• 한국식품영양과학회지
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• 제46권1호
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• pp.39-45
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• 2017

본 연구에서는 생산지역별 감초의 물질 표준화를 위해 주요지표성분 중 glycyrrhizic acid를 지표물질로 선정하고 정량분석을 위해 분석법 검증을 수행하였다. 감초의 glycyrrhizic acid의 분석법 검증은 특이성, 직선성, 검출 및 정량한계, 정확성, 정밀성을 구하여 확립하였다. 확립된 분석 방법으로 시험한 국내외 생산지역별 감초의 glycyrrhizic acid 정량 분석 결과 국내산 중에서는 제천산이, 수입산 중에서는 우즈베키스탄산이 각각 16.98, 54.22 mg/g으로 높은 함량을 나타내었다. 또한, 현대인의 심각한 대사질환 중 하나인 당뇨병 예방 및 개선에 효과적인 기능성 천연물 소재를 발굴하고 항당뇨 효과 검증을 위해 생산지역별 감초 에탄올 추출물의 ${\alpha}-glucosidase$ 저해 활성 및 glucose uptake 활성을 평가하였다. ${\alpha}-Glucosidase$ 저해 활성은 국내외 5종 중 제천, 곡성지역의 감초에서 무처리군 대비 높은 저해 활성을 보였고, 우즈베키스탄산은 유의적인 활성이 나타나지 않았다. Glucose uptake 활성의 경우 인슐린 처리를 한 대조군 대비 제천, 영주, 우즈베키스탄 지역의 감초에서 각각 24.19, 27.18, 26.92% 유의적으로 증가함을 확인하였다. 따라서 본 연구의 지표성분 분석, 분석법 검증 결과 및 생리활성 평가는 생산지역별 감초의 물질 표준화 및 품질 평가의 기초자료를 제공하는 데 큰 의미가 있으며, 감초가 대사질환인 당뇨 예방 및 개선에 효과적인 생약식품 소재로의 개발 가능성을 확보하였다. ${\alpha}-Glucosidase$ 저해 활성 및 glucose uptake 활성 평가뿐만 아니라 감초에 함유된 많은 물질연구를 통해 알려지지 않은 활성에 관한 계속된 추후 연구가 필요할 것으로 보인다.

• 한국환경과학회지
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• 제11권5호
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• pp.419-436
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• 2002

The current paper reports on the enhancement of O$_3$, CO, NO$_2$, and aerosols during the Asian dust event that occurred over Korea on 1 May 1999. To confirm the origin and net flux of the O$_3$, CO, NO$_2$, and aerosols, the meteorological parameters of the weather conditions were investigated using Mesoscale Meteorological Model 5(MM5) and the TOMS total ozone and aerosol index, the back trajectory was identified using the Hybrid Single-Particle Lagrangian Integrated Trajectory Model(HYSPLIT), and the ozone and ozone precursor concentrations were determined using the Urban Ashed Model(UAM). In the presence of sufficiently large concentrations of NO$\sub$x/, the oxidation of CO led to O$_3$ formation with OH, HO$_2$, NO, and NO$_2$ acting as catalysts. The sudden enhancement of O$_3$, CO, NO$_2$ and aerosols was also found to be associated with a deepening cut-off low connected with a surface cyclone and surface anticyclone located to the south of Korea during the Asian dust event. The wave pattern of the upper trough/cut-off low and total ozone level remained stationary when they came into contact with a surface cyclone during the Asian dust event. A typical example of a stratosphere-troposphere exchange(STE) of ozone was demonstrated by tropopause folding due to the jet stream. As such, the secondary maxima of ozone above 80 ppbv that occurred at night in Busan, Korea on 1 May 2001 were considered to result from vertical mixing and advection from a free troposphere-boundary layer exchange in connection with an STE in the upper troposphere. Whereas the sudden enhancement of ozone above 100 ppbv during the day was explained by the catalytic reaction of ozone precursors and transport of ozone from a slow-moving anticyclone area that included a high level of ozone and its precursors coming from China to the south of Korea. The aerosols identified in the free troposphere over Busan, Korea on 1 May 1999 originated from the Taklamakan and Gobi deserts across the Yellow River. In particular, the 1000m profile indicated that the source of the air parcels was from an anticyclone located to the south of Korea. The net flux due to the first invasion of ozone between 0000 LST and 0600 LST on 1 May 1999 agreed with the observed ground-based background concentration of ozone. From 0600 LST to 1200 LST, the net flux of the second invasion of ozone was twice as much as the day before. In this case, a change in the horizontal wind direction may have been responsible for the ozone increase.

