• Title/Summary/Keyword: Skin patch

Search Result 174, Processing Time 0.019 seconds

Design and SAR Analysis of Wearable Antenna on Various Parts of Human Body, Using Conventional and Artificial Ground Planes

  • Ali, Usman;Ullah, Sadiq;Khan, Jalal;Shafi, Muhammad;Kamal, Babar;Basir, Abdul;Flint, James A;Seager, Rob D.
    • Journal of Electrical Engineering and Technology
    • /
    • v.12 no.1
    • /
    • pp.317-328
    • /
    • 2017
  • This paper presents design and specific absorption rate analysis of a 2.4 GHz wearable patch antenna on a conventional and electromagnetic bandgap (EBG) ground planes, under normal and bent conditions. Wearable materials are used in the design of the antenna and EBG surfaces. A woven fabric (Zelt) is used as a conductive material and a 3 mm thicker Wash Cotton is used as a substrate. The dielectric constant and tangent loss of the substrate are 1.51 and 0.02 respectively. The volume of the proposed antenna is $113{\times}96.4{\times}3mm^3$. The metamaterial surface is used as a high impedance surface which shields the body from the hazards of electromagnetic radiations to reduce the Specific Absorption Rate (SAR). For on-body analysis a three layer model (containing skin, fats and muscles) of human arm is used. Antenna employing the EBG ground plane gives safe value of SAR (i.e. 1.77W/kg<2W/kg), when worn on human arm. This value is obtained using the safe limit of 2 W/kg, averaged over 10g of tissue, specified by the International Commission of Non Ionization Radiation Protection (ICNIRP). The SAR is reduced by 83.82 % as compare to the conventional antenna (8.16 W/kg>2W/kg). The efficiency of the EBG based antenna is improved from 52 to 74 %, relative to the conventional counterpart. The proposed antenna can be used in wearable electronics and smart clothing.

Reconstruction of Hypopharynx and Cervical Esophagus : Choice of Flap (하인두 및 경부식도 결손의 재건 : 재건술의 선택)

  • Choi Eun-Chang;Lee Sei-Young;Chung Tae-Young;Kim Se-Heon;Kim Young-Ho;Ryu Dae-Hyun;Kim Choong-Bae
    • Korean Journal of Head & Neck Oncology
    • /
    • v.16 no.1
    • /
    • pp.26-32
    • /
    • 2000
  • Background and Objectives: Various flaps are using for reconstruction of hypopharyngeal and esophageal defect. However, complication and indication of each flap are not fully analyzed. Patient and Methods: Records of 52 hypopharyngeal cancer patients who had surgical treatment and 13 other head and neck cancer patients who underwent hypopharyngeal and/or esophageal reconstruction with flap were retrospectively analyzed. Eighty three percent(54 cases) of patients needed reconstruction other than primary pharyngeal closure. Five split thickness skin graft, 1 pectoralis major myocutaneous flap, 20 forearm free flap, 13 jejunal free flap, 15 gastric pull up were used. Result: Flap failure was noted in 2 cases who had subsequent gastric transposition. Wound dehiscence and fistula were most common problem of forearm free flap. Most fistulas were developed in patients with conduit type reconstruction of forearm flap while there wasn't any fistula in patient with patch type reconstruction. Stenosis of lower anastomosis was the frequent problem of jejunal transfer. Gastric pull-up has frequent com-plication of stomal stenosis. All but three patients had reached oral feeding postoperatively. Conclusion: Based on this study, forearm flap is effective in partial hypopharyngeal defect while jejunum is the choice for circumferential defect. Gastric pull-up is for combined esophageal defect.

  • PDF

A Study on 4 Point Bending Strength of Carbon/epoxy Face Sheet and Honeycomb Core Sandwich Composite Structure after Open Hole Damage (카본/에폭시 면재 및 허니컴 코어 샌드위치 복합재 구조의 구멍 손상에 의한 4점 굽힘 강도 연구)

  • Park, Hyunbum
    • Composites Research
    • /
    • v.27 no.2
    • /
    • pp.77-81
    • /
    • 2014
  • In this study, it was performed damage assessment and repair of small scale aircraft adopted on composite. This aircraft adopted the sandwich structure to skin of wing. This study aims to investigate the residual strength of sandwich composites with nomex honeycomb core and carbon fiber face sheets after the open hole damage by the experimental investigation. The 4-point bending tests were used to find the bending strength, and the open hole was applied to introduce the simulated damage on the specimen. The bending strength test results after open hole were compared with the results of no damaged specimen test. In addition, The damaged composite structure was repaired using external patch repair method after removing damaged area. After that, this study presents comparison results of the experimental investigation between the damaged and the repaired specimen. It was found that the bending strength of repaired specimen was recovered up to 95% of undamaged specimen.

