• Journal of Korea Foundry Society
• /
• v.35 no.5
• /
• pp.109-113
• /
• 2015

In this study, the measurement of FN (ferrite volume fraction) and the solution annealing ratio at a temperature of $1130^{\circ}C$ were determined with 15A elbow fittings of shell cast SSC13, and the corrosion resistance with and without austenitizing solution annealing were investigated in comparison with AISI304. The delta ferrite phase was observed in the material due to the slow cooling effect of the shell mold casting. However, the delta ferrite phase decreased gradually with the solution annealing at a temperature of $1130^{\circ}C$. The hardness generally decreased with a heat treatment; however, its corrosion resistance was improved with the heat treatment. In addition, when a passivation treatment was applied, its corrosion ratio showed the lowest value. The pattern of general corrosion decreased due to the decrease in the delta ferrite phase with the solution annealing treatment. Consequently, it is suggested that the corrosion resistance of SSC13 elbow fittings can be improved by increasing the ratio of any solution annealing treatment used and by decreasing the ferrite phase. The relationship between the ratio of solution annealing and delta ferrite is expressed as follows: SA (solution annealing ratio,%) = 98 - FN (ferrite volume fraction, %).

• Journal of Digital Convergence
• /
• v.12 no.8
• /
• pp.29-34
• /
• 2014

This study aimed to clarify the relationship which exists between democracy and economic development within Sub-Saharan Africa. It strived to bring out a comprehensive analysis of the reasons why the pace of democratization is slow within this region and why until present date, there are just patches of real democracies there. The work also focuses on the reasons why despite democratic movements, economic growth rates have remained lagging behind average until of recent that, and some few countries have emerged to join the list of fastest growing economies in the world. The study further highlights the unique path of Sub-Saharan Africa democratization process should follow since it does not possess the various factors that favored the democratization processes of most developed countries. In order to obtain the objectives, previous studies and statistical data published by official institutes were analysed by using contents analysis methods. Lastly, it proceeds to explain the important role that democracy plays in inclusive economic growth.

• BMB Reports
• /
• v.50 no.2
• /
• pp.60-70
• /
• 2017

Glaucoma is characterized by a slow and progressive degeneration of the optic nerve, including retinal ganglion cell (RGC) axons in the optic nerve head (ONH), leading to visual impairment. Despite its high prevalence, the biological basis of glaucoma pathogenesis still is not yet fully understood, and the factors contributing to its progression are currently not well characterized. Intraocular pressure (IOP) is the only modifiable risk factor, and reduction of IOP is the standard treatment for glaucoma. However, lowering IOP itself is not always effective for preserving visual function in patients with primary open-angle glaucoma. The second messenger cyclic adenosine 3',5'-monophosphate (cAMP) regulates numerous biological processes in the central nervous system including the retina and the optic nerve. Although recent studies revealed that cAMP generated by adenylyl cyclases (ACs) is important in regulating aqueous humor dynamics in ocular tissues, such as the ciliary body and trabecular meshwork, as well as cell death and growth in the retina and optic nerve, the functional role and significance of cAMP in glaucoma remain to be elucidated. In this review, we will discuss the functional role of cAMP in aqueous humor dynamics and IOP regulation, and review the current medications, which are related to the cAMP signaling pathway, for glaucoma treatment. Also, we will further focus on cAMP signaling in RGC growth and regeneration by soluble AC as well as ONH astrocytes by transmembrane ACs to understand its potential role in the pathogenesis of glaucoma neurodegeneration.

• The Korean Journal of Physiology and Pharmacology
• /
• v.10 no.4
• /
• pp.193-198
• /
• 2006

Many gastrointestinal muscles show electrical oscillation, so-called 'slow wave', originated from interstitial cells of Cajal (ICCs). Thus, a technique to freshly isolate the cells is indispensable to explore the electrophysiological properties of the ICCs. To apply an enzyme solution on the serosal surface for cell isolation, the intestine was inverted and 0.02% trypsin solution and 0.04% collagenase solution were applied to serosal cavity. After the enzyme treatment, mucosal layer was removed and longitudinal muscle layer was gently separated from the rest of tissue. The thin layer was stretched in the recording chamber and mounted on an inverted microscope. Using ${\beta}-escine$, perforated whole cell patch clamp technique was used. Under a microscope, the tissue showed smooth muscle cells and interstitial cells around the myenteric plexus. Under voltage clamp condition, three types of membrane potential were recorded. One group of interstitial cells, which were positive to methylene blue and CD34, showed spontaneous outward current. These cells had bipolar shape and were considered as fibroblast-like cells because of their peculiar shape and arrangement. Another group, positive to c-kit and methylene blue, showed spontaneous inward current. These cells had more rounded shape and processes and were considered as ICCs. The third, positive to c-kit and had granules containing methylene blue, showed quiet membrane potentials under the voltage-clamp mode. These cells appeared to be resident macrophages. Therefore, in the freshly isolated thin tissue preparation, methylene blue could easily identify three types of cells rather than morphological properties. Using this method, we were able to study electrical properties of fibroblast and residential macrophage as well as myenteric ICCs.

