• Korean Journal of Hydrosciences
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• v.1
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• pp.15-25
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• 1990

Spatially varied unsteady flow in a groave-like channel of a sloping roof is analyzed by numerical solution of Saint Venant equations. Depth variations are discussed with different slopes and bed roughness of the channel. Time to equilibrium is found to be inversely proportional to the kinematic flow number. The design of roof drainage system by different schemes is included.

• Journal of Physiology & Pathology in Korean Medicine
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• v.34 no.6
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• pp.326-333
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• 2020

Nitrate-nitrite-nitric oxide (NO) pathway is a major alternative source of NO and is essential for NO - dependent physiological functions in body. Food supplements having nitrate/nitrite can improve metabolic syndromes including hypertension through antioxidant activity or vasodilation. The purpose of this study was to observe the effects of fermented garlic (F. garlic) having high concentration of NO2- on changes in blood flow and nitric oxide synthesis in the cerebral cortex of rodents. The generation of nitric oxide detected by a chemi-luminescence detector was higher in F. Garlic compared with NaNO2 solution under artificial gastric juice with pH 2.0. Ether F. garlic or NaNO2 diluted with artificial cerebrospinal fluid was directly applied into around the needle probe of laser Doppler flow meter that was located on epidural surface of the cortex. Direct application of F. garlic resulted in increase of cerebral blood flow detected by a laser Doppler flow meter with a dose-dependent manner. Compared with NaNO2 solution, F. garlic produced changes in cerebral blood flow at lower concentration of NO2-. Pretreatment of methylene blue, a guanylyl cyclase inhibitor prevented upregulation of cerebral blood flow by the treatment of F. garlic. In addition, the application of F. garlic with 250, 500ppm of NO2- caused significantly the production of NO in the cortical tissue but NaNO2 solution with 500ppm of NO2- did not. In summary, these results suggested that F. garlic with high content of NO2- induce increase in cerebral blood flow through nitric oxide-dependent signal pathway.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.13 no.3
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• pp.194-199
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• 2001

The turbulent flow resistance of water solution with polymer is reduced as compared with that of pure water. This effects is named th drag reduction and offers the significant reduction of the pumping power and the energy consumption. But the intense shear forces and the high temperature experienced by the polymer solution when passing through the pipes cause the degradation a loss of drag reduction effectiveness. Especially, the degradation behavior is found to be strongly dependent on temperature. This mechanical and thermal degradation can be avoided by adding materials such as surfactant to the polymer solution, which enhance the bonding force between molecules. In the present study, Copolymer and SDS were utilized and they were mixed in 10 different mixture ratios, while total concentration was fixed as 100wppm. Degradation of Copolymer-SDS mixture solutions was investigated experimentally in closed loop at the temperature of $10^{\circ}C\; and\; 80^{\circ}C$ with various flow average velocities of 1.5 m/sec, 3.0m/sec, and 4.5m/sec. Degradation characteristics of polymer solution without surfactant show a radical loss of drag reduction effectiveness at high temperature. Degradation alleviation ability of surfactant is especially effective at high temperature. Consequently, this results show that the addition of surfactant to the polymer solution can control unfavorable degradation phenomena for high temperature systems.

• Proceedings of the Membrane Society of Korea Conference
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• 2003.11a
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• pp.207-209
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• 2003

• Proceedings of the Korean Society for Bio-Environment Control Conference
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• 2000.10a
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• pp.73-76
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• 2000

• Toxicological Research
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• v.14 no.2
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• pp.143-149
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• 1998

