• Title/Summary/Keyword: Software V&V

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Association Between Green Tea and Colorectal Cancer Risk: A Meta-analysis of 13 Case-control Studies

  • Wang, Xue-Jun;Zeng, Xian-Tao;Duan, Xiao-Li;Zeng, Huan-Chao;Shen, Rui;Zhou, Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3123-3127
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    • 2012
  • Objective: Experimental studies have suggested green tea to be a chemopreventive agent for colorectal cancer, and many studies have examined possible associations. However, the conclusions were inconsistent or even contradictory, so we performed a meta-analysis based on published case-control studies to explore if green tea is indeed a protective factor. Methods: PubMed was searched up to May $10^{th}$, 2012 for relevant studies, and references of included studies were manually searched. Finally 13 eligible studies, involving 12,636 cases and 38,419 controls were identified. After data extraction, a meta-analysis was performed using CMA v2 software. Results: The results indicated there may be a weak but not statistically significant reduced risk of colorectal cancer with high dose of green tea intake (OR=0.95, 95% CI:0.81-1.11, p=0.490.69-0.98). This protective effect was also found in all subgroups, except in American and European populations. Sensitivity analysis indicated the result to be robust. Publication bias was not detected by either funnel plot or Egger tests. Conclusion: The results of this meta-analysis indicate a weak lower tendency for colorectal cancer development with green tea consumption, but available epidemiologic data are insufficient to conclude that green tea may protect against colorectal cancer in humans.

Association Between p53 Arg72Pro Polymorphism and the Risk of Human Papillomavirus-related Head and Neck Squamous Cell Carcinoma: A Meta-analysis

  • Xia, Ling-Yun;Zeng, Xian-Tao;Li, Cheng;Leng, Wei-Dong;Fan, Ming-Wen
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.6127-6130
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    • 2013
  • This study aimed to investigate the association between p53 Arg72Pro polymorphism and the risk of human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) by conducting meta-analysis. The PubMed database was searched for relevant studies until May 30, 2013. Relevant studies were selected and data were extracted by two independent authors. Overall, subgroup, and sensitivity analyses were then conducted using the Comprehensive Meta-Analysis v2.2 software. Wild-genotype ArgArg was considered as reference [odds ratio (OR) = 1.00]. Nine studies involving 1071 HNSCC cases were obtained. Meta-analysis results indicated no association between p53 Arg72Pro polymorphism and the risk of HPV-related HNSCC: for Pro/Pro vs. Arg/Arg, OR = 1.17, 95% confidence interval (CI) = 0.70-1.98; for Arg/Pro vs. Arg/Arg, OR = 1.25, 95% CI = 0.97-1.72; and for (Pro/Pro + Arg/Pro) vs. Arg/Arg, OR = 1.28, 95% CI = 0.95-1.70. These meta-analysis results were supported by subgroup and sensitivity analysis results. In conclusions, p53 Arg72Pro polymorphism is a potential marker of HP infection-related HNSCC rather than a susceptibility gene polymorphism.

MHC Class II+ (HLA-DP-like) Cells in the Cow Reproductive Tract: I. Immunolocalization and Distribution of MHC Class II+ Cells in Uterus at Different Phases of the Estrous Cycle

  • Eren, U.;Sandikci, M.;Kum, S.;Eren, V.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.1
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    • pp.35-41
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    • 2008
  • This study was undertaken to investigate the distribution of major histocompatibility complex class II positive (MHC II+) (HLA-DP-like) cells in the cow uterus (cervix, corpus and cornu uteri) and to compare these cells between the estrus and diestrus phases of the estrous cycle. Twenty-nine multiparous cows were used. Tissue samples from the middle of the cervix, the corpus and the right cornu were taken immediately after slaughter at the estrus or diestrus phase. Streptavidin-biotin peroxidase complex staining was used to detect MHC II+ cells. The number of MHC II+ cells per unit area of tissue was counted using image analysis software under a light microscope. Numerous MHC II+ cells were found in the endometrium (cervix, corpus and cornu uteri) in both estrus and diestrus. MHC II+ cells were found in the surface epithelium of the cervix uteri in diestrus, but in the corpus uteri in both estrus and diestrus and in the cornu uteri in estrus. MHC II+ cells were also found freely in the lumen of the glands and between the gland epithelia of the corpus and cornu uteri in both estrus and diestrus. There were also MHC II+ cells in the connective tissue of the myometrium and perimetrium (outside the endometrium) and around the blood vessels. Endothelial cells were frequently positive for MHC II staining. More MHC II+ cells were found in the endometrium than outside the endometrium in both estrus and diestrus (p<0.001). However, there was no difference in the numbers of positive cells between estrus and diestrus either in the endometrium or outside it. These results are the first evidence for HLA-DP-like MHC II+ cells in the bovine uterus. They indicate that antigen presentation by HLA-DP-like MHC II+ cells of the uterus is not influenced by hormonal status.