• Applied Chemistry for Engineering
• /
• v.7 no.1
• /
• pp.59-66
• /
• 1996

Novel chitosan beads containing a series of bisamino-terminated polyethylene glycol (Bisamino-PEG, $Jeffamine^{(R)}ED$ series) have been prepared via capillary extrusion method using an alkaline solution. The results of swelling kinetics of chitosan beads showed that as the chain length of PEG in chitosan beads increased, the swelling process of the beads proceeded slowly. In order to study the releasing kinetics quantitatively, fluorescamine was coupled to the pendant amino groups and the releasing processes were followed by UV spectra. The results revealed that the releasing process was retarded in the order of $Jeffamine^{(R)}ED$-600 < $Jeffamine^{(R)}ED$-900 < $Jeffamine^{(R)}ED$-2001 as the chain length of PEG was increased. The slow release of PEG from the beads is considered to be governed by the chain length of PEG and interpolymeric hydrogen bonding between PEG and the chitosan molecule.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.25 no.4
• /
• pp.671-682
• /
• 1998

Electrophysiological phenomena of pyramidal cells in the CA1 area of the dorsal hippocampus were recorded from and filled with neurobiotin in anesthetized rats. The electropharmacological properties of membrane as well as the cellular-synaptic generation of rhythmic slow activity (theta) were examined. The intracellular response characteristics of these pyramidal cells were distinctly different from responses of interneurons. Pyramidal cells had a high resting membrane potential, a low input resistance, and a large amplitude action potential. A afterhyperpolarization was followed a single action potential. Most of pyramidal cells did not display a spontaneous firing. Pyramidal cells displayed weak inward rectification and anodal break excitation. The slope of the frequency-current relation was 53.4 Hz/nA for the first interspike interval and 15.9 Hz/nA for the last intervals, suggesting the presence of spike frequency adaptation. Neurobiotin-filled neurons showed pyramidal morphology. Cells were generally bipolar dendritc processes ramifying in stratum lacunosum-moleculare, radiatum, and oriens. Commissural stimulation discharged pyramidal cells, followed by excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs). The frequency of theta-related membrane potential oscillation was voltage-independent in pyramidal neurons. At strong depolarization levels (less than 30 mV) pyramidal cells emitted sodium spike oscillation, phase-locked to theta. The observations provide direct evidence that theta-related rhythmic hyperpolarization of principal cells is brought by the rhythmically discharging interneurons. Furthermore, the findings in which interneurons were also paced by rhythmic inhibitory postsynaptic potentials during theta suggest that they were periodically hyperpolarized by their GABAergic septal afferents.

• Ocean Systems Engineering
• /
• v.4 no.2
• /
• pp.137-150
• /
• 2014

In the marine industry although there has been significant growth towards safety, security and risk assessments or risk-based strategies such as marine insurance and regulations to avoid the risks of damage to properties and the environment or the prospect of premature death caused by accidents etc, the moves toward managing the risks which are linked directly to the business functions and decision making processes have been very slow. Furthermore in the marine industry most perceptions, methodologies and frameworks of dealing with hazards, risks, safety and security issues are for their assessment rather than their management. This trend reveals the fact that in different marine industry sectors such as logistics and shipping there is a lack of coherent risk management framework or methodology from which to understand the risk-based decisions especially for the purpose of design, construction, operation, management and even decommissioning of the marine related applications. On the other hand risk management is not yet viewed holistically in the marine industry in order to, for example, assign a right person, i.e. risk manager, who can act as a coordinator and advisor with responsibilities that are only specific to risk management. As a result this paper, by examining the present physical borders and risk-based activities in the marine industry, aims to propose an appropriate risk management methodology in addition to the emergent role of risk managers which will enable the industry users initially to become familiar with the concept of risk management at its holistic level. In the later stages this eventually can lead to development of risk management capabilities at an exclusive level and its integration into the marine industry functions in future.

