• Title/Summary/Keyword: Social presence

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Promoter Polymorphisms of ST3GAL4 and ST6GAL1 Genes and Associations with Risk of Premalignant and Malignant Lesions of the Cervix

  • de los Angeles Rivera-Juarez, Maria;Rosas-Murrieta, Nora Hilda;Mendieta-Carmona, Victoriano;Hernandez-Pacheco, Raquel Esneidy;Zamora-Ginez, Irma;Rodea-Avila, Carlos;Apresa-Garcia, Teresa;Garay-Villar, Onix;Aguilar-Lemarroy, Adriana;Jave-Suarez, Luis Felipe;Diaz-Orea, Maria Alicia;Milflores-Flores, Lorena;Reyes-Salinas, Juan Salvador;Ceja-Utrera, Francisco Javier;Vazquez-Zamora, Victor Javier;Vargas-Maldonado, Tomas;Reyes-Carmona, Sandra;Sosa-Jurado, Francisca;Santos-Lopez, Gerardo;Reyes-Leyva, Julio;Vallejo-Ruiz, Veronica
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.3
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    • pp.1181-1186
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    • 2014
  • Sialyltransferase gene expression is altered in several cancers, including examples in the cervix. Transcriptional regulation of the responsible genes depends on different promoters. We aimed to determine the association of single-nucleotide polymorphisms in the B3 promoter of the ST3GAL4 gene and the P1 promoter of the ST6GAL1 gene with cervical premalignant lesions or cervical cancer. A blood sample and/or cervical scrapes were obtained from 104 women with normal cytology, 154 with premalignant lesions and 100 with cervical cancer. We also included 119 blood samples of random donors. The polymorphisms were identified by sequencing from PCR products. For the B3 promoter, a fragment of 506 bp (from nucleotide -408 to +98) was analyzed, and for the P1 promoter a 490 bp (-326 to +164) fragment. The polymorphism analysis showed that at SNP rs10893506, genotypes CC and CT of the ST3GAL4 B3 promoter were associated with the presence of premalignant lesions (OR=2.89; 95%CI 1.72-4.85) and cervical cancer (OR=2.23; 95%CI 1.27-3.91). We detected only one allele of each polymorphism in the ST6GAL1 P1 promoter. We did not detect any genetic variability in the P1 promoter region in our study population. Our results suggest that the rs10893506 polymorphism -22C/T may increase susceptibility to premalignant and malignant lesions of the cervix.

A Study on type and characteristics of organization-related negative affect. (조직관련상황에서 구성원이 느끼는 불안 정서의 유형과 특성에 관한 연구)

  • Jong Dae Kim
    • Korean Journal of Culture and Social Issue
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    • v.21 no.4
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    • pp.617-647
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    • 2015
  • The purposes of this study was to develop a valid scale measuring organization-related anxiety and to use this scale to examine the relation of organizational anxiety to demographic variables, job satisfaction and organizational committment. A series of studies were conducted to develop a scale for organizational anxiety. Initially, the 97 items were adopted by expert ratings. A exploratory factor analysis with a sample of 435 workers yielded a preliminary version of organizational anxiety scale with 28 items. Subsequently, a confirmatory factor analysis was conducted with a sample of 566 workers, leaving 20 items. The final version of the organizational anxiety scale consisted of 4 sub-factors: perception of future uncertainty, perception of locus of control, interpersonal anxiety, and perception of alternatives. In this study, the examined demographic characteristics included sex, age, type of occupation, type of industry, occupational position, monthly income and educational level. Organizational effectiveness was composed of job satisfaction and organizational commitment. As mediators, organizational culture, life satisfaction, self efficacy, and social support were explored. The negative relationship was observed between organizational anxiety and organizational effectiveness. The results showed the significant differences in organizational anxiety by demographic characteristics. The mediators were explored for the relationship between organizational anxiety and job satisfaction and between organizational anxiety and organizational commitment. The negative relationship between organizational anxiety and job satisfaction was mediated by the group culture, the developmental culture, the rational culture, life satisfaction, self-efficacy, and social support. Individuals with the higher level of these mediators reported greater job satisfaction even if they experienced organizational anxiety. The partial mediation effect of the group culture, the developmental culture, the rational culture, life satisfaction, and social support was observed on the negative relationship between organizational anxiety and organizational commitment. These results implies that job satisfaction and organizational commitment can be improved with the interventions on organizational cultures, self-efficacy, and social support despite the presence of organizational anxiety. Based on these results, the implication and limitations of this study and the directions for future research discussed.

