• Title/Summary/Keyword: Social Sciences Research

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Prevalence of HER-2-Positive Invasive Breast Cancer: A Systematic Review from Iran

  • Keyhani, Elahe;Muhammadnejad, Ahad;Karimlou, Masoud
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5477-5482
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    • 2012
  • Background: The HER-2/neu gene is altered in 15-20% of breast cancer patients. Immunohistochemistry (IHC) is considered to be the most cost-effective method for HER-2 detection in many countries. Approximately 8,000 new cases of breast cancer are observed annually in Iran. The aims of this study were to conduct a systematic review of the literature on the rate of HER-2-positive breast cancer diagnosed by IHC in Iran. Methods: A systematic search of the medical literature using the Medline/PubMed, ISI and SID databases revealed articles published in the English and Persian languages evaluating HER-2-positive breast cancer in Iran. Results: From 22 studies, 3,033 patients were evaluated, of whom 1,350 were diagnosed as HER-2-positive by IHC HER-2 testing. The mean percentage of HER-2-positive patients was 44.5%, which is higher than that recorded in international statistics. Results of this meta-analysis showed a significant heterogeneity between ratios. There was a statistically significant difference between the results of pre- and post implementation of 2007 American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) guideline. IHC HER-2 testing has been performed in Iran for over 10 years. Similar to many other countries, before establishment of an infrastructure for IHC diagnostic tests, HER-2 testing was routinely performed in Iran. Our study showed that the statistics reported from Iran varied widely; for instance, the rate of HER-2-positive cases varied from 23.3% to 81.0%. Conclusions: Our results demonstrate that the lack of standardization and harmonization of this test have led to marked variations in breast cancer diagnosis in Iran.

Psychological Effects of Elderly Activities Interacting with Interacting with Oriental Garden Cricket (곤충체험을 통한 치유농업의 심리치유효과 -왕귀뚜라미 사례 -)

  • Kim, So-Yun;Park, Haechul;Park, In-Gyun;Kim, Seong-Hyun
    • Journal of Agricultural Extension & Community Development
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    • v.25 no.2
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    • pp.99-110
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    • 2018
  • Research confirms that healthful benefits accrued when people connect with nature and insect by viewing and interacting with them. Insect rearing is easy, relatively inexpensive, and can breed small space. This study aimed to investigate the physiological effects of animal assisted activity using insect(Oriental garden cricket) with diets and a rearing manual. The group of insect activity whose ages ranged from 65 to 82 years old that attending a community center in Daegu, Korea, were enrolled in the study between April and May 2014. The collected data was analyzed using qualitative analysis. Qualitative study is utilized to explore mental models, and their linguistic, affective, cognitive, social and cultural significance. The result showed that people-insect interactions promote well being of the elders, and the important aspect of insect activity aids in improvements in their social, emotional and cognitive functioning which were enhancing life satisfaction, reducing loneliness and increasing activities of daily life.

A Review on Renal Toxicity Profile of Common Abusive Drugs

  • Singh, Varun Parkash;Singh, Nirmal;Jaggi, Amteshwar Singh
    • The Korean Journal of Physiology and Pharmacology
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    • v.17 no.4
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    • pp.347-357
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    • 2013
  • Drug abuse has become a major social problem of the modern world and majority of these abusive drugs or their metabolites are excreted through the kidneys and, thus, the renal complications of these drugs are very common. Morphine, heroin, cocaine, nicotine and alcohol are the most commonly abused drugs, and their use is associated with various types of renal toxicity. The renal complications include a wide range of glomerular, interstitial and vascular diseases leading to acute or chronic renal failure. The present review discusses the renal toxicity profile and possible mechanisms of commonly abused drugs including morphine, heroin, cocaine, nicotine, caffeine and alcohol.

Organizational Change Readiness, Service Innovation, and Corporate Image in Improving Competitiveness: A Case Study in Indonesia

  • HUTAPEA, John Gunung;NIMRAN, Umar;IQBAL, Mohammad;HIDAYAT, Kadarisman
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.3
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    • pp.683-693
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    • 2021
  • Shipping has become an important sector in supporting social, economic, government, defense, security, cultural and other sectors to unite separate islands and broad seas. Thus, ports automatically become an important facility in Indonesia. The purpose of this research is to test and explain the effect of Organizational readiness for change, Service Innovation, and Corporate Image on Perceived opportunity and challenge. The research model with inferential analysis uses Structural Equation Modeling (SEM) analysis with the WarpPLS approach, expected to answer the statements of problem and be able to test the desired hypothesis. The model development in this research was based on the background, statements of problem, conceptual framework and research hypotheses. The model referred to is "Complete and Comprehensive Port." Its development was carried out through studying and synthesizing various sources. The most important source is the results of literature review in the form of theoretical developments and research results, then continued with compilation. The use of Organizational Change Readiness, Service Innovation, and Corporate Image in improving Port Competitiveness is seen as one of the novelties of this research, specifically the use of the Organizational Change Readiness variable which is often used in high-flexibility companies but now used in port companies as well.