• 한국환경과학회지
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• 제26권2호
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• pp.183-200
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• 2017

The classification of airflow patterns during high ozone ($O_3$) and $PM_{10}$ episodes on Jeju Island in recent years (2009-2015), as well as their correlation with meteorological conditions according to classified airflow patterns were investigated in this study. The airflow patterns for $O_3$ and $PM_{10}$ were classified into four types (Types A-D) and three types (Types E-G), respectively, using the HYbrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model and synoptic weather charts. Type A was the most dominant airflow pattern for $O_3$ episodes, being characterized by the transport of airflows from urban and industrial areas in China with the highest frequency (about 69%, with a mean of 67 ppb). With regard to the $PM_{10}$ episodes, Type E was the most dominant airflow pattern, and was mostly associated with long distance transport from Asian dust source regions along northwesterly winds, having the highest frequency (about 92%, with a mean of $136{\mu}g/m^3$). The variations in the concentration of $O_3$ and $PM_{10}$ during the study period were clarified in correlation with two pollutant and meteorological variables; for example, the high (low) $O_3$ and $PM_{10}$ concentrations with high (low) air temperature and/or wind speed and vice versa for precipitation. The contribution of long-range transport to the observed $PM_{10}$ levels in urban sites for different airflow patterns (Types E-F), if estimated in comparison to the data from the Gosan background site, was found to account for approximately 87-93% (on average) of its input. The overall results of the present study suggest that the variations in $O_3$ and $PM_{10}$ concentrations on Jeju Island are mainly influenced by the transport effect, as well as the contribution of local emissions.

• 한국산림과학회지
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• 제105권2호
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• pp.208-215
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• 2016

우리나라 자생수종인 정금나무는 낙엽활엽관목으로 열매는 식약용으로 사용되어 왔으나 기능성성분 함량 및 항산화 활성에 관한 연구는 미진한 실정이다. 따라서 본 연구는 국내 자생 정금나무 4집단 24개체의 열매에 대한 형태적 특성, 식물생리활성물질(폴리페놀, 플라보노이드, 안토시아닌) 및 항산화활성을 분석하였다. ANOVA 분석결과 모든 특성들에서 집단 및 개체간의 유의적인 차이가 인정되었다. 총 페놀 함량은 4.40~10.58 mg GAE/g, 총 플라보노이드 함량은 2.02~8.09 mg NE/g, 총 안토시아닌 함량은 232.5~684.3 mg CGE/100g, 환원력은 0.15~1.43, DPPH 자유라디컬 소거능은 400 ppm 농도에서 49.1-97.5% 범위를 각각 나타냈다. 특히, 정금나무 열매의 기능성 성분 함량 및 항산화활성이 국내재배 및 북미산 블루베리에 비해 우수한 것으로 나타나 육종소재 및 기능성 성분 소재로서의 이용 가치가 높은 수종으로 판단된다.

• 한국콘텐츠학회논문지
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• 제12권5호
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• pp.103-112
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• 2012

본 연구는 과학대중화에 있어 중요한 역할을 수행하고 있는 국내 과학전문채널인 'YTN 사이언스'가 시청률, 콘텐츠, 제작비의 부족을 드러내고 있다는 문제인식 하에, 우선 현행 국내 과학전문채널의 프로그램 편성과 운영현황, 홍보 전략을 탐색적으로 확인하였다. 다음으로 미국(디스커버리 채널, 내셔널지오그래픽 채널), 영국(BBC Knowledge), 일본(사이언스채널), 중국(CCTV 10) 등 해외 각국의 과학방송채널 특히, 중요 프로그램들을 분석하여 향후 국내 과학전문채널에 활용 및 접목시킬 수 있는 가능성을 모색하였다. 이러한 현실진단과 해외사례분석을 통해 다양한 시사점을 확인하였으며, 이를 통해 제시될 수 있는 콘텐츠 개발 및 홍보전략은 다음과 같다. 우선 콘텐츠가치 제고를 위한 편성전략의 수정이 필요한 바, 타깃 시청집단과 시청자 라이프스타일을 고려한 편성 재조정, 줄띠편성(Stripping)을 통한 시청습관화 전략, 프라임타임(prime time)대의 전략 프로그램 배치가 필요할 것이다. 다음으로 콘텐츠제작 및 활용전략 측면에서는 콘텐츠 제작의 이중적 전략(지식전달, 흥미전달의 두 분야로의 구분), 프로그램의 대표 캐릭터의 기획과 활용, 한국적 과학기술소재의 선택, SNS와의 전략적 연계, 소재의 다변화와 심층화, OSMU 활성화 전략이 요구될 것이다. 마지막으로 홍보전략 차원에서는 과학관련 행사 개최와 중계방송을 통한 채널 인지도 제고, 잡지 및 단행본 발간 등 인쇄매체로의 확장을 통한 홍보전략 수행, 온라인/모바일 홍보 전략의 강화 등을 제시할 수 있겠다.

