• Environmental Mutagens and Carcinogens
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• v.25 no.2
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• pp.60-65
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• 2005

The human solute carrier, SLC41Al, is a $Mg^{2}+$ transporter that is regulated by extracellular magnesium. Although intracellular magnesium plays a fundamental role in cellular metabolism, little is known about how $Mg^{2}+$ is taken up and controlled by cells. Magnesium plays a fundamental role in cellular metabolism so that its control within the body is critical. Magnesium homeostasis is principally a balance between intestinal absorption of dietary magnesium and renal excretion of urinary magnesium. The kidney, mainly the distal convoluted tubule, controls magnesium reabsorption. Although renal reabsorption is under the influence of many hormones, selective regulation of magnesium transport is due to intrinsic control involving transcriptional processes and synthesis of transport proteins. Using microarray analysis, identification of the genetic elements involved with this transcriptional control has been begun. SLC41A1(GenBank Accession No. AJ514402), comprises 10 putative transmembrane domains, two of which are highly homologous to the integral membrane part of the prokaryote transports $Mg^{2}+$ and other divalent cations $Sr^2+,\;Zn^2+,\;Cu^2+,\;Fe^2+,\;Co^2+,\;Ba^2+,\;and\;Cd^2+,\;but\;not\;Ca^2+,\;Mn^2+,\;and\;Ni^2+.$ Transport of $Mg^{2}+$ by SLC41Al is rheogenic, voltage dependent, and not coupled to Na or Cl. Expressed SLC41Al transports a range of other divalent cations: $Mg^{2+},\;Sr^{2+},\;Zn^{2+},\;Cu^{2+},\;Fe^{2+},\;Co^{2+},\;Ba^{2+},\;and\;Cd^{2+}$. The divalent cations $Ca^{2+},\;Mn^{2+},\;and\;Ni^{2+}$and the trivalent ion $Gd^{3+}$ did not induce currents nor did they inhibit $Mg^{2+}$ transport. The nonselective cation $La^{3+}$ abolishes $Mg^{2+}$ uptake. Computer analysis of the SLC41Al protein structure reveals that it belongs to MgtE protein family & suggested that the human solute carrier, SLC41Al, might be a eukaryotic $Mg^{2+}$ transporter closely related $(60-70\%)$ protein encoded by SLC41A2 is a $Mg^{2}+$ transporter that might be involved in magnesium homeostasis in epithelial cells also transports a range of other divalent cations: $Ba^2,\;Ni^2,\;CO^2,\;Fe^2,\;or\;Mn^2,\;but\;not\;Ca^2,\;Zn^2,\;or\;Cu^{2+}$ that may have related functional properties.

• Transactions of the Korean hydrogen and new energy society
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• v.20 no.5
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• pp.447-454
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• 2009

Electrolyzed reduced water was known as an alkaline solvent than piped water, natural water and mineral water etc. By means of reduction property, electrolyzed reduced water could dissolve a solute than other kinds of water without chemicals. In this study, serpentine dissolution in electrolyzed reduced water was investigated as a novel pre-treatment of serpentine which was a minerals for carbon dioxide sequestration. The elements (Ca, Si, Mg etc.) of serpentine were dissolved rapidly at early in the dissolvation then after some minutes the solubilities of serpentine elements showed stable state without abrupt changes. In spite of serpentine elements dissolution, chemical bondings and crystallographic structure of serpentine were not changed. It was explained that the dissolution mechanism of serpentine occurred from surface in electrolyzed reduced water and bulk structure sustained without collapse.

• Journal of Korea Foundry Society
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• v.13 no.1
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• pp.71-80
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• 1993

Squeeze casting has advantages to improve mechanical properties of nonferrous castings without losing high productivity. Sound pore free structure makes it possible to be subjected to heat treatment and welding. This process became popular to produce lighter automobile parts alternating cast iron parts. It has, however, two disadvantages of segregation and scattered structure due to the solidified layers in sleeve. In this study segregation behavior of squeeze cast Al-7%Si-0.3%Mg alloy bars was investigated using HVSC machine under various injection conditions. Degree of segregation decreased with injection pressure and effect of injection velocity on it was small. Segregation mode of solute was strongly governed by solidification mode and flow pattern.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2003.05a
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• pp.127-132
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• 2003

The purpose of current study is about how to construct wall-type APT in slip form and Deck plate applied different connection of materials that wall and slab. A proposal construct's solution is using the continuous a binding string that the main of contents are slab or stairs which horizon structure part construction is joined the vertical structure part, new we Proposed of 2 solution that new technology development. We'll suggest that the development is in the construct of higher stories APT more better other construction method. We expect that the new method is good but we have many things to solute themes. Thus, we decided that this development contents are needed that correct structural investigation and constructor's security of speciality and through a fact construct, correct verification.

• Journal of the Korean Society of Food Science and Nutrition
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• v.24 no.6
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• pp.984-989
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• 1995

The concentration-efficiencyh of blue dextran solution in the progressive freeze-concentration was related to the freezing conditions such as the freezing speed and the stirring speed in the solution phase. From the theoreticla balance equation of heat and mass transfer at freezing front, the relationship between the freezing conditions and the ice structure at freezing front was drived. A high freeze-concentration efficiency was obtained under the operating conditions represented by a low speed of freezing and a high speed of stirring. The operating conditions were related to a smooth solid-liquid interface and these results were well explained by the theoretical equation. Effect of the solute component size on the concentration efficiency in the progressive freezeconcentration was also tested. The concentration efficiency of latex particles showed a lower value than that of blue dextran, however, its difference was insignificant.

