• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2022년도 추계학술대회
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• pp.430-432
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• 2022

오픈액세스, 오픈데이터, 오픈소스 등 과학기술 분야의 오픈사이언스 운동에 대한 최근의 관심 증가에 따라, 공적 자금을 투입한 연구 산출물을 공유하고 활용하려는 움직임이 구체화 및 활성화되고 있다. 이런 흐름에 따라, 최근 국내에서 연구수행의 핵심적인 자원인 연구데이터를 공유하고 활용하는 체제를 구축하고 활성화하려는 많은 노력이 진행되고 있다. 이러한 노력은 주로 연구데이터를 모아서 분야 및 기관별로 모으고 이를 국가 연구데이터 플랫폼인 DataON과 연계하여 검색 및 활용하는 것에 초점을 맞추고 있다. 그러나 선진국에서는 이러한 연구데이터 뿐만 아니라, IaaS, PaaS, SaaS, MLaaS 등 다양한 형태의 연구개발 관련 컴퓨팅 리소스를 공유하고 활용할 수 있는 체제를 구축하고 있다. EOSC(European Open Science Cloud), ARDC(Australian Research Data Commons), CSTCloud(China S&T Cloud) 등이 대표적인 사례라고 할 수 있고 국내에서는 이러한 컴퓨팅 리소스의 공유를 수월하게 수행할 수 있도록, KRDC(Korea Research Data Commons)를 설계하고, 핵심 프레임워크를 개발하고 있다. 본 연구에서는 KRDC의 필요성, 개념, 구성, 향후 계획을 소개한다.

• Earthquakes and Structures
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• 제26권2호
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• pp.97-115
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• 2024

In this paper, a database consisting of the dynamic shear modulus ratio and damping ratio test data of clay obtained from 406 groups of triaxial tests is constructed with the starting area of Xiong'an New Area as the research background. The aim is to study the nonlinear dynamic properties of clay in this area under cyclic loading. The study found that the effective confining pressure and plasticity index have certain influences on the dynamic shear modulus ratio and damping ratio of clay in this area. Through data analysis, it was found that there was a certain correlation between effective confining pressure and plasticity index and dynamic shear modulus ratio and damping ratio, with fitting degree values greater than 0.1263 for both. However, other physical indices such as the void ratio, natural density, water content and specific gravity have only a small effect on the dynamic shear modulus ratio and the damping ratio, with fitting degree values of less than 0.1 for all of them. This indicates that it is important to consider the influence of effective confining pressure and plasticity index when studying the nonlinear dynamic properties of clays in this area. Based on the above, prediction models for the dynamic shear modulus ratio and damping ratio in this area were constructed separately. The results showed that the model that considered the combined effect of effective confining pressure and plasticity index performed best. The predicted dynamic shear modulus ratio and damping ratio closely matched the actual curves, with approximately 88% of the data falling within ±1.3 times the measured dynamic shear modulus ratio and approximately 85.1% of the data falling within ±1.3 times the measured damping ratio. In contrast, the prediction models that considered only a single influence deviated from the actual values, particularly the model that considered only the plasticity index, which predicted the dynamic shear modulus ratio and the damping ratio within a small distribution range close to the average of the test values. When compared with existing prediction models, it was found that the predicted dynamic shear modulus ratio in this paper was slightly higher, which was due to the overall hardness of the clay in this area, leading to a slightly higher determination of the dynamic shear modulus ratio by the prediction model. Finally, for the dynamic shear modulus ratio and damping ratio of the engineering site in the starting area of Xiong'an New Area, we confirm that the prediction formulas established in this paper have high reliability and provide the applicable range of the prediction model.

• Journal of Microbiology
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• 제45권2호
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• pp.105-112
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• 2007

The objective of this study was to analyze the phylogenetic composition of bacterial community in the soil of an earth-cave (Niu Cave) using a culture-independent molecular approach. 16S rRNA genes were amplified directly from soil DNA with universally conserved and Bacteria-specific rRNA gene primers and cloned. The clone library was screened by restriction fragment length polymorphism (RFLP), and representative rRNA gene sequences were determined. A total of 115 bacterial sequence types were found in 190 analyzed clones. Phylogenetic sequence analyses revealed novel 16S rRNA gene sequence types and a high diversity of putative bacterial community. Members of these bacteria included Proteobacteria (42.6%), Acidobacteria (18.6%), Planctomycetes (9.0 %), Chloroflexi (Green nonsulfur bacteria, 7.5%), Bacteroidetes (2.1%), Gemmatimonadetes (2.7%), Nitrospirae (8.0%), Actinobacteria (High G+C Gram-positive bacteria, 6.4%) and candidate divisions (including the OP3, GN08, and SBR1093, 3.2%). Thirty-five clones were affiliated with bacteria that were related to nitrogen, sulfur, iron or manganese cycles. The comparison of the present data with the data obtained previously from caves based on 16S rRNA gene analysis revealed similarities in the bacterial community components, especially in the high abundance of Proteobacteria and Acidobacteria. Furthermore, this study provided the novel evidence for presence of Gemmatimonadetes, Nitrosomonadales, Oceanospirillales, and Rubrobacterales in a karstic hypogean environment.

