• Journal of Gastric Cancer
• /
• 제15권4호
• /
• pp.238-245
• /
• 2015

Purpose: This study aimed to identify time-dependent prognostic factors and demonstrate the time-dependent effects of important prognostic factors in patients with advanced gastric cancer (AGC). Materials and Methods: We retrospectively evaluated 3,653 patients with AGC who underwent curative standard gastrectomy between 1991 and 2005 at the Korea Cancer Center Hospital. Multivariate survival analysis with Cox proportional hazards regression was used in the analysis. A non-proportionality test based on the Schoenfeld residuals (also known as partial residuals) was performed, and scaled Schoenfeld residuals were plotted over time for each covariate. Results: The multivariate analysis revealed that sex, depth of invasion, metastatic lymph node (LN) ratio, tumor size, and chemotherapy were time-dependent covariates violating the proportional hazards assumption. The prognostic effects (i.e., log of hazard ratio [LHR]) of the time-dependent covariates changed over time during follow-up, and the effects generally diminished with low slope (e.g., depth of invasion and tumor size), with gentle slope (e.g., metastatic LN ratio), or with steep slope (e.g., chemotherapy). Meanwhile, the LHR functions of some covariates (e.g., sex) crossed the zero reference line from positive (i.e., bad prognosis) to negative (i.e., good prognosis). Conclusions: The time-dependent effects of the prognostic factors of AGC are clearly demonstrated in this study. We can suggest that time-dependent effects are not an uncommon phenomenon among prognostic factors of AGC.

• 정보처리학회논문지:소프트웨어 및 데이터공학
• /
• 제7권9호
• /
• pp.345-350
• /
• 2018

본 연구는 지정맥 인식에 중요한 정맥 패턴 특징검출을 위한 알고리즘이다. 특징검출 알고리즘은 패턴인식 시 인식결과에 많은 영향을 끼치므로 중요하다. 인식률은 손가락 위치 변화에 따라 기준도 변화되므로 저하되는 특징을 가지고 있다. 또한, 손가락에 적외선 광을 조사하여 획득한 영상은 영상 배경과 혈관 패턴을 분리하기에 어렵고, 영상 전처리과정을 수행하므로 검출시간이 증대되는 특징을 가지고 있다. 이를 위해, 제시하는 알고리즘은 영상 전처리과정이 없이 수행되어 검출 시간을 줄일 수 있고, 지정맥 영상에 SWDA(Shifted Waveform Data Analysis) 알고리즘을 적용하여 손가락 마디 위치 및 정맥 패턴 검출이 가능한 특징을 가지고 있다. 적외선 투과율이 낮아 상대적으로 어두운 정맥 영상도 검출 오류 최소화가 가능한 특징을 보였다. 또한, 손가락 마디 위치는 분류 단계에서 기준으로 활용하면 인식률 저하를 보완할 수 있는 특징을 가지고 있다. 추후 손바닥, 손목 등 신체 여러 인식분야에 제안하는 알고리즘을 적용한다면 생체 특징 검출 정확도 향상 및 인식 수행 시간 감소에 기여할 것으로 기대된다.

• 한국방재안전학회논문집
• /
• 제17권2호
• /
• pp.1-11
• /
• 2024

국내 저수지의 대부분 흙댐으로 되어있다. 흙댐은 건설비용이 저렴하고, 용이한 시공성을 가지고 있기 때문이다. 그러나 흙댐은 침투나 월류에 매우 취약하기 때문에, 과도한 홍수량이 발생하였을 경우 급격한 붕괴 가능성이 매우 높다. 급격한 붕괴는 급격한 홍수량 증가로 이어져, 하류 하천 또는 민가에 매우 큰 피해를 발생시킬 가능성이 있다. 이에 본 연구에서는 흙댐 사면에 포설한 사석의 흙댐 붕괴 지연효과에 대해 실험연구를 수행하였다. 붕괴시간이 지연되면, 대피시간을 확보하여 인명 피해를 크게 줄일 수 있기 때문에 재난 대응 관점에서 큰 의미가 있다고 판단된다. 수리실험은 직선형 개수로에서 수행하였으며, 보호공 사석의 크기를 2가지로 결정하였다. 기존 선행 실험과는 달리 실험을 부정류로 수행하였으며 이를 통해 댐 내부의 수위 상승 변화 효과를 반영하였다. 대상댐은 도수터널에 설치된 가물막이 댐으로 결정하였다. 실험결과 수행한 실험조건에서 사석보호공이 있는 경우 사면의 붕괴를 방지할 수 있었고, 사석보호공이 없는 경우 사석의 입경 증가에 따라 붕괴 시간 지연 효과가 있는 것으로 나타났다. 이는 첨두 유출량 감소로 댐 하류부의 피해를 감소시키는 효과가 있을 것으로 판단된다. 또한 저수지 붕괴에 대한 비상대처계획(EAP) 수립 시 주요 참고자료로 활용될 수 있을 것이다.

