• Biomedical Science Letters
• /
• v.6 no.2
• /
• pp.109-118
• /
• 2000

The bronchus and alveoli from young rats have been examined by electron microscope following the exposure of cigarette smoking. Experimental animals were exposed to the sidestream smoke in an experimentally designed cage for 45 minutes per day during four weeks. In the smoking group, transmission electron micrographs of lung tissues showed a large number of neutrophils with electron densed several lysosomes, numerous macrophages with many small lysosomes, and many residual bodies in alveolar space. Scanning electron micrographs revealed that the ciliated epithelial cells in bronchus of smoking group were replaced by goblet cells including loss of cilia, and increased cell size of many goblet cells in bronchus. These results depicted that the ultrastructural changes are due to the passive smoking, involving airway cell Injury.

• Journal of Korean Academy of Fundamentals of Nursing
• /
• v.21 no.3
• /
• pp.253-263
• /
• 2014

Purpose: This study was done to explore the predictors asssociated with Korean women smokers' intentions to quit smoking. Methods: This study was a cross-sectional study including 3,578 women smokers. Data from the 2010 Community Health Survey conducted by the Korea Centers for Disease Control and Prevention were examined and analyzed using SPSS 21.0 for multiple logistic regression. Results: Of the women smokers 52.2% reported having an intention to quit smoking but only 3.9% had received education in smoking cessation. In the logistic analysis, factors associated with intention to quit smoking were age (Odds ratio and 95% [confidence interval]: 0.97 [0.96-0.98]), health-related quality of life (OR=2.39 [1.14-5.03]), perceived stress (OR=1.11 [1.00-1.22]), marital status (OR=0.93 [.86-1.00]), age of starting to smoke (OR=1.14 [1.04-1.24]), number of cigarettes per day (OR=0.84 [0.76-0.93]), exposure to smoking-quitting campaigns (OR=1.48 [1.22-1.80]), previous attempts at weight-control (OR=1.37 [1.15-1.63]), frequency of alcohol use (OR=1.16 [1.01-1.34]), hypercholesterolemia (OR=1.62 [1.18-2.24]), experiences of trying to quit smoking (OR=4.04 [3.45-4.73]), and regular medical check-up (OR=1.13 [1.03-1.43]). Conclusion: Identifying factors associated with the intentions to quit smoking provides possibilities for shaping effective policies and programs to increase smoking cessation among Korean women.

• Journal of Environmental Health Sciences
• /
• v.45 no.6
• /
• pp.605-612
• /
• 2019

Objectives: This study aims to examine receptor-perceived characteristics of environmental and health damage in areas surrounded by industrial workplaces using environmental complaints collected by local governments in Korea. Methods: The environmental complaint data related to workplaces was collected by local governments at each municipality between the years 2015 and 2017. We analyzed the complaint data from the Busan area by the type of business (industry classification), the content of complaints (odor, smoke, noise, and certain health damage), and the frequency of complaints. Results: Among the workplaces examined, industry categories related to retail and service received the highest frequency of complaints related to noise. On the other hand, complaints of dust and odors were raised in higher frequency against manufacturing industries, indicating that air pollution was the main driver of such complaints. Most of the complaints regarding health effects from industries also contained other complaints, such as odor, noise, and dust. Our results indicate that environmental discomfort can lead to more serious health damage, and should be dealt with more seriously. Further management plans for mitigating discomforts such as noise are necessary. Conclusion: This study can be used as background data for identifying the policy priorities related to vulnerable areas polluted by industry and will contribute to improving the environmental health of residents in identified areas.

