• Journal of The Association for Neo Medicine
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• v.1 no.2
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• pp.15-30
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• 1996

In the study about the logical basis and interpreting methods of animal experiments using rats in traditional medicine, several conclusions are obtained and summarized as following. 1. The logical basis of the animal experiments in traditional medicine is the essential homogeneity between human and rat defined as various transformation of one Qi(一氣) packed the cosmos. 2. Morphologically, the rat has abundant Yin(陰) and less Yang(陽) in most of anatomical characteristics. 3. Physiologically, the rat has unstable heart and mild temper with good fertility, which shows the features of Yin animal. 4. Pathologically, the rat shows the pathology of injury of viscera by stresses(氣激傷臟) and pathological transformations of internal water(痰飮水濕) mainly. 5. Constitutionally, the rat is alike to water type man(水形人) or Soeumin(小陰人) out of Yin Ren(陰人). 6. So, the rat is the proper experimental animal for diseases of sputum and water, emotional stimulations, endocrine system, heart, kidney, Yin syndrome(陰證) etc..

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.2
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• pp.221-227
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• 2012

In this work, we investigate the correlation between health condition and voice to study the validity and value of voice diagnosis. For this purpose, we collected voices, Health index questionnaires (Short form 36, Psychological Well Being Index) and Sasang Constitution informations on 197 males at the age of twenties. Pitch, jitter, shimmer variables were analyzed by ANOVA and Pearson correlation coefficient. There were no significant correlations between pitch, jitter, shimmer and health questionnaire score in total group regardless of Sasang Constitution. However, We found tendency of correlation between shimmer variables and health questionnaire scores in Taeeumin and Soyangin. In Soeumin and Soyangin, zitter and pitch variables were found to be slightly correlated with health questionnaire scores. Our study suggests the possibility that voice might be related with both health condition and Sasang Constitution. Our finding may motivate research activities towards diverse clinical applications of voice diagnosis and studies of voice characteristics in the Sasang constitution.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.6
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• pp.1600-1605
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• 2008

The objectives of this study were to survey the adverse reactions by Taeeumjowi-tang and to compare the tendency of symptoms by Sasang constitutional type. The clinical data for this study were based on the medical records of 78 cases collected from an oriental clinic. The major results of this survey are following: The 5.8% of Taeeum-in who took Taeeumjowi-tang showed side effects. And the 52.4% of Soeum-in and 41.6% of Soyang-in also showed side effects against Taeeumjowi-tang. They complained of excitation, irritability, restlessness, hypersensitivity, tinnitus, insomnia, upper abdominal discomfort, poor appetite, thirst, perspiration, dizziness, chest pain, tremor and evacuation troubles in common. And these adverse symptoms were similar to that by Ma-hwang. Therefore if we make a suitable medication guide for Ma-hwang based on Sasang constitutional type, it will be able to maximize the efficacy and minimize the adverse effect.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.1
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• pp.15-18
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• 2005

The methodology of constitution diagnosis is main concern in sasang constitutional medicine, but highly reliable method is not yet established. So we statistically analyzed the relationship between the constitution and characteristic factors of skin such as thickness, stiffness, roughness, and touch-feeling, using 1079 clinical data registered to SCIB(Sasang constitution Information Bank), and the following results are obtained: The skin of Taeeumin are more thick or more stiff or more rough than other constitutions. The skin of Soeumin are more soft or more feeble or more feeble-refined than other constitutions. The skin of Soyangin are more slippery or more thin or more slippery-refined than other constitutions. The differences written above were proved to be meaningful enough by Chi-square test.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.964-969
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• 2012

This study aimed to evaluate the relationship between the results of blood test and Sasang constitution. We performed blood test of 2,387 university students in Health examination. Sasang constitution was diagnosed by using the Questionnaire of Sasang Constitution Class II(QSCC II). All the data were analysed statistically by descriptive statistics, ANOVA and logistic regression analysis. The Taeeumin group showed significantly higher AST, ALT, GGT, LDH, CPK, creatinine, uric acid, total cholesterol, TG, and LDL levels than other groups, while having a lower HDL level. According to logistic regression analysis, Hb, RBC, uric acid, creatinine were effective common factors for classifying each constitution groups. In the results of this study, there were significant differences in the results of blood test between the three constitutions. But the blood test was insufficient as an objective indicator for discriminating Sasang constitutions.

• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.1
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• pp.70-74
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• 2018

The purpose of this study was to evaluate the possibility of applying Korea Sasang Constitutional Diagnostic Questionnaire(KS-15) for the Japanese. We analyzed the results of 50 Japanese participants who visited the local university hospital from October 2010 to July 2011 and their Sasang constitutions were diagnosed by a Sasang Constitutional specialist. Two items(14.3%) of total 14 items, except for BMI showed 0.4 or below in Kappa, 8 items(57.1%) were ranged from 0.4 to 0.6 and 4 items(28.6%) marked 0.6 or over. The concordance rate between the results of KS-15 and those of expert was 60% in total Japanese participants.(61.9% in Taeeumin, 60% in Soeumin, and 57.9% in Soyangin). The KS-15 could be suitable for supporting experts to diagnose the Sasang constitution of the Japanese. In order to increase usefulness, when subsequently applying KS-15 to foreign site, KS-15 should be properly adjusted in sociocultural characteristic.