Analysis of Measurement Accuracy for Craniovertebral Junction Pathology : Most Reliable Method for Cephalometric Analysis

  • Lee, Ho Jin;Hong, Jae Taek;Kim, Il Sup;Kwon, Jae Yeol;Lee, Sang Won
    • Journal of Korean Neurosurgical Society
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    • v.54 no.4
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    • pp.275-279
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    • 2013
  • Objective : This study was designed to determine the most reliable cephalometric measurement technique in the normal population and patients with basilar invagination (BI). Methods : Twenty-two lateral radiographs of BI patients and 25 lateral cervical radiographs of the age, sex-matched normal population were selected and measured on two separate occasions by three spine surgeons using six different measurements. Statistical analysis including intraclass correlation coefficient (ICC) was carried out using the SPSS software (V. 12.0). Results : Redlund-Johnell and Modified (M)-Ranawat had a highest ICC score in both the normal and BI groups in the inter-observer study. The M-Ranawat method (0.83) had a highest ICC score in the normal group, and the Redlund-Johenll method (0.80) had a highest ICC score in the BI group in the intra-observer test. The McGregor line had a lowest ICC score and a poor ICC grade in both groups in the intra-observer study. Generally, the measurement method using the odontoid process did not produce consistent results due to inter and intra-observer differences in determining the position of the odontoid tip. Opisthion and caudal point of the occipital midline curve are somewhat ambiguous landmarks, which induce variable ICC scores. Conclusion : On the contrary to other studies, Ranawat method had a lower ICC score in the inter-observer study. C2 end-plate and C1 arch can be the most reliable anatomical landmarks.

Study on Milkability Traits in Holstein Cows

  • Lee, D.H.;Choudhary, V.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.3
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    • pp.309-314
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    • 2006
  • The present investigation was undertaken to study the milkability characteristics of Holstein cows. Out of 6,660 initial records 4,607 records were finally included in the analysis after deleting some records with an abnormal range of values for the traits considered. These 4,607 Holstein cows belonged to a total of 122 herds located in a province in Korea. The 'LactoCorder' instrument was used to electronically record the milkability traits at the milking parlor. A total of 19 traits were studied which were broadly classified into milk yield, milking speed, milking time and the electrical conductivity related traits. The SAS 9.1 statistical software was used to carry out analyses. The average maximum milk flow per minute was 3.21 kg/min, while the average milking speed during the main milking process (DMHG) had a mean value of 2.30 kg/min. The total milk yield was 14.14 kg, 62% of which was milked during the first three minutes of the milking. The average total milking time was 8.23 min. Among the three phases of the main milking process, the time of stable milk flow had the longest time (2.97 min) followed by the time at the decline phase (2.62 min). The average time taken to reach the plateau phase was 1.08 min, which can still be reduced further through improved managemental practices. Among milk yield traits, milk yield during the first two (MG2) and three (MG3) minutes of milking had high positive correlation with milking speed traits and negative correlations with almost all the milking time traits except time of incline in milk flow from 0.5 kg/min till the attainment of the plateau phase (tAN). Milking speed traits had negative correlations with total milking time, time at main milking process, time at plateau and with the time at decline. Since there was medium to high negative correlation between the milking speed and the time at plateau, there is a need for selection of cows which have intermediate milking speed so that it could require less milking time and also the optimum (higher and longer) plateau time. Proper pre-stimulation and avoiding over milking will help in further reducing the milking time and thus will add to the net profit of the farmer.