• YAKHAK HOEJI
• /
• v.49 no.2
• /
• pp.174-179
• /
• 2005

The human skin is constantly exposed to environmental irritants such as ultraviolet, smoke, chemicals. Free radicals and reactive oxygen species (ROS) caused by these environmen tal facts play critical roles in cellular damage. These irritants are in themselves damaging to the skin structure but they also participate the immensely complex inflammatory reaction. The purpose of this study was to investigate the skin cell protective effect of Campsis grandiflora extract on the UVB-irradiated human dermal fibroblasts (HDFs). We tested free radical and superoxide scavenging effect in vitro. C. grandiflora extracts had potent radical scavenging effect by 82% at $100{\mu}g/ml$, respectively. For testing intracellular ROS scavenging activity the cultured HDFs were analyzed by increase in DCF fluorescence upon exposure to UVB 20 $MJ/cm^2$ after treatment of C.grandiflora extracts. The results showed that oxidation of CM-DCFDA was inhibited by C.grandiflora extracts effectively and C.grandiflora extracts has a potent free radical scavenging activity in UVB- irradiated HDFs. In ROS imaging using confocal microscope we visualized DCF fluorescence in HDFs directly. In conclusion, our results suggest that C.grandiflora can be effectively used for the prevention of UV-induced adverse skin reactions such as radical production, and skin cell damage.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.47 no.3
• /
• pp.185-191
• /
• 2021

Environmental pollution is defined as contamination of the earth's environment with materials which interfere with human health, quality of life, or the natural functioning of the ecosystem. Whenever a prolonged and repetitive exposure to environmental stressors exceeds the skin's normal defensive potential, there is a disturbance in the skin barrier function leading to the development of various skin diseases. Major air pollutants which affect the skin are polycyclic aromatic hydrocarbons, volatile organic compounds, nitrogen oxides, particulate matter, cigarette smoke, heavy metals and arsenic. Dermal uptake depends on the deposition of air pollutants on the skin surface, the composition of epidermal lipids, and the diffusion through the epidermis to the blood vessels.

• ETRI Journal
• /
• v.41 no.1
• /
• pp.84-92
• /
• 2019

Recent advances in digital holography in the far-infrared region of the spectrum have demonstrated the potential use of digital holography in homeland security as a tool to observe hostile environments in which smoke, flames, and dust impair vision. However, to make this application practical, it is necessary to simplify the optical setup. Here, we show an off-axis, self-reference scheme that spills the reference beam out from the object beam itself and avoids the need for a complex interferometric arrangement. We demonstrate that this scheme allows the reconstruction of high-quality holograms of objects captured under visible as well as far-infrared light exposure. This could pave the way to the industrialization of holographic systems to enable users to see through fire. Moreover, the quantitative nature of the holographic signal is preserved. Thus, the reported results demonstrate the possibility to use this setup for optical metrology.

• Journal of Preventive Medicine and Public Health
• /
• v.52 no.2
• /
• pp.92-100
• /
• 2019

Objectives: Young adulthood represents a critical developmental period during which the use of tobacco may begin or cease. Furthermore, differences in smoking behaviors between younger (aged 18-24 years) and older (aged 25-34 years) young adults may exist. This study aimed to characterize patterns related to current smoking in younger and older young adults. Methods: This study used data acquired from the Sixth Korea National Health and Nutrition Examination Survey conducted from 2013 to 2014. A total of 2069 subjects were categorized as younger (712 subjects) and older (1357 subjects) young adults. The chi-square test was used to assess the relationships between smoking status and socio-demographic, health-related, and smoking-related factors. Multivariable logistic regression models were constructed to assess the factors affecting current smoking in these age groups. Results: The current smoking prevalence was 18.3% among the younger young adults and 26.0% among the older young adults. Sex, education level, occupation, perceived health status, alcohol consumption, and electronic cigarette use were related to current smoking in both age groups. Secondhand smoke exposure at home and stress levels showed significant relationships with smoking in younger and older young adults, respectively. Conclusions: Strong correlations were found between the observed variables and smoking behaviors among young adults. Determining the factors affecting smoking and designing interventions based on these factors are essential for smoking cessation in young adults.