Development of Natural Dishwashing Liquid containing the Curcuma Longa L., Morus alba and Ecklonia cava extracts (강황, 상백피 및 감태 추출 혼합물을 첨가한 천연 주방세제 개발)

  • Jung, Ji-Yeon;Kim, Koth-Bong-Woo-Ri;Song, Eu-Jin;Lee, Chung-Jo;Kwak, Ji-Hee;Choi, Moon-Kyoung;Kim, Min-Jee;Ahn, Dong-Hyun
    • Journal of the Korean Applied Science and Technology
    • /
    • v.27 no.2
    • /
    • pp.157-167
    • /
    • 2010
  • This study was conducted to investigate the quality characteristics of the natural dishwashing liquid added with the mixture extracts of Curcuma Longa L. (CL), Morus alba (MA) and Ecklonia cava (EC) at various concentrations. The pH and lightness of the natural dishwashing liquid were reduced by adding the mixture extracts, while the turbidity was increased. The natural dish washing liquid added with mixture extracts was shown to display strong antimicrobial activities against L. monocytogenes compared to that of control. Also, it revealed that antioxidant activity was increased depending on concentrations. However, natural dishwashing liquid added with mixture extracts showed the low detergency efficiency. In sensory evaluation, the natural dishwashing liquid containing CL 0.5%, MA 0.25% and EC 0.25% was preferred than the control and it showed negative result in skin patch test. These results suggest that the addition of CL 0.5%, MA 0.25% and EC 0.25% positively improved the qualities characteristics in the natural dish washing liquid.

Diagnosis of Atopy in Dogs : A Review of the Need for Conceptual and Diagnostic Refinement I (개들의 아토피 진단 : 개념적 및 진단학적 순화의 필요성 검토 I)

  • Perkins Jacqueline
    • Journal of the korean veterinary medical association
    • /
    • v.38 no.4
    • /
    • pp.376-382
    • /
    • 2002
  • 호주의 많은 소동물 임상수의사들이 최근에 관심을 갖고 있는 부분은 개의 아토피(Canine Atopy)에서의 알러지-특이성(Allergen-specific)IgE에 쓰이는 혈청 ELISA (Enzyme-Linked Immuno-Sorbent Assay, 효소결합면역흡착검사)테스트의 활용 가능성에 관한 것이다. 희망사항은 개 아토피의 진단과 치료에 있어서 도움이 되도록 접근할 수 있는 시험(Accessible test)일 것이다. 아토피(Atopy)는 진단과 치료를 실패시키는 질병이며, 새로운 ELISA라도 이 문제를 쉽게 해결하여 주지 못한다. 개의 아토피에서 알려진(Allergens)들을 분석하는 데 쓰이는 혈청 ELISA처럼 아주 정확하게 특성화되어져야 한다. 해당 개는 아토피성(Atopic)으로서 진단되어져야만 되고 그 다음에 치료에 지침이 되도록 개별 알러진 동정(Individual allergen identification)용 ELISA로 개의 혈액을 스크린하는데 적합하여야 한다. ELISA와 피내접종시험(Internal testing)방법은 상관도가 낮고 그렇기 때문에 어떤 시험이 더 신뢰할 수 있는 것일까? 이러한 사실은 논쟁의 여지가 있으며 이상의 2가지 시험들이 옳다면 각각의 상응하는 각각 다른 아형(Subtypes)의 아토피라고 볼 수있다. 아마도 알러진들은 경피적으로 흡수되어 아토피성피부염으로 되어진다. 그것은 인체에서 건초열(Hay fever)이나 천식(Asthma)과 같이 흡입에 의해 일으키는 유사한 증후군동종 (Syndrome akin)과 같은 접근의 초기양식(Primary mode of access)으로부터 생기는 다른 유사한 질병과정이 되어질 수도 있다. 이러한 2가지 증후군은 함께 병발하는 경우가 있다. 의학에서는 피부 반점시험방법의 예비조사연구(Preliminary research with skin patch testing in medicine)는 아토피성 피부염을 야기하는 알러진들의 경피흡수경로의 개념을 지지해준다. 흡인 알러진들을 사용한 개들에서의 도전 시험(Challenge tests)들은 거의 대부분이 비-피부학적 임상증상들을 발현하였다. 모든 증거가 분명히 나타나도록 미래의 조사연구를 인도해 주는 게 필요하며 개 아토피의 정의와 진단을 둘러싼 수수께끼를 해결하는데 도움이 될 것이다.

