• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.1896-1897
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• 2007

Medical equipment of high frequency has been presently applied to various parts of human body and novel treatment effects have been shown by it. Recently there are many cases that high frequency apparatus has been used in dermatology as the interest in beauty has been growing. Especially used in skin, blood volume is increased by keeping surface temperature of skin at around $43^{\circ}C$ and domodex folliculorum are treated by applying high electric field. It is the aspect we consider that increasing blood volume and domodex folliculorum treatment take effect on hair loss. In this study, high frequency electrotherapy apparatus was proposed to be applied to hair loss treatment. For that, human body was experimented with varying output voltage and frequency. The adjustable switching signal for treatment was obtained from 100[kHz] to 1000[kHz] by using DSP. Stable output specific was also obtained by feedback control to protect human body. The best hair growth conditions were the output voltage of 1.2[kV], the frequency of near 300[kHz] and the maximum current of 2[mA]. We apply this high frequency electrotherapy apparatus to two bald men, 46-year-old and 45-year-old. After treatment for a month they had thick and strong hair.

• 한국지반공학회논문집
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• 제29권1호
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• pp.161-170
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• 2013

본 연구에서는 사질토지반의 거동을 상세히 모사할 수 있는 탄소성모델 및 말뚝절편 수치해석을 적용하여 말뚝지름에 따른 사질토지반에 설치된 현장타설말뚝의 주면마찰거동을 분석하였다. 수치해석 결과는 현재 사용되는 설계방법과 비교하여 극한주면마찰력과 t-z거동을 잘 예측하는 것으로 나타났다. 말뚝지름이 감소함에 따라 말뚝-지반 경계면 및 주위지반에 국부적으로 발생되는 체적팽창과 이에 따라 말뚝주면에 발현되는 유효수평응력이 더 크게 발생하기 때문에 극한주면마찰력이 증가하는 것으로 나타났다. 말뚝지름이 감소함에 따라 t-z곡선 기울기의 증가는 말뚝재하에 따라 발생하는 세가지 전단단계(초기, 체적팽창, 및 일정체적 전단단계)가 일찍 발현되기 때문인 것으로 나타났다. 이러한 현장타설말뚝의 말뚝지름에 따른 극한주면마찰력에 대한 영향은 사질토지반의 상대밀도가 증가하고 구속압이 감소할수록 커지는 것으로 나타났다.

• 대한의용생체공학회:의공학회지
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• 제39권1호
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• pp.30-35
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• 2018

Conventional drug delivery methods mainly include subcutaneous injection and oral administration. Subcutaneous injection has the advantages of delivering the correct concentration, but it might cause pain and trauma to patients. Although oral administrations do not accompany pain as the subcutaneous injection, unexpected side effects may occur because they undergo digestion process and it is not easy for many drugs to be exposed to targeted sites with proper concentration. While dissolving microneedles have been extensively studied to overcome the limitations of conventional subcutaneous injection, the effects on microneedle shapes for drug release have not been fully explored. In this study, the characteristics of hyaluronic acid microneedles for cone and quadrangular pyramidal shapes were examined by the size, volume, contact surface area, skin permeability, and dissolution rate. As a result, the cone shapes of hyaluronic acid microneedles had high skin permeability, and the quadrangular pyramid of shapes hyaluronic acid microneedles showed a fast dissolution rate, given by the large contact area on the skin. Based on the results, we could confirm that the shape of a dissolving microneedles can affect skin permeability and the drug delivery rate.