Occupational Performance of Hearing-Impaired and Normal-Hearing Workers in Korea

  • Kim, Jinsook;Shin, Yerim;Lee, Seungwan;Lee, Eunsung;Han, Woojae;Lee, Jihyeon
    • Journal of Audiology & Otology
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    • v.25 no.4
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    • pp.189-198
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    • 2021
  • Background and Objectives: This study aimed to investigate the occupational performance of Korean workers with and without hearing loss and analyze the hearing-related difficulties in the working environment. Subjects and Methods: The Amsterdam checklist for hearing and work was used for the analyses and the occupational environments of the Korean workers were investigated. Out of 129 total participants, 86 workers experienced severe to profound hearing loss and 43 had the normal hearing ability. The hearing-impaired workers were recruited from two leading vocational centers and normal-hearing workers were their colleagues. Results: The hearing-impaired workers were found to take fewer sick leaves and exhibited higher rates of permanent job statuses compared to the normal-hearing workers. Workers with hearing loss rarely detected background sound; however, they could perceive reverberation more frequently. They felt more satisfied with their careers than the normal hearing workers as they received social support and needed to put their effort into hearing for most hearing activities. Furthermore, the effort in hearing increased with the increase in job demand, job control, social support, and career satisfaction. The working hours per week increased with the increase in age, education level, job demand, job control, and social support. Different trends were observed in 9 out of 12 variables while comparing the data from the present study with that obtained from the hearing-impaired workers of the Netherlands, indicating a large difference between countries. Conclusions: Although the hearing-impaired Korean workers operate diligently with good job positions, it is necessary to enhance their acoustic environment and provide them social support. Considering the cultural background of the hearing-impaired workers, the development of suitable vocational rehabilitation programs and specific questionnaires is strongly recommended worldwide.

Occupational Performance of Hearing-Impaired and Normal-Hearing Workers in Korea

  • Kim, Jinsook;Shin, Yerim;Lee, Seungwan;Lee, Eunsung;Han, Woojae;Lee, Jihyeon
    • Korean Journal of Audiology
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    • v.25 no.4
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    • pp.189-199
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    • 2021
  • Background and Objectives: This study aimed to investigate the occupational performance of Korean workers with and without hearing loss and analyze the hearing-related difficulties in the working environment. Subjects and Methods: The Amsterdam checklist for hearing and work was used for the analyses and the occupational environments of the Korean workers were investigated. Out of 129 total participants, 86 workers experienced severe to profound hearing loss and 43 had the normal hearing ability. The hearing-impaired workers were recruited from two leading vocational centers and normal-hearing workers were their colleagues. Results: The hearing-impaired workers were found to take fewer sick leaves and exhibited higher rates of permanent job statuses compared to the normal-hearing workers. Workers with hearing loss rarely detected background sound; however, they could perceive reverberation more frequently. They felt more satisfied with their careers than the normal hearing workers as they received social support and needed to put their effort into hearing for most hearing activities. Furthermore, the effort in hearing increased with the increase in job demand, job control, social support, and career satisfaction. The working hours per week increased with the increase in age, education level, job demand, job control, and social support. Different trends were observed in 9 out of 12 variables while comparing the data from the present study with that obtained from the hearing-impaired workers of the Netherlands, indicating a large difference between countries. Conclusions: Although the hearing-impaired Korean workers operate diligently with good job positions, it is necessary to enhance their acoustic environment and provide them social support. Considering the cultural background of the hearing-impaired workers, the development of suitable vocational rehabilitation programs and specific questionnaires is strongly recommended worldwide.

Influence of Peer Body Shape Norm and Peer Pressure Related to Body Shape on Social Media on Body Image Over-distortion of Early Adolescent Girls (소셜미디어 내의 또래 체형규범과 체형관련 또래압력이 초기 여자 청소년의 신체이미지 과대왜곡에 미치는 영향)

