• Title/Summary/Keyword: Sleep-Wake

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Repeated Administration of Korea Red Ginseng Extract Increases Non-Rapid Eye Movement Sleep via GABAAergic Systems

  • Lee, Chung-Il;Kim, Chung-Soo;Han, Jin-Yi;Oh, Eun-Hye;Oh, Ki-Wan;Eun, Jae-Soon
    • Journal of Ginseng Research
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    • v.36 no.4
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    • pp.403-410
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    • 2012
  • The current inquiry was conducted to assess the change in sleep architecture after long periods of administration to determine whether ginseng can be used in the therapy of sleeplessness. Following post-surgical recovery, red ginseng extract (RGE, 200 mg/kg) was orally administrated to rats for 9 d. Data were gathered on the 1st, 5th, and 9th day, and an electroencephalogram was recorded 24 h after RGE administration. Polygraphic signs of unobstructed sleep-wake activities were simultaneously recorded with sleep-wake recording electrodes from 11:00 a.m. to 5:00 p.m. for 6 h. Rodents were generally tamed to freely moving polygraphic recording conditions. Although the 1st and 5th day of RGE treatment showed no effect on power densities in nonrapid eye movement (NREM) and rapid eye movement (REM) sleep, the 9th day of RGE administration showed augmented ${\alpha}$-wave (8.0 to 13.0 Hz) power densities in NREM and REM sleep. RGE increased total sleep and NREM sleep. The total percentage of wakefulness was only decreased on the 9th day, and the number of sleep-wake cycles was reduced after the repeated administration of RGE. Thus, the repeated administration of RGE increased NREM sleep in rats. The ${\alpha}$-wave activities in the cortical electroencephalograms were increased in sleep architecture by RGE. Moreover, the levels of both ${\alpha}$- and ${\beta}$-subunits of the ${\gamma}$-aminobutyric acid $(GABA)_A$ receptor were reduced in the hypothalamus of the RGE-treated groups. The level of glutamic acid decarboxylase was over-expressed in the hypothalamus. These results demonstrate that RGE increases NREM sleep via $GABA_A$ergic systems.

Effects of the Participation in the Rehabilitation Horseback Riding Program on Sleep for individuals with Autism Spectrum Disorder (재활승마 프로그램 참여가 자폐성 장애인들의 수면에 미치는 영향)

  • Son, Sungmin;Jeon, Byoungjin
    • 재활복지
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    • v.21 no.4
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    • pp.195-208
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    • 2017
  • This study aimed to investigate the effect of the participation in rehabilitation horseback riding program on the sleep, and to provide the basic data by analyzing the sleep of individuals with autism spectrum disorders. This study subjects consisted of 10 individuals with autism spectrum disorders residing in a residential care facility for the people with intellectual disabilities. They participated in the 12 weeks rehabilitation horseback riding program regularly. To investigate the effects of participating this program on sleep, subjects' sleep time, wake-up time, total sleep time and wake-up frequency during sleep were measured. Descriptive statistics and Friedman test were conducted to analyze the change the sleep. As a reulst of anlysis, it was found that the sleep time came earlier, the total sleep time increased, and the wake-up frequency during sleep reduced. Therefore, the rehabilitation horseback riding program participation was shown to have a positive effect on the subjects' sleep. Since the application of this program can act as a positive factor in the sleep of the participations, it is expected to be used as an in-facility program for the residents with autism spectrum disorders.

Evaluation of Thermal Comfort during Sleeping in Summer - Part I : On Results of Questionnaire Before and After Sleep - (여름철 수면시 온열쾌적감 평가 - 제1보 : 수면 전후 설문에 관하여 -)

  • Kim Dong-Gyu;Kum Jong-Soo
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.17 no.5
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    • pp.404-409
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    • 2005
  • This study is to investigate effects of thermal conditions on sleep. Five female university students participated in the sleep experiment. Three temperature levels (22, 26, and $30^{\circ}C$) were given, and relative humidity was maintained to $50\%$. When as subject arrived in the chamber at 9 o'clock in the evening, questionnaire was given to check physical and psychological conditions. After checking conditions, subjects went to bed till 07 : 30 in the morning. Body movement was checked during sleeping. After sleep in the chamber, questionnaire was given to the subject in order to check sleep quality. Subjects evaluated sleep quality by themselves by answering the time they fall asleep and wake up, frequency of wake during sleep, causes of each waking, and feeling after sleep. Sleep quality was rated with 7-point scale. At $30^{\circ}C$ condition, body movement was significantly higher than of other thermal conditions. The best sleep quality was obtained at the $26^{\circ}C$ condition, while the worst sleep was taken at the $30^{\circ}C$ condition.

