• Korean Journal of Oriental Medicine
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• v.3 no.1
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• pp.17-40
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• 1997

${\ulcorner}$Classified Collection of Medical Prescriptions${\lrcorner}$(${\ulcorner}$醫方類聚${\lrcorner}$ is a medical book which classifies and edits the existing books. First of all, it is not until finishing the study of reference books that we can study the ${\ulcorner}$Classified Collection of Medical Prescriptions${\lrcorner}$ in earnest. We did not take traditional non-systematic methods to study the reference books of ${\ulcorner}$Classified Collection of Medical Prescriptions${\lrcorner}$ systematically. We investigated the title of 'reference book's name' as a reference book and did not investigate re-reference books. The number of reference books are one hundred forty-two volumes. Most of the reference books are medical books; some books are about Taoism and Buddhism. The title of the reference books are given a name by various methods. But these methods have a lot of problems. First, the same title book misapply an alias, the original text name and an abbreviated name. Second, a chapter name misapplies reference books. Third, reference books misapplies a chapter name. Forth, the writer and book name misapplies reference books and so on. From quotation collection about ${\ulcorner}$Classified Collection of Medical Prescriptions${\lrcorner}$'s characteristic point fellows below in three kinds. First, it emphasizes medical therapy. Second, most of Song(宋) period, Geum Yuan(金 元) period of China reference books take place in here. During this period it had accepted studying theory from clinical accumulation and the result of re-clinical studies reception based on theory research, and also had accepted Geum Yuan's expansive theory. Third, by adding technical books of a professional assortment, it has raised its profession of division.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.16 no.2
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• pp.163-187
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• 2010

The concept of latent-gi(伏氣) was first mentioned in Yellow Emperor's Canon of Internal Medicine. For example, Elementary Questions states, "Damage by cold in winter necessarily engenders warm disease in the spring." Zhang Zhong-Jing of Han Dynasty in On Cold Damage and Miscellaneous Diseases mentions warm disease, stating, for example, "Greater yang disease with heat effusion and cough and without aversion to cold is warm disease. If sweating is applied, and there is generalized heat, this is wind warmth." However, the concept of warm disease was not central to his systematic presentation of externally contracted disease which placed the emphasis on wind and cold as the major causes of these diseases. Zhang Zhong-Jing's theories centuries after in the Sung Dynasty were to become the focus of the cold damage school, whereas the concept of warm disease was to become the focus of a rival school, the warm disease school. In the Sui-Tang Period, The Origin and Indications of Disease mentions warm diseases, their causes, patterns, and major principles of treatment. Successive generations of doctors wrote about warm disease, and in the Ming Dynasty writings on the subject become more prolific. This development is attributable on the one hand to the opening up of the south of China where febrile diseases tended to be of a different nature than in the north, and on the other to pestilences arising as a result of wars. In this period, Wu You-Xing in On Warm Epidemics explained in detail the laws governing the origin, development and pattern identification of warm epidemics. Notably, he posed the etiological notion of a contagious perverse gi.

• Natural Product Sciences
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• v.9 no.4
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• pp.249-255
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• 2003

Zizypus is one of the herbs widely used in Korea and China due to CNS calming effect. The present study aims to investigate the effect of the methanol extract of Zizyphi Jujube Semen (ZJS) on kainic acid (KA)-induced neurotoxicity in cultured rat cerebellar granule neuron. ZJS, over a concentration range of 0.05 to $5\;{\mu]g/ml$, inhibited KA $(500\;{\mu}M)-induced$ neuronal cell death, which was measured by a trypan blue exclusion test and a 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide (MTT) assay. Pretreatment of ZJS $(0.5\;{\mu}g/ml)$ inhibited KA$(50\;{\mu}M)$-induced elevation of cytosolic calcium concentration $([Ca^{2+}]_c)$, which was measured by a fluorescent dye, Fura 2-AM, and generation of reactive oxygen species (ROS). ZJS $(0.5\;{\mu}g/ml)$ inhibited glutamate release into medium induced by KA $(500\;{\mu}M)$, which was measured by HPLC. These results suggest that ZJS prevents KA-induced neuronal cell damage in vitro.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.2
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• pp.137-148
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• 2000