The Presence of Related Personnel Effects on the IPO of Special Listed Firms on KOSDAQ Market: Based on the Signal Effect of Third-party Social Recognition (관계인사 영입이 코스닥 기술특례기업 IPO성과에 미치는 영향: 제3자 사회적 인정의 신호 효과를 바탕으로)

  • Kiyong, Kim;Young-Hee, Ko
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.17 no.6
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    • pp.13-24
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    • 2022
  • The purpose of this study is to examine whether the existence of related personnel in KOSDAQ technology special listed firms has a signal effect on the market and affects performance when listed. The KOSDAQ technology special listing system is a system introduced to enable future growth by securing financing through corporate public offering based on the technology and marketability of technology-based startups and venture companies. As a result of analyzing 135 special technology companies listed from 2005 to 21 (excluding SPAC mergers and foreign companies) whether or not related personnel affect corporate value and listing period when they are listed, it was analyzed that the presence of related personnel did not significantly affect corporate value or listing period. The same was found in the results of the verification by reducing the scope to related personnel such as public officials and related agencies. However, under certain conditions, significant results were derived from the presence of related personnel on the listing of companies listed in special technology cases. It was found that the presence of related personnel and VC investment had a significant effect on corporate value, and in the case of bio-industry, there was a slight significant effect on the duration of listing. This study is significant in that it systematically analyzed the signal effect of the existence of related personnel for the first time for all 135 companies. In addition, as a result of the analysis, the results suggest that internalized efforts to secure technology and marketability are more important, such as parallel to VC investment, rather than simply recruiting related personnel.

Reading "Money": Value and Signification of Money (화폐 읽기: 화폐의 의미작용과 가치)

  • Won, Yong-Jin;Hong, Sung-Il
    • Korean journal of communication and information
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    • v.41
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    • pp.75-107
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    • 2008
  • The paper aims to figure out the meaning of money in terms of communication in which we can find the specific communicative and cultural form of money. In the modern capitalist society, we cannot limit money within the economical terms - for example, store of value, medium of exchange, unit of account and means of payment - because money mediates all human activities beyond the economic boundary and conveys specific meaning in the social and the cultural area. Money can be the medium of the cultural and the communicational as well as the medium of the economic. In this respect, we've try to articulate money with linguistic or semiotic insight. Through this theoretical dialogue, we find two significations of money as a medium of communication. The first signification is meta-signification which drives the individual to the unlimited accumulation of the money. Meta-signification displace the second signification of the money that is the singular, over-determined and the mosaic significations. In this process money can be the signifier without signification. And then, money is the Master signifier which all sign should be identified imaginary. Finally, Money is not only the re-presense (Darstellung) of all sings but also the representative (Vertretung) of all signs. But this double position creates some tensions and makes master signifier of money unstable. Man's analysis of Bonapartism, which shares the linguistic or semiotic insight, shows the crack of the re-presence between the representative. Like Marx's analysis, the money has the tension between two signification which makes the room for the struggle to signify.

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A PRELIMINARY STUDY OF CHILDREN WITH LEARNING DISORDER IN KOREA (한국에서의 학습장애 아동에 대한 예비적 연구 - 종합병원 학습장애 특수 클리닉 내원 아동을 중심으로 -)

