• 한국응용과학기술학회지
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• 제33권1호
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• pp.30-40
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• 2016

본 연구는 2단계 발효된 달팽이 추출물을 5% 사용한 시트 마스크 팩 (2F-SEM)을 개발하였다. 이에 대한 피부미용학적 연구를 수행하기 위하여 순면 100%의 시트를 사용하여 얼굴모양으로 커팅하여 사용하였다. 플라세보 마스크 팩 (placebo mask pack; PM)과 일반 용매추출에 의한 달팽이 추출물을 사용한 마스크 팩 (Gene-SEM)에 대하여 피부 개선효과를 측정한 결과를 보고한다. 첫째; 2F-SEM의 보습효과는 PM 보다 11%, Gene-SEM는 PM 보다 4.7%가 상승되었다. 둘째; 2차 발효달팽이 추출물이 함유된 마스크 팩의 탄력도는 PM 보다 13.8%, Gene-SEM PM 보다 6.7% 이상 개선하는 효과를 보였다. 셋째; 2F-SEM의 피부 거칠기는 PM 보다 6.80%, Gene-SEM는 PM 보다 2.3%가 개선되었다. 넷째; 2F-SEM의 멜라닌감소효과는 PM 보다 15.0%, Gene-SEM는 PM 보다 8.7%이상 개선되었다. 다섯째; 2F-SEM의 잔주름개선효과는 PM보다 8.0%정도 우수하였다. Gene-SEM는 PM 보다 5.1%이상 개선되었다. 여섯째; 2차 발효 물을 이용한 2F-SEM의 관능 평가는 부드러움(softness), 보습 감(moisture), 주름개선효과(fine wrinkle improvement)에서 유의 차 있는 사용감촉을 보였다.

• 한국식품과학회지
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• 제28권3호
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• pp.470-474
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• 1996

The dielectric properties, dielectric constant (${\varepsilon}‘$) and loss factor (${\varepsilon}’$), of skin and pulp of fresh ginseng were measured from $25^{\circ}C$ to $67^{\circ}C$ using an open-ended coaxial probe technique for 915 MHz and 2450 MHz. Pulp and skin had dielectric constant of $30{\sim}64$ and loss factor between 10 and 20, each variable having a respective frequency dependence typical of materials with high water content. Although the loss factor was nearly constant, the dielectric constant increased as moisture content increased. The dielectric constant of ginseng pulp increased as temperature increased (temperature ${\leq}56^{\circ}C$), but any significant differences were not found in skin dielectric properties. Penetration depth for fresh ginseng were about 2 cm at 91.5 MHz and 1cm at 2450 MHz.

• Preventive Nutrition and Food Science
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• 제11권1호
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• pp.61-66
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• 2006

The objective of this study was to compare the color and microstructure of powder, redness, brownness, and antioxidative activity in extruded ginseng, white ginseng and red ginseng extracts. The colors of extruded dry ginseng powder (moisture content 30%, barrel temperature $110^{\circ}C$, and screw speed 200 rpm) were similar to those of red ginseng. Intact cell wall structure was examined in dried root ginseng at $70^{\circ}C$ (A), white ginseng with skin (D), white ginseng without skin (E), and red ginseng (F) under a scanning electron microscope. The cell wall was not detected in samples B and C (dry ginsengs extruded with 25% and 30% moisture contents, respectively). Intact starch granules were detected in samples A, D, and E under a scanning electron microscope. Melted starch granules were detected in samples B, C, and F. Colors (L, a, b) of 50% EtOH extracts were similar in samples C and F. Browniness and redness of extracts were high in extruded dry ginseng and red ginseng extracts. Extruded dry ginseng (B) showed higher electron donation ability and phenolic content than the other samples.

• 한방안이비인후피부과학회지
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• 제23권3호
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• pp.154-164
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• 2010

Objective : The purpose of this clinical research was to investigate the effects of herbal cosmetics containing Phellinus linteus extracts on patients with atopic dermatitis. Methods : A total of 35 patients who visited Daegu Hanny Oriental Medical Center from November 4th, 2008 to December 28th, 2008 were included in this study. In this study, we observed transepidermal water loss, skin moisture content, modified scorad index of atopic dermatitis and pruritic degree. Statistical analysis was performed by using paired t-test and wilcoxon signed ranks test. Statistical significance was achieved if the probability was less than 5%(p<0.05). Results : Statistically, herbal cosmetics containing Phellinus linteus extracts showed siginificant effect on transepidermal water loss, skin moisture content, modified scorad index of atopic dermatitis and pruritic degree(p<0.05). And satisfaction after using herbal cosmetics was near good. Conclusions : Considering the above results, we have concluded that herbal cosmetics containing Phellinus linteus extracts have the remarkable effects on atopic dermatitis.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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• pp.149-162
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• 2003