• Archives of Plastic Surgery
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• 제42권5호
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• pp.601-607
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• 2015

Background Autologous or implant-based breast reconstruction after nipple-sparing mastectomy is increasingly preferred worldwide as a breast cancer treatment option. However, postoperative nipple-areola complex (NAC) necrosis is the most significant complication of nipple-sparing mastectomy. The purpose of our study was to identify the risk factors for NAC necrosis, and to describe the use of our skin-banking technique as a solution. Methods We reviewed cases of immediate autologous breast reconstruction after nipple-sparing mastectomy at our institution between June 2005 and January 2014. The patients' data were reviewed and the risk of NAC necrosis was analyzed based on correlations between patient variables and NAC necrosis. Moreover, data pertaining to five high-risk patients who underwent the donor skin-banking procedure were included in the analysis. Results Eighty-five patients underwent immediate autologous breast reconstruction after nipple-sparing mastectomy during the study period. Partial or total NAC necrosis occurred in 36 patients (43.4%). Univariate analysis and binary regression modeling found that body mass index, smoking history, radiation therapy, and mastectomy volume were significantly associated with NAC necrosis. Of the 36 cases of NAC necrosis, 31 were resolved with dressing changes, debridement, or skin grafting. The other five high-risk patients underwent our prophylactic skin-banking technique during breast reconstruction surgery. Conclusions NAC necrosis is common in patients with multiple risk factors. The use of the skin-banking technique in immediate autologous breast reconstruction is an attractive option for high-risk patients. Banked skin can be used in such cases without requiring additional donor tissue, with good results in terms of aesthetic and reconstructive outcomes.

• Archives of Plastic Surgery
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• 제46권4호
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• pp.359-364
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• 2019

Background Few scales are currently available to evaluate changes in hand volume. We aimed to develop a hand grading scale for quantitative assessments of dorsal hand volume with additional consideration of changes in skin texture; to validate and prove the precision and reproducibility of the new scale; and to demonstrate the presence of clinically significant differences between grades on the scale. Methods Five experienced plastic surgeons developed the Hand Volume Rating Scale (HVRS) and rated 91 images. Another five plastic surgeons validated the scale using 50 randomly selected images. Intra- and inter-rater agreement was calculated using the weighted kappa statistic and intraclass correlation coefficients (ICCs). Paired images were also evaluated to verify whether the scale reflected clinical differences. Results The intra-rater agreement was 0.95 (95% confidence interval, 0.922-0.974). The interrater ICCs were excellent (first rating, 0.94; second rating, 0.94). Image pairs that differed by 1, 2, and 3 grades were considered to contain clinically relevant differences in 80%, 100%, and 100% of cases, respectively, while 84% of image pairs of the same grade were found not to show clinically relevant differences. This confirmed that the scale of the HVRS corresponded to clinically relevant distinctions. Conclusions The scale was proven to be precise, reproducible, and reflective of clinical differences.

• 대한두개안면성형외과학회지
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• 제20권1호
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• pp.10-16
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• 2019

Background: Physicians tend to overcorrect when applying the acellular dermal matrix for reconstructive option because of volume decrement problem after absorption comparing with initial volume. However, there are no studies on the exact volume decrement and absorption rate with commercial products in South Korea. To figure out absorption rate of acellular dermal matrix product in South Korea (Megaderm), authors designed this experiment. Methods: Nine mice were used and randomly divided into three groups by the time with sacrificing. The implant (Megaderm) was tailored to fit a cuboid form ($1.0cm{\times}1.0cm$ in length and width and 2.0 mm in thickness). A skin incision was made at anterior chest with blade #15 scalpel with exposing the pectoralis major muscle. As hydrated Megaderm was located upon the pectoralis major muscle, the skin was sutured with Ethilon #5-0. After the surgical procedure, each animal group was sacrificed at 4, 8, and 12 weeks, respectively, for biopsies and histological analysis of the implants. All samples were stained with routine hematoxylin and eosin staining and Masson's trichrome staining and the thickness were measured. A measurements were analyzed using Friedman test. Statistically, the correlation between thicknesses of Megaderm before and after implantation was analyzed. Results: After sacrificing the animal groups at postoperative 4, 8, 12 weeks, the mean tissue thickness values were $2.10{\pm}1.03mm$, $2.17{\pm}0.21mm$, and $2.40{\pm}0.20mm$ (p= 0.368), respectively. The remaining ratios after absorption comparing with after initial hydrated Megaderm were 82.7%, 85.4%, and 94.5%, respectively. In histopathological findings, neovascularization and density of collagenous fiber was increased with time. Conclusion: Author's hypothesis was absorption rate of implant would be increased over time. But in this experiment, there is no statistical significance between mean absorption thickness of implant and the time (p= 0.368). Also it can be affected by graft site, blood supply, and animals that were used in the experiment.

