• Title/Summary/Keyword: Social factor

Search Result 4,457, Processing Time 0.029 seconds

Effects of a gintonin-enriched fraction on hair growth: an in vitro and in vivo study

  • Lee, Na-Eun;Park, Sang-Deuk;Hwang, Hongik;Choi, Sun-Hye;Lee, Ra Mi;Nam, Sung Min;Choi, Jong Hee;Rhim, Hyewhon;Cho, Ik-Hyun;Kim, Hyoung-Chun;Hwang, Sung-Hee;Nah, Seung-Yeol
    • Journal of Ginseng Research
    • /
    • v.44 no.1
    • /
    • pp.168-177
    • /
    • 2020
  • Background: Ginseng has been widely used as a health-promoting tonic. Gintonin present in ginseng acts as a lysophosphatidic acid (LPA) receptor ligand that activates six LPA receptor subtypes. The LPA6 subtype plays a key role in normal hair growth, and mutations in the LPA6 receptor impair normal human hair growth. Currently, human hair loss and alopecia are concerning issues that affect peoples' social and day-to-day lives. Objective: We investigated the in vitro and in vivo effects of a gintonin-enriched fraction (GEF) on mouse hair growth. Methods: Human hair follicle dermal papilla cells (HFDPCs) and six-week-old male C57BL/6 mice were used. The mice were divided into the four groups: control, 1% minoxidil, 0.75% GEF, and 1.5% GEF. The dorsal hair was removed to synchronize the telogen phase. Each group was treated topically, once a day, for 15 days. We analyzed hair growth activity and histological changes. Results: GEF induced transient [Ca2+]i, which stimulated HFDPC proliferation and caused 5-bromo-2'-deoxyuridine (BrdU) incorporation in a concentration-dependent manner. GEF-mediated HFDPC proliferation was blocked by the LPA receptor antagonist and Ca2+ chelator. HFDPC treatment with GEF stimulated vascular endothelial growth factor release. Topical application of GEF and minoxidil promoted hair growth in a dose-dependent manner. Histological analysis showed that GEF and minoxidil increased the number of hair follicles and hair weight. Conclusion: Topical application of GEF promotes mouse hair growth through HFDPC proliferation. GEF could be one of the main components of ginseng that promote hair growth and could be used to treat human alopecia.

The Convergence effect of job stress of counselors on sexual orientation -Focusing on ego resilience- (성폭력 관련기관 상담원의 직무스트레스가 이직 의도에 미치는 융합적 영향 -자아탄력성 매개중심으로-)

  • Park, Yoo-Beom
    • Journal of Convergence for Information Technology
    • /
    • v.7 no.6
    • /
    • pp.193-199
    • /
    • 2017
  • The research is aimed at finding out the relationship between vocational stress and willingness to engage in vocational stress, which measures vocational stress and the ability to cope with the job, and how the job stress relates to job mobility. First of all, the job stress and willingness to transfer jobs related to sexual harassment related agencies have a positive correlation, while self-exploitation, job stress, and willingness to move jobs have shown negative correlation. Second, the self-assessment of self-assessment of ego resilience has served as a complete parameter in relation to the relationship between employee motivation and willingness to leave the job, which is the job of occupational duties. Based on this study, it is important to note that self-reference is an important factor in determining the role of job stress in the workforce because of its self-reference of job stress and motivation in relation to job stress.

New Service System Model According to Evolution of Service Concept (서비스 개념의 진화에 따른 신(新) 서비스 시스템 모델)

  • Lee, JeungSun;Kim, Hyunsoo
    • Journal of Service Research and Studies
    • /
    • v.7 no.2
    • /
    • pp.1-16
    • /
    • 2017
  • The service that has been recognized as both a non-productive activity and auxiliary activity of manufacturing have become the driving force of the customers' demand with the 'service' itself. The service base is expanding and evolving rapidly. It is important to look at changes in service concepts to understand service systems. Because the service system itself has a cyclic nature based on the concept of service, it can help in the study and the "how" of service by looking at changing the system according to the evolution of the service concept. The ability to organize and utilize relationships is considered to be an important factor for managers in the service economy era. However, the attention of corporate is focused on their internal capabilities and they are familiar with external resources (knowledge and competence of customers). In this case study for each type of service, we analyzed the activities of interacting service providers-consumers in service relationship, and constructed a new service system model emphasizing intangible value and long-term outcome. This study is worth re-examining the role of customers in today's service economy era and actively utilizing a new service model for business performance.

