• Journal of Chest Surgery
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• 제10권1호
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• pp.98-105
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• 1977

A 36 year old blindman, engineer was admitted with chief complaints of hemoptysis, recurrent sore throat, pyoderma in genital organ, uveitis and thrombophlebitis for 10 years. Above the chief complaints were remission or exacerbation during hospitalization. Physicalexamination showed that left radial, ulnar & brachial pulse was not palpable. No bruit or murmur was obtained over the mass. Neurologic examination revealed no significant finding.On admission, chest P-A showed hen egg sized round & oval compact hazy density on left upper lung field. Bronchogram revealed no pathological finding and Lt. tomogram showed well define large,ovoid mass density in the superior mediastinum. Fluoroscopy finding showed nonpulsatile on left upper lung field. Pre-op. aortography was not taken, under the impression of lung Ca. rule out .sortie aneurysm, exploratory operation was performed through the 2nd intercostal space, Lt. It was performed that the mass was ascending sortie aneurysm of saccular type. Direct aneurysmectomy with multiple figure of eight suture were done without any prosthetic graft. Post-op. control I.V.C graphy showed completely obstruction sign. Postopcontrol aortography revealed good surgical result. Final, histopathological answered non-specific sortie aneurysm, saccular type. Post-op. courses were uneventful except mild neurologic disturbance with subclavian steal syndrome and associated with both lower leg pitting edema due to inferior vena cava obstruction. After op, 3 month later, discharged to home, with big systemic problem. Behcet`s syndrome reviewed with related literatures. The coexistence of mouth and genital ulceration with hypopyon mentioned by hippocrates and described by various workers in the early part of this century was first defined as a syndrome by Behcet in 1937. In 1937 Behcet described a chronic relapsing triple symptom complex of oral ulceration, genital ulceration, and ocular inflammation. The place of the syndrome as part of a systemic disorder in now clearer, and the under lying pathology appears to be a vasculitis. The disease runs a- chronic course, blindness being the greatest disability and control nervous system involvement a cause of death. Thrombophlebitis is fairly frequent, france et al [1951] giving an incidence of 25% and Dowling [1961] 12%, superficial thrombophlebitis migrans and thrombosis of large veins, including venae cavae [Thomas, 1947: Boolukos 1960] are recorded. Little attention has been paid to arterial involvement. Mishima et al. [1961] described resection cf an aortic aneurysm in a 38 year old man with Behcet`s syndorme. Mounsey in a clinicopathological conference described a case [Brit, med. J., 1966] of ruptured aortic aneurysm in Bechcet`s syndrome treated by aorto-iliac graft. Also, Shikano and Oshima et al [1963] recorded two aneyrysm of smaller arteries. Unfrequently, aortic aneurysm was presumed to be secondary to osteomyelitis of the lumber spine, though the possible association between aortic aneurysm and Behcet`s syndrome was raised. A further case is reported here, in which ascending aortic aneurysm with Behcet`s Ds. appeared to form part of this generalized disease. This is a case report of surgical experience of Behcet`s Ds. with ascending aortic aneurysm which had nearly all the typical clinical features. Above mentioned and was reviewed with related literatures.

• 한방재활의학과학회지
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• 제21권2호
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• pp.211-226
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• 2011