Improvement of ITSM IT Service Efficiency in Military Electronic Service

  • Woo, Hanchul;Jeong, Suk-Jae;Huh, Jun-Ho
    • Journal of Information Processing Systems
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    • v.16 no.2
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    • pp.246-260
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    • 2020
  • IT Service Management (ITSM) achieves consolidated management for the IT services supporting the acquisition system, and no outside connections can be established with such ITSM. Issues pertaining to the D2B can be addressed to System Q&A or a Call Center for problem-solving. In other words, internal staff can take the necessary measures for problems by directly connecting with ITSM. Currently, diverse innovative technologies are being used in electronics and ubiquitous computing environments. This allows us to create a better world by providing the backbone for remarkable development in our human society in the fields of electronics, devices, computer science, and engineering. Following the expansion of IT services in the military acquisition sector such as Defense Electronic Procurement, military export/import support system, etc., customers' dependence on IT for conducting business with the military or related companies is increasing, including the military's dependence on the same technology for services to the public. Nonetheless, issues pertaining to the simplified/integrated management of complex IT service management systems, including slow system recovery, lack of integrated customer service window, and insufficient information sharing, have become the priority problems that IT managers are required to solve. Therefore, this study conducted research on the integrated management of IT services provided by Korea's national defense acquisition system, which was developed based on the existing system IT Infrastructure Library (ITIL) v2, and investigated the level of satisfaction with services with focus on ensuring that it can be used for understanding the necessity of the system and its advancement in the future.

Research on the Characteristics of Skin Color of Age 25-35 Females of Korea, China, and Vietnam (한국, 중국, 베트남 25~35세 여성의 피부색 특성 연구)

  • Ahn, Cheunsoon;Kim, Su Hwan;Kim, Chanju
    • Journal of the Korean Society of Clothing and Textiles
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    • v.41 no.3
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    • pp.501-516
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    • 2017
  • Skin colors of females between the ages of 25-35 from Korea, China, and Vietnam were measured in Seoul, Beijing, and Hanoi using the Minolta CM-600d spectrophotometer. CIE Lab and Munsell HVC data of the face (forehead and both cheeks) and body (neck and arm) were analyzed using t-test, Analysis of Variance (ANOVA), Duncan's Multiple Range Test, Linear Regression Analysis, and K-Means Cluster Analysis using SPSS software. Korean females showed the highest L and V values for the face and body; Vietnamese females showed the highest b value in the face and the highest a value in the body. Higher L and b values for the face were related to higher L and b values of the body; this relationship was more prominent in Korean females. The younger age group (25-29) showed higher L values and lower b values than the older age group (30-35). Females from Korea, China, and Vietnam were grouped into Type 1 and Type 2 based on skin color. Type 1 had darker skin with more redness and yellowness and Type 2 had lighter skin with less redness and yellowness. A total of 88.2% of Korean females belonged to Type 2, 80.4% of Vietnamese females were Type 1, and Chinese females indicated an even distribution of Type 1 and Type 2.

Wooden Foreign Body in the Parotid Gland (이하선 목재 이물)

  • Moon, Yoo Jin;Choi, Hwan Jun;Kim, Mi Sun;Choi, Chang Yong;Park, Jin Gue;Kim, Jun Hyuk
    • Archives of Plastic Surgery
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    • v.35 no.2
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    • pp.201-204
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    • 2008
  • Purpose: Now the CT scanner and PACS program proved to be an excellent instrument for detection and localization of most facial foreign bodies above certain minimum levels of detectability. The severity of injury in penetrating trauma on the face is often underestimated in physical examination. Wood, with its porous consistency and organic nature, provides a good medium for microbial agents. This is a report of our recent experience with wooden foreign bodies in the parotid gland imaged with CT. Methods: A 9-year-old boy was referred for evaluation of possible retained foreign body within his face. One day earlier, he had fallen, face down approximately 1 miter onto ground. He had subsequently undergone an exploration of his right parotido-masseteric area at an outside hospital with repair of a right facial laceration. Enhanced 2 mm axial and coronal CT scans were obtained through the face. Axial and coronal CT images were obtained with a General Electric(Milwaukee, Wis) 9800 CT scanner at 130 kV, 90 mA, with a 2 mm section thickness. Results: We finally decided the linear "gas" attenuation was a foreign body because of its linear configuration, which did not conform to that of an anatomic structure, and on the basis of articles that described a wood foreign body in the orbit as having the appearance of air. We found that wood was hypoattenuating($-464{\pm}27HU$). Conclusion: We recommend this type of software program for CT scanning for any patient with an injury on the face in which a foreign body is suspected.