• 대한한의학회지
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• 제35권1호
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• pp.157-170
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• 2014

Objectives: The purpose of this study was to develop a standard instrument of diagnosis and assessment for spleen qi deficiency pattern. Methods: Reports published in Korea and China related to spleen qi deficiency pattern were selected. Assessments of selected references were performed to select major symptoms of spleen qi deficiency pattern. Korean translation and review by a Korean linguist were performed to create a draft of [Standard instrument of diagnosis and assessment for spleen qi deficiency (for subject)]. The final [Standard instrument of diagnosis and assessment for spleen qi deficiency (for subject)] was completed after assessment on inclusion or exclusion, on importance of items and on validity of translation by an expert committee, consisting of professors from the National College of Korean Medicine. Results & Conclusions: 1. 14 major symptoms were selected by frequency from 45 references which were related to standard identification of spleen qi deficiency pattern, translated into Korean and reviewed by a Korean linguist. 2. 11 symptoms were selected after assessment on inclusion yes or no by the expert group. Items were listed in order of importance: tiredness of extremities (肢体倦怠), sallow complexion (面色萎黃), reduced appetite (食欲减退), abdominal distension after eating (腹胀食後尤甚), inability to eat (納少), pale tongue and white fur (舌淡苔白), lethargy (神疲), emaciation (消瘦), loose stool (大便溏薄), shortness of breath and reluctance to speak (少氣懶言), and weak pulse (脈緩弱). 3. Final [Standard instrument of diagnosis and assessment for spleen qi deficiency (for subject)] was completed after assessment of translation validity, reflection of individual opinions by the expert committee, and application of weighted value computed from assessment on importance of items.

• 한국항만경제학회지
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• 제23권4호
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• pp.71-90
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• 2007

군산항 물류 기 종점(O/D) 분석결과 군산항 컨테이너화물 유치를 위해 단기적인 방법으로서 내륙운송비절감으로 경쟁력이 있는 전북권 및 충청권의 최적권역 물동량을 확보하고, 대외적으로는 현재 군산항에서 가장 많은 화물을 처리하는 인근 중국 항만과의 교류활성화를 통하여 컨테이너화물을 유치해야 한다. 이를 위해 당장 시급한 것은 수요자들이 군산항을 이용하고자 하는데 느끼는 불편사항을 파악하여 개선함으로서 고객만족서비스를 제공하는 일이다. 이에 따라 본 연구는 군산항을 이용하고 있고 이용을 고려하고 있는 화주와 선사 그리고 물류업체들을 대상으로 실태조사를 실시하여 애로요인을 파악하였다. 실태조사에 나타난 군산항의 가장 큰 문제는 수심을 확보하여 정기선사들이 입.출항하는데 걸림돌이 없도록 하여야 하며, 항만운영, 항만관련제도정비, 항만인프라 등을 개선하여야 한다. 위와 같은 사항이 개선되어 군산항에 컨테이너화물 유치가 활발히 이루어지면 정기선사들이 기항하게 될 것이고, 신규항로가 개설되어 적기에 선적하게 되면 물류비절감에 따라 화주들은 군산항을 이용하게 되어 경쟁력이 확보될 것이다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.339-339
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• 2017

