• 대한건축학회논문집:계획계
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• 제35권8호
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• pp.57-64
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• 2019

This study attempts to analyse the effects of high-rise living on suicide rates. All the apartments in the City A and every suicide were examined in detail. Research methods are as follows. First, a database including tenure type and number of residents in all apartment complexes was created. Second, apartments were categorized into two income groups of private apartments and social housing, and spatial configuration characteristics of a typical apartment were analysed. Third, differences in suicide rates were analysed for lower and upper levels in both apartment categories. Finally, the relationship between high and lower levels of apartments with their spatial configuration characteristics and suicide rates was compared. The analysis shows significant differences between lower and upper floors living residents' suicide rates. It can be stated that the low-income residents are more sensitive to living in high-rise environment. Also, it suggests the need to improve the high-rise living environment of vulnerable social groups. In addition, spatial integration decrease in upper floors of high-rise buildings, and it can be interpreted that spatial configuration may affect residents' pathological disorders or even suicidal behaviors.

• 신경정신의학
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• 제57권2호
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• pp.190-208
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• 2018

Objectives To initiate and develop a treatment guideline in multidisciplinary approaches for related professions who are either working and/or living with children and adolescents with neurodevelopmental disorders who show behavioral problems. Methods To collect and reflect opinions from multiple professions who assumedly have different interventions or mediations on behavioral problems, a self-report survey and Focus Group Interview (FGI) were conducted for a group of child and adolescent psychiatrists, behavioral therapists, special education teachers, social welfare workers, and caregivers. Results According to a self-report survey and FGI results from multiple professional groups, aggressive behavior is the mostly common behavioral problem necessitating urgent interventions. However, both mainly used intervention strategies and effective treatment methods were different depending on professional backgrounds, such as pharmacological treatment, parent training, and behavior therapy, even though they shared an importance of improving communication skills. In addition, there was a common understanding of necessity to include parent training in a guideline. Lastly the data suggested lack of proper treatment facilities, qualified behavior therapists, and lack of standardized treatment guideline in the field needed to be improved for a quality of current therapeutic services. Conclusion It is supported that several subjects should be included in the guidelines, such as how to deal with aggressive behavior, parent training, and biological aspects of neurodevelopmental disorders. Also, it is expected that publishing the guideline would be helpful to above multiple professions as it is investigated that there are lack of treatment facility and qualified behavioral therapists compared to need at the moment.

• The Korean Journal of Physiology and Pharmacology
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• 제23권6호
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• pp.467-474
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• 2019

Exposure to lead during pregnancy is a risk factor for the development of psychiatric disorders in the offspring. In this study, we investigated whether exposure to low levels of lead acetate (0.2%) in drinking water during pregnancy and lactation causes behavioral impairment and affects the expression of proteins associated with neurodevelopment. Lead exposure altered several parameters in rat offspring compared with those unexposed in open-field, social interaction, and pre-pulse inhibition tests. These parameters were restored to normal levels after clozapine treatment. Western blot and immunohistochemical analyses of the hippocampus revealed that several neurodevelopmental proteins were downregulated in lead-exposed rats. The expression was normalized after clozapine treatment (5 mg/kg/day, postnatal day 35-56). These findings demonstrate that downregulation of several proteins in lead-exposed rats affected subsequent behavioral changes. Our results suggest that lead exposure in early life may induce psychiatric disorders and treatment with antipsychotics such as clozapine may reduce their incidence.

• ETRI Journal
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• 제44권4호
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• pp.613-623
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• 2022

Autism spectrum disorder (ASD) is a developmental disorder associated with cognitive and neurobehavioral disorders. It affects the person's behavior and performance. Autism affects verbal and non-verbal communication in social interactions. Early screening and diagnosis of ASD are essential and helpful for early educational planning and treatment, the provision of family support, and for providing appropriate medical support for the child on time. Thus, developing automated methods for diagnosing ASD is becoming an essential need. Herein, we investigate using various machine learning methods to build predictive models for diagnosing ASD in children using facial images. To achieve this, we used an autistic children dataset containing 2936 facial images of children with autism and typical children. In application, we used classical machine learning methods, such as support vector machine and random forest. In addition to using deep-learning methods, we used a state-of-the-art method, that is, automated machine learning (AutoML). We compared the results obtained from the existing techniques. Consequently, we obtained that AutoML achieved the highest performance of approximately 96% accuracy via the Hyperpot and tree-based pipeline optimization tool optimization. Furthermore, AutoML methods enabled us to easily find the best parameter settings without any human efforts for feature engineering.