• Korean Journal of Materials Research
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• v.28 no.6
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• pp.317-323
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• 2018

Crystal structure of the $L1_2$ type $(Al,X)_3Ti$ alloy (X = Cr,Cu) is analyzed by X-ray diffractometry and the nonuniform strain behavior at high temperature is investigated. The lattice constants for the $L1_2$ type $(Al,X)_3Ti$ alloys decrease in the order of the atomic number of the substituted atom X, and the hardness tends to increase. In a compressive test at around 473K for $Al_{67.5}Ti_{25}Cr_{7.5}$, $Al_{65}Ti_{25}Cr_{10}$ and $Al_{62.5}Ti_{25}Cu_{12.5}$ alloys, it is found that the stress-strain curves showed serration, and deformation rate dependence appeared. It is assumed that the generation of serration is due to dynamic strain aging caused by the diffusion of solute atoms. As a result, activation energy of 60-95 kJ/mol is obtained. This process does not require direct involvement. In order to investigate the generation of serrations in detail, compression tests are carried out under various conditions. As a result, in the strain rate range of this experiment, serration is found to occur after 470K at a certain critical strain. The critical strain increases as the strain rate increases at constant temperature, and the critical strain tends to decrease as temperature rises under constant strain rate. This tendency is common to all alloys produced. In the case of this alloy system, the serration at around 473K corresponds to the case in which the dislocation velocity is faster than the diffusion rate of interstitial solute atoms at low temperature.

• Journal of Nutrition and Health
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• v.29 no.10
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• pp.1059-1071
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• 1996

This study was performed to investigate the effect of dietary protein level on renal senescence. Male rats of 337.8$\pm$5.7g body weight were underlateral nephrectomy or shamoperation. The rats were divided into high protein(40% casein), normal protein(15% casein) and low protein(8% casein)diets and fed experimental diets ad libitum for 24 weeks. The results are summarized as follows. There was a hypertophy of the remnant kidney of uninephrectomized rats of 40% or 15% protein group, coming up to the comparable weights of both kidneys of sham-operated rats. However, the hypertrophic effect was not seen in uninephrectomized rats of 8% protein group. Serum albumin was lower in uninephrectomized rats. With increasing dietary protein level blood urea nitrogen was increased, whereas, urinary urea nitrogen excretion was decreased. Urinary solute excretion was higher in uninephrectomized group than in sham-operated group. However, effect of dietary protein level on urinary solute excretion varied dpending on th solutes tested. GFR and urinary protein excretion, throughout experiment, increased with feeding period and with dietary protein level. Proteinuria was most severe in uninephrectomized rats fed 40% casein diet. Maximum urine concentration ability measured after dehydration was not different among the experimental groups. Light microscopic examination showed focal segmental glomerulosclerosis and mild increas of glomerular mesangial matrix in uninephrectomized rats fed 40% and 15% protein diet, however, which was not observed in uninephrectomized rats fed 8% protein diet and in sham-operated rats fed 40% diet. Immunofluorescence studies revealed segmental deposits of albumin in the mesangium and capillary loops in high protein and uninephrectomized groups. Minimal granular deposition of IgG was noted in the mesangium of all experimental groups. In conclusion, high protein intake accelerated deterioration of renal function and it was correlated with morphological change. Low protein intake was effective in preventing these changes.

• Journal of the Korean Chemical Society
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• v.32 no.5
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• pp.458-463
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• 1988

The solubility parameter theory for retention behaviors of phenols in a reversed phase liquid chromatography can be applied to limited ranges of the aqueous solvent system. The many examples of the exception to this theory were found to show no agreement with the retention behavior of phenols. Therefore, a new solute-solvent interaction parameter, ${\delta}_{im}$ is added to the Schoenmakers equation of the solubility parameter theory in LC to approach the equation to the real one. The new solute-solvent interaction pararneter, ${\delta}_{im}$ depends on the kinds of solvent, the solvent composition and the structure of solutes. The parameter, ${\delta}_{im}$ has the linear relationship with the solubility parameter of mobile phase, ${\delta}_{im}$. The prediction of retention behavior by this modified equation turns out to be greater than the previous one.

• Journal of the Korean Ceramic Society
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• v.29 no.4
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• pp.265-272
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• 1992

Role of CaO in the sintering of 12Ce-TZP ceramics was studied. The addition of small amounts of CaO increase the densification rate of 12Ce-TZP by altering lattice defect structure and the diffusion coefficient of the rate controlling species, namely cerium and zirconium cations. CaO also inhibits grain growth during sintering and allows the sintering process to proceed to theoretical density by maintaining a high diffusion flux of vacancies from the pores to the grain boundaries. The inhibition of grain growth is accomplished by the segregation of solute at the grain boundaries, causing a decrease in the grain boundary mobility. The segregation of calcium was revealed by AES study.

• Journal of Powder Materials
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• v.4 no.4
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• pp.252-257
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• 1997

Cu-brazed layer between the sintered-cam(Fe-5Cr-lMo-0.5P-2.5C, wt%) and seamless steelpipe(0.25-0.35C, 0.3-1.0 Mn, bal Fe, wt%) in the camshaft shows a columnar structure of $\gamma$-phase growing from the steel pipe. Liquid phase sintered 60Fe-40Cu alloys are carburized to simulate the brazing process giving rise to the columnar growth. Liquid film migrations and columnar growth of $\gamma$-grains are observed in the carburized regions. The $\gamma$-grains grow in the same direction as the C-diffusion. Fe-solubility in the liquid of carburized region is higher than in the uncarburized by about 0.3 at%. The columnar growth is driven by the gradient of the supersaturated Fe-solute in the liquid between two adjacent $\gamma$-grains.