• 식물분류학회지
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• 제44권3호
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• pp.191-201
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• 2014

동아시아산 황기속의 외부형태학적 특징과 과피, 종피의 해부구조 및 표면 형태를 조사하여 분류학적으로 유용한 형질을 찾고자 하였다. 연구 결과, 황기속의 외부형태, 과피, 종피의 형태 및 해부학적 특징 중 생활사, 소엽의 형태, 꽃차례, 꽃잎의 색, 종자의 색, 과피의 형태, 과피 표면에서 털의 존재유무, 봉선의 구조, 그리고 내과피 층의 두께가 종을 나누는 식별형질로 사용될 수 있음을 확인하였다. 이를 바탕으로 중국에서 황기라는 약재로 사용되어지고 있는 4종의 형태 및 해부학적인 특성을 비교한 결과, 서로 같은 군으로 유집되었다. 한편, 분류학적으로 논쟁이 되고 있는 정선황기와 갯황기에서는 두 분류군간에 형태적 차이점을 발견 할 수 없었다. 따라서 금후 정선황기, 갯황기, A. bhotanensis의 종간 분류학적 처리를 명확히 규명하기 위하여 염기서열 및 분자세포학 수준에서의 연구가 필요하다.

• 동의생리병리학회지
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• 제29권2호
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• pp.143-151
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• 2015

This study was aimed at investigating the syndrome differentiation and herbal medicine of Thromboangiitis Obliterans by reviewing Chinese traditional medicine's journals. The journal search was carried out using China National Knowledge Infrastructure(CNKI) and PubMed from September 2009 to August 2014. Searching key words were the various combination of "Thromboangiitis Obliterans", "traditional chinese medicine", "syndrome differentiation", "herbal medicine". The final selection of 33 studies were selected and summarized by researchers. The syndrome differentiation was classified as yang deficiency, cold syncope and blood stasis. The most frequently herbs were blood-activating and stasis-resolving medicinals.

• 복식
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• 제63권8호
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• pp.125-142
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• 2013

Soek(Xi) was the highest ranked shoe that was worn with the primary formal dress in East Asian countries including ancient Korea and China. This article examined Joseon's Seok as discussed in previous studies, and it explored factors such as the wearers' status, wearing situations, its morphology, its materials, and its colors in the Great Han Empire period (1897~1910), and then extracted three morphological characteristics of the Korean Seok to examine its origin. The results of the study are as follows. For women, the Seok in the Great Han Empire period was worn with Won-sam(圓衫) and No-eui(露衣) as well as Jeok-eui(翟衣), and hence its range of wearing was extensive. Also, red Seok was worn with deep red colored Dae-sam(大衫)-styled Jeok-eui in the Joseon period(1392~1897), and blue Seok with deep blue Jeok-eui in the Great Han Empire period. This suggests the possibility that wearing of deep blue Jeok-eui occurred after 1906 in terms of the use of blue Seok. As for its morphology, its leg-less form was maintained into the late Joseon period, and there were no great changes in its name. The characteristics of the Korean Seok's morphological structure consisted of a shoe leg, the wood-less bottom and pearl ornament. As a result of the examination of the origin of those characteristics, it has been clarified that the form in which Gu, Eok, Jun(純), are attached in the structure with a shoe leg originated from the combination of Hwa(靴) and Li(履) after the two types of shoes were alternately worn in the Song (宋) period. Also, it was confirmed that the woodless bottom appeared between the periods from Wei Jin Northern and Southern Dynasties(魏晉南北朝) to Sui(隋), and the pearl ornament occurred in the Jin(金) period.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5747-5752
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• 2012

Purpose: The main objective of the present study was to evaluate the efficacy and toxicity of concurrent chemoradiotherapy followed by adjuvant chemotherapy compared with concurrent chemoradiotherapy alone in the treatment of locoregionally advanced nasopharyngeal carcinoma. Methods: The search strategy included Pubmed, Embase, the Cochrane Library, China National Knowledge Internet Web, Chinese Biomedical Database and Wanfang Database. We also searched reference lists of articles and the volumes of abstracts of scientific meetings. Randomized controlled trials (RCTs) that compared concurrent chemoradiotherapy followed by adjuvant chemotherapy with concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma were included. Meta-analysis was performed with RevMan 5.1.0. The Grading of Recommendations Assessment, Development, and Evaluation system (GRADE) was used to rate the level of evidence. Results: Five studies were included. Risk ratios of 1.02 (95%CI 0.89-1.15), 0.93 (95%CI 0.72-1.21), 1.07 (95%CI 0.87-1.32), 0.95 (95%CI 0.80-1.13) were observed for 3 years overall survival, 5 years failure-free survival, 5 years locoregional failure-free survival and 5 years distant metastasis failure-free survival. There were no treatment-related deaths in both groups of five studies. Hematologic and gastrointestinal toxicity were the most significant for patients during adjuvant chemotherapy. The level of evidence was low. Conclusion: Compared with concurrent chemoradiotherapy alone, concurrent chemotherapy followed by adjuvant chemotherapy did not improve prognosis. More toxicity was found during adjuvant chemotherapy.