  • PDF

Multiple Large Cysts Arising from Nevus Comedonicus

  • Jeong, Hii-Sun;Lee, Hye-Kyung;Lee, Seung-Hyun;Kim, Hyoung-Suk;Yi, Sang-Yeop
    • Archives of Plastic Surgery
    • /
    • v.39 no.1
    • /
    • pp.63-66
    • /
    • 2012
  • Nevus comedonicus is a type of hamartoma that arises from a developmental anomaly of the mesodermal part of the pilosebaceous gland. In most cases of nevus comedonicus, an acne-like skin condition develops. Repeated inflammation can cause a morphological change to the cyst, papule, to abscess. We experienced a case of congenital nevus comedonicus, which led to the formation of large multiple cysts. A 50-year-old man was referred with a $12.5{\times}10cm$ lobulated mass on the posterior neck and upper back. The patient had a widespread presence of nevus comedonicus in the region ranging from the right superior chest to the posterior neck. The patient had a 30-year history of six prior excisions. A magnetic resonance imaging review led to a diagnosis of nevus comedonicus. Surgical treatment consisted of excision of the mass and wide excision for the patch type of nevus comedonicus around the neck. On histopathology, multiple masses were diagnosed as typical cysts containing keratinized tissue. The diffuse comedone lesions were diagnosed as nevus comedonicus. This case shows that large, multiple cysts can occur as a long-term complication of nevus comedonicus, and also highlights the importance of radical resection to prevent its further invagination.

A Study on the Decadent Characteristics in Modern Fashion and Make-up (현대 패션 및 메이크업에 표현된 데카당스적 특성에 관한 연구)

  • 선정희;유태순
    • Journal of the Korean Society of Costume
    • /
    • v.51 no.7
    • /
    • pp.63-73
    • /
    • 2001
  • The purpose of this study was to be of use for more successful prediction of possible Prevailing aesthetic characteristics in the future, by reviewing how decadent features have actually been unfolded in fashion and make-up since the end of 20th century, as we are now in the new 21st century. The decadent traits of modern fashion and make-up since the late'90s could be listed as follows : first, the fashion has intentionally been designed to look disgusting, where realistic and imaginary images coexist, by using a half-man, half-machine image or vividly describing detestable animal skin, There have also been disgusting features in the make-up, which are so extremely weird that we can created by adding vinyl or pieces of textiles like Patch of the 17th century. Second, the satanic character of the fashion seems to be meant to keep in harmony with evil image such as Dracula, witch, skeleton or warrior of the evil, in order to charge the unnatural, inhuman and fin-de-siecle Phenomenon and find out what It really means for the inner world of men. And the demonic expressions of the make-up chiefly use white or black color or blue color of low saturation or low lightness, and part of facial features is exaggerated or shortchanged. Third, the decadent characteristics are expressed in the fashion by attaching sensational ornament to the human bode or using sexual exposure. So they give unnatural, unsound and extremely erotic impressions. The decadent features in the make-up are generated by excessively using a gay red color or sensational, exciting colors. Fourth, the exoticism of the fashion is largely affected by China's Chipaoh, Japan's Kimono or primitive motives from Africa, as there are increasing interests in Asia. And that of the make-up leans toward the East, as Kabuki make-up from Japan, Kyongkeuk make-up from China or the primitive features from Africa are employed.

  • PDF

Study on Cosmeceutical Activity of four Kinds of Korea Herb Medicine Materials (4가지 한방 소재(행인, 호장근, 자초, 강황)의 화장품약리활성에 관한 연구)