• Archives of Craniofacial Surgery
• /
• v.25 no.2
• /
• pp.51-61
• /
• 2024

Background: The influence of smoking on nonsyndromic clefts has been a topic of research for many years. However, few studies have investigated the effect of smoking on causing clefts in different gene pools. Methods: A meta-analysis was conducted of case-control studies related to smoking. Keywords such as "clefts," "cleft lip," "cleft palate," "orofacial cleft," and "smoking" were used to search the MEDLINE, Embase, and Cochrane databases. Results: In total, 51 articles were reviewed. The RevMan software was utilized for the analysis, and the Mantel-Haenszel method was employed to pool the odds ratios (ORs) and 95% confidence intervals. Although the overall OR, a measure of the association between exposure and outcome, was higher for smokers than for non-smokers, this association was significantly stronger in individuals from Asia and South America (1.73), and lowest in Europe (1.31). Among active and passive smokers in Asia, the OR was approximately 0.93, indicating an equivalent impact from both types of smoking. Conclusion: This analysis indirectly suggests that restriction measures targeting both active and passive smoking are crucial in Asia.

• Journal of dental hygiene science
• /
• v.17 no.6
• /
• pp.487-494
• /
• 2017

There is little evidence on the effects of environmental tobacco smoke (ETS) on prevalence of periodontal disease. The aims of this study were to explore the trends of prevalence of periodontal disease and types of exposure to smoke, including ETS according to the survey year, identify factors affecting periodontal disease, and compare the effect size of periodontal disease between active smokers and secondhand smokers. Data on 11,643 individuals were obtained from the fourth and fifth Korean National Health and Nutritional Examination Surveys. Information on exposure to ETS at home and work was self-reported. Severity of periodontal disease was evaluated using the community periodontal index. A multivariate logistic regression analysis was performed to model periodontal disease using types of smoking and the survey year. Overall, the prevalence of periodontal disease was 26.0% (n=3,029) and about 9% of the study population were secondhand smokers. The prevalence of periodontal disease among smokers was significantly increased according to smoking types by year. Active smokers showed a statistically significant adjusted odds ratio (aOR) for having periodontal disease except in the year 2007, whereas secondhand smokers had significant associations only in 2010 (aOR, 1.68; 95% confidence interval, 1.05 to 2.70) compared to non-smokers. For secondhand smokers, the statistical relationship of predicting periodontal disease was weaker than that of active smokers. However, ETS should separately be considered as an important risk factor for periodontal disease. This study suggested the need for further investigation of the impact of ETS on prevalence of periodontal disease using in-depth research designs and objective measurements for assessing periodontal disease and ETS.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.24
• /
• pp.10937-10941
• /
• 2015

Pathogenesis of lung cancer is a complicated biological process including multiple genetic and epigenetic changes. Since cigarette smoking is confirmed as the most main risk factor of non-small cell lung cancer (NSCLC), the aim of this study was to determine whether tobacco exposure plays a role in gene methylation. Methylation of the RAR-${\beta}$ gene were detected using methylation-specific polymerase chain reaction in DNA from 167 newly diagnosed cases with NSCLC and corresponding 105 controls. A significant statistical association was found in the detection rate of the promoter methylation of RAR-${\beta}$ gene between NSCLC and controls ($x^2$=166.01; p<0.01), and hypermethylation of the RAR-${\beta}$ gene was significantly associated with smoking status (p=0.038, p<0.05). No relationship was found between RAR-${\beta}$ gene methylation and pathologic staging including clinical stage, cell type, gender and drinking (p>0.05), and the methylation of RAR-${\beta}$ gene rate of NSCLC was slightly higher in stages III+IV (80.0%) than in I+II (70.8%). Similar results were obtained for methylation of the RAR-${\beta}$ gene between squamous cell carcinoma (77.9%) and other cell type lung cancer (73.9%). These results showed that the frequency of methylation increased gradually with the development of clinical stage in smoking-associated lung cancer patients, and tobacco smoke may be play a potential role in RAR-${\beta}$ gene methylation in the early pathogenesis and process in lung cancer, particularly squamous cell carcinoma. Aberrant promoter methylation is considered to be a promising marker of previous carcinogen exposure and cancer risk.