• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2519-2525
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• 2016

There are several existing reports of microarray chip use for assessment of altered gene expression in different diseases. In fact, there have been over 1.5 million assays of this kind performed over the last twenty years, which have influenced clinical and translational research studies. The most commonly used DNA microarray platforms are Affymetrix GeneChip and Quality Control Software along with their GeneChip Probe Arrays. These chips are created using several quality controls to confirm the success of each assay, but their actual impact on gene expression profiles had not been previously analyzed until the appearance of several bioinformatics tools for this purpose. We here performed a data mining analysis, in this case specifically focused on ovarian cancer, as well as healthy ovarian tissue and ovarian cell lines, in order to confirm quality control results and associated variation in gene expression profiles. The microarray data used in our research were downloaded from ArrayExpress and Gene Expression Omnibus (GEO) and analyzed with Expression Console Software using RMA, MAS5 and Plier algorithms. The gene expression profiles were obtained using Partek Genomics Suite v6.6 and data were visualized using principal component analysis, heat map, and Venn diagrams. Microarray quality control analysis showed that roughly 40% of the microarray files were false negative, demonstrating over- and under-estimation of expressed genes. Additionally, we confirmed the results performing second analysis using independent samples. About 70% of the significant expressed genes were correlated in both analyses. These results demonstrate the importance of appropriate microarray processing to obtain a reliable gene expression profile.

• The Transactions of the Korea Information Processing Society
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• v.7 no.9
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• pp.2857-2866
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• 2000

As software technology has made progress, object-oriented CASE tools have become more important. This paper presents the process and similarity in design and implementation of OODesigner, an object-oriented CASE tool, on three platfonns and outlines a kind of generic architecture for the design and the implementation of CASE tools. OODesigner is a tool that was initially developed to support OMT. An initial Unix version has been developed since 1994. In 1997, after the completion of the Unix version, we began developing a Java version and a Windows version supporting UML. The development of a CASE tool is a typical application of the Model-View-ControllerO'vIVC) paradigm. Thus, we obtained a common design pattern among the versions in the MVC point of views. This design similarity can be used to develop several kinds of CASE tools with the corresponding design notations.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2004.11a
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• pp.271-276
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• 2004

디지털방송이 시작되면서 고품질의 A/V(비디오/오디오)프로그램과 다양한 멀티미디어 컨텐츠를 제공하는 데이터방송을 처리하기 위한 수신 장치의 비중이 커지고 있다 이와 관련하여 데이터방송 환경에서 새로운 기술과 서비스가 등장할 때마다 이를 수용할 수 있는 소프트웨어를 탑재한 새로운 수신 장치가 필요하다. 일반적으로 한번 가정 내에 보급된 디지털 수신 장치의 소프트웨어 업그레이드가 용이하지 않기 때문에, 방송을 통해 이를 실현한다. 본 논문은 TV 셋탑박스 (STB) 내에 상주하는 middleware native application software 를 방송으로 다운받아 수정하는 기능을 지닌 STB 의 구현에 대해서 기술한다. 소프트웨어 업데이트 시스템은 소프트웨어를 포함하는 데이터 카루셀 스트림을 다운받아 파싱하는 다운로더, 추출된 소프트웨어를 설치하는 업데이트 로더, 그리고 예치상황이 발생하면 셋탑박스가 새로 부팅될 때, 로그 파일을 이용하여 소프트웨어를 옛날 상태의 회복시켜주는 리커버러 (recoverer)로 구성되어 있다. 다운로더는 지상파 디지털 방송 규격인 ATSC 규약에 맞게 구현하고, ATSC용 STB환경에서 테스트하고 있다.