Objectives : The purpose of this study is to establish literatural evidence about traditional Korean medical physiotherapy through literatural review. Methods : Applicable paragraphs which were related to the traditional Korean medical physiotherapy were phrased from in "Hwang-je-nae-gyung(黃帝內經)", "Yumun-sa-chin(儒門事親)", "Geum-guei-yo-ryack(金匱要略)", "Eui-hack-ip-mun(醫學入門)", "Gyung-ack-jeon-seo(景岳全書)", "Eui-hack-gang-mock(醫學綱目)", "Dong-eui-bo-gam(東醫寶鑑)" where were archiving of Oriental or Korean medicine literatures. Searched paragraphs were analysed for establishing historical and theoretical bases of Korean medical physiotherapy. Results : 1. Theromtherapy is originated from yu(熨), hot hand, warm, water bath, warm earth, fumigation, lamp, torchlight and brazier. Matching indications are various musculoskeletal pain and diseases, skin diseases such as chronic inflammation, frostbite, gynecological and urogenital diseases such as uterine myoma, lower abdominal pain, metrorrhagia, breast diseases, digestive tract diseases such as vomiting, diarrhea, stomachache and also it treats cardiovascular disease. Other matching indications are sunstroke, rhinorrhea, psycosis and anal pain. And it used helping acupuncture therapy. 2. Cryotherapy is originated from lengfu(冷敷), lengtie(冷貼), cold stone and cold water. Matching indications are various fever disease, skin diseases such as acute inflammation, wound, fever skin disease, otorhinolaryngological diseases such as acute sore throat, otitis, stomatitis, nasal bleeding and contusions, abrasions, burn and dysuria. In addition, it treats extremity coldness, chillness, stomachache caused to accumulate fever. 3. Physiotherapy by circulating meridian system is originated from manipulation such as pushing, massage and beating to therapy point. Matching indications are musculoskeletal diseases such as various muscular pain, heavy sensation, convulsion, urogenital diseases such as dysuria, lower abdomen pain, digestive tract diseases such as stomachache, and paralysis due to blocked meridian system. And other matching indications are psycosis, leprosy, hypoesthesia, acute stroke. In addition it helps other therapy methods. In addition, the power of manipulation classify to strengthen and reduce. 4. Physiotherapy by balancing meridian system is originated from sunshine, magnet, horn, bamboo and tube. Sunshine helps improving self's care and cure inflammatory skin disease. Magnet's matching indications are paralysis, various injuries, abscess, fever and eye disease. Cupping therapy treats to skin diseases and internal diseases such as tuberculosis. Conclusions : Traditional Korean medical physiotherapy was widely used in traditional Korean medicine since ancient time based on the traditional Korean medical principle and anatomical knowledge. With modern physiotherapy and traditional Korean medicine together, effects of treatment are enhanced. And traditional Korean medical physiotherapy is appropriated to world physiotherapy's expectation.

• 미생물학회지
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• 제41권1호
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• pp.53-59
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• 2005

인플루엔자바이러스는 거의 매년 겨울철에 유행을 일으키는 급성 호흡기 질환의 주요한 원인 바이러스중의 하나로 막대한 사회 경제적 손실을 가져온다. 본 실험은 2003-2004절기 동안 $38^{\circ}C$이상의 갑작스러운 발열과 더불어 기침 또는 인후통을 보이는 401명의 인플루엔자의사환자(ILI : Influenza-like illness) 검체로부터 124주의 인플루엔자바이러스를 분리하여 형 및 아형 분석과 그에 따른 유행양상을 분석하였다. 인플루엔자 의사환자 연령별 분포를 살펴보면 20-49세의 성인층의 환자수가 $23\%$로 가장 많았으며, 바이러스 분리율은 7-19세의 학령기에서 $50\%$로 가장 높았다. 분리된 인플루엔자바이러스 124주 중 A/H3N2 type는 83주, Type B는 41주였다. 지역별 인플루엔자 의사환자 발생율은 노원구, 서초구, 강남구의 발생율이 타 지역에 비해 비교적 높았으며 바이러스 분리율은 용산구 $66.7\%$, 강남구 $50.0\%$, 노원구 $39.9\%$, 강북구 $36.8\%$ 서초구 $27.8\%$, 동작구 $21.2\%$ 순이었다. 인플루엔자 의사환자의 예방접종현황조사결과 접종을 받았음에도 불구하고 인플루엔자 의사환자로 보고된 경우가 $40\%$였으며, 접종율은 20-49세 성인층이 가장 높았다. 이와 같은 인플루엔자 실험실 표본감시체계 결과의 분석을 통하여 새로운바이러스형 출현을 감시하며, 현행 예방백신의 효과 및 유행양상을 예측하여 국가 인플루엔자 관리대책을 수립하는데 활용하고자 한다.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1978년도 제12차 학술대회연제 순서 및 초록
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• pp.5.2-6
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• 1978