• Journal of Acupuncture Research
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• 제34권3호
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• pp.13-21
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• 2017

Objectives : The purpose of this study was to investigate the effect of acupuncture treatment (AT) in the tendency of increase of the need for AT for the treatment of Parkinson's disease (PD) worldwide and to investigate the advancements in AT research in Korea and the future directions of research on this topic. Methods : Until May 2017, the PubMed, Scopus, Medline, and four Korean databases were searched. The searched keywords were "Parkinson's disease", "Acupuncture", and "Intervention study". The intervention groups from all screened original studies were analyzed and the methods used to determine the effect of AT on PD were examined. Results : A total of 17 studies were grouped by country on the basis of the first author's position, of which 10 studies were conducted in China, four in the United States, two in Korea, and one in Brazil. The most common type of intervention was electroacupuncture (nine studies), followed by AT (six studies), and a combination of AT and bee venom AT (two studies). The most frequently used acupoints in AT were Baihui (GV20), Taichong (LR3), Zusanli (ST36), Sanyinjiao (SP6), and Yanglingquan (GB34). The most commonly used tool for evaluation of PD was the Unified Parkinson's Disease Rating Scale III, which assesses motor functions. Conclusion : The screened studies reported that there were no adverse effects of AT on drug therapy, and AT reduced the dose of drugs used in PD treatment. Future studies on PD treatment with AT should use the acupoints GV20, LR3, ST36, SP6, and GB34, and the meridians Gallbladder meridian and Governor Vessel. Clinical studies on PD should use CONSORT or STRICTA to ensure the quality of national studies and allow the development of new tools for the assessment of the effect of AT on PD using the above criteria.

• 한국융합학회논문지
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• 제8권2호
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• pp.53-62
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• 2017

이 연구는 중국 대학생들의 한국 의료관광 융합서비스 이용에 대한 선호와 만족에 영향을 미치는 요인들을 파악하여 중국 의료관광객 유치를 위한 방안을 마련하는데 필요한 기초자료를 제공하기 위한 것이다. 이 연구를 위하여 구조화된 설문지를 개발하여 2015년 5월 1일부터 15일 사이에 중국 국제대학생 175명을 대상으로 자료를 수집하였다. 한국 의료 서비스에 대한 기대와 평가를 비교하기 위하여 t-검정을 실시하였다. 한국 의료관광 서비스 이용에 대한 만족도에 영향을 미치는 요인들을 파악하기 위하여 선형회귀모형을 추정하였다. 다양한 회귀모형을 추정하였으며, 그 중에서 간결하면서 한국 의료서비스에 대한 만족도의 변량을 비교적 잘 설명해주는 최선의 모델을 선정하였다. 회귀모형 추정 결과 기술, 의료관광서비스의 질, 의료비용은 한국 의료서비스 이용에 대한 만족도와 유의하게 연관되어 있었다. 이 연구결과에 따르면, 중국 대학생들을 대상으로 한국의 의료서비스에 대한 이해를 높일 수 있는 전략이 필요하다. 중국 의료관광객 유치 활성화를 위해서는 기술수준의 제고, 의료서비스의 질 향상, 합리적인 비용의 설정도 중요하다.

• 한국약용작물학회지
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• 제13권5호
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• pp.219-226
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• 2005

Sanguisorbae radix (SR) from Sanguisorba officinalis L. (Losaceae) is widely used in Korea and China due to its various pharmacological activity. The present study aims to investigate the effect of the methanol extract of SR on amyloid ${\beta}$ Protein(25-35) $(A{\beta}\;(25-35))$, a synthetic 25-35 amyloid peptide, -induced neurotoxicity using cultured rat cortical neurons. SR, over a concentration range of $10-50\;{\mu}g/ml$, inhibited the $A{\beta}$ (25-35) $(10\;{\mu}M)-induced$ neuronal cell death, as assessed by a 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyl-tetrazolium bromide (MTT) assay and the number of apoptotic nuclei, evidenced by Hoechst 33342 staining. Pretreatment of SR $(50\;{\mu}g/ml)$ inhibited $10\;{\mu}M\;A{\beta}$ (25-35)-induced} elevation of cytosolic calcium concentration $([Ca^{2+}]c)$, which was measured by a fluorescent dye, fluo-4 AM. SR $(10\;and\;50\;{\mu}g/ml)$ inhibited glutamate release into medium induced by $10\;{\mu}M\;A{\beta}(25-35)$, which was measured by HPLC, and generation of reactive oxygen species. These results suggest that SR prevents $A{\beta}$ (25-35)-induced neuronal cell damage in vitro.