This paper is based on the 9 goat colonies along the middle and lower Yellow River valley and 7 local goat colonies in the Northeast, Tibet and the Yangtze valley. After collecting the same data about the 22 goat colonies in China and other countries, it establishes and composes the matrix of fuzzy similarity relation describing the genetic similarities of different colonies. It also clusters 38 colonies according to their phylogenetic relationship. The establishment of the matrix and the cluster are effected in terms of the frequency of 18 loci and 43 allelomorphs in blood enzyme and other protein variations. The study proves that the middle Yellow River valley is one of the taming and disseminating centers of domestic goats in the South and East of Central Asia. Compared with other goat populations in this vast area, the native goat populations in the west of Mongolian Plateau, the Qinghai-Tibet Plateau and the middle Yellow River valley share the same origin. The colonies in the lower Yellow River valley and those in the middle valley, however, are relatively remote in their phylogenetic relationship. The native goat colonies in the southeast of Central Asia can be classified into two genetic groups: "East Asia" and "South Asia" and the colonies in Southeast Asia belong to either group.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7457-7461
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• 2015

Some thyroid cancer patients undergone insufficient tumor removal in the primary surgery in China. our aim is to evaluate the impact of dissection of the recurrent laryngeal nerve during a salvage thyroid cancer operation in these patients to prevent nerve injury. Clinical data of 49 enrolled patients who received a salvage thyroid operation were retrospectively reviewed. Primary pathology was thyroid papillary cancer. The initial procedure performed included nodulectomy (20 patients), partial thyroidectomy (19 patients) and subtotal thyroidectomy (10 patients). The effect of dissection and protection of the recurrent laryngeal nerve and the mechanism of nerve injury were studied. The cervical courses of the recurrent laryngeal nerves were successfully dissected in all cases. Nerves were adherent to or involved by scars in 22 cases. Three were ligated near the place where the nerve entered the larynx, while another three were cut near the intersection of inferior thyroid artery with the recurrent laryngeal nerve. Light hoarseness occurred to four patients without a preoperative voice change. In conclusion, accurate primary diagnosis allows for a sufficient primary operation to be performed, avoiding insufficient tumor removal that requires a secondary surgery. The most important cause of nerve damage resulted from not identifying the recurrent laryngeal nerve during first surgery, and meticulous dissection during salvage surgery was the most efficient method to avoid nerve damage.

• Journal of Digital Convergence
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• v.15 no.8
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• pp.477-487
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• 2017

This paper releases strategies for firms that wish to enter into online circulation business in China. SWOT based on a Korean manufacturing company teaches us better way to approach Chinese online market. Chinese online market is under oligopoly, where Alibaba and Jingdong account for about 80% of the total market. Game theory is used as a measure of threat and opportunity between Korean manufacturer and Chinese online market retailer. Game shows that they are easy to accept opportunity and sales uplift rather than low risk. Analysis shows that Korean companies should improve its products and brand competitiveness in the offline market before entering into the Chinese online retail market. They need to prepare a localization model.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.154-154
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• 2017

In accordance with the opening of the Korean rice market, this study was focused on establishment of database for discriminating the Korean rice varieties and imported brand rices using DNA markers. In this study, the SNP markers were developed using single nucleotide polymorphisms between the reference sequences of japonica and them of 40 brand rices which collected in Australia, China, Thailand, United States and Vietnam. The developed SNP markers were screened to a total of 360 rices including 320 Korean rice varieties and 40 imported brand rices. We selected polymorphic markers among Korean bred rive varieties and imported brand rices. The selected markers were classified into 3 grades. The markers of A grade produced DNA band in 360 rices of 30~40%, B grades produced in 40~60%, and C grades produced bands over 60% rices. First, we tried to set-up the discriminating system using the minimum SNP markers of A grade. Especially, a set of sixteen SNP markers could identify among Korean bred rice varieties and imported brand rices. Additionally, some SNP markers like NSb for Pib gene, JJ80-T for Pi5 and YL155/YL87 for Pita which linked to resistance genes to blast were used to fingerprinting system. These markers were set-up as multiplex set for enhancing the identification efficiency among rice varieties. Finally, the selected SNP markers would be used to the fluidigm assay to construct the database for elaborate discrimination of rice varieties.