The Sleepy Child (졸린 소아에 대한 평가와 치료)

  • Kang, Seung-Gul;Kim, Leen
    • Sleep Medicine and Psychophysiology
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    • v.16 no.2
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    • pp.56-60
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    • 2009
  • Excessive daytime sleepiness in childhood might be abnormal phenomenon and often related to the sleep disorders or insufficient sleep duration. The most common cause of excessive daytime sleepiness would be insufficient sleep. However, narcolepsy, idiopathic hypersomnia, circadian rhythm sleep disorders, medication, medical illness and other sleep disorders that could cause insomnia and poor quality of sleep also result in excessive daytime sleepiness. The misdiagnosed and untreated excessive daytime sleepiness in childhood can lead to serious developmental and educational problem.

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Characteristics of Heart Rate Variability Derived from ECG during the Driver's Wake and Sleep States (운전자 졸음 및 각성 상태 시 ECG신호 처리를 통한 심장박동 신호 특성)

  • Kim, Min Soo;Kim, Yoon Nyun;Heo, Yun Seok
    • Transactions of the Korean Society of Automotive Engineers
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    • v.22 no.3
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    • pp.136-142
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    • 2014
  • Distinct features in heart rate signals during the driver's wake and sleep states could provide an initiative for the development of a safe driving systems such as drowsiness detecting sensor in a smart wheel. We measured ECG from health subjects ($23.5{\pm}2.5$ in age) during the wake and drowsiness states. The proposed method is able to detect R waves and R-R interval calculation in the ECG even when the signal includes in abnormal signals. Heart rate variability(HRV) was investigated for the time domain and frequency domains. The STD HR(0.029), NN50(0.044) and VLF power(0.0018) of the RR interval series of the subjects were significantly different from those of the control group (p < 0.05). In conclusion, there are changes in heart rate from wake to drowsiness that are potentially to be detected. The results in our study could be useful for the development of drowsiness detection sensors for effective real-time monitoring.

The monrningness-eveningness questionnaire in Korean version and Its relations with sleep-wake habits (한국어판 아침-저녁형 질문지 및 수면습관과의 연관성에 대한 연구)

  • ;;松本一彌
    • Journal of the Ergonomics Society of Korea
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    • v.15 no.2
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    • pp.37-49
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    • 1996
  • Morningness-Eveningness Questionnaire (MEQ) of Horne & Ostberg(1976) was translated into a Korean version, and MEQ and life habit inventory was administrated with approximately 900 university students. The distribution of MEQ score was normal. Arising time and bedtine for weekdays and holidays came in the order of morning type, intermediate and evening-type. And the deviation for the evening-type was greatest. Also, the deviation of sleep length for the evening-type was greater than the morning- type. There were tendencies that the bed time and arising time of the male were slightly later than those of the female, and the sleep length of the male was a little longer than that of the female. It also appeared that the arising time was later in the male who completed the military services than those who did not in the chronotype. And the sleep length of the non-served male was longer than that of the served one. Such tendencies noticeably appeared especially the evening-type. The evening-type was subject to heavy variability in bedtime. arising time, and sleep length. The sleep latency of the evening- type was longer and mood on arising was worse. And the ratio of nap or light sleep was higher in these subjects than in others. These results suggested that evening-type students had more irregular and/or flexible sleep-wake habits than the morning-type.

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Effects of Laughter Therapy on Depression and Sleep Wake Disorders of the Elderly in Residential Facilities : A Systematic Review and Meta-analysis (웃음요법이 시설거주 노인의 우울과 수면 장애에 미치는 효과 : 체계적 고찰 및 메타분석)

  • Kim, Eun-Jung;Yang, Jin-Hyang
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.8
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    • pp.291-303
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    • 2021
  • The purpose of this study is to identify the effects of laughter therapy on depression and sleep wake disorders among the elderly in residential facilities using a systemic review and meta-analysis. Twelve databases were searched. Two researchers independently performed the selection of the studies, data coding and assessment. The risk of bias was assessed using risk of bias (RoB) and risk of bias assessment tool for non-randomized studies (RoBANs). To estimate the effect size, meta-analysis of the studies was performed using R version 4.04. Out of the 1,122 retrieved articles, one randomized controlled trial (RCT) and eleven non-randomized controlled trials (non-RCTs) were selected for analysis. The overall effect size of eleven studies on depression was determined to be -1.04 (95% Cl: -1.53~-0.54, p<.001). There were statistically significant in the effect of below ten sessions and the effect of below 400 minutes'and 400 to 1000 minutes'interventions on depression. The overall effect size of five studies on sleep wake disorders was 0.83 (95% Cl: -0.26~1.93, p=.136), which was not statistically significant. There was statistically significant in the effect of below 300 minutes'interventions on sleep wake disorders. Laughter therapy was an effective non-pharmacological intervention to reduce depression among the elderly in residential facilities. The findings also suggest that guidelines for laughter therapy need to be developed considering the number of sessions and a duration of intervention to reduce depression and sleep wake disorders of the elderly in residential facilities.