후두질환은 조기진단 및 치료에 의하여 그 예후가 크게 좌우되며 확진을 위하여는 조직생검이 필수적이다. 저자들은 후두질환의 조기진단에 도움이 되고자 1973년부터 1975년까지 3년간 서울의대부속병원 이비인후과외래에서 간접후두경, 또는 후두직달경하에 후두조직생검을 시행한 142례에 대하여 임상통계적 분석고찰을 시행하였으며, 결과는 다음과 같다. 1. 조직생검례는 총 124례이었으며, 남자 109례(76.8%), 여자 33례(23.2%)이었다. 남여비는 3.3 : 1이었다. 2. 연령별로는 50대, 60대가 각각 41례(28.8%)로 가장 많았으며, 40대(19.7%), 30대(11.2%)의 순이였다. 50대, 60대의 남여비는 각각 7 : 1, 6 : 1이었다. 3. 주소는 사성이 127례(89.4%)로 가장 많았으며, 연하곤란이 7례(4.9%)였고 기타 인후통, 호흡곤란 등이었다. 사성의 발생부터 내원까지의 기간은 평균 8.1개월이었으며 2∼6개월이 56례(44.0%)로 가장 많았고 6개월∼2년이 34례(24%), 2개월 이내가 17례(13.4%)였다. 3연이상은 15례(11.8%)였다. 4. 조직생검부위는 진성대가 76례(53.5%)였으며 가성대가 23례(16.2%), 후두개가 19례(13.3%)였고, 그 외에 발열연골부, 전연합, 성문하역의 순이었다. 5. 조직생검결과는 악성종양이 69례(48.6%), 후두결절 20례(14.0%), 후두유두종 15례(10.5%), 후두결핵 12례(8.4%)였으며, 기타의 양성종양이 15례(10.6%), 비특리성염증이 7례(5.0%)의 순이였다. 6. 악성종양을 의심하였으나 비특리성염증이나 후두결핵등으로 판명된 경우가 13.4%였다.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1981년도 제15차 학술대회연제순서 및 초록
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• pp.14.3-15
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• 1981

상기도에 오는 Midline Granuloma는 비강, 부비동 및 인후두부에 발생하여 국소성 괴저성 염증 및 육아종이 진행성으로 주위조직을 침범하여 결국은 사망을 초래케되는 불치의 병으로 알려져 왔다. 이 질환은 1897년 McBride에 의하여 처음으로 기술되었고, 1933년 Stewart이래 많은 임상적 및 조직학적 연구가 있었다. 그러나 현재까지 그 원인 및 확실한 치료방법이 알려져 있지 않고 있다. 본원에서는 1964년 1월부터 1980년 12월까지 17년간 Midline Granuloma로 진단받고 치료받은 15례에 대한 임상적 관찰과 방사선치료 및 Steroid병용요법으로 치료받은 7례를 분석하여 다음과 같은 결과를 얻었다. 1) 성별 및 연령 : 30세부터 39세사이가 6례 (40%)로 가장 많았으며, 남자 13례 (87%) 여자 2례 (13%)였다. 2) 초발 병변 부위는 비강 및 비중격 부위가 8례 (53%), 인두편도 3례 (20%) 및 인두부 2례 (13%)의 순이었다. 3) 증상으로는 비폐색과 인두통이 각각 6례 (40%)로 가장 많았고, 두통5례(33%), 비루 및 안면 부종이 각각 3례(20%)의 순이었다. 4) 4례에서 균을 검출하였으며 포도상구균 2례, 녹농군 1례, 연쇄상구균이 1례였다. 5) 방사선 치료와 Steroid병용요법을 실시한 7례에서는 전례에서 현재까지 추적 관찰한 결과 재발이나 악화가 없었다. 6) Steroid와 항생제 치료를 받았던 5례중 2례는 사망하였고 3례는 일시적인 증상의 호전을 보였으나 그 후 악화를 보였다.

• 대한기관식도과학회지
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• 제3권2호
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• pp.293-301
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• 1997

