• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.10a
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• pp.430-432
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• 2022

With the recent increase in interest in the open science movement in science and technology fields such as open access, open data, and open source, the movement to share and utilize publicly funded research products is materializing and revitalizing. In line with this trend, many efforts are being made to establish and revitalize a system for sharing and utilizing research data, which is a key resource for research in Korea. These efforts are mainly focused on collecting research data by field and institution, and linking it with DataON, a national research data platform, to search and utilize it. However, developed countries are building a system that can share and utilize not only such research data but also various types of R&D-related computing resources such as IaaS, PaaS, SaaS, and MLaaS. EOSC (European Open Science Cloud), ARDC (Australian Research Data Commons), and CSTCloud (China S&T Cloud) are representative examples. In Korea, the Korea Research Data Commons (KRDC) is designed and a core framework is being developed to facilitate the sharing of these computing resources. In this study, the necessity, concept, composition, and future plans of KRDC are introduced.

• Earthquakes and Structures
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• v.26 no.2
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• pp.97-115
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• 2024

In this paper, a database consisting of the dynamic shear modulus ratio and damping ratio test data of clay obtained from 406 groups of triaxial tests is constructed with the starting area of Xiong'an New Area as the research background. The aim is to study the nonlinear dynamic properties of clay in this area under cyclic loading. The study found that the effective confining pressure and plasticity index have certain influences on the dynamic shear modulus ratio and damping ratio of clay in this area. Through data analysis, it was found that there was a certain correlation between effective confining pressure and plasticity index and dynamic shear modulus ratio and damping ratio, with fitting degree values greater than 0.1263 for both. However, other physical indices such as the void ratio, natural density, water content and specific gravity have only a small effect on the dynamic shear modulus ratio and the damping ratio, with fitting degree values of less than 0.1 for all of them. This indicates that it is important to consider the influence of effective confining pressure and plasticity index when studying the nonlinear dynamic properties of clays in this area. Based on the above, prediction models for the dynamic shear modulus ratio and damping ratio in this area were constructed separately. The results showed that the model that considered the combined effect of effective confining pressure and plasticity index performed best. The predicted dynamic shear modulus ratio and damping ratio closely matched the actual curves, with approximately 88% of the data falling within ±1.3 times the measured dynamic shear modulus ratio and approximately 85.1% of the data falling within ±1.3 times the measured damping ratio. In contrast, the prediction models that considered only a single influence deviated from the actual values, particularly the model that considered only the plasticity index, which predicted the dynamic shear modulus ratio and the damping ratio within a small distribution range close to the average of the test values. When compared with existing prediction models, it was found that the predicted dynamic shear modulus ratio in this paper was slightly higher, which was due to the overall hardness of the clay in this area, leading to a slightly higher determination of the dynamic shear modulus ratio by the prediction model. Finally, for the dynamic shear modulus ratio and damping ratio of the engineering site in the starting area of Xiong'an New Area, we confirm that the prediction formulas established in this paper have high reliability and provide the applicable range of the prediction model.

• Journal of Microbiology
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• v.45 no.2
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• pp.105-112
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• 2007

The objective of this study was to analyze the phylogenetic composition of bacterial community in the soil of an earth-cave (Niu Cave) using a culture-independent molecular approach. 16S rRNA genes were amplified directly from soil DNA with universally conserved and Bacteria-specific rRNA gene primers and cloned. The clone library was screened by restriction fragment length polymorphism (RFLP), and representative rRNA gene sequences were determined. A total of 115 bacterial sequence types were found in 190 analyzed clones. Phylogenetic sequence analyses revealed novel 16S rRNA gene sequence types and a high diversity of putative bacterial community. Members of these bacteria included Proteobacteria (42.6%), Acidobacteria (18.6%), Planctomycetes (9.0 %), Chloroflexi (Green nonsulfur bacteria, 7.5%), Bacteroidetes (2.1%), Gemmatimonadetes (2.7%), Nitrospirae (8.0%), Actinobacteria (High G+C Gram-positive bacteria, 6.4%) and candidate divisions (including the OP3, GN08, and SBR1093, 3.2%). Thirty-five clones were affiliated with bacteria that were related to nitrogen, sulfur, iron or manganese cycles. The comparison of the present data with the data obtained previously from caves based on 16S rRNA gene analysis revealed similarities in the bacterial community components, especially in the high abundance of Proteobacteria and Acidobacteria. Furthermore, this study provided the novel evidence for presence of Gemmatimonadetes, Nitrosomonadales, Oceanospirillales, and Rubrobacterales in a karstic hypogean environment.