The long grain rice varieties adaptable to South-east Asia tropical regions were tried to develop in Cambodian Agriculture Research and Development Institute (CARDI), Cambodia. The final goal is to develop rice varieties which can culture in diverse environmental conditions of tropical regions of South-east Asia under climate change. We collected and evaluated for agronomic traits of 131 rice germplasm from Cambodia, China, India, Indonesia, Myanmar, Philippines and Vietnam in CARDI. We selected core germplasm including leading varieties of target countries and made 813 F1 cross combinations between leading varieties of each country and promising germplasm of high yield potential, resistance to biotic/abiotic stresses, aromatic rice, and so on. Out of 607 F1s evaluated to heading date, plant type, agronomic traits, and grain type, 106 F1s selected and advanced to F2 populations. 106 F2 populations were evaluated to major agronomic traits, grain type and yield-component traits, and selected 2,560 plants in 62 F2 populations. During six seasons in 2014~2016, the lines of F3 subsequent-generation were cultured a total of 6,256 lines. In yield trial for promising lines in F5 generation, the growth duration from sowing to harvesting was 97~114 days. These lines were 88~129 in number of grain per panicle, an average of 84.6% in the range of 79.3~91.9% in the percentage of ripened grain and 17.5~22.8g in 1000-brown rice weight. The rough rice yields were in the range of 4.33~6.06 ton/ha with an average of 5.23 ton/ha. The yield was increased to 5~47% than Chulsa and 12~41% than IR66. Five lines, KR54-28-1, KR55-14-2, KR57-5-2, KR67-57-2 and KR128-19-1 were 5.33~6.06 ton/ha in rough rice yield. These high yield potential lines would be evaluated to adaptability in Cambodia, Laos, Myanmar and Vietnam during 2017.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.155-155
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• 2017

The long grain rice varieties adaptable to South-east Asia tropical regions were tried to develop in Cambodian Agriculture Research and Development Institute (CARDI), Cambodia. The final goal is to develop rice varieties which can culture in diverse environmental conditions of tropical regions of South-east Asia under climate change. We collected and evaluated for agronomic traits of 131 rice germplasm from Cambodia, China, India, Indonesia, Myanmar, Philippines and Vietnam in CARDI. We selected core germplasm including leading varieties of target countries and made 813 F1 cross combinations between leading varieties of each country and promising germplasm of high yield potential, resistance to biotic/abiotic stresses, aromatic rice, and so on. Out of 607 F1s evaluated to heading date, plant type, agronomic traits, and grain type, 106 F1s selected and advanced to F2 populations. 106 F2 populations were evaluated to major agronomic traits, grain type and yield-component traits, and selected 2,560 plants in 62 F2 populations. During six seasons in 2014~2016, the lines of F3 subsequent-generation were cultured a total of 6,256 lines. In yield trial for promising lines in F5 generation, the growth duration from sowing to harvesting was 97~114 days. These lines were 88~129 in number of grain per panicle, an average of 84.6% in the range of 79.3~91.9% in the percentage of ripened grain and 17.5~22.8g in 1000-brown rice weight. The rough rice yields were in the range of 4.33~6.06 ton/ha with an average of 5.23 ton/ha. The yield was increased to 5~47% than Chulsa and 12~41% than IR66. Five lines, KR54-28-1, KR55-14-2, KR57-5-2, KR67-57-2 and KR128-19-1 were 5.33~6.06 ton/ha in rough rice yield. These high yield potential lines would be evaluated to adaptability in Cambodia, Laos, Myanmar and Vietnam during 2017.

• Asian Pacific Journal of Cancer Prevention
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• 제15권20호
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• pp.8657-8660
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• 2014

Background: Yanting is one of high risk areas for esophageal cancer and the screening program was therefore initiated there. This study was aimed to investigate the dietary behaviors on the risk of esophageal squamous cell carcinoma (ESCC), among the individuals with normal and abnormal esophagus mucosa. Materials and Methods: A frequency matched case-controls study was proposed to estimate the different distribution of dietary behavior between individuals of control, esophagitis and cancer groups. Cancer cases were selected from hospitals. Esophagitis cases and controls were selected from screening population for ESCC. Health workers collected data for 1 year prior to interview, in terms of length of finishing a meal, temperature of eaten food and interval between water boiling and drinking. Chi-square, Kruskal-Wallis tests and unconditional logistic regression model were used to estimate differences and associations between groups. Results: Compared with controls, length of finishing a meal ${\geq}15mins$ was related to a reduced OR for cancer (OR=0.46, 95%CI, 0.22-0.97) and even compared with cases of esophagitis, the OR of cancer was reduced to 0.30 (95%CI, 0.13-0.72). The OR for often eating food at a high temperature was 2.48 (95%CI 1.06, 5.82) for ESCC as compared with controls. Interval between water boiling and drinking of ${\geq}10mins$ was associated with lower risk of cancer: the OR was 0.18 compared with controls and 0.49 with esophagitis cases (p<0.05). Conclusions: Length of eating food ${\geq}15mins$ and interval between water boiling and drinking ${\geq}10mins$ are potentially related to reduced risk of esophageal SCC, compared with individuals with normal and abnormal esophageal mucosa. Recommendations to Yanting residents to change their dietary behaviors should be made in order to reduce cancer risk.