An Analysis and Improvement of Free Form Building's Construction Productivity - Focused on Exposed Concrete Work - (비정형 건축물 공사의 생산성 분석 및 향상방안 - 노출콘크리트 공사를 중심으로 -)

  • Lee, Eun-Young;Kim, Yea-Sang
    • Korean Journal of Construction Engineering and Management
    • /
    • v.15 no.3
    • /
    • pp.38-46
    • /
    • 2014
  • The Global's top five Design Firms selected from BauNetz a German architectural magazine in 2007 designed free form building design which was 25% of the overall design by 2006-2010. Free form building is a landmark of the city and the country so its social and economic impacts are very large. In case of Korea, free form buildings such as Tribowl in Incheon, KINTEX Exhibition hall 2 and Dongdaemun Design Plaza have increased. However, those the increase in design trends and, the needs due to the lack of free form building design and construction management experience, free form building projects can't be expected to profitability and have a number of problems after completion. Especially, there are many excessive quality problems and the rising cost due to design changes frequently and lack of experience and data. Thus an initial plan regardless of considering of free form building's characteristics can be a huge risk because of the difference with the plan and actual projects, yet there aren't free form building project's performance data and case studies related to productivity. In this study, through selection of low-construction productivity works and an analysis of the work process and productivity data, hope to propose an actual field productivity of free form building and the ways to improve productivity.

A Preliminary Study on Anxiety Inventory for Middle Graders at Elementary School (초등학교 중학년용 불안 검사 개발을 위한 예비 연구)

  • Kim, Sei-Young;Eun, Hyuk-Gi
    • The Korean Journal of Elementary Counseling
    • /
    • v.9 no.2
    • /
    • pp.195-215
    • /
    • 2010
  • The purpose of this study is to have a preliminary study in order to develop a test which can comprehensively measure anxiety of elementary schoolchildren in middle grade. Following things are conducted to meet this task; first, to look into compositions of the anxiety of elementary schoolchildren in middle grade, to prepare proper questions to measure it and to develop a test; second, to look into whether such questions are fully understood by schoolchildren; third, to look into whether reliability and adequacy thereof are proper or not. Conclusion of the study is as follows; anxiety test of elementary schoolchildren in middle grade showed all the things related to general anxiety, social anxiety, study anxiety, examination anxiety, announcement anxiety. However, there were differences as per subordinate factor and detailed area. And reliability and adequacy of anxiety test for elementary schoolchildren in middle grade were appropriate. and such data could be valuably used for preparing anxiety test. To summarize the study result above, the test developed in this study supplements weak point of existing test instrument and reveals anxiety experienced by elementary schoolchildren in middle grade, and harmoniously composes all the kinds. It is meaningful that the test lowered applicable object to schoolchildren in middle grade who are in anxiety formation stage and also feel anxiety most strongly. In addition, it may be used usefully for living guidance and consultation to efficiently cope with anxiety by measuring base line regarding anxiety of individual schoolchildren in middle grade.

  • PDF

The Effect Organizational Justice on Organizational Citizenship Behavior focus on Nurses in Secondary Hospitals (임상간호사의 조직공정성이 조직시민행동에 미치는 영향 : 2차 의료기관을 대상으로)

  • Chang, Kyung-Wha
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.16 no.11
    • /
    • pp.7648-7655
    • /
    • 2015
  • Nursing service quality can vary depending on the work attitude and behavior of nurses. Nursing attitude and behavior that can be described as voluntary and proactive organizational citizenship behavior(OCB). OCB affects the work performance of nurses in clinical practice is very important and organizational justice is an important influencing factors of OCB. The purpose of this study was to determine the influential factors of organizational justice on OCB of nurses. The descriptive-correlational method was applied. The study was carried out less than a 500-bed hospital. Participants of the study included 230 nurses working in secondary hospitals. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient and multiple regression with the 18.0 SPSS/Window program. Considering the components of organizational justice, there was a significant positive correlation(r=.172~.540, p=.000) between OCB and distributive, procedural and interactional justice. Also, Total organizational justice explained 29.1% of total OCB with influencing factor (${\beta}$=.540) and was statistically significant(F=93.777, p=.000). The influencing factors to OCB were distributive justice(${\beta}$=.283) and interactional justice(${\beta}$=.249) except procedural justice. The findings suggest that strategies of nursing management are needed to focus on distributive justice for compensation and interactional justice for social relationship in order to induce nurses' organizational citizenship behavior.

Nutrients Intake and Dietary Quality of Korean Parkinson's Disease Patients According to the Duration of Disease (유병기간에 따른 한국인 파킨슨병 환자의 영양소 섭취 상태 및 식사의 질에 관한 연구)