• Korean Journal of Plant Taxonomy
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• v.44 no.3
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• pp.191-201
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• 2014

In order to find useful taxonomic morphological characters, 17 taxa from East-Asia Astragalus and Oxytropis anertii were investigated. In this study, seed coat structure, fruit surface, and fruit anatomical structures were selected to classify the species in Astragalus. As a results, useful morphological and anatomical characters in East-Asia Astragalus were life cycle, leaflet shape, raceme, petal color, seed color, pod shape, absent or present of hairs in pod surface, bent degree of dorsal suture, and thickness of endocarp. Using medicinal sources in China, A. floridus, A. membranaceus, A. membranaceus var. mongholicus and A. tongolensis were formed same group. However, these were not completely consensus in the morphological characters. The other hand, A. koraiensis and A. sikokianus, which have controversial taxonomic issue, have clearly no differences morphological characters each other. Therefore, A. koraiensis, A. sikokianus, and A. bhotanensis should be conducted a comparative study on the DNA sequences and molecular cytology in order to clarify the taxonomic treatments in the near future.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.2
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• pp.143-151
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• 2015

This study was aimed at investigating the syndrome differentiation and herbal medicine of Thromboangiitis Obliterans by reviewing Chinese traditional medicine's journals. The journal search was carried out using China National Knowledge Infrastructure(CNKI) and PubMed from September 2009 to August 2014. Searching key words were the various combination of "Thromboangiitis Obliterans", "traditional chinese medicine", "syndrome differentiation", "herbal medicine". The final selection of 33 studies were selected and summarized by researchers. The syndrome differentiation was classified as yang deficiency, cold syncope and blood stasis. The most frequently herbs were blood-activating and stasis-resolving medicinals.

• Journal of the Korean Society of Costume
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• v.63 no.8
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• pp.125-142
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• 2013

Soek(Xi) was the highest ranked shoe that was worn with the primary formal dress in East Asian countries including ancient Korea and China. This article examined Joseon's Seok as discussed in previous studies, and it explored factors such as the wearers' status, wearing situations, its morphology, its materials, and its colors in the Great Han Empire period (1897~1910), and then extracted three morphological characteristics of the Korean Seok to examine its origin. The results of the study are as follows. For women, the Seok in the Great Han Empire period was worn with Won-sam(圓衫) and No-eui(露衣) as well as Jeok-eui(翟衣), and hence its range of wearing was extensive. Also, red Seok was worn with deep red colored Dae-sam(大衫)-styled Jeok-eui in the Joseon period(1392~1897), and blue Seok with deep blue Jeok-eui in the Great Han Empire period. This suggests the possibility that wearing of deep blue Jeok-eui occurred after 1906 in terms of the use of blue Seok. As for its morphology, its leg-less form was maintained into the late Joseon period, and there were no great changes in its name. The characteristics of the Korean Seok's morphological structure consisted of a shoe leg, the wood-less bottom and pearl ornament. As a result of the examination of the origin of those characteristics, it has been clarified that the form in which Gu, Eok, Jun(純), are attached in the structure with a shoe leg originated from the combination of Hwa(靴) and Li(履) after the two types of shoes were alternately worn in the Song (宋) period. Also, it was confirmed that the woodless bottom appeared between the periods from Wei Jin Northern and Southern Dynasties(魏晉南北朝) to Sui(隋), and the pearl ornament occurred in the Jin(金) period.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.11
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• pp.5747-5752
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• 2012

Purpose: The main objective of the present study was to evaluate the efficacy and toxicity of concurrent chemoradiotherapy followed by adjuvant chemotherapy compared with concurrent chemoradiotherapy alone in the treatment of locoregionally advanced nasopharyngeal carcinoma. Methods: The search strategy included Pubmed, Embase, the Cochrane Library, China National Knowledge Internet Web, Chinese Biomedical Database and Wanfang Database. We also searched reference lists of articles and the volumes of abstracts of scientific meetings. Randomized controlled trials (RCTs) that compared concurrent chemoradiotherapy followed by adjuvant chemotherapy with concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma were included. Meta-analysis was performed with RevMan 5.1.0. The Grading of Recommendations Assessment, Development, and Evaluation system (GRADE) was used to rate the level of evidence. Results: Five studies were included. Risk ratios of 1.02 (95%CI 0.89-1.15), 0.93 (95%CI 0.72-1.21), 1.07 (95%CI 0.87-1.32), 0.95 (95%CI 0.80-1.13) were observed for 3 years overall survival, 5 years failure-free survival, 5 years locoregional failure-free survival and 5 years distant metastasis failure-free survival. There were no treatment-related deaths in both groups of five studies. Hematologic and gastrointestinal toxicity were the most significant for patients during adjuvant chemotherapy. The level of evidence was low. Conclusion: Compared with concurrent chemoradiotherapy alone, concurrent chemotherapy followed by adjuvant chemotherapy did not improve prognosis. More toxicity was found during adjuvant chemotherapy.

