• BMB Reports
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• 제53권6호
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• pp.311-316
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• 2020

Cholestasis is a condition in which the bile duct becomes narrowed or clogged by a variety of factors and bile acid is not released smoothly. Bile acid-induced liver injury is facilitated by necrotic cell death, neutrophil infiltration, and inflammation. Metformin, the first-line treatment for type 2 diabetes, is known to reduce not only blood glucose but also inflammatory responses. In this study, we investigated the effects of metformin on liver injury caused by cholestasis with bile acid-induced hepatocyte injury. Static bile acid-induced liver injury is thought to be related to endoplasmic reticulum (ER) stress, inflammatory response, and chemokine expression. Metformin treatment reduced liver injury caused by bile acid, and it suppressed ER stress, inflammation, chemokine expression, and neutrophil infiltration. Similar results were obtained in mouse primary hepatocytes exposed to bile acid. Hepatocytes treated with tauroursodeoxycholic acid, an ER stress inhibitor, showed inhibition of ER stress, as well as reduced levels of inflammation and cell death. These results suggest that metformin may protect against liver injury by suppressing ER stress and inflammation and reducing chemokine expression.

• 디지털융복합연구
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• 제10권1호
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• pp.1-10
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• 2012

본 논문에서는 최근 활발히 진화하고 있는 디지털 융합 관련 스마트 어플리케이션을 파악하고 디지털 정책 시사점을 제시하였다. 스마트 어플리케이션에 관한 기존의 많은 연구가 사용자 효용과 기술수용성 등을 중심으로 진행된 반면 정책 관점에 초점을 맞춘 연구는 상대적으로 미흡하였다. 본 연구에서는 이러한 연구의 갭을 메우고자 8개의 핵심 스마트 어플리케이션을 파악하고 이에 대한 삶의 질, 공공 이익, 역작용 등을 체계화하고 델파이 방법론에 기초한 실증분석을 통하여 검증하였다. 8개의 핵심 어플리케이션은 스마트워크와 스마트 상거래로 구분하여 각각 4개의 대표적 어플리케이션을 채택하였다. 본 연구 결과는 향후 관련분야의 디지털 정책 연구에 유용한 기초 결과로 사용될 수 있다.

• 한국정보시스템학회지:정보시스템연구
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• 제31권2호
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• pp.45-62
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• 2022

Purpose Smart farms play a leading role in changing the safety food culture for the citizens. The purpose of this study is to investigate the factors that are important to covid 19-response in the case of ICT smart farm. To do so, we classified the factors as operating effect aspect and industrial wave effect aspect of the smart farm. Design/methodology/approach This study was conducted by visiting Geumsan County, which is attempting to perform a smart farm. Through interviewing farmers representatives based on their operational effect expectations on the smart farm, we derived the industrial crash effect factors and thereafter designed the research model. This study applied AHP, which is an expert decision-making method cans be used to measure relative importance for determining priorities. After interviewing the experts with smart farm, we obtained the factors which are important to smart farm development. Findings According to analysis, the productivity improvement factor was ranked as the most important among the operational effect items. This is consistent with the ultimate goal of smart farms with ICT convergence technology, which is increase the profitability of agriculture. The second place is the factor in the development of infrastructure and infrastructure, and the third and fifth positions were export expansion, environmentally friendly management, and job creation in terms of operational effectiveness.

• 한국방재안전학회논문집
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• 제11권1호
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• pp.15-22
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• 2018

스마트도시란 도시의 경쟁력과 삶의 질 향상을 위하여 건설 정보통신기술 등을 융 복합하여 건설된 도시에 다양한 도시서비스를 제공하는 지속가능한 도시이다. 본 기고에서는 국 내외 스마트도시 추진동향과 지방자치단체의 스마트도시 조직을 분석하여 지속가능한 스마트도시 구현을 위해 지방자치단체의 스마트도시 조직체계 추진방향을 기술하고자 한다.

• 한국산업융합학회 논문집
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• 제21권6호
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• pp.285-299
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• 2018

Recently much attention in building smart factory has been dramatically increased. Despite the growing interest in smart factory, few practical guidelines exist how to successfully build smart factory. The purpose of this study is to postulate and develop a road map for building successful smart factory. To enhance mundane realism, we design the road map through University-Industry research collaboration. Specifically, drawing analysis of University-Industry research collaboration, we design a prototype and detailed road map or building successful smart factory. Moreover, we apply the road map into actual smart factory development. By doing so, we successfully prove the effectiveness of the road map. Therefore, this study provides the valuable guidelines and directions to build a successful smart factory. Ultimately this study is able to help a variety of factories which establish and implement smart factory. Further, we hope that this study will be placed to be an important foundation research on behalf of smart factory building.