• Journal of Broadcast Engineering
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• v.19 no.1
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• pp.14-23
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• 2014

This paper proposed controlling methods for SDN(Software Defined Network) based multiple radio access technology as the solutions of following two issues which were mainly occurred by explosive increasing of video traffic. The first one is a requirement for traffic off-loading caused by 3rd-party video service providers from the mobile network operator's viewpoint. The other one is a provision of high-speed video contents transmission services with low price. Furthermore, the performance evaluation was also conducted on the real test-bed which is composed of OpenStack cloud and SDN technology such as OpenFlow and Open vSwitch. A virtual machine running on the OpenStack provide a video service and the terminal which is able to use multiple radio access technology supports two 2.4GHz WLANs(Wireless Local Area Network) and three 5GHz WLANs, concurrently. Finally, we can get 820Mbps of the maximum transmission speed by using that five WLAN links for the single service at the same time.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.4
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• pp.1904-1926
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• 2016

Iris recognition for biometric personnel identification has gained much interest owing to the increasing concern with security today. The image quality plays a major role in the performance of iris recognition systems. When capturing an iris image under uncontrolled conditions and dealing with non-cooperative people, the chance of getting non-ideal images is very high owing to poor focus, off-angle, noise, motion blur, occlusion of eyelashes and eyelids, and wearing glasses. In order to improve the accuracy of iris recognition while dealing with non-ideal iris images, we propose a novel algorithm that improves the quality of degraded iris images. First, the iris image is localized properly to obtain accurate iris boundary detection, and then the iris image is normalized to obtain a fixed size. Second, the valid region (iris region) is extracted from the segmented iris image to obtain only the iris region. Third, to get a well-distributed texture image, bilinear interpolation is used on the segmented valid iris gray image. Using contrast-limited adaptive histogram equalization (CLAHE) enhances the low contrast of the resulting interpolated image. The results of CLAHE are further improved by stretching the maximum and minimum values to 0-255 by using histogram-stretching technique. The gray texture information is extracted by 1D Gabor filters while the Hamming distance technique is chosen as a metric for recognition. The NICE-II training dataset taken from UBRIS.v2 was used for the experiment. Results of the proposed method outperformed other methods in terms of equal error rate (EER).

• The KIPS Transactions:PartD
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• v.14D no.7
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• pp.773-782
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• 2007

Software produce line engineering is a method that prepares for future reuse and supports seamless reuse in the application development process. Analyzing the commonality and variability between products in a product line is one of the essential concerns that must be considered when building a product line. In this paper, we suggest to combine a product line engineering approach with RFID applications technology. More concretely, common activities are identified among the RFID-enable applications and the variability in the common activities is analyzed in detail. Then, we suggest reusable product line architecture as a product line asset. In addition, as a tool for supporting this research, a framework which provides both reusable product line architecture for REID applications and the components that implement concrete realization of the architecture is developed. Sharing a common architecture and reusing assets to deploy recurrent services may be considered an advantage in terms of economic significance and overall quality.

• Nuclear Engineering and Technology
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• v.50 no.6
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• pp.957-962
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• 2018

The gamma radiation shielding capability (GRSC) of two clay-materials (Ball clay and Kaolin)of Southwestern Nigeria ($7.49^{\circ}N$, $4.55^{\circ}E$) have been investigated by determine theoretically and experimentally the mass attenuation coefficient, ${\mu}/{\rho}(cm^2g^{-1})$ of the clay materials at photon energies of 609.31, 1120.29, 1173.20, 1238.11, 1332.50 and 1764.49 keV emitted from $^{214}Bi$ ore and $^{60}Co$ point source. The mass attenuation coefficients were theoretically evaluated using the elemental compositions of the clay-materials obtained by Particle-Induced X-ray Emission (PIXE) elemental analysis technique as input data for WinXCom software. While gamma ray transmission experiment using Hyper Pure Germanium (HPGe) spectrometer detector to experimentally determine the mass attenuation coefficients, ${\mu}/{\rho}(cm^2g^{-1})$ of the samples. The experimental results are in good agreement with the theoretical calculations of WinXCom software. Linear attenuation coefficient (${\mu}$), half value layer (HVL) and mean free path (MFP) were also evaluated using the obtained ${\mu}/{\rho}$ values for the investigated samples. The GRSC of the selected clay-materials have been compared with other studied shielding materials. The cognizance of various factors such as availability, thermo-chemical stability and water retaining ability by the clay-samples can be analyzed for efficacy of the material for their GRSC.