• Geomechanics and Engineering
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• 제31권1호
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• pp.99-112
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• 2022

The present study examines the natural frequencies (NFs) of perfect/imperfect functionally graded sandwich beams (P/IP-FGSBs), which are composed of a porous core constructed of functionally graded materials (FGMs) and a homogenous isotropic metal and ceramic face sheets resting on elastic foundations. To accomplish this, the material properties of the FGSBs are assumed to vary continuously along the thickness direction as a function of the volume fraction of constituents expressed by the modified rule of the mixture, which includes porosity volume fraction represented using four distinct types of porosity distribution models. Additionally, to characterize the reaction of the two-parameter elastic foundation to the Perfect/Imperfect (P/IP) FGSBs, the medium is assumed to be linear, homogeneous, and isotropic, and it is described using the Winkler-Pasternak model. Furthermore, the kinematic relationship of the P/IP-FGSBs resting on the Winkler-Pasternak elastic foundations (WPEFs) is described using trigonometric shear deformation theory (TrSDT), and the equations of motion are constructed using Hamilton's principle. A closed-form solution is developed for the free vibration analysis of P/IP-FGSBs resting on the WPEFs under four distinct boundary conditions (BCs). To validate the new formulation, extensive comparisons with existing data are made. A detailed investigation is carried out for the effects of the foundation coefficients, mode numbers (MNs), porosity volume fraction, power-law index, span to depth ratio, porosity distribution patterns (PDPs), skin core skin thickness ratios (SCSTR), and BCs on the values of the NFs of the P/IP-FGSBs.

• 한국의류학회지
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• 제19권4호
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• pp.684-695
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• 1995

The purpose of this study was to investigate the influence of the mechanical properties on drapability in the peach skin-like finished fabrics. For this study, the samples used were 50 kinds of peach skin-like finished fabrics. The mechanical properties such as tensile, shearing, bending, compressional, surface characteristic values, thickness and weight were measured with a KES-F system and drupe coefficient by drape tester. The relationship between the characteristic values and drape coefficicients of the peach skin-like finished fabrics results were obtained. 1. Peach skin-like finished fabric had $\pm$2o range of shearing, bending, compression, surface. properties, thickness and weight as compared with Japanese women's thin fabrics. The characteristic mixing values were better with the values of WC/T, W/T, etc. as compared with that of japanese women's thin fabrics. Accordingly, the peach skin-like finished fabrics had a little volume, excellent hanging and drapability as compared with japanese women's thin fabrics. 2. The drape coefficient of peach skin-like finished fabric had a high level of correlation between 2HB, G, WC, MIU, WT, MMD, 2HG, RT, W, B etc. of the mechanical properties. The blocked properties that contributed to the drape coefficient of peach skin-like finished fabrics were in the order of the bending> tensile> thickness> weight properties. This drape coefficients(DC) were found by measuring the mechanical properties according to the obtained regress on equate on. DC=99.0179+17.9023 log G -17.0543 log 2HG5+17.2104 log 2HG+35.7685 log 2HB+ 4.6082 log B-30.5906 log T+4.2308 log W 3. The contribution to the drape coefficient of the characteristic mixing values of peach skin-like finished fabric was in the order of > 2HB/W> 2HB/B> B/W The drape coefficients were found by measuring the characteristic mixing values according to the obtained regression equation. 4. The drape coefficients of peach skin-like finished fabrics were influenced by the differences between the bending of warp direction, bending of weft direction, shearing etc which in turn determine the level of hanging. The regression equation was as follows; 5. The drape coefficients of peach skin.like finished fabrics had a highly positive correlation with the node index. It has an negative correlation with number of nodes.