• 인간행동과 음악연구
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• 제13권1호
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• pp.61-87
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• 2016

자폐범주성장애 아동은 사회적 의사소통 발달에 있어 넓은 범주의 개별적 변이성을 보이기 때문에 이에 대한 중재 개입 시 효과적인 전략이 매우 중요하며, 이를 정확하게 평가할 수 있는 사회적 의사소통 평가도구의 중요성이 지속적으로 강조되고 있다. 본 연구에서는 음악 중재 문헌 내에서 사용된 사회적 의사소통 측정 도구에 대해 고찰하고 이를 분석하였다. 전자데이터베이스 및 음악치료 학술지 검색을 통해 자폐범주성장애 아동의 사회적 의사소통을 변인으로 한 중재 연구 중 1980년에서 2015년까지 출간된 통제된 디자인의 연구가 검색되었고, 최종 분석에는 21개의 연구가 포함되었다. 분석 결과, 측정 도구 유형으로는 행동 직접 관찰이 가장 많이 사용되었고, 측정 도구 유형과 그에 따른 목표 영역 간 조합에 있어 변이성이 크게 나타났다. 또한 선정된 연구 중 90.4%를 차지하는 연구에서 측정 도구 사용의 적절성 검증을 위한 평가자 간 신뢰도가 보고되고 있음이 나타났다. 이러한 결과는 음악치료 중재문헌 내에서 객관적, 체계적 평가 시도가 증가함에도 불구하고, 동일 기능 수준에 접근하는 개별 연구 간 평가 방안 및 전략에 있어 일관성이 떨어지고, 이로 인한 임상근거 도출에 제한이 있음을 시사한다. 결론적으로 자폐범주성장애의 고유한 특성을 고려하여, 사회적 의사소통 평가 시 전반적 기능 수준 변화뿐만 아니라 특정한 행동 습득, 사회 인지 수준 등을 고려할 필요가 있음을 제언하였다.

• Molecules and Cells
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• 제41권5호
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• pp.486-494
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• 2018

Recently, we have reported that animals with telomerase reverse transcriptase (TERT) overexpression exhibit reduced social interaction, decreased preference for novel social interaction and poor nest-building behaviors-symptoms that mirror those observed in human autism spectrum disorders (ASD). Overexpression of TERT also alters the excitatory/inhibitory (E/I) ratio in the medial prefrontal cortex. However, the effects of TERT overexpression on hippocampal-dependent learning and synaptic efficacy have not been investigated. In the present study, we employed electrophysiological approaches in combination with behavioral analysis to examine hippocampal function of TERT transgenic (TERT-tg) mice and FVB controls. We found that TERT overexpression results in enhanced hippocampal excitation with no changes in inhibition and significantly impairs long-term synaptic plasticity. Interestingly, the expression levels of phosphorylated CREB and phosphorylated $CaMKII{\alpha}$ were significantly decreased while the expression level of $CaMKII{\alpha}$ was slightly increased in the hippocampus of TERT-overexpressing mice. Our observations highlight the importance of TERT in normal synaptic function and behavior and provide additional information on a novel animal model of ASD associated with TERT overexpression.

• Industrial Engineering and Management Systems
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• 제11권2호
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• pp.142-147
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• 2012

Individuals with autistic spectrum disorders (ASD) have difficulty inferring other people's feelings from their facial expressions and/or from situational cues, and therefore, they are less able to respond with prosocial behavior. We developed a computer-based training program to help teach the connection between facial-based or situation-based emotions and prosocial behavioral responses. An 8-year-old male school child with ASD participated in the study. In this program, he was trained to identify persons in need of help and appropriate prosocial responses using novel photo-based scenarios. When he misidentified emotions from photographs of another's face, the program highlighted those parts of the face which effectively communicate emotion. To increase the likelihood that he would learn a generalized repertoire of emotional understanding, multiple examples of emotional expressions and situations were provided. When he misidentified persons expressing a need for help, or failed to identify appropriate helping behaviors, role playing was used to help him appreciate the state of mind of a person in need of help. The results of the training indicated increases in prosocial behaviors during a laboratory task that required collaborative work. His homeroom teacher, using a behavioral rating scale, reported that he now understood another's emotion or situation better than before training. These findings indicate the effects of the training are not limited to the artificial experiment situation, but also carried over to his school life.