Moisturizing the skin is one of the most important functions of skincare cosmetics, because water plays a significant role in keeping the skin healthy. There are various humectants including polyol (glycerin and 1,3-butylene glycol), water-soluble polymers, and botanical extracts. It is well known that the increased amount of polyol in lotion for obtaining high moisturizing effect gives a sticky feeling to the skin. Therefore, a few humectants that can give high moisturizing effect without a sticky feeling for lotion formula is available. On the other hand, oil-based lipstick is well known to have a difficulty to contain a large amount of hydrophilic humectants, because the humectants is unable to be mixed well into oil-based lipsticks and give the lips a peculiar taste. There are newly developed humectants, polyoxyethylene/polyoxypropylene dimethyl ether (EPDME) that can solve these problems describable above. EPDME is a random copolymer of ethylene oxide and propylene oxide. EPDME gives a low sticky feeling with a high moisturizing effect when it is used in lotion. As a remarkable character, EPDME can show not only a preventing effect on rough and dry skin, but also a improving effect upon the use for 1-4 weeks. EPDME can show a synergistic effect with glycerin on preventing to rough and dry skin. Since EPDME can be dissolved in oil-based formulation and used as an ingredient of lipsticks, EPDME can give a moisturizing effect that allows lip to be healthy condition. EPDME can also give no peculiar taste even upon the use of a large amount. EPDME is a useful cosmetic ingredient that can show a good skin care effect in both water-based formula and oil-based formula. EPDME of which polarity can be controllable is expected to be used for various cosmetic applications in near future.

• 한국가금학회지
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• 제43권2호
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• pp.105-109
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• 2016

본 연구는 닭고기 스킨의 첨가가 닭고기 너겟의 품질 특성에 미치는 영향을 조사하였다. 처리구별로 닭고기 스킨을 0%(control), 5%, 10%, 15%를 첨가하여 제조하였다. 수분함량은 닭고기 스킨의 첨가량이 증가할수록 유의적으로 감소하였으나(P<0.05), 지방함량은 닭고기 스킨의 첨가량이 증가할수록 유의적으로 증가하였다(P<0.05). 단백질함량은 닭고기 스킨의 첨가량이 증가할수록 감소하는 경향을 보였다. 회분함량은 닭고기 스킨의 첨가량이 증가할수록 증가하였으나, 대조구와 처리구 간에 유의적 차이는 발견하지 못하였다. 명도는 닭고기 스킨을 첨가함에 따라 유의적으로 증가하는 경향을 보였으나(P<0.05), 적색도와 황색도는 닭고기 스킨의 첨가량이 증가할수록 감소하는 경향을 보였다. 튀김수율은 닭고기 스킨의 첨가량이 증가할수록 감소하는 경향을 보이며, 경도(hardness), 검성(gumminess)과 씹힘성(chewiness)은 닭고기 스킨의 첨가량이 증가함에 따라 감소하는 경향을 보였다. 관능평가에서 다즙성(juiciness)과 전체적인 맛(overall acceptability)은 닭고기 스킨의 첨가량이 증가할수록 증가하는 추세를 보였다. 이러한 결과로 보아 닭고기 너겟에 닭고기 스킨을 첨가 시 품질 특성을 증진시키는 것으로 나타났으며, 관능평가를 기초로 하여 물성 및 튀김수율을 고려하였을 때 약 10%의 닭고기 스킨 첨가가 닭고기 너겟의 적정 첨가비율이라고 판단된다.

• 한국응용과학기술학회지
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• 제36권1호
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• pp.299-304
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• 2019

본 연구는 피부표면온도가 유효물질 경피 흡수와 피부 상태변화에 미치는 영향을 실험하였다. 열에 강한 나이아신아마이드 10% 에멀젼을 인공피부에 도포하여 경피 흡수 시험을 진행하였고 동일한 에멀젼으로 피부임상시험을 시행하여 온열효과를 확인하였다. 그 결과 피부표면 온도 $42^{\circ}C$에서 정상 피부 온도보다 도포 10분 경과 후 2배, 15분 경과 후 3배의 경피 흡수 효과를 보였다. 피부임상평가에서는 임상대상자 모두 특이한 이상반응을 보이지 않았으며 수분, 유분 항목에서 통계적으로 유의한 효과를 나타냈다. 이상의 결과로 온열은 유효물질 경피 흡수 촉진과 피부상태 개선에 긍정적인 영향을 미치는 것을 확인하였고 이는 온열을 이용한 다양한 뷰티디바이스 개발에 기초자료가 될 것으로 판단된다.