The tonsillitis has long been one of the most common disease in the otolaryngologic field. Peritonsillar abscess occurs when bacterial infection of the tonsil spreads to the potential peritonsillar space deep behind the tonsil, and it usually occurs in patients with recurrent tonsillitis or in those with tonsillitis who have been inadequately treated. We studied retrospectively 71 patients who had been diagnosed as acute tonsillitis and 82 patients who had been diagnosed as peritonsillar abscess and had admitted in our department of the Ulsan Dong Kang Hospital from January, 1995 to September, 1997. Especially in the bacteriologic studies, we compared acute tonsillitis and peritonsillar abscess with chronic tonsillitis. The following results were obtained： 1) The sex distributions of acute tonsillitis were 47 males(66%) and 24 females(34%) cases, but 57 males(70%) and 25 females(30%) in cases of peritonsillar abscess. There were predominant in male and frequently affected in second and third decades in 53 cases(76%) of acute tonsillitis and 56 cases(68%) of peritonsillar abscess. 2) It was same found in each season. 3) The duration from onset of symptom to visit in our department was 3.92 days in cases of acute tonsillitis and 5.95 days in cases of peritonsillar abscess in average 4) The major symptoms were sore throat, swallowing difficult. And others were fever, fatigability, dysarthria, trismus, headache, otalgia. 5) Among the 71 cases of acute tonsillitis and 82 cases of peritonsillar abscess, most temperature of patients at visit were 36.6-37.5 $^{\circ}C$ in each 36 cases(51%), 57 cases(70%). 6) In each disease, 35 cases(47%), 45 cases(75%) consisted of single infection and 39 cases(53%), 15 cases(25%) consisted of mixed infection. In acute tonsillitis, 111 strains were isolated from 74 cases, the most common strain was 69 strains(62.2%) of $\alpha$-hemolytic streptococci. In the peritonsillar abscess, 77 strains were isolated from 60 cases, the most common strain was 49 strains(63.6%) of $\alpha$-hemolytic streptococci. In chronic tonsillitis, 563 strains were isolated from 382 cases, the most common strain was 334 strains(50.3%) of $\alpha$-hemolytic streptococci. 7) In acute tonsillitis and peritonsillar abscess, the most common leukocyte levels were reported with 10, 000-15, 000/$\mu$L in 23 cases(32%). The CRP levels were reported with abnormal findings in 61 cases(97%), 63 cases(95%) above 0.3 in each cases.

• 동의생리병리학회지
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• 제36권4호
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• pp.130-137
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• 2022

Due to the coronavirus disease 2019 (COVID-19) pandemic, appropriate management of sequelae and treatment of infectious symptoms became increasingly important healthcare issues. Although the practice guidelines and treatment cases based on the East Asian traditional medicine have been reported, there are rare studies on the use of Korean medicine in Korea. Therefore, this study aimed to present the progress of non-contact Korean medical treatment for infected patients at a local public health center using retrospective chart review. A total of 18 patients were prescribed with 5 days of herbal decoction and medicine extract covered by the national health insurance. With the questionnaire form, the progression and improvement of symptoms before and after treatment were evaluated using the numerical rating scale (NRS), and the treatment satisfaction and opinions were obtained. The symptoms such as cough (5.56±2.23 to 2.89±2.14), sputum (6.11±1,75 to 3.28±2.47), sore throat (6.06±2.70 to 1.47±1.62), anorexia (5.56±2.63 to 1.94±2.21), nausea (3.75±1.71 to 1.17±1.11), diarrhea (3.40±2.63 to 1.50±1.51), chest tightness (4.93±2.46 to 2.29±2.30) and fatigue (6.44±1.79 to 2.67±1.88) all improved according to the NRS, and the satisfaction with herbal medicine treatment on a 5-point Likert scale was 4.24±0.90. No side effects and adverse reactions were reported. Thereupon non-contact Korean medical treatment can be concluded that it effectively reduces the COVID-19 infection mild symptoms in restrictive extent. Since the retrospective data does not include a control group, the more confirmative data is needed by multicenter and large-scale controlled clinical study afterwards.

• 대한본초학회지
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• 제39권3호
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• pp.107-114
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• 2024

Objective : Cicadae Periostracum (CP), which is the discarded shell of the Cryptotympana atrata (Fabricius, 1775), is a recognized component of oriental medicine for treatment sore throat, itching, shock, sedation, edema. However, the safety and toxicity of CP have not yet been established. It has been reported that symptoms of addiction or side effects may occur in patients who take high doses of CP or who are hypersensitive to it. Therefore, we investigated the acute toxicity of an CP extracts in Sprague-Dawley (SD) rats. Methods : To study acute toxicity, five SD rats of each sex per group were treated with CP extracts at single doses of 0, 500, 1000, or 2000 mg/kg administrated by oral gavage, and body weight, clinical signs, and mortality were observed after dosing. At the end of 14-day observation period, all animals were sacrificed and complete hematological and macroscopic examinations were performed. Results : There were no dead animal and test article-related effects on body weight change or the gross finding. No toxicologically significant results were observed between control and treated groups in hematology. Although salivation related to stress at the highest dose was observed in clinical signs immediately after administration, it is considered to have no toxicological significance. Conclusion : As the results, we did not find any adverse effect at the dose levels of 500, 1000, or 2000 mg/kg in rats. The minimal lethal dose was considered to be over 2000 mg/kg body weight in rats.