• 대한한방소아과학회지
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• 제16권1호
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• pp.105-124
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• 2002

With the progress of civilization, the disorders due to the stress, which derived from the social-structural complexity and diversity, are on an increasing trend in our times. Accordingly, the accurate diagnosis and appropriate treatment for them are required. Especially in the current years, children's disorders delivered by the emotional problems keep increasing. In this research, the researcher tried to figure out the cause of the children's stress and its treatment, studied the theories of the stress in the modem medicine and the sever emotions in oriental medicine, and came to the conclusion as follows: 1. The stress can be defined as the combination of the reaction to noxious stimuli and its defense mechanism of the body, In oriental medicine, it is considered as pathological notions which includes seven emotions as the internal factor, six evils as the external factor and other foods, expectoration, ecchymoma as the non-internal/external factors. 2. Children usually get stressed by various reasons in a growth process such as schooling, relationship with friends, the opposite sex of family, or change of surroundings, and these can cause the various disorders. 3. In the study of the children's stress symptoms, it is found that the silent reaction is uncommon. It usually appeared in both reactions: firs, physical reactions such as stomachache, vomiting, headache, neural frequent urination, bronchial asthma or excessive respiration and/or, second, behavioral reactions such as a decline of performance, alimentary disorder, e.g. anorexia nervosa or bulimia, sleep disorder, e.g. nightmare or panic in sleep, anthrophobia, refusal to a school attendance or hyperactiveness. Besides, the peculiar mental disorder such as paroxysm of anger, tic, autism, nocturnal enuresis, lack of attentiveness, impediment in linguistic development, learning difficulty, intellectual decline, etc. can be appeared, and the heavy stress during the babyhood can cause the regression of behavior or the immaturity of formation of character. 4. The appropriate treatments for the children's stress are Osteopathy, Manpulation, Aroma Therapy, Alexander Technique, Autonomic Never Control Treatment, Biofeedback, Chiropractic, Dance Therapy, Feldenkrasis Technique, Gravity Therapy, Homepathy, Aquatherapy, Hypnotherapy, Naturopathy and Meditation.

• 재활치료과학
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• 제11권4호
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• pp.41-53
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• 2022

목적 : 본 연구는 정신장애인의 직업재활 평가도구를 확인하고 분석함으로써 작업치료 영역에서 임상적으로 유용하게 활용할 수 있는 정신장애인 직업재활 평가도구의 개발을 위한 기초자료로 활용하는 것이다. 연구방법 : 문헌 검색은 Pubmed 데이터베이스를 사용하였으며, 분석 내용은 개발연도, 평가방식, 문항 수, 척도, 평가 문항을 분석하였다. 분석 방법은 각 평가 항목을 기능, 내적요인, 환경, 정신증상의 4가지 범주로 구분하여 각 평가도구의 평가 요소에 대해 파악하였다. 결과 : 검색어를 통한 Pubmed 검색 시 161개의 문헌이 검색되었고, 선정 방법에 따라 Griffiths Work Behavior Scale (GWBS), Occupational Functioning Scale (OFS), Social and Occupational Functioning Assessment Scale (SOFAS), Work Ability Index (WAI), Work Behaviour Inventory (WBI), Work Environment Impact Scale (WEIS), Work and Social Adjustment Scale (WSAS)의 7개 평가도구가 선별되었다. 모든 평가도구의 평가항목은 직무와 관련된 기능평가를 포함하였으며, 각 평가도구의 목적에 따라 내적요인, 환경, 정신증상에 대한 측정이 이루어지는 것으로 나타났다. 결론 : 직업 기술은 신체, 인지, 사회기술, 대처능력 등 다양한 기능이 복합적으로 작용하는 기술이다. 따라서 본 연구에서 분석한 기능, 내적요인, 환경, 정신증상의 4가지 요소가 포함될 필요가 있으며, 평가과정에서 발생하는 물리적 제약을 보완하기 위해 ICT 융합 평가도구의 개발함으로써 보다 효율적인 정신장애인 직업재활 평가가 이루어져야 할 것이다.

• 혜화의학회지
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• 제8권2호
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• pp.329-339
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• 2000

I got the following result from the bibliographic study of disease in relation to sexual psychology. The results are follows. 1. Sexual disorder is divided sexual disfunction, paraphilias, gender identity disorder, homosexuality and that is subdivided fetishism, transvestic fetishism, pedophilia, exhibitionism, voyerism, sexual masochism, sexual sadism, frotteurism, gender identity disorder of childhood, gender identity disorder of youth and adult, intersexual disorders. 2. In korean oriental medicine mainly refer to sexual disfunction, and sexual psychological disorder include Hwajeon(花癲), Buinmongio(婦人夢交), Guabusani disease(寡婦師尼病). 3. Social psychologic cause and, oedipus complex, sexual hormone induce sexual psychological disorder but in korean oriental medicine, recognized sexual psychological disorder place under the category of sexual disfunction. 4. The latest medicine has various medical treatment in sexual disorder as avoidence conditioning, medication, role playing, behavior modification, psychoanalysis theraphy but in korean oriental medicine has only medication theraphy, so need more introduction of medical treatment.