  • Jeeyeon Hong;Dooyoung Kim;Yoon Kyung Kim;Ju Hee Park
    • Human Ecology Research
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    • v.62 no.3
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    • pp.441-453
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    • 2024
  • This study aimed to explore the characteristics of early adolescent girls with an over-distorted body image and to examine the influence of peer descriptive norm and peer injunctive norm related to body shape and peer pressure for thinness on social media on body image over-distortion. The participants were 505 female adolescents in the 1st and 2nd grades of middle school. Descriptive statistics, frequency analysis, and binary logistic regression were used to analyze the data with SPSS 26.0. The results were as follows. First, the body image over-distortion group contained more 2nd-grader early adolescent girls than 1st graders and approximately three-quarters of the body image over-distortion group had previously attempted to lose weight. Second, peer pressure for thinness on social media significantly predicted whether early adolescent girls were in the body image over-distortion group compared to the non-distortion group. These outcomes suggest that it is necessary to create a social media culture that encourages early adolescent girls to have a realistic and healthy body shape. The results also highlight the importance of developing social media literacy education programs that inform early adolescents of the potential harm of negative comments on social media, and teach them how to recognize and dismiss indiscriminate and harmful comments and contents on social media.

Participation of the Women Covered by Family Physicians in Breast Cancer Screening Program in Kerman, Iran

  • Jafari, Mohammad;Nakhaee, Nouzar;Goudarzi, Reza;Zehtab, Nooshin;Barouni, Mohsen
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.11
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    • pp.4555-4561
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    • 2015
  • Background: Mammography screening is a method for reducing breast cancer mortality in women over 40 years old. A participation rate of at least 70% is a prerequisite for screening programs. This study aimed at determining the participation rate of women in breast cancer screening in Iran. Materials and Methods: The study population in this prospective research consisted of 35 to 69 years old women in the villages and towns Kerman District, in 2013. The data were collected by a well-validated risk assessment questionnaire. The questionnaires were completed with the help of health workers and technicians in the health centers, who were trained on breast cancer screening program. Results: As a whole, 19,651 women were invited to complete the questionnaire, of whom 15,794 women (80.37%) completed it. In the urban region, of 3150 eligible women 2728 women (86.60%) participated in the study. The acceptance rates for mammography in rural and urban regions were 34.95% and 8.75%, respectively. Conclusions: Finally, 3.8% and 16.34% of 35 to 69 years old women in the urban regions were mammographed, respectively. Conclusion: The low participation of eligible women in breast cancer screening program alerts us against including the program in the health insurance package.

Impact of skeletal divergence on oral health-related quality of life and self-reported jaw function

  • Antoun, Joseph Safwat;Thomson, William Murray;Merriman, Tony Raymond;Rongo, Roberto;Farella, Mauro
    • The korean journal of orthodontics
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    • v.47 no.3
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    • pp.186-194
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    • 2017
  • Objective: To investigate the differences in oral health-related quality of life (OHRQoL) and self-reported jaw function between patients with hyperdivergent and normodivergent facial types. Methods: Eighty patients with a distinctively hyperdivergent facial type (mandibular plane angle greater than 2 standard deviations, or $42^{\circ}$) and 80 controls were individually matched according to age, sex, ethnicity, and treatment stage. Data were collected using self-report questionnaires such as the Oral Health Impact Profile (OHIP-14) and Jaw Functional Limitation Scale (JFLS-8). Results: The mean age of the patients was $17.2{\pm}4.6years$ (range, 12-49 years), with most (65.0%) being female and of New Zealand European origin (91.3%). Individuals with hyperdivergent facial types had higher overall and social domain scores on the OHIP-14 (p < 0.05) than did the ones with normodivergent facial types. However, the intergroup differences in JFLS-8 scores were not significant (p > 0.05). Conclusions: Jaw function appears to be similar in individuals with hyperdivergent and normodivergent facial morphologies. However, those with hyperdivergent facial types are more likely to self-report poorer OHRQoL than are those with normal faces, especially in relation to social aspects.

Socialization and Health Experiences of Physical disabled Adults in Public Welfare Program (사회복지교육프로그램 참여 지체장애인의 건강과 사회화 경험)

  • KIM, Jeong-Soo
    • Journal of Fisheries and Marine Sciences Education
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    • v.28 no.1
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    • pp.258-265
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    • 2016
  • This study was to describe and understand the experiences of the physical disabled adult attending in public welfare program. The interview data were collected from seven persons and analyzed by using descriptive phenomenology of Colazzi. The procedural steps were that described the phenomenon of interest, collected participants' descriptions of the phenomenon, extracted the meaning of significant statements, organized the meanings into them clusters, wrote exhaustive descriptions and then incorporated data into an exhaustive description. The finding in 129 re-statements, 63 constructed meanings, 35 themes, 13 theme clusters, and six categories were deduced. The six categories were 'Life patterns exclusive health', 'Powerlessness by physical disabilities', 'Social supports', 'Positive motivation', 'Seeking to be holistic health', and 'Sense of accomplishment'. The study identified that social welfare program for the disabled necessities for health, learning, economy and their future in success. Therefore, we suggest there may be a need for supplying professional program for their health and welfare.