Dynamics of Facial Subcutaneous Blood Flow Recovery in Post-stress Period

  • Sohn, Jin-Hun;Estate M. Sokhadze;Lee, Kyung-Hwa;Lee, Jong-Mi;Park, Mi-Kyung;Park, Ji-Yeon
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 2000.11a
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    • pp.62-68
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    • 2000
  • The aim of the study was to compare effects of music and white noise on the recovery of facial blood flow parameters after stressful visual stimulation. Twenty-nine subjects participated in the experiment. Three visual stimulation sessions with aversive slides (the IAPS, disgust category) were followed by subjectively "pleasant" (in the first session), "sad" music (in the second ), and white noise (in the third ). Order of sessions was counterbalanced. Blood flow parameters (peak blood flow, blood flow velocity, blood volume) were recorded by Laser Doppler single-crystal system (LASERFLO BPM 403A) interfaced through BIOPAC 100WS with AcqKnowledge software (v.3.5) and analyzed in off-line mode. Aversive visual stimulation itself decreased blood flow and velocity in all 3 sessions. Both "pleasant" and "sad" music led to the restoration of baseline levels in all blood flow parameters, while noise did not enhance recovery process. Music on post-stress recovery had significant change in peak blood flow and blood flow velocity, but not in blood volume measures. Pleasant music had bigger effects on post-stress recovery in peak blood flow and flow velocity than white noise. It reveals that music exerted positive modulatory effects on facial vascular activity measures during recovery from negative emotional state elicited by stressful slides. Results partially support the undoing hypothesis of Levenson (1994), which states that positive emotions may facilitate process of recovery from negative emotions.

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Electron Trapping and Transport in Poly(tetraphenyl)silole Siloxane of Quantum Well Structure

  • Choi, Jin-Kyu;Jang, Seung-Hyun;Kim, Ki-Jeong;Sohn, Hong-Lae;Jeong, Hyun-Dam
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.158-158
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    • 2012
  • A new kind of organic-inorganic hybrid polymer, poly(tetraphenyl)silole siloxane (PSS), was invented and synthesized for realization of its unique charge trap properties. The organic portions consisting of (tetraphenyl)silole rings are responsible for electron trapping owing to their low-lying LUMO, while the Si-O-Si inorganic linkages of high HOMO-LUMO gap provide the intrachain energy barrier for controlling electron transport. Such an alternation of the organic and inorganic moieties in a polymer may give an interesting quantum well electronic structure in a molecule. The PSS thin film was fabricated by spin-coating of the PSS solution in THF organic solvent onto Si-wafer substrates and curing. The electron trapping of the PSS thin films was confirmed by the capacitance-voltage (C-V) measurements performed within the metal-insulator-semiconductor (MIS) device structure. And the quantum well electronic structure of the PSS thin film, which was thought to be the origin of the electron trapping, was investigated by a combination of theoretical and experimental methods: density functional theory (DFT) calculations in Gaussian03 package and spectroscopic techniques such as near edge X-ray absorption fine structure spectroscopy (NEXAFS) and photoemission spectroscopy (PES). The electron trapping properties of the PSS thin film of quantum well structure are closely related to intra- and inter-polymer chain electron transports. Among them, the intra-chain electron transport was theoretically studied using the Atomistix Toolkit (ATK) software based on the non-equilibrium Green's function (NEGF) method in conjunction with the DFT.

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