  • Lee, Ju-Yeon;An, Tae-Beom;Jeon, Beom-Seok;Kim, Yun-Young;Choue, Ryo-Won
    • Korean Journal of Community Nutrition
    • /
    • v.13 no.4
    • /
    • pp.582-591
    • /
    • 2008
  • Both genetic and environmental factors play important roles in the pathogenesis of Parkinson Disease(PD). The contribution of many environmental factors including dietary factor remains unproven. The purpose the study was to investigate the dietary habits, nutrient intake and dietary quality of Korean PD patients according to the duration of disease. PD patients were recruited from K and S university hospitals from May 2005 to January 2006. This study was carried out after approval by the Institute Review Board(IRB). British Brain Bank criteria was used to diagnose PD. The subjects were classified into 2 groups based on the duration of PD: <25 months and $\geq$25 months groups. General characteristics, anthropometric measurements, food habits and dietary intakes were investigated. The results of this study were as follows: 1) The mean age of <25 months group($66.9{\pm}8.0$ yr) was significantly higher than that of $\geq$25 months group($62.2{\pm}8.8$ yr)(p<0.05). No significant differences were found for academic background, occupation, living status and social activity, however, numbers of diseases, exercise and family history of PD were significantly different. 2) Anthropometric measurements were not different between the two groups. 3) The frequency of taking snacks was significantly higher in <25 months group and the amounts of alcohol consumption were significantly higher in $\geq$25 months group. 4) Daily intakes of most nutrients were very low compared with DRI. 5) The MAR score was significantly lower in <25 months group(p<0.05;) however, the scores of DVS, DDS and DQI were not significantly different. As a conclusion an overall nutrient intake and dietary quality of the Parkinson's Disease patients need to be improved regardless of duration of the disease and a well-balanced diet should be emphasized.

Impact of School Violence on Psychological Well-being: Korean Students' Happiness and Suicidal Impulse (한국 청소년의 학교폭력 경험과 심리적 안녕 -주관적 행복감과 자살충동을 중심으로-)

  • Kim, Kyungmi;Youm, Yoosik;Park, Younmin
    • The Journal of the Korea Contents Association
    • /
    • v.13 no.9
    • /
    • pp.236-247
    • /
    • 2013
  • This study examines the impact of school violence on South Korean students' psychological well-being. The research is designed to analyze how different types of experiences of school violence-victim, perpetrator, victim-perpetrator, and non-involvement-influence students' suicidal impulse and sense of happiness. Empirical data was gained from a national-scale survey conducted by Social Development Research Institute at Yonsei University in 2013, and was analyzed using binary logistic and multiple regression methods. Findings suggest that any types of experiences of school violence had significant effect on suicidal impulse. In particular, the likelihood of victim-perpetrator to experience suicidal impulse was 7.1 times stronger than non-involvement. However, the effect of experiences of school violence on students' sense of happiness was insignificant. While the impact of school violence on sense of happiness among victims and victim-perpetrators was significant, its impact among perpetrators proved insignificant. Rather, stress factor-in particular, stress from peers-had more significant impact on the level of students' happiness. This study contributes to understanding the multiple effect of school violence by examining both negative and positive dimensions of psychological well-being.

Floating Photovoltaic Plant Location Analysis using GIS (GIS를 활용한 수상 태양광 발전소 입지 분석)

  • Lee, Ki Rim;Lee, Won Hee
    • Journal of Korean Society for Geospatial Information Science
    • /
    • v.24 no.1
    • /
    • pp.51-59
    • /
    • 2016
  • Global consumption of fossil fuels continues to increase. As developing countries use fossil fuel as much as the existing fossil fuel using countries, the total amount of fossil fuel consumed has risen. The finite fossil energy depletion insecurity have become serious. In addition, fossil energy is caused by environmental pollution, economic and social problems remain in assignments that need to be addressed. Although solar power is clean and has many benefits, there are several problems in the process of installing a solar power plant. To solve these problems, floating photovoltaic plants has emerged as an alternative. This floating photovoltaic plants location analysis has not been made yet. In this study, the conditions of the floating photovoltaic plants location is analyzed with the Analytic Hierarchy Process using the terrain and climate factors. The score is assigned to the attribute information of each factor by the classification table. After multiplied by the weight the result is analyzed by visualization of the score. As the result, the score of the northen part of Gyeongsangbuk-do province is higher than the southern part of Gyeongsangbuk-do province. Especially Andongho lake in Andong City and the reservoir in Yeongyang-Gun are extracted as the optimal location. The score of the river boundary is low not the center of the river stream. It is expected that this study would be a more accurate floating solar power plant location analysis.

Metaphorical Analysis on Role Playing of Day Care Center Teachers (역할놀이에 대한 어린이집 교사의 은유분석)

  • Lim, Jin-Hyung;Lee, Jin-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.18 no.2
    • /
    • pp.524-531
    • /
    • 2017
  • Summary The purpose of this study was to understand the tendency and the meaning of day care center teachers regarding role playing through metaphorical analysis. The data were collected from 166 day care center teachers who participated in A-city university supplement education using the sentence completion metaphorical method. The collected data were categorized and analyzed through a qualitative research method conducted by 2 early childhood education specialists. The results are as follows. First, the tendency of role playing metaphorical expression was divided into 3 categories, 8 contents and the frequency of 'sociality development' was the highest followed by 'emotional development', 'development'. Second, the meaning of role playing metaphorical expression was recognized as 'social skills', 'role experience', 'imitation', and 'understanding of society' in the 'sociality development' category; as 'imagination', 'purification function', and 'means of expression' in the 'emotional development' category; and as 'essential factor of development' in the 'development' category. Based on the research result, it was suggested that the roles of education and teachers for the value and effective operation of role playing in early childhood education institutes should be reconsidered.