• 전자공학회논문지S
• /
• 제35S권12호
• /
• pp.84-92
• /
• 1998

본 논문에서는 왼쪽 카메라와 오른쪽 카메라에서 획득된 두 영상에서 변이를 찾는 새로운 비용함수를 제안하였다. Cox 등[10]은 극상선상에서 화소의 밝기값으로 비용함수를 계산한 후, 동적 프로그래밍법을 사용하여 스테레오 정합문제를 해결하였다. 본 논문에서는 밝기값 외에 새로운 두 비용함수를 제안하였다. 하나는 화소의 기울기 정보를 밝기값과 방향성의 가중치를 결정하는 기준으로 사용하는 것이다. 기울기가 큰 화소는 주로 화소의 밝기값에 의해 정합이 이루어지고, 기울기가 작은 화소는 방향성을 이용한 정합이 이루어지도록 비용함수를 조절하였다. 다음으로 현재의 극상선상에서 변이를 구하기 위해 이전 극상선에서의 정합이 이루어진 두 화소 $p-k$와 $p-l$가 현 비교되는 화소와 같은 경계선상에 위치하면, $p-i$와 $p-j$가 정합이 이루어질 가능성을 크게 비용함수를 조절하였다. 제안된 방법을 여러 영상에 적용한 결과 이전의 방법보다 더 정확한 정합이 이루어짐을 확인하였다.

• 한국가금학회지
• /
• 제23권4호
• /
• pp.169-175
• /
• 1996

An experiment was conducted with male broiler chicks to determine the effect of different dietary phosphorus sources and evaluate the biological availability of phosphorus sources. The biological availability of phosphorus from dicalcium phosphate (DCP) was used as a reference standard (100%) compared to defluorinate phosphate (DFP). DCP and DFP was supplemented to a corn-soy basal diet at levels of 0.05, 0.15, 0.25, 0.35%. Each of 24 pens of 10 male broiler chicks with three replications was used for three weeks. The results indicated that weight gain, feed in-take, feed efficiency, nonphytic phosphorus (NPP) and tibia ash were significantly different among treatments. Dietary supplemental phosphorus of DFP improved weight gain, NPP intake and feed efficiency consistently, whereas supplements of DCP did not show consistent increase. Regression equations was used for the availability of DPP compared with DCP when percent bone ash was a function of total phosphorus in the diet. The percent (%) bone ash of DFP groups compared to that of DCP groups showed a value of 59.98% as a slope ratio. DFP indicated lower biological availability compared to DCP, but it's dietary supplementation tended to increase bone ash and maximize the growth of young broiler chicks.

• 농촌계획
• /
• 제10권4호
• /
• pp.9-18
• /
• 2004

The purpose or this study is to simulate spatially the urban expansion phenomena with a cellular automata (CA) technique using GIS. A study area, Suwon city, was selected for test of model verification and application with the classified land-use maps of three data years: 1986, 1996, and 2000. The urbanized potential maps were generated with seven criteria of one geographic factor (slope of land), and six accessibility factors (time distances from city, national road, Seoul, station, and built-up boundary), considering their weighting values, which were optimized by WSM (weighted scenario method for intensity order) combined a ranking method and a AHP technique. The optimized weighting values at the urban expansion between 1986 and 1996 were applied to verify the CA model for the other expansion between 1996 and 2000. The results of model application showed that urban sprawl phenomena of the urban expansion toward rural area can be simulated spatially and temporally with several boundary conditions considering various scenarios for the criteria and parameters of the model. Ultimately, this study can contribute to reference data for land-use planning of urban fringe areas.