• Journal of Acupuncture Research
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• v.34 no.3
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• pp.13-21
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• 2017

Objectives : The purpose of this study was to investigate the effect of acupuncture treatment (AT) in the tendency of increase of the need for AT for the treatment of Parkinson's disease (PD) worldwide and to investigate the advancements in AT research in Korea and the future directions of research on this topic. Methods : Until May 2017, the PubMed, Scopus, Medline, and four Korean databases were searched. The searched keywords were "Parkinson's disease", "Acupuncture", and "Intervention study". The intervention groups from all screened original studies were analyzed and the methods used to determine the effect of AT on PD were examined. Results : A total of 17 studies were grouped by country on the basis of the first author's position, of which 10 studies were conducted in China, four in the United States, two in Korea, and one in Brazil. The most common type of intervention was electroacupuncture (nine studies), followed by AT (six studies), and a combination of AT and bee venom AT (two studies). The most frequently used acupoints in AT were Baihui (GV20), Taichong (LR3), Zusanli (ST36), Sanyinjiao (SP6), and Yanglingquan (GB34). The most commonly used tool for evaluation of PD was the Unified Parkinson's Disease Rating Scale III, which assesses motor functions. Conclusion : The screened studies reported that there were no adverse effects of AT on drug therapy, and AT reduced the dose of drugs used in PD treatment. Future studies on PD treatment with AT should use the acupoints GV20, LR3, ST36, SP6, and GB34, and the meridians Gallbladder meridian and Governor Vessel. Clinical studies on PD should use CONSORT or STRICTA to ensure the quality of national studies and allow the development of new tools for the assessment of the effect of AT on PD using the above criteria.

• Journal of the Korea Convergence Society
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• v.8 no.2
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• pp.53-62
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• 2017

This study was to find the factors influencing satisfaction of Korean medical tour services of Chinese college students. Structured questionnaire was developed to collect data. The data were collected from the 175 students between May 1 and May 15 in 2015 in an international college in China. The expectations and the evaluations on the Korean medical tour services were compare by t-test. To find the factors influencing satisfaction on Korean medical tour services, diverse linear regression models were estimated. According to the best fit regression model, technologies, quality of medical tour services, and health care cost significantly and positively influenced satisfaction on the Korean medical tour services. The results of the study suggested that we need to prepare marketing strategies to improve understandings on Korean medical tour services for the Chinese college students. Improvement of technology, improvement of quality of health service, and setting of reasonable price are important to attract more Chinese patients to Korea.

• Korean Journal of Medicinal Crop Science
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• v.13 no.5
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• pp.219-226
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• 2005

Sanguisorbae radix (SR) from Sanguisorba officinalis L. (Losaceae) is widely used in Korea and China due to its various pharmacological activity. The present study aims to investigate the effect of the methanol extract of SR on amyloid ${\beta}$ Protein(25-35) $(A{\beta}\;(25-35))$, a synthetic 25-35 amyloid peptide, -induced neurotoxicity using cultured rat cortical neurons. SR, over a concentration range of $10-50\;{\mu}g/ml$, inhibited the $A{\beta}$ (25-35) $(10\;{\mu}M)-induced$ neuronal cell death, as assessed by a 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyl-tetrazolium bromide (MTT) assay and the number of apoptotic nuclei, evidenced by Hoechst 33342 staining. Pretreatment of SR $(50\;{\mu}g/ml)$ inhibited $10\;{\mu}M\;A{\beta}$ (25-35)-induced} elevation of cytosolic calcium concentration $([Ca^{2+}]c)$, which was measured by a fluorescent dye, fluo-4 AM. SR $(10\;and\;50\;{\mu}g/ml)$ inhibited glutamate release into medium induced by $10\;{\mu}M\;A{\beta}(25-35)$, which was measured by HPLC, and generation of reactive oxygen species. These results suggest that SR prevents $A{\beta}$ (25-35)-induced neuronal cell damage in vitro.