preferences of patients. This means at the End-of-Life care, the medical resources are being overused. On the other hand, opposed to the common assumption, "The more care the better utility", the study shows that the outcome is very poor. Actually the patient preference and concerns are quite the opposite from what intense EOL care would bring about. This study analyzes the reasons for the supply-sensitiveness of EOL care. It can be resulted from the common misconception about the intense care and the outcome, physicians' mission for patients, lack of End-of-Life Care Decision which helps the patients choose their own preferred treatment intensity. It also could be resulted from physicians' fear of legal liabilities, and the management strategy since the hospitals are also seeking for financial benefits. This study suggests the possible solutions for over-treatment at the End-of-Life resulting from supply-sensitiveness. Solutions can be sought in two aspects, legal implementation and management strategy. In order to implement advance directive properly, active ethics education for physicians to change their attitude toward EOL care and more conversations about end-of-life care between physicians and patients is crucial, and incentive system for the physicians who actively have the conversations with patients will also help. Also, the general education towards the public is also important in the long run, and easy and official advance directive registry system-such as online registry-has to be built and utilized more widely. Alternative strategies in management are also needed. For example, the new strategic cost management and management education, such as cutting unnecessary costs and resetting values as medical providers have to be considered. In order to effectively resolve the problem in EOL care for the terminally ill/chronically ill and provide better experience to the patients, first of all, the misconception and the wrong conventional wisdom among doctors, patients, and the government have to be overcome. And then there should be improvements in systems and cultures of the EOL care.
The Sputnik 1 launching in 1957 made the world recognize the necessity of international regulations on space development and activities in outer space. The United Nations established COPUOS the very next year, and adopted the mandate to examine legal issues concerning the peaceful uses of outer space. At the time, the military sector of the U.S.A. and the Soviet Union were in charge of the space development and they were not welcomed to discuss the prohibition of the military uses of outer space at the legal section in the COPUOS. Although both countries had common interests in securing the freedom of military uses in outer space. As the social and economic benefits derived from space activities have become more apparent, civil expenditures on space activities have continued to increase in several countries. Virtually all new spacefaring states explicitly place a priority on space-based applications to support social and economic development. Such space applications as satellite navigation and Earth imaging are core elements of almost every existing civil space program. Likewise, Moon exploration continues to be a priority for such established spacefaring states as China, Russia, India, and Japan. Recently, Companies that manufacture satellites and ground equipment have also seen significant growth. On 25 February 2012 China successfully launched the eleventh satellite for its indigenous global navigation and positioning satellite system, Beidou. Civil space activities began to grow in China when they were allocated to the China Great Wall Industry Corporation in 1986. China Aerospace Corporation was established in 1993, followed by the development of the China National Space Administration. In Japan civil space was initially coordinated by the National Space Activities Council formed in 1960. Most of the work was performed by the Institute of Space and Aeronautical Science of the University of Tokyo, the National Aerospace Laboratory, and, most importantly, the National Space Development Agency. In 2003 all this work was assumed by the Japanese Aerospace Exploration Agency(JAXA). Japan eases restrictions on military space development. On 20 June 2012 Japan passed the Partial Revision of the Cabinet Establishment Act, which restructured the authority to regulate Japanese space policy and budget, including the governance of the JAXA. Under this legislation, the Space Activities Commission of the Ministry of Education, Culture, Sports, Science, and Technology, which was responsible for the development of Japanese space program, will be abolished. Regulation of space policy and budget will be handed over to the Space Strategy Headquarter formed under the Prime Minister's Cabinet. Space Strategy will be supported by a Consultative Policy Commission as an academics and independent observers. By revoking Article 4 (Objectives of the Agency) of a law that previously governed JAXA and mandated the development of space programs for "peaceful purposes only," the new legislation demonstrates consistency with Article 2 of the 2008 Basic Space Law. In conformity with the principles laid down in the 1967 Outer Space Treaty JAXA is now free to pursue the non-aggressive military use of space. New legislation is the culmination of a decade-long process that sought ways to "leverage Japan's space development programs and technologies for security purposes, to bolster the nation's defenses in the face of increased tensions in East Asia." In this connection it would also be very important and necessary to create an Asian Space Agency(ASA) for strengthening cooperation within the Asian space community towards joint undertakings.
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