• 대한한의학회지
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• 제44권4호
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• pp.41-58
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• 2023

Objectives: This retrospective observational study aimed to investigate the efficacy and safety of Cheongpebaedok-tang, a traditional Korean herbal medicine, provided via telemedicine to patients with asymptomatic to mild COVID-19 in Korea. Methods: From February to April 2020, a retrospective analysis investigated COVID-19 patients treated via Korean telemedicine. The study involved asymptomatic to mild cases receiving Cheongpebaedok-tang more than three times, along with continuous Korean medicine care in convalescence. Diagnoses and treatment adhered to the telemedicine guidelines of the Association of Korean Medicine, with varied Cheongpebaedok-tang prescriptions based on symptom severity. Symptom evaluation involved a detailed assessment using a 15-item tool at initial and final sessions. Results: The study included 27 patients, with a mean age of 48.7 ± 2.3 years (mean ± standard error). Patients began self-administering oral Cheongpebaedok-tang for an average of 19.4 ± 1.8 days after the date of COVID-19 diagnosis confirmation and continued the medication for 15.8 ± 1.2 days. The reported side effects of the Cheongpebaedok-tang included palpitations (11.1%), insomnia (7.4%), dizziness (3.7%), and diarrhea (3.7%). All side effects disappeared after adjusting the prescription according to standard treatment guidelines. The occurrence of all COVID-19-related adverse symptoms, except fatigue and myalgia, decreased. Fatigue was the most common chronic symptom persisting after 6 months (51.9%), followed by ocular symptoms (37.0%) and sore throat (22.2%). Conclusions: This study implies Cheongpebaedok-tang may offer a potentially safe, symptom-alleviating approach for managing mild COVID-19 cases via telemedicine, although further comprehensive research is warranted.

• Pediatric Infection and Vaccine
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• 제12권2호
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• pp.114-123
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• 2005

목 적 : 2003년 하반기 우리나라에서 전국적으로 마이코플라즈마 폐렴의 폭발적인 유행을 보였다. 그러나 예년과는 달리 심한 임상경과를 밟거나, 합병증과 폐외 증상을 동반하는 경우가 많이 관찰되었기에 저자들은 본원의 경험을 토대로 2003년 유행했던 마이코플라즈마 폐렴의 임상양상에 대해서 고찰해 보고자 한다. 방 법 : 2003년 8월부터 2004년 4월까지 분당차병원 소아과에 폐렴증상으로 입원한 환아들 중, 입원 후 검사한 혈청 마이코플라즈마 항체가가 1 : 320 이상이거나 1주 간격으로 시행한 항체가가 4배 이상 증가가 있었던 환아 106명을 대상으로 후향적 고찰을 하였다. 결 과 : 총발열기간은 평균 $8.2{\pm}2.7$일, 입원 후 발열기간은 평균 $5.3{\pm}2.0$일이었다. 호흡기 증상으로는 기침(96.2%), 콧물(48.6%), 인후통(39.4%), 호흡곤란(12.3%) 등의 순이었으며 지속기간은 각각 평균 $22.1{\pm}4.8$일, $8.4{\pm}2.1$일, $4.3{\pm}1.2$일, $3.8{\pm}3.4$일 등의 순이었다. 기침이 3개월까지 가는 경우도 소수에서 관찰되었으나, 치료기간과는 상관관계가 없었다. 비호흡기증상으로는 복통(21.9%), 구토(17.1%), 설사(16.2%), 두통(14.4%), 피부발진(5.9%), 관절통(4.9%) 등의 순이었다. 입원기간은 평균 $7.4{\pm}4.3$일이었으며 총치료기간은 $21.6{\pm}11.1$일이었다. 합병증으로 파종성 혈관 내 응고증(2명), 심근염(2명), 관절염(3명), 혈관염(5명), 천식(3명), 급성호흡 부전(1명) 등이 관찰되었다. 결 론 : 2003년 하반기 우리나라에서 유행했던 마이코플라즈마 폐렴은 예년과는 달리 심한 임상경과를 보였고, 적지 않게 합병증을 동반하였다. Mycoplasma pneumoniae 아형의 종류에 따라 임상경과가 심해질 수 있는지는 아직 확실하지 않다. 단지, 다른 바이러스 감염과 동시 감염되는 경우 바이러스성 폐렴의 증세를 악화시키는 것으로 알려져 있다. 이번 유행과 다른 바이러스와 공동감염 관련여부는 본 연구에선 확인할 수 없었다. 소아에서 마이코플라즈마 폐렴이 심한 임상경과를 밟을 수도 있다는 것을 알아야 하겠다.