• 한국약용작물학회지
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• 제27권2호
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• pp.143-150
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• 2019

Background: Skin is an organ that protects the human body from various environmental stimuli that can induce immune system activation. Skin aging can be largely divided into two categories: physiological aging, which is caused by the a decreased physiological function of the skin and structural changes with aging, and photoaging, which is caused by the chemical stress induced by external stimuli such as ultraviolet (UV) radiation. Methods and Results: The objective of this study was to investigate the anti-wrinkle and UV protective effect of catechin-rich green tea extract (CGTE) in activated keratinocyte (HaCaT cells) and UV-induced skin damage in hairless mice. The results showed that CGTE inhibits the tumor necrosis factor-alpha interferon-gamma ($TNF-{\alpha}+IFN-{\gamma}$)-induced expression of matrix metalloproteinase (MMP)-1 in HaCaT cells. In addition, the CGTE treatment significantly reduced wrinkle formation, epidermal thickness, collagen deposition, and transepidermal water loss in dorsal skin irradiated with UVB. However, the ${\beta}$-glucosidase activity was significantly increased. The CGTE treatment inhibits mRNA expression and enzyme activity of MMP-2 and MMP-9 in the dorsal skin irradiated with UVB. Conclusions: It is expected that CGTE can be effectively used as a functional food and cosmetic ingredient to improve skin moisture retention and reduce wrinkle formation.

• 한국산학기술학회논문지
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• 제14권1호
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• pp.239-246
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• 2013

본 연구는 모시대(Adenophora remotrflora)잎을 이용하여 항산화 활성 및 중년여성을 대상으로 피부 개선 효과를 측정함으로써 화장품 소재로서의 가능성을 알아보고자 하였다. 모시대잎의 항산화 활성 측정결과 모시대잎 열수추출물의 DPPH 소거능이 에탄올추출물에 비하여 약 9% 정도 높은 값을 보였고(p<0.05), hydroxyl radical 소거능의 경우에는 열수추출물(65.22%)이 에탄올추출물(63.50%)에 비해서 약간 높았지만 유의적인 차이는 나타나지 않았다. 총 폴리페놀화합물 함량의 경우에는 에탄올추출물(47.90 mg/mL)이 열수추출물(40.82 mg/mL)에 비해 유의차 있는 효능을 보였다(p<0.05). 2011년 10월 20부터 11월 17일까지 35~60세 중년여성 16명을 대상으로 오른쪽 얼굴에는 베이스팩을, 왼쪽 얼굴에는 모시대잎 파우더팩을 주 2회씩 4주 동안 적용하여 수분, 거칠기, 모공, 투명도를 측정한 결과 수분함량, 색소침착에서 유의한 변화가 나타났으나(p<0.05) 거칠기, 모공크기에서는 유의한 차이는 없었지만 개선 효과가 있음을 확인할 수 있었다. 따라서 모시대잎은 새로운 화장품소재로서 피부개선 효과가 있음을 확인하였다.

• 혜화의학회지
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• 제21권1호
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• pp.1-9
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• 2012

Objectives : The aim of this experiment is to find out relationship between the effect of cosmetics and 4 types of pattern identification about fluid-humor, which are based on the general idea of traditional oriental medicine, Qi-Blood and deficiency-excess. Methods : Korean female volunteers in good health (n=25, $23.12{\pm}2.83$) participated in this experiment. Three Korean medical doctors classified them into 4 groups: Blood-deficiency: group A; Blood-excess: group B; Qi-deficiency:group C; Qi-excess:group D). Cosmetics that contains herb extract for Blood deficiency were given to all volunteers and they used the cosmetics for 4 weeks. Volunteers were assessed non-invasively with the skin measuring devices before and after using cosmetics. And we analyzed the correlation of skin physiological parameters with 4 groups. Results : Three doctors diagnosed participants and classified them into 4 groups ; group A(n=8),group B(n=7), group C(n=3), group D(n=5) as highest score. After 4 weeks, facial skin moisture showed no significant difference in comparison between 4 groups. Sebum showed significant increase in Group A and significantly decreased Group B. Measurement of facial skin elasticity tended to increase in Group A, C, D but skin elasticity was decreased significantly in Group B. Conclusions : In case of a group that pattern identification about fluid-humor corresponds to herb extract in cosmetic, skin improving effect was better than the other group that pattern identification oppose to properties of herb in cosmetic. Therefore, from the view of traditional oriental medicine, it is very important to understand user's pattern of identification or physical conditions and properties of herbs in cosmetics on the matter of safety and efficacy.