• 한국환경복원기술학회지
• /
• 제8권2호
• /
• pp.21-32
• /
• 2005

Questionnaire survey from 101 visitors and 77 specialists was carried out to establish the management plan on landscapes of the artificial structure constructed in valley within Bughansan National Park. When comparison was made between ground sill work structure and valley landscape, visitor group responded to the highest scores in valley landscape after planting of vine species in the bottom of the constructure, while specialist group responded to valley landscape after the removal of the constructure. When it made a comparison between revetment work constructure and valley landscape, visitor group responded to highest scores in valley landscape after planting of vine species in the top of the constructure, while specialist group responded to valley landscape after replacing concrete revetment by stone revetment constructure. When it made a comparison between fall work constructure and valley landscape, both groups responded to the highest scores in valley landscape after the removal of the constructure. According to the valley landscape analysis, artificial constructures built in water channel should be matched to adjacent landscape with the removal of concrete constructure. The slope of water channel should be considered to build fall work constructure.

• Genomics & Informatics
• /
• 제19권3호
• /
• pp.34.1-34.6
• /
• 2021

Digital PCR (dPCR) is the third-generation PCR that enables real-time absolute quantification without reference materials. Recently, global diagnosis companies have developed new dPCR equipment. In line with the development, the Lab On An Array (LOAA) dPCR analyzer (Optolane) was launched last year. The LOAA dPCR is a semiconductor chip-based separation PCR type equipment. The LOAA dPCR includes Micro Electro Mechanical System that can be injected by partitioning the target gene into 56 to 20,000 wells. The amount of target gene per wells is digitized to 0 or 1 as the number of well gradually increases to 20,000 wells because its principle follows Poisson distribution, which allows the LOAA dPCR to perform precise absolute quantification. LOAA determined region of interest first prior to dPCR operation. To exclude invalid wells for the quantification, the LOAA dPCR has applied various filtering methods using brightness, slope, baseline, and noise filters. As the coronavirus disease 2019 has now spread around the world, needs for diagnostic equipment of point of care testing (POCT) are increasing. The LOAA dPCR is expected to be suitable for POCT diagnosis due to its compact size and high accuracy. Here, we describe the quantitative principle of the LOAA dPCR and suggest that it can be applied to various fields.

• 한국산업보건학회지
• /
• 제18권3호
• /
• pp.177-184
• /
• 2008

The purpose of this study was to compare the performance characteristics of Andersen and total suspended particulate (TSP) samplers in terms of particle size distribution (PSD) and mass sampling efficiency. In the present study, two Andersen and four TSP samplers were selected and tested to quantitatively estimate human exposure to fly ash representing industrial particulate matter (PM) in a carefully controlled chamber. The PSD characteristics, a mass median aerodynamic diameter and a geometric standard deviation, were found from the sampled PM of airborne samplers in the chamber. An Andersen sampler was compared with a TSP sampler quantified by a coulter counter multisizer, as a reference sampler, to describe the correlation of mass sampling efficiencies between two types of samplers. Overall results indicate that Andersen samplers overestimated small PM due to particle bounce phenomena between impaction stages. There was reasonably good correlation ($R^2$ = 0.89 and 0.91) between the mass sampling efficiencies of Andersen and TSP samplers during the two tests. However, the lower values of slope (0.71 and 0.72) in two tests showed that the Andersen sampler underestimated PM (> AD $10.1\;{\mu}m$) with sufficient inertia due to a relatively lower Andersen inlet velocity at 0.8 m/s comparing with the operating air velocity at 2.1 m/s in the sampling zone of a chamber.

• 한국태양에너지학회 논문집
• /
• 제31권2호
• /
• pp.63-71
• /
• 2011

The remote-sensng campaign was performed at the Pohang Accelerator Laboratory where is located in a basin 6km inland from Yeongil Bay. The campaign aimed uncertainty assessment of Remtech PA0 SODAR through a mutual comparison with WindCube LIDAR, the remote-sensing equipment for wind resource assessment. The joint observation was carried out by changing the setup for measurement heights three times over two months. The LIDAR measurement was assumed as the reference and the uncertainty of SODAR measurement was quantitatively assessed. Compared with LIDAR, the data availability of SODAR was about half. The wind speed measurement was fitted to a slope of 0.94 and $R^2$ of 0.79 to the LIDAR measurement. However, the relative standard deviation was about 17% under 150m above ground level. Therefore, the Remtech PA0 SODAR is judged to be unsuitable for the evaluation of wind resource assessment and wind turbine performance test, which require accuracy of measurement.