• ETRI Journal
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• 제34권6호
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• pp.932-941
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• 2012

A powerful interaction mechanism is one of the key elements for the success of smart TVs, which demand far more complex interactions than traditional TVs. This paper proposes a novel interface based on the famous touch interaction model but utilizes long-range bare hand tracking to emulate touch actions. To satisfy the essential requirements of high accuracy and immediate response, the proposed hand tracking algorithm adopts a fast color-based tracker but with modifications to avoid the problems inherent to those algorithms. By using online modeling and motion information, the sensitivity to the environment can be greatly decreased. Furthermore, several ideas to solve the problems often encountered by users interacting with smart TVs are proposed, resulting in a very robust hand tracking algorithm that works superbly, even for users with sleeveless clothing. In addition, the proposed algorithm runs at a very high speed of 82.73 Hz. The proposed interface is confirmed to comfortably support most touch operations, such as clicks, swipes, and drags, at a distance of three meters, which makes the proposed interface a good candidate for interaction with smart TVs.

• 디지털융복합연구
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• 제12권6호
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• pp.259-264
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• 2014

디지털 컨버전스는 정보통신 영역에서의 단위 기술들의 융합을 통하여 나타나는 새로운 상품이라 할 수 있다. 이러한 컨버전스 시대상황에 맞추어 정부에서는 10개 산업 군을 포함하는 "2025년 ICT 수요조사"를 실시하였다. 본 연구에서는 스마트 시티의 하나의 구성요소인 스마트 모빌리티에 대해 기술하였다. 이러한 스마트 모빌리티의 중심 역할을 수행하는 지능형 교통 시스템은 도로, 차량, 신호시스템 등 기존 교통시스템의 구성요소에 전자, 제어, 통신 등의 첨단기술을 접목시켜 교통시설의 효율을 높이고 안전을 증진하기 위한 교통시스템을 말한다. 본 연구에서는 우리의 일상적인 생활 공간속에서 접하고 있는 지능형 교통시스템에 대한 해외 각국의 사례들에 대해 기술하였다.

• 한국산업보건학회지
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• 제31권4호
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• pp.503-509
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• 2021

Objectives: The utility of the system was analyzed by applying the smart safety technology system to the aging pipe rehabilitation facility construction classified as a confined space. Methods: Smart safety management system was applied to a site where the aging pipe rehabilitation work was in progress. The working environment was measured for 25 days, and the toxic gas saturation was analyzed according to the working time and working place. Results: Based on the measured results, two characteristic environmental changes in the confined space were confirmed. First, when working inside an aging pipe, the tendency of carbon dioxide saturation increases with working time and the number of workers. Second, oxygen decreases when working in a space away from the entrance. Conclusions: Various applications of smart safety technology have been confirmed based on the measured data, and this is expected to be useful for environmental characteristic analysis and safety management when applied to a confined space composed with various conditions in the future.

• International journal of advanced smart convergence
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• 제9권4호
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• pp.173-178
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• 2020

As the fourth industrial revolution, in which people, objects, and information are connected as one, various fields such as smart energy, smart cities, artificial intelligence, the Internet of Things, unmanned cars, and robot industries are becoming the mainstream, drawing attention to big data. Among them, Smart Grid is a technology that maximizes energy efficiency by converging information and communication technologies into the power grid to establish a smart grid that can know electricity usage, supply volume, and power line conditions. Smart meters are equient that monitors and communicates power usage. We start with the goal of building a virtual smart grid and constructing a virtual environment in which real-time data is generated to accommodate large volumes of data that are small in capacity but regularly generated. A major role is given in creating a software/hardware architecture deployment environment suitable for the system for test operations. It is necessary to identify the advantages and disadvantages of the software according to the characteristics of the collected data and select sub-projects suitable for the purpose. The collected data was collected/loaded/processed/analyzed by the Hadoop ecosystem-based big data platform, and used to predict power demand through deep learning.

• 한국IT서비스학회지
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• 제11권2호
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• pp.147-167
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• 2012

In this paper, we attempted to theorize the multi-faceted impacts of smart work on economic activities. In this vein, we adopted socio-economic perspective which includes individual, firm, and social support aspects, and explored the variables related to the quality of life among them. First, smart work patterns are categorized as telework, mobile office, teleconferencing, and social collaboration. And relevant variables are extracted with reference to industrial cases and relevant literatures which investigated economic impacts of digital convergence. Next, with the data collected from experts, following delphi method, validation of variables and explorations of significant factors affecting quality of life were conducted by adopting stepwise regression method. The distinguishing traits of this research are two-folds. The one is the investigation of social support and quality of life aspects of smart work, which has been relatively limited in the digital convergence research field. The other is the comparative analysis of smart work advantages by distinguishing individual and firm aspects separately. The result offers useful insights for socio-economic perspective researches on digital convergence application area.