• Bulletin of the Korean Chemical Society
• /
• v.32 no.2
• /
• pp.583-589
• /
• 2011

Fluorescence correlation spectroscopy (FCS) is a sophisticated and an accurate analytical technique used to study the diffusion of molecules in a solution at the single-molecule level. FCS is strongly affected by many factors such as the stability of the excitation power, photochemical processes, mismatch between the refractive indices, and variations in the cover glass thickness. We have studied FCS near the surface of a cover glass by using rhodamine 123 as a fluorescent probe and have observed that the surface has a strong influence on the measurements. The temporal autocorrelation of FCS decays with two characteristic times when the confocal detection volume is positioned near the surface of the cover glass. As the position of the detection volume is moved away from the surface, the FCS autocorrelation becomes one-component decaying; the characteristic time of the decay is the same as the faster-decaying component in the FCS autocorrelation near the surface. This observation suggests that the faster component can be attributed to the free diffusion of the probe molecules in the solution, while the slow component has its origin from the interaction between the probe molecules and the surface. We have characterized the surface contribution to the FCS measurements near the surface by changing the position of the detection volume relative to the surface. The influence of the surface on the diffusion of the probe molecules was monitored by changing the chemical properties of the surface. The surface contribution to the temporal autocorrelation of the FCS strongly depends on the chemical nature of the surface. The hydrophobicity of the surface is a major factor determining the surface influence on the free diffusion of the probe molecules near the surface.

• Journal of the Korean Society of Food Culture
• /
• v.12 no.3
• /
• pp.331-339
• /
• 1997

With increases in senior citizens and changes in family structure, the need for long-term care system for elderly is increasing, however, the capacity and environment of Korean facilities are very limited. Health and nutritional status of long-term care residents are worse than free-living elderly. In this study, general food service management and health care practices in long-term care systems were investigated. Questionnaire were sent to the directors of all 162 long-term care facilities in Korea and 81 returned the complete answers. The results showed 1) There are slow but steady increase in long-term care systems in Korea, however, the capacity is far from adequate. Less than 10,000 elderly were resided in the facilities. Most of the systems were free-nursing homes and supported by the goverment. Staffing structure revealed that most of the facilities had a director, a secretary, nurses, but only 21% of the systerm hired a dietitian. It showed the shortage of nurses, physical therapists, and dietitians. Therefore, food purchasing, menu planning, food delivery, and the other food service management processes are handled by non-professionals, such as director, secretary, or cooks. Modified fool frequency questionnaire were used to get the frequencies of each food items used in menu and a menu-analysis was made on the one-day menu provided by the facilities. The results showed relatively satisfactory in nutrients content and food frequencies., however, this was about what was used in menu, not what was eaten by the residents. Therefore this results did not tell that the food intake status of individuals. In most facilities general health checkup was done on a regular basis, and had residents with various chronic degenerative diseases, such as hypertension, neuralgia, stroke, arthritis, diabetes. But the items checked on health checkup included weight, height, blood and urine tests, X-ray test, which suggested that the checkup lists should be revised to accomodate the health problem of the aged today.

• Journal of the Korean Ceramic Society
• /
• v.22 no.5
• /
• pp.9-16
• /
• 1985

Agglomeration of Y-PSZ and its related properties were studied. The ultrafine $ZrO_2$ powder containg 3 mol% $Y_2O_3$ was prepared by 1) coprecipitation method b) hot petroleum drying method c) sol-gel method and the characteristics of calcined powders and the microstructures of sintered body were observed. Powder prepared by the coprecipitation method was about 125$\AA$ in crystallite size and 0.1~1.0${\mu}{\textrm}{m}$ of intra-agglomerate pore size when calcined at $600^{\circ}C$ for 1 hour. because of small crystallite size and weak agglo merate strength resultant densification of sintered body was high. But above the temperature of 130$0^{\circ}C$ efflorescent phenomena due to anions attached to powder surface was observed. Powder prepared by hot petroleum drying method was 65$\AA$ in crystallite size and 1~10${\mu}{\textrm}{m}$ of intraagglome-rate pore size and it was observed that the agglemerates were formed during the calcining process. In this case despite of small crystallite size the rate of sintering was slow and the existing lenticular interagglomerate pore was not eliminated to the final stage of sintering. Powder prepared by sol-gel method showed solid agglomertes due to rapi dhydrolysis reaction. In this powder which involves strong solid agglomerates overall sintering rate was determined by the sintering between the agglomerates and therefore sinterability of powders made by sol-gel method was very poor.