Influencing Factors on the Nurse's Shiftwork Tolerance (간호사의 교대근무내성 영향요인)

  • Seo, Yeon-ok;Kim, Souk Young
    • Korean Journal of Occupational Health Nursing
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    • v.25 no.4
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    • pp.373-383
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    • 2016
  • Purpose: The purpose of this study was to identify the factors affecting shiftwork tolerance among nurses and provide basic data, ultimately, in formulating a plan for improving their shiftwork tolerance. Methods: The participants were 317 nurses who were working at three general hospitals in Daejeon and Seoul. Data analyzed t-test, ANOVA, correlation analysis, and regression analysis using SPSS 20.0 program. Results: As for the sub-areas of shiftwork tolerance for the respondents, more than a half of nurses working at shifts suffered from insomnia, felt drowsy, complained of chronic fatigue, and were at the anxious and depressed state. Shiftwork tolerance differed by the daily intake of coffee and exercise. Shiftwork tolerance was significantly positively correlated with sleep-wake habits, hardiness, and flexibility and negatively correlated with a languidity. Regression analysis revealed that shiftwork tolerance was affected by age, sleep-wake habits, languidity, flexibility, and hardiness. Conclusion: To put the results, nurses had shiftwork tolerance affected by sleep-wake habits, languidity, and hardiness. It is therefore necessary to make a scheme for allowing nurses to improve hardiness and flexibility and decrease the languidity with the objective of improving their shiftwork tolerance.

Ginseng Extract Regulates the Alterations of Sleep Architecture and EEG Power Spectra in Restraint Stressed Rats

  • Ma, Yuan;Eun, Jae-Soon;Yang, Shulong;Lee, Kwang-Seung;Lee, Eun-Sil;Kim, Chung-Soo;Oh, Ki-Wan
    • Journal of Ginseng Research
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    • v.34 no.1
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    • pp.30-40
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    • 2010
  • The present investigation was conducted to evaluate the regulation of sleep architecture by the red ginseng water extract (RGE) in acutely and chronically restraint stressed rats. Adult rats were fitted with sleep.wake recording electrodes. Following post-surgical recovery, rats were extensively habituated for freely moving polygraphic recording conditions. Polygraphic signs of sleep-wake activities were recorded for 24 h after RGE administration and induction of stress and were analyzed to understand the regulation of sleep architecture. Acute stress decreased wakefulness and increased total sleep, non-rapid eye movement (NREM) sleep, and rapid eye movement (REM) sleep in both the daytime and nighttime recording. RGE shortened the daytime NREM and REM sleep, without changing the wakefulness and total sleep. RGE increased nighttime wakefulness, and decreased total, NREM and REM sleep. Chronic stress increased wakefulness and decreased total sleep in the daytime recording, and increased REM and decreased NREM sleep in both the day and night time recording. RGE ameliorated chronic stress and induced alterations of REM and NREM sleep in the day and night time sleep architecture. Acute and chronic stress could also induce alternations in cortex electroencephalogram (EEG) recording during NREM, REM sleep and wakefulness. These findings suggest that RGE may modulate the sleep behavior in acutely and chronically stressed rats and the ameliorating effect of RGE on the sleep architecture may involve in modulation of $\alpha$-, $\theta$- and $\delta$- wave activities of the cortical EEG.

Sleep Assessment During Shift Work in Korean Firefighters: A Cross-Sectional Study

  • Jeong, Kyoung Sook;Ahn, Yeon-Soon;Jang, Tae-Won;Lim, Gayoung;Kim, Hyung Doo;Cho, Seung-Woo;Sim, Chang-Sun
    • Safety and Health at Work
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    • v.10 no.3
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    • pp.254-259
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    • 2019
  • Background: This cross-sectional study assessed the sleep quality using the ActiGraph and investigated the relationship between the parameters of sleep assessment and the type of shift work in Korean firefighters. Methods: The participants were 359 firefighters: 65 day workers (control group) and 294 shift workers (shift work group: 77 firefighters with 3-day shift, 72 firefighters with 6-day shift, 65 firefighters with 9-day shift, and 80 firefighters with 21-day shift). Sleep assessments were performed using the ActiGraph (wGT3X-BT) for 24 hours during day shift (control and shift work group) and night shift and rest day (shift work group). The participants recorded bed time and sleep hours during the measurement period. Results: Sleep efficiency, total sleep time, and percentage of wake after sleep onset during night work were lower in the shift work group than control group (p < 0.05). Sleep efficiency decreased in night shift and increased in rest day, whereas wake after sleep onset increased in night shift and decreased in rest day (p < 0.05). Among shift work groups, sleep efficiency of 6-day shift was higher in day shift, and sleep efficiency of 21-day shift was lower in night shift than other shift groups (p < 0.05). Conclusion: We found that the sleep quality in night shift of the shift work group was poorer than the control group. As to the type of shift work, sleep quality was good in 6-day shift and poor in 21-day shift. Thus, fast rotating shift such as 6-day shift may be recommended to improve the sleep quality of the firefighters.