• The Journal of Advanced Prosthodontics
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• v.11 no.2
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• pp.120-127
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• 2019

PURPOSE. To determine wear amount of single molar crowns, made from four different restoratives, and opposing natural teeth through computerized fabrication techniques using 3D image alignment. MATERIALS AND METHODS. A total of 24 single crowns (N = 24 patients, age range: 18 - 50) were made from lithium disilicate (IPS E-max CAD), lithium silicate and zirconia based (Vita Suprinity CAD), resin matrix ceramic material (Cerasmart, GC), and dual matrix (Vita Enamic CAD) blocks. After digital impressions (Cerec 3D Bluecam, DentsplySirona), the crowns were designed and manufactured (Cerec 3, DentsplySirona). A dualcuring resin cement was used for cementation (Variolink Esthetic DC, Ivoclar). Then, measurement and recording of crowns and the opposing enamel surfaces with the intraoral scanner were made as well as at the third and sixth month follow-ups. All measurements were superimposed with a software (David-Laserscanner, V3.10.4). Volume loss due to wear was calculated from baseline to follow-up periods with Siemens Unigraphics NX 10 software. Statistical analysis was accomplished by Repeated Measures for ANOVA (SPSS 21) at = .05 significance level. RESULTS. After 6 months, insignificant differences of the glass matrix and resin matrix materials for restoration/enamel wear were observed (P>.05). While there were no significant differences between the glass matrix groups (P>.05), significant differences between the resin matrix group materials (P<.05) were obtained. Although Cerasmart and Enamic were both resin matrix based, they exhibited different wear characteristics. CONCLUSION. Glass matrix materials showed less wear both on their own and opposing enamel surfaces than resin matrix ceramic materials.

• Nuclear Engineering and Technology
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• v.54 no.9
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• pp.3440-3447
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• 2022

The accuracy of the photoatomic cross-section data is of great importance in the field of radiation protection, particularly in the characterization of radiation shielding materials. With the release of the latest and probably the most accurate photoatomic data library, EPDL2017, the need to re-evaluate all the existing and already established mass attenuation coefficients (MACs) of all radiation shielding materials arises. The MACs of several polymers, alloy-based, glasses, and building materials used in a nuclear medicine facility were investigated using the EPDL2017 library embedded in EpiXS software and were compared to MACs available in the literature. The relative differences between MAC_EpiXS and MACXCOM were negligible, ranging from 0.02% to 0.36% for most materials. However, for material like a glass comprising of elements Te and La evaluated near their corresponding K-edge energies, the relative differences in MACs increased up to 1.46%. On the other hand, a comparison with MACs calculated based on EPDL97 (a predecessor of EPDL2017) revealed as much as a 6.61% difference. Also, it would seem that the changes in MACs were more evident in the materials composed of high atomic number elements evaluated at x-ray energies compared to materials composed of low atomic number elements evaluated at gamma-ray energies.

• Animal Bioscience
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• v.37 no.8
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• pp.1355-1366
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• 2024

Objective: The analysis of runs of homozygosity (ROH) has been applied to assess the level of inbreeding and identify selection signatures in various livestock species. The objectives of this study were to characterize the ROH pattern, estimate the rate of inbreeding, and identify signatures of selection in the red-brown Korean native chickens. Methods: The Illumina 60K single nucleotide polymorphism chip data of 651 chickens was used in the analysis. Runs of homozygosity were analysed using the PLINK v1.9 software. Inbreeding coefficients were estimated using the GCTA software and their correlations were examined. Genomic regions with high levels of ROH were explored to identify selection signatures. Results: A total of 32,176 ROH segments were detected in this study. The majority of the ROH segments were shorter than 4 Mb. The average ROH inbreeding coefficients (F_ROH) varied with the length of ROH segments. The means of inbreeding coefficients calculated from different methods were also variable. The correlations between different inbreeding coefficients were positive and highly variable (r = 0.18-1). Five ROH islands harbouring important quantitative trait loci were identified. Conclusion: This study assessed the level of inbreeding and patterns of homozygosity in Red-brown native Korean chickens. The results of this study suggest that the level of recent inbreeding is low which indicates substantial progress in the conservation of red-brown Korean native chickens. Additionally, Candidate genomic regions associated with important production traits were detected in homozygous regions.