  • Kim, Seung-Tai;Kim, Ji-Hae;Hong, Sung-Do;Joung, Yoo-Sook
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.7 no.2
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    • pp.247-257
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    • 1996
  • This is a preliminary report on the first segment of a continuing and prospective teaming disorder study project in Korea. Study subjects were 197 children, aged between 6 and 15 referred for psychiatric evaluation of scholastic problems. Demographic data, psychiatric diagnoses and intelligence and achievement test results were reviewed and analyzed. Analyses of data lead to the following conclusions : (1) About 20.8% of children referred for scholastic problems were diagnosed of teaming disorder(LD). The most prevalent diagnosis among these children with scholastic problem was emotional disorder, especially depressive disorder(33%), (2) The comorbid rate of attention deficit/hyperactivity disorder(ADHD) of 41 children with LD was 44%, (3) Male/female ratio was 5.8:1 among all of the LD children, 17:1 among children with LD and ADHD and 3.6:l among children with LD but without ADHD, (4) 83% of children with LD scored above middle level on socioeconomic status(SES), (5) Age, SES, IQ, family psychiatric history, past history of medical and psychiatric illness, onset of age, pattern of peer relationship, number of friends, presence of adaptation problem and academic achievements of children with LD and ADHD compared to those of children with LD but without ADHD. No significant differences between two groups were found on age, SES, IQ, family psychiatric history, past history of medical and psychiatric illness, pattern of peer relationship, number of friends and presence of adaptation problem. However, there were significant differences in academic achievements of Korean language total, speaking and listening score, arithmetic score, social science score and music score of children with LD and ADHD compared to those of children with LD but without ADHD. Also there was an ealier onset of age in LD and ADHD group when compared to LD but without ADHD group.

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Survey on organizational structures of clinical dental hygienists (임상 치과위생사의 직제실태 조사)

  • Noh, Hie-Jin;Bae, Sung-Suk;Kim, Seon-Kyeong;Mun, So-Jung;Han, Sun-Young;Cho, Hyo-Soon;Nam, Jeong-Ran;Kim, Seong-Ok;Kim, Bo-Kyoung;Chung, Kyung-Yi
    • Journal of Korean society of Dental Hygiene
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    • v.17 no.1
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    • pp.169-179
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    • 2017
  • Objectives: The present study is aimed at comprehending the organizational setup of clinical dental hygienists and to establish an organizational setup that fits their roles. Methods: The survey data of 776 clinical dental hygienists who understood the purpose of the study and agreed to write the questionnaire was utilized. Statistical analysis was performed using SPSS Ver. 20.0 program and the significance level was 0.05. Results: The presence of an organizational setup in dental hygienists was surveyed as being higher, with university dental hospital (89.86%) showing the highest. However, the presence of position terms was highest in dental hospitals with 76 subjects (38.78%). Standards for positions most commonly followed hospital regulations in the case of general hospitals (48.42%), whereas they were often based on service period in the case of dental hospitals (48.90%). Salary standards were most commonly determined by service period in all institutions. The job satisfaction of dental hygienists was significantly different according to social status and financial satisfaction depended on having organizational hierarchy for those who work in university dental hospitals. Conclusions: The results of the present study show that dental hygienists who work in organizational setups mostly enjoy high satisfaction in terms of job satisfaction. In other words, the study shows that systemizing the organizational setup of dental hygienists within dental institutions is required, and additional research to achieve efficient human resource management within the organization is necessary as well as institutional utilization of the results of the present study.

Effects of Facial Expression of Others on Moral Judgment (타인의 얼굴 표정이 도덕적 판단에 미치는 영향)

  • Lee, WonSeob;Kim, ShinWoo
    • Korean Journal of Cognitive Science
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    • v.30 no.2
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    • pp.85-104
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    • 2019
  • Past research showed that presence of others induces morally desirable behavior and stricter judgments. That is, presence of others makes people become a moral being. On the other hand, little research has been conducted to test what effects facial expression of others have on moral judgments. In this research, we tested the effects of emotion exposed by facial expression on moral judgments. To this end, we presented descriptions of immoral or prosocial behavior along with facial expression of various emotions (in particular, disgust and happiness), and asked participants to make moral judgments on the behavior in the descriptions. In Experiment 1, facial expression did not affect moral judgments, but variability of judgments was increased when descriptions and facial expression were incongruent. In experiment 2, we modified potential reasons of the null effect and conducted the experiment using the same procedure. Subjects in Experiment 2 made stricter judgments with disgust faces than with happy faces for immoral behavior, but the effect did not occur for prosocial behavior. In Experiment 3, we repeated the same experiment after having subjects to consider themselves as the actor in the descriptions. The results replicated the effects of facial expression in Experiment 2 but there was no effect of the actor on moral judgments. This research showed that facial expression of others specifically affects moral judgments on immoral behavior but not on prosocial behavior. In general discussion, we provided further discussion on the results and the limitations of this research.