This study was carried out to evaluate the testicular toxicity of 2-bromopropane (2-BP), which recently caused occupational intoxication on the reproductive and hematopoietic system in Koreans, using light microscopy, immunohistochemistry and flow cytometry. 10 weeks old male Sprague-Dawley (SD) rats were treated with 0.5 g/㎏/day of 2-BP orally for 8 consecutive weeks. The testes of the rats were vascularly perfused with Karnovsky's solution or immersed in Bouin's solution, embedded in plastic and evaluated with light microscopy. And relative proportions of haploid, diploid, and tetra-ploid states of DNA ploidy in the testicular cell suspensions of the SD rats were examined by flow cytometry. 2-BP induced severe testicular atrophy, depletion and degeneration of spermatogonia, spermatocytes, and spermatids and mild hyperplasia of Leydig cells without significant morphological changes. The Leydig cell hyperplasia was confirmed by immunohistochemistry using proliferating cell nuclear antigen (PCNA). The immunopositive cells against PCNA were observed in the nuclei oj some interstitial cells. Relative proportions of haploid states of DNA ploidy decreased in the atrophic testicular cell suspensions comparing with those of the control. In conclusion, 2-BP induced testicular atrophy with Leydig cell hyperplasia as examined by histopathology, immunohistochemistry and DNA flow cytometry.

• Korean Journal of Computational Design and Engineering
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• v.1 no.1
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• pp.56-64
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• 1996

A quadrilateral-triangular mixed grid method for the solution of incompressible viscous flow is presented. The solution domain near the body surface is meshed using elliptic grid geneator to acculately simulate the viscous flow. On the other hand, we used unstructured triangular grid system generated by advancing front technique of a simple automatic grid generation algorithm in the rest of the computational domain. The present method thus is capable of not only handling complex geometries but providing accurate solutions near body surface. The numerical technique adopted here is PISO type finite element method which was developed by the present author. Investigations have been made of two-dimensional unsteady flow of Re=550 past a circular cylinder. In the case of use of the unstructured grid only, there exists a considerable amount of difference with the existing results in drag coefficient and vorticity at the cylinder surface; this may be because of the lack of the grid clustering to the surface that is a inevitable requirement to resolve the viscous flow. However, numerical results on the mixed grid show good agreements with the earlier computations and experimental data.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.8 no.2
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• pp.267-278
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• 1996

Steady, laminar, forced convection flow and heat transfer in the entrance region of an internally finned circular duct with a finite thermal conductivity has been analyzed numerically. The problem under investigation is a three-dimensional boundary layer problem, and is solved by employing a marching-type procedure which involves solution of a series of 2-dimensional elliptic problems in the cross-stream plane. Two types of inlet hydrodynamic conditions are considered : (a) uniform velocity flow and (b) fully developed flow. From the above inlet conditions, the effects of the fin height(h), fin number(N) and conductivity ratio($k_r$) on the flow and thermal characteristics are investigated. The numerical results show that the height and number of fins, and ratio of the solid to fluid thermal conductivity have pronounced effect on the solution. Considering pressure drop, optimized dimensionless fin height is 0.4.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.9 no.4
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• pp.103-112
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• 1989

A numerical model for Steady state groundwater flow has been established to understand the groundwater flow phenomena near a radioactive waste repository. The integrated finite difference method based on a network composed of nodes and members was applied to investigate groundwater flow in homogeneous, heterogeneous and layered media. Its numerical solution was in good agreement with analytic solution. Physical phenomena associated in the groundwater flow depending on both hydraulic characteristics and effects of fractured zone were also investigated. A method by which feasible groundwater flow paths can be identified was developed. This method used the composite network for the geologic media near a repository and the direction of computed groudwater velocity. Groundwater velocity and travel time were predicted for the possible pathway form a repository to a biosphere.

• Korea-Australia Rheology Journal
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• v.17 no.4
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• pp.207-215
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• 2005

We present a finite difference solution for electrokinetic flow in rectangular microchannels encompassing Navier's fluid slip phenomena. The externally applied body force originated from between the nonlinear Poisson-Boltzmann field around the channel wall and the flow-induced electric field is employed in the equation of motion. The basic principle of net current conservation is applied in the ion transport. The effects of the slip length and the long-range repulsion upon the velocity profile are examined in conjunction with the friction factor. It is evident that the fluid slip counteracts the effect by the electric double layer and induces a larger flow rate. Particle streak imaging by fluorescent microscope and the data processing method developed ourselves are applied to straight channel designed to allow for flow visualization of dilute latex colloids underlying the condition of simple fluid. The reliability of the velocity profile determined by the flow imaging is justified by comparing with the finite difference solution. We recognized the behavior of fluid slip in velocity profiles at the hydrophobic surface of polydimethylsiloxane wall, from which the slip length was evaluated for different conditions.