  • Kim, Youngh-Hun;Lee, Su-Mi;Cheon, Soon-Ju;Jang, Min-Jung;Jun, Dong-Ha;Choi, Hyang-Ja;Cho, Woo-A;Lee, Jin-Tae
    • Journal of the Korean Society of Fashion and Beauty
    • /
    • v.5 no.4
    • /
    • pp.130-138
    • /
    • 2007
  • The aim of this study was to assess the cosmeceutical activies of four kinds of Korea herb medicine extracts using in cosmetics and related industries. The cosmeceutical activities of extracts were investigated by tyrosinase inhibition, astringent, anti-bacterial and MTT assay for cell viability. In the whitening effect, PA that the highest tyrosinase inhibition activity showed 56% at 10 ppm in ethanol extract. Also water and ethanol extract of RE showed 54%, 68% at 1,000 ppm, respectively, but LE and CA showed lower effect. Astringent effect of water and ethanol extract of PA appeared over 60% at 1,000ppm concentration but other extracts showed no astringent effect. In the anti-bacterial test, water and ethanol extract of PA showed no anti-bacterial effect against all microorganisms. But water and ethanol extract of RE showed anti-bacterial effect on Staphylococcus aureus, ethanol extract of showed on Staphylococcus aureus and Propionibacterium acnes, ethanol extract of CA showed on Candida albicans. The resUlt of stability test showed that the emulsion of containing PA were very stable at various temperature and sun-light test. Viscosity and pH of emulsion did not change. From the results of human patch test to assess the safety of cosmetics containing PA there was no negative reaction on skin was found.

  • PDF

Study on the Usage of Acne Patches in Patients with Acne (여드름 환자에서 여드름 패치 사용에 관한 연구)

  • Jung, Hye Jung;Jang, Dong Hyuk;Lee, Jae In;Bae, Joo Youn;Ahn, Ji Young;Park, Mi Youn
    • Korean journal of dermatology
    • /
    • v.56 no.9
    • /
    • pp.539-542
    • /
    • 2018
  • Background: Patients with acne are at risk of using various over-the-counter drugs (OTCs). In addition, several OTCs are introduced in pharmacies in Korea. However, only few drugs are supported by well-established data. Among the treatments, acne patches are easy to purchase and use. Thus, they are widely used by patients. Objective: This study aimed to investigate the patient's perception and usage of acne patches. Methods: A questionnaire survey was conducted on 80 patients with acne who visited the outpatient department of the National Medical Center for 2 months. Results: A total of 42 (52.5%) patients answered that they had used acne patches, and 38 (47.5%) patients stated that they had never used patches. Moreover, 27 (64.29%) patients responded that they used the patches on inflammatory lesions. Moreover, several patients were using acne patches after pricking themselves. There was only one response to confirm the ingredient when purchasing acne patch. Moreover, 14 (33.33%) participants responded that they noted side effects after using acne patches. Overall, the satisfaction score for the use of acne patches was 5.05. Conclusion: Patients often use acne patches because they can be easily purchased and used. However, they do not know how to properly choose and use the product that fits their skin. Therefore, doctors must educate patients on how to properly select and use the products.

A Sensitive, Efficient, and Cost-Effective Method to Determine Rotigotine in Rat Plasma Using Liquid-Liquid Extraction (LLE) and LC-MRM

  • Kim, Ji Seong;Jang, Yong Jin;Kim, Jin Hee;Kim, Jin Hwan;Seo, Jae Hee;Park, Il-Ho;Kang, Myung Joo;Choi, Yong Seok
    • Mass Spectrometry Letters
    • /
    • v.13 no.4
    • /
    • pp.146-151
    • /
    • 2022
  • Rotigotine (RTG) is a non-ergot dopamine agonist used to manage the early stage of Parkinson's disease (PD) as transdermal patch. However, the poor medication compliance of PD patients and skin issues related with repeated applications of RTG patches lead to the search for alternative formulations and it also requires appropriate analytical methods for their in vivo evaluation. Thus, here, a sensitive, efficient, and cost-effective method to determine RTG in rat plasma using liquid-liquid extraction (LLE) and multiple reaction monitoring was developed. The use of 20 µL of rat plasma for sample treatment, 8-OH-DPAT as the internal standard, and methyl tert-butyl ether as the LLE solvent in the present method gives it advantages over previous methods for the analysis of RTG in biological samples. The good analytical performance of the developed method was confirmed in specificity, linearity (the coefficient of determination ≥0.999 within 0.1-100 ng/mL), sensitivity (the lower limit of quantitation at 0.1 ng/mL), accuracy (81.00-115.05%), precision (≤10.75%), and recovery (81.00-104.48%) by following the FDA guidelines. Finally, the applicability test of the validated method to the in vivo evaluation of a RTG formulation showed that the present method is the only method which can be accurately applied to that longer than 24 hours, critical for the development of formulations with reduced dosing frequencies. Therefore, the present method could contribute to the development of new RTG formulations helpful to people suffering from PD.