Effect of self awareness of halitosis on the quality of life related to oral health in patients with chronic renal failure (만성신부전증 환자의 자가 구취인식이 구강건강관련 삶의 질에 미치는 영향)

  • Cho, Eun-Suk
    • Journal of Digital Convergence
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    • v.11 no.12
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    • pp.607-614
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    • 2013
  • This study has been conducted to investigate the effect of self awareness of halitosis on the quality of life related to oral health in patients with chronic renal failure undergoing hemodialysis and use basic data related to oral health of patients with chronic renal failure which is very rare in Korea. In terms of oral symptoms based on awareness of halitosis, there were significant differences in symptoms of teeth pain in the past one month, bleeding gums, symptoms of tongue or cheek pain, dry mouth, In terms of status of oral functions, there were significant differences in discomfort upon chewing foods, difficulty of pronunciation and presence of lost teeth. As the results of analysis of effect of self awareness of halitosis on the quality of life related to oral health in patients with chronic renal failure, it was shown that there were significant effects in psychological discomfort(B=-2.028, p<.01), poor social skills(B=2.596, p<.01) and social disadvantage(B=-2.173, p<.01). Thus, because self awareness of halitosis gives psychologically and socially negative effects, it could be an important factor to patients with renal failure whose number is rapidly increasing.

Identifying the Network Characteristics of Contributors That Affect Performance in Open Collaboration : Focusing on the GitHub Open Source (개방형협업 참여자 기여도와 네트워크 특성과의 관계에 대한 연구 : 깃허브 오픈소스 프로젝트를 중심으로)

  • Baek, Hyunmi;Oh, Sehwan
    • The Journal of Society for e-Business Studies
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    • v.20 no.1
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    • pp.23-43
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    • 2015
  • Information and communications technology facilitates collaboration among individuals by functioning as an open platform for open collaboration projects. In this regard, this study aims to understand the network characteristics of participants who contribute greatly to open collaboration by investigating the mutual cooperation network in an open source project, which represents a form of open collaboration based on social network theory. To achieve this objective, this study analyzes the network centrality of developers with a high number of commits, particularly 8,101 developers in 782 repositories in GitHub, a representative open source platform. This study also determines how the relationship between network centrality and number of commits depends on the size of a repository network and the presence of a hub. Consequently, the number of commits by developers with high degree, betweenness, and closeness centrality is increasing. Among which, betweenness centrality has the highest explanatory power. Furthermore, when a hub is present and as network size increases, the relationship between the betweenness centrality of a developer and his/her number of commits continues to grow. This study is expected to provide suggestions for the successful performance of open collaboration projects in the future.

Determinants of English Ability among Korean and Other Asian Immigrants in the US (미국에 거주하는 한국인과 아시아인들의 영어사용능력 결정요인에 관한 연구)

  • 이성우;민성희;김성수
    • Korea journal of population studies
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    • v.24 no.2
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    • pp.255-286
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    • 2001
  • The development of language skills among immigrants is important for their economic adjustment in their host societies since language is an important dimension of the skill levels of immigrants relevant for the labor markets of the host countries. Moreover, language plays a key role in the social adjustment of immigrants and in the social and political cohesion particularly in the society like the US that has diverse racial and ethnic groups. The main purposes of the present study are to analyze the determinants of English abilities of Korean and other Asian immigrants in the US. The present study utilizes the Public Use Microdata Sample (PUMS, S, 5%) in the US. We adopted the ordered probit technique to analyze qualitative differences of English ability. The study found that English fluency increases with a longer duration in the US, the presence of children in the household, living in an area in which a smaller proportion speak ones mother tongue, a younger age at immigration, a higher level of schooling. However, there are marked variations in levels of English proficiency among Asian immigrants.

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