• Journal of Veterinary Clinics
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• v.36 no.6
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• pp.319-324
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• 2019

Receptor tyrosine kinases (RTK) are major promising targets in anticancer therapy in human and veterinary medicine. Using immunohistochemistry method, we evaluated the expressionof five types RTK (PDGFR-α, PDGFR-β, VEGFR 2, c-Kit and Abl) in the six canine brain tumor samples (2 meningioma, 2 astrocytoma, 1 ependymoma and 1 choroid plexus papilloma). A total of five samples expressed PDGFR-β (5/6), one sample, the choroid plexus papilloma, expressed c-Kit (1/6), and a total of two samples expressed Abl (2/6). None of the samples showed expression of PDGFR-α and VEGFR 2. We demonstrate that a significant portion of canine brain tumors express tyrosine receptors for growth factors and show that these receptors generally localize to tumor cell membranes and the cytoplasm. Evaluation of immunohistochemical expression for the RTKs PDGFR-β, c-Kit, and Alb in canine brain samples reveals an interesting potential for molecular targeting by TKIs in therapeutic studies of canine brain tumors, and more studies will be needed to assess the interactions and efficacy of these RTKs and TKIs. Based on these results, we have some evidence for novel chemotherapeutic trials using TKIs for canine nervous tumors.

• Transactions on Electrical and Electronic Materials
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• v.15 no.5
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• pp.284-289
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• 2014

The effects of additives (Nb, Bi and Cr) on the microstructure, varistor properties, and aging behavior of V/Mn/Co/ La/Dy co-doped zinc oxide ceramics were systematically investigated. An analysis of the microstructure showed that all of the ceramics that were modified with various additives were composed of zinc oxide grain as the main phase, and secondary phases such as $Zn_3(VO_4)_2$, $ZnV_2O_4$, and $DyVO_4$. The $Bi_2O_3$-modified samples exhibited the lowest density, the $Nb_2O_5$-modified sample exhibited the largest average grain size, and the $Cr_2O_3$-modified samples exhibited the highest breakdown field. All additives improved the non-ohmic coefficient (${\alpha}$) by either a small or a large margin, and in particular an $Nb_2O_5$ additive noticeably increased the non-ohmic coefficient to be as large as 36. The $Bi_2O_3$-modified samples exhibited the highest stability with variation rates for the breakdown field and for the non-ohmic coefficient (${\alpha}$) of -1.2% and -26.3%, respectively, after application of a DC accelerated aging stress of 0.85 EB/$85^{\circ}C$/24 h.

• IEMEK Journal of Embedded Systems and Applications
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• v.13 no.1
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• pp.1-8
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• 2018

This paper proposes a low complexity super resolution algorithm for frequency modulated continuous wave (FMCW) radar systems for foreign object debris (FOD) detection. FOD radar has a requirement to detect foreign object in small units in a large area. However, The fast Fourier transform (FFT) method, which is most widely used in FMCW radar, has a disadvantage in that it can not distinguish between adjacent targets. Super resolution algorithms have a significantly higher resolution compared with the detection algorithm based on FFT. However, in the case of the large number of samples, the computational complexity of the super resolution algorithms is drastically high and thus super resolution algorithms are difficult to apply to real time systems. In order to overcome this disadvantage of super resolution algorithm, first, the proposed algorithm coarsely obtains the frequency of the beat signal by employing FFT. Instead of using all the samples of the beat signal, the number of samples is adjusted according to the frequency of the beat signal. By doing so, the proposed algorithm significantly reduces the computational complexity of multiple signal classifier (MUSIC) algorithm. Simulation results show that the proposed method achieves accurate location even though it has considerably lower complexity than the conventional super resolution algorithms.

• Journal of the Korea Institute of Military Science and Technology
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• v.20 no.5
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• pp.654-664
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• 2017

The temperature profiles upon high speed impact of reactive structural materials were analyzed. A two color pyrometer, which included high-speed camera, spectral splitter, and band pass filters, was utilized to measure transient temperature profiles during and after reactive metal samples impacted into steel plate with velocities of 1600~1700 m/s. The spatial temperature distribution was analyzed from the ratio of spectral radiances at two different wavelength in infrared zone, i.e. 700 and 900 nm. The measured temperatures were calibrated with black body source. Two different types of metal samples, namely aluminum and nickel, were employed to understand reaction behavior upon the impact of samples in ambient condition. According to our experiments, the Ni sample appeared to barely react with ambient air producing an instant small fireball, while Al sample reacts violently with air generating a relatively prolong fireball.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.6
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• pp.2709-2729
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• 2016

Representation based classification, kernel method and sparse representation have received much attention in the field of face recognition. In this paper, we proposed an improved kernel principal component analysis method based on sparse representation to improve the accuracy and robustness for face recognition. First, the distances between the test sample and all training samples in kernel space are estimated based on collaborative representation. Second, S training samples with the smallest distances are selected, and Kernel Principal Component Analysis (KPCA) is used to extract the features that are exploited for classification. The proposed method implements the sparse representation under ℓ₂ regularization and performs feature extraction twice to improve the robustness. Also, we investigate the relationship between the accuracy and the sparseness coefficient, the relationship between the accuracy and the dimensionality respectively. The comparative experiments are conducted on the ORL, the GT and the UMIST face database. The experimental results show that the proposed method is more effective and robust than several state-of-the-art methods including Sparse Representation based Classification (SRC), Collaborative Representation based Classification (CRC), KCRC and Two Phase Test samples Sparse Representation (TPTSR).