• Animal Systematics, Evolution and Diversity
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• v.28 no.4
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• pp.279-290
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• 2012

Plecoglossus altivelis (ayu) is an amphidromous fish widely distributed in Northeastern Asia from the East China Sea to the northern Japanese coastal waters, encompassing the Korean Peninsula within its range. The shore lines of northeastern region in Asia have severely fluctuated following glaciations in the Quaternary. In the present study, we investigate the population genetic structure and historical demographic change of P. altivelis at a population level in East Asia. Analysis of molecular variance (AMOVA) based on 244 mitochondrial control region DNA sequences clearly showed that as the sampling scope extended to a larger geographic area, genetic differentiation began to become significant, particularly among Northeastern populations. A series of hierarchical AMOVA could detect the genetic relationship of three closely located islands between Korea and Japan that might have been tightly connected by the regional Tsushima current. Neutrality and mismatch distribution analyses revealed a strong signature of a recent population expansion of P. altivelis in East Asia, estimated at 126 to 391 thousand years ago during the late Pleistocene. Therefore it suggests that the present population of P. altivelis traces back to its approximate demographic change long before the last glacial maximum. This contrasts our a priori expectation that the most recent glacial event might have the most crucial effect on the present day demography of marine organisms through bottleneck and subsequent increase of effective population size in this region.

• Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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• v.10 no.S_4
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• pp.197-206
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• 2001

The long-range transport mechanisms of Asian dust were analyzed based on the synoptic weather system and numerical simulation by using NCEP/NCAR reanalysis and TOMS data during the periods of 1996-2001. We classified the whole weather types of eastern Asia during spring and created the representative weather types during the yellow sand events using cluster analysis and weather charts for the last 6 years(1996~2001). These long-range transport mechanisms were related to various pressure patterns including high and low, trough and ridge, and upper-level fronts. Case studies of the yellow sand events have performed by the simulation of MM5 with meteorological elements such as the horizontal wind of u and v component, potential temperature, potential vorticity, and vertical circulation during the episodic days(2~8 March 2001). In addition, the origin of the long-range transport was examined with the estimation of backward trajectory using HYSPLIT4 Model. In this paper, we concluded that three weather types at 1000 hPa, 850 hPa, 500 hPa, and 300 hPa levels were classified respectively. The dominant features were the extending continental outflow from China to Korea at 1000 hPa and 850 hPa levels, the deep trough passage and cold advection at 500 hPa and 300 hPa levels during the yellow sand events. And also, we confirmed the existence of pola $r_tropical jets in the upper-level, the behavior of potential vorticity over Korea, the estimation of potential vorticity through vertical cross section, and the transport of yellow sand through backward trajectories.es.

• Journal of Environmental Science International
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• v.25 no.1
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• pp.107-125
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• 2016

Long-term variations of $PM_{10}$ and the characteristics of local meteorology related to its concentration changes were analyzed at 4 air quality sites (Ido-dong, Yeon-dong, Donghong-dong, and Gosan) in Jeju during two different periods, such as PI (2001-2006) and PII (2007-2013), over a 13-year period. Overall, the long-term trend of $PM_{10}$ was very slightly downward during the whole study period, while the high $PM_{10}$ concentrations in PII were observed more frequently than those in PI. The concentration variations of $PM_{10}$ during the study period was clarified in correlation between $PM_{10}$ and meteorological variables, e.g. the low (high) $PM_{10}$ concentration with large (small) precipitation or high (low) radiation and in part high $PM_{10}$ concentrations (especially, Donghong-dong and Gosan) with strong wind speed and the westerly/northwesterly winds. This was likely to be caused by the transport effect (from the polluted regions of China) rather than the contribution of local emission sources. The $PM_{10}$ concentrations in "Asian dust" and "Haze" weather types were higher, whereas those in "Precipitation", "Fog", and "Thunder and Lighting" weather types were lower. The contribution of long-range transport to the observed $PM_{10}$ levels in the urban center (Ido-dong, Yeon-dong, and Donghong-dong), if estimated by comparison to the data of the background site (Gosan), was found to explain about 80% (on average) of its input.