• Journal of the Korean Wood Science and Technology
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• 제40권1호
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• pp.26-37
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• 2012

최근 들어 한옥에 대한 수요과 공급이 계속해서 늘고 있다. 이러한 한옥이 가지고 있는 가장 심각한 문제는 과도한 지붕구조의 무게와 이로 인해 늘어날 수밖에 없는 구조부재의 대형화이다. 따라서 겉으로는 대단면 목재 부재이면서 다량의 목질부를 제거하여 무게의 경량화를 이루고 감소하는 강도적 성질은 부재의 하이브리드화를 통해 보충할 수 있는 실대재 대단면 스킨팀버를 제작하였다. 소나무와 낙엽송 두 수종을 사용하여 실대재 스킨팀버를 제작하였다. 두 수종에 대해 정각형 스킨팀버와 원통형 스킨팀버 각각을 제작하여 휨성능을 평가하였다. 가공기계의 정밀도 부족으로 인해 부재에 과도한 손상이 발생하여 의도한 정도의 강도적 성질을 얻지 못하였다. 하지만 가공기계의 정밀도 향상을 도모하고 추가적인 하이브리드 구조체 제작을 첨가한다면 경량의 대단면 구조부재의 생산이 가능할 것으로 판단된다. 본 연구에서 실제 제작한 낙엽송과 소나무 실대재 스킨팀버에서는 수종간의 휨성능 차이는 나타나지 않아 적절히 혼용 가능한 것으로 나타났다. 낙엽송의 MOR 기준에서만 정각형과 원통형간에 성능 차이가 인정되어 구분하여 사용해야 할 필요가 있고 나머지에 있어서는 차이가 인정되지 않아 혼용이 가능하다고 판단되었다. 본 연구의 목적이 어느 정도의 강도를 지닌 경량의 대단면 구조재 개발에 있으므로 목질계 우드세라믹이나 경량철골 등을 이용한 하이브리드 구조체를 개발한다면 한옥이나 실내인테리어재료 그리고 기둥-보 공법의 재료 등으로 활용 가능할 것이다.

• The Korean Journal of Physiology
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• 제3권1호
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• pp.19-28
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• 1969

Skin temperatures on 10 sites and rectal temperature at every 10 minutes, oxygen consumption at every 20 minutes were measured on 18 male subjects (ages between 14 and 47 years) after exposure to cold air at $15^{\circ}C$ for two hours in a climatic room. Total body fat measured by means of a skinfold method and ratio of body surface area (S) to body volume (V), S/V, were utilized as basis of observations. Surface area was calculated after DuBois equation and body volume was calculated by our original formula. In influencing on the heat loss from the body core to the cold environment, % fat showed inverse relations, whereas, S/V ratio showed direct relations. Thus these two factors acted antagonistically on the body heat loss. Local skin temperatures showed negative correlations with skinfold thickness on the same site, nemaly, on chest, r=-.567; on back, r=-.507; and on upper arm, r=-.353. The other 7 skin sites showed low correlations with % fat. Minimum mean weighted skin temperature (MWST) showed a negative correlation (r=-.443) with % fat, and showed no correlation with S/V ratio. Oxygen consumption in the cold air at $15^{\circ}C$ increased from the first measurement at 20 minutes after exposure and maintained the same increasing trend up to 120 minutes. ${\Delta}T_R$ was greater in tile lean subjects who showed a greater % change in oxygen consumption. The antagonistic actions of % fat and S/V ratio on the heat loss were manifested by observations as follows: minimum rectal temperature was higher In fat subjects (r=.600) and lower in subjects with a greater S/V ratio (=-.582), ${\Delta}T_R$ was smaller in fat subjects (r=-.738) and greater in subjects with a greater S/V ratio (r=.618). Temperature difference between body core and skin surface (minimum rectal temperature minus minimum MWST) showed a positive correlation with % fat (r=.600) and a negative correlation with S/V ratio (r=-.881). Decrease in the mean body temperature and heat debt, respectively, showed negative correlations with % fat and positive correlations with S/V ratio.