• Journal of Sasang Constitutional Medicine
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• v.17 no.1
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• pp.25-32
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• 2005

1. Objectives There are two kind of ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$ and ${\ulcorner}$ShinchukBon${\lrcorner}$ These books are similar each other, and there are difference from the contents of books. Among them we studied the sentence of Gyemagakban-tang between ${\ulcorner}$GaboBon${\lrcorner}$ and ${\ulcorner}$ShinchukBon${\lrcorner}$ of ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$2. Methods The study is to compare to ${\ulcorner}$GaboBon${\lrcorner}$ and ${\ulcorner}$ShinchukBon${\lrcorner}$ on the basis of texts of ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$. 3. Results 1) We can see that Lee Je-Ma was trying to cure Soeumin by the treatment of ascent and grow up Yang(陽) and Ki(氣) as seen in the text of Gyemagakban-tang. 2) We can see that Lee Je-Ma considers sweating as the symptom of Taeumin and evacuating of stools as the symptom fo Soyangin in the text of ${\ulcorner}$GaboBon${\lrcorner}$ 3) We can see fever in the text of Gyemagakban-tang is the fundamental of the pathology of Soyangin. 4. Conclusions In addition more bliolographic study, clinical investigation will be needed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.1
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• pp.262-267
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• 2006

We verified the reproducibility of constitution by IGM and the agreement rate between sasang constitution by QSCCII and constitution by IGM. We analyzed the results of 64 subject who were judged as identical sasang constitution by repeated QSCC II. First, we compared the two results of constitutions by IGM hat peformed by one O.M.D(Oriental Medicine Doctor) at an interval of one year. Second, we examined hypothesis established by one O.M.D, that is about relation of constitutions by IGM and QSCCII, such as I type-Taeeumin, II type-Soyangin and III type-Soeumin in constitutions. There were no statistical significances in reproducibility of constitution by IGM. Although there was a tendency of relevance of sasang constitution by QSCC II with constitution by IGM, there was no statistical significance. Hypothesis that is established by clinical experiences must be verified by an effective statistical method. And there is a necessity to complement the method including mechanical measurements about constitution classification which are performed by a diagnosis relying on individual intuition.

• The Journal of Internal Korean Medicine
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• v.34 no.3
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• pp.329-337
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• 2013

This is a case report of a tracheostomized 80-year-old man suffering from sputum after stroke. His symptoms were watery sputum production requiring frequent sputum suction. The subject was diagnosed as having a deficiency of spleen qi and was treated with Gami-ijung-tang, Yukgunja-tang, Soeumin Bojungikgi-tang, and Ijin-tang extract in the herbal prescription known to dispell Dam-eum (phlegm-retained fluid). Frequency of ssputum suction and condition of sputum were checked everyday. Gamiijung-tang, Soeumin Bojungikgi-tang with Ijin-tang extract led to improvement by reducing sputum secretion. There were limitations on frequency of suction and condition of sputum which were thought to be derived from tracheostomy, however. Consequently, pathology and treatment of sputum will be different whether tracheostomy was performed or not.

• Journal of Sasang Constitutional Medicine
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• v.14 no.2
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• pp.90-97
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• 2002

Sasang Constitutional Medicine is based on the diversity of human being and medically developed the variation of response to diseases and medicines. The diversity is categorized as four groups Taeyangin, Taeumin, Soyangin, Soeumin according to morphology, physiology, pathology, and pharmacology. The phenotypes of Sasang constitutions represent that constitutions may be possessed of the different genetic backgrounds. To clarify the genetic difference among the Sasang constitutions, we performed a genetic analysis with the 3'-UTR polymorphism of ADPRT (rs=8679) as a pooled DNA sequencing method. ADPRT modulates various nuclear proteins by poly(ADP-ribosy)lation and is involved in the regulation of various cellular processes such as differentiation, proliferation, and tumor transformation. This gene is also involved in the recovery of cell from DNA damage and the brain infarction. The allele frequencies of [T/C] polymorphism of ADPRT of Soeumin and Soyangin groups were (T: 0.94/C: 0.06) and that of Taeumin and Taeyangin groups were (T: l.00/C: 0.00). The allele frequency was not showed the difference between constitution groups. This result represented that the [T/C] polymorphism of ADPRT 3' UTR region was not suitable to classify the constitutions. However, this study is the first trial of Sasang classification according to genetic polymorphism and further analysis will be necessarily to classify the genetic difference of Sasang constitution.