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2000.11a
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• pp.36-39
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• 2000

A small electrical potential difference which appears on any solid body when subjected to illumination by a modulated light beam generated by laser is called photocharge voltage(PCV)[1,2]. This voltage is proportional to the induced change in the surface electrical charge and is capacitatively measured on various materials such as conductors, semiconductors, ceramics, dielectrics and biological objects. The amplitude of the detected signal depends on the type of material under investigation, and on the surface properties of the sample. In photocharge voltage spectroscopy measurements[3], the sample is illuminated by both a steady state monochromatic bias light and the pulsed laser. The monochromatic light is used to created a variation in the steady state population of trap levels in the surface and space charge region of semiconductor samples which does result in a change in the measured voltage. Using this technique the spatial variation of PCV can be utilized to evalulate the surface conditions of the sample and the variation of the PCV due to the monochromatic bias light are utilized to charactrize the surface states. A qualitative analysis of the proposed measuremen is present along with experimental results performed on amorphous silicon samples. The deposition temperature was varied in order to obtain samples with different structural, optical and electronic properties and measurements are related to the defect density in amorphous thin film.

• Progress in Superconductivity
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• v.9 no.1
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• pp.119-125
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• 2007

We investigated recovery in $Au/YBa_2Cu_3O_7$ (YBCO) thin film meander lines on sapphire substrates. The meander lines were fabricated by patterning YBCO films coated with gold layers. The lines were subjected to simulated AC fault current and then small current was applied for recovery measurements. The samples were immersed in liquid nitrogen during the experiment. After the fault, the resistance decreased linearly, first slowly and then fast to zero. The initial slow decrease was due to the decrease of the meander line temperature, whereas the fast decrease was originated from the transition from the normal state to the superconducting state. The recovery speed depended on the size of samples, and was faster in the smaller samples during the whole period of recovery. The experimental results were analyzed quantitatively with the concept of heat transfer within the sample and to the surrounding liquid nitrogen. A heat balance equation was solved for the initial phase of recovery, and an expression for the time dependence of resistance was obtained. The result agreed with data well.

• Journal of Microbiology and Biotechnology
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• v.20 no.2
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• pp.363-369
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• 2010

This study was conducted to investigate the effects of different sanitizers and contact times on storage quality and microbial growth in fresh-cut broccoli. Fresh broccoli samples were cut into small pieces, washed each for 90 s and 180 s in normal tap water (TW), $100\;{\mu}/l$ chlorinated water (CL, pH 7), electrolyzed water (EW, pH 7.2) containing $100\;{\mu}/l$ free chlorine, or $2\;{\mu}/l$ ozonated water ($O_3$). Then, samples were packaged in 30-${\mu}m$ polyethylene bags and stored at $5^{\circ}C$ for 9 days. No significant differences were observed in gas composition and color parameters ($L^*$, $a^*$, $b^*$, and hue angle) among different sanitizers with contact times. No off-odor was detected during the storage. A longer contact time was not effective in reducing microbial population, except with $O_3$ washing. $O_3$ with 90 s was not much effective in reducing microbial population compared with Cl or EW. However, samples washed with $O_3$ for 180 s observed the lowest numbers of total aerobic and coliform plate counts. The result suggested that, a longer contact time of ozone can be used as a potential sanitizer to maintain the microbial quality and safety of fresh-cut broccoli.

• Journal of Korean Public Health Nursing
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• v.12 no.2
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• pp.136-148
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• 1998

This study was conducted to provide basic knowledge of effective environmental control of patients with allergic rhinitis during the period of July to December 1995. The subjects were consisted of 29 patients with allergic rhinitis. Each patient of nasal symptom scores assessed and dust samples drowned from their bedrooms twice for 1 month interval. The data. 58 samples were analyzed by using ANOVA. t-test and stepwise multiple regression. The results were as follows 1. Out of a total 52 dust samples $(89.7\%)$ were isolated house mites. Total 815mites/0.5gm dust were collected and identified the most prevalent house mites was Pyroglypidae mite with $81.1\%$ 2. The amount of house dust mites in the group of bedding laundry with hot water was significantly lower than that those of with cold water. 3. The nasal symptoms of the patients in the group of bedding laundry with hot water was significantly less than that those of with cold water. and also those of using large size bedroom was significantly lower than that those of using small size one. The nasal symptoms of the patients was closely associated with the washing water temperature. bedroom size. bedroom temperature. type of bedclothes, and frequency of cleanig room.

• Phonetics and Speech Sciences
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• v.7 no.1
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• pp.21-26
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• 2015

The aim of this study is to synthesize pathological breathy voice and to make a cepstral peak prominence (CPP) table following breathiness ranks by cepstral analysis to supplement reliability of the perceptual auditory judgment task. KlattGrid synthesizer included in Praat was used. Synthesis parameters consist of two groups, i.e., constants and variables. Constant parameters are pitch, amplitude, flutter, open phase, oral formant and bandwidth. Variable parameters are breathiness (BR), aspiration amplitude (AH), and spectral tilt (TL). Five hundred sixty samples of synthetic breathy vowel /a/ for male were created. Three raters participated in ranking of the breathiness. 217 were proved to be inadequate samples from perceptual judgment and cepstral analysis. Finally, 343 samples were selected. These CPP values and other related parameters from cepstral analysis are classified under four breathiness ranks (B0~B3). The mean and standard deviation of CPP is $16.10{\pm}1.15$ dB(B0), $13.68{\pm}1.34$ dB(B1), $10.97{\pm}1.41$ dB(B2), and $3.03{\pm}4.07$ dB(B3). The value of CPP decreases toward the severe group of breathiness because there is a lot of noise and a small quantity of harmonics.