• 동의생리병리학회지
• /
• 제22권4호
• /
• pp.930-942
• /
• 2008

Following conclusions were derived from researching various consumption caused after surgical operation. The meaning of surgery in HyungSang medical point of view is a big flaw of the original configuration. Therefore meaning, the loss of container to store something. Changes of the body after surgery can be formation of stagnated blood and abnormal cyst of the removed part and entangled undigested food and stagnant blood. After surgery when the symptoms become chronic or the patients develop side effects as they age, consumption and aging process begins. HyungSang medical treatments of consumption caused after surgery are the followings. We should prevent aging of the framework by using appropriate medication to make up for faults in Gall Bladder, Bladder type and six meridian type by considering its form, color, pulse and symptoms. Stability of emotion that can endure various mental stimulation is needed. Prevent stagnation, indigestion, obstruction and numbness by smoothing up the constructive energy and the defensive energy in the operated part. The Heart and Kidney should be under control and Stomach and Spleen should be reinforced so that food intake is accelerated and produce vital substances and Ki and blood. Eum blood and Yang Ki should circulate around the body well. Examine daily life and if small changes in skin complexion, appetite, sleep and excretion occur, also difference in adaptation of external stimulation and mental health occurs immediate treatment and care is necessary. Treatment of side-effects caused from both aging process and post-surgery in HyungSang's view point is considered better than other ways of treatment and will contribute in expanding the field of medical science.

• 지역사회간호학회지
• /
• 제14권2호
• /
• pp.274-286
• /
• 2003

Purpose: The purpose of this study is to provide a basic data that may help develop health promotion programs by identifying health problems and perceived health status of the rural elderly. Method: The subjects of the study were 366 elders recruited from 24 villages located in Mari Myun, Geochang Gun, Korea. The sample was selected using a quota sampling method. The instruments used in the study included 117 items for health problems and 4 items for perceived health status. The data were analyzed with descriptive statistics, Pearson correlation coefficient, t-test, ANOVA and scheffe test using SPSS program. Results: 1) The most prevalent health problem was ailments in 'musculoskeletal system', followed by 'fatigue', 'eyes and ears', 'genitourinary system', 'mood & temper patterns', 'cardiovascular system', 'digestive system', 'nervous system', 'respiratory system' and 'skin'. 2) Womens health problems were more prevalent than men's health problems. 3) The mean score of perceived health status was 7.68. 4) Health problems of the rural elderly were significantly correlated with demographic variables such as education (F=9.532, p=0.000), gender (t=-4.246, p=0.000), marital status (t=-3.531, p=0.000), family type (F=5.742, p=0.00l), and occupation (t=3.356, p=0.001). 5) Perceived health status of the rural elderly was significantly correlated with demographic variables such as education (F=6.408, p=0.002), gender (t=2.949, p=0.003), marital status (t=0.802, p=0.034), family type (F=4.844, p=0.003), and occupation (t=-2.485, p=0.011). 6) Health problems of the rural elderly were significantly correlated with life style pattern variables such as drinking (F=5.223, p=0.006), smoking (F=4.087, p=0.007), salty food intake (F=3.424, p=0.034), greenish yellow vegetables intake (F=6.343, p=0.002) and fat food intake (F=5.327, p=0.005). 7) Perceived health status of the rural elderly was significantly correlated with life style pattern variables such as sleeping hours (F=3.966, p=0.020) and drinking (F=7.231. p=0.001). Conclusion: The findings of this study indicate that nurses need to understand health problems and perceived health status of the rural elderly and to develop health promotion programs for them in the future in the consideration of regional and environmental elements.

• 한방안이비인후피부과학회지
• /
• 제14권1호
• /
• pp.129-153
• /
• 2001

Background: SMG (升麻葛根湯加味方) is an herbal medicine which has been used in oriental medicine as a traditional therapeutic agent of pruritus and skin disease. Objective: This study was performed to investigate the effect of SMG on the anti-hypersensitivity and immune response in the murine of type I hypersensitivity induced by the experiment. Materials and Methods: Laboratory rats were primary sensitized with OA (ovalbumin); on day 1, rats of a Control group and Sample group (SMG group) were systemically immunized by subcutaneous injection of 1mg OA and 300mg of Al(OH)3 in a total volume of 2ml saline. The rats of the sample group were orally administered with an SMG water extract for 14 days after primary immunization. On day 14 after the systemic immunization, rats received local immunization by inhaling $0.9\%$ saline aerosol containing $2\%$(wt/vol) OA. A day after local immunization, BAL fluid and peripheral blood were collected from the rats. Total cell, lymphocyte, $CD4^+\;T\;cell,\;CD8^+\;T\;cell,\;CD4^+/CD8^+$ ratio in the BALF, and IgE, $CD4^+\;T\;cell,\;CD8^+$ T cell in the peripheral blood were measured and evaluated. Results: SMG showed a suppressive effect on the immune response in the rats. 1. Total Cells in the BALF decreased in the SMG treated group in comparison group, but statistic differences were not observed. 2. Total lymphocytes in the BALF were statistically decreased in SMG treated group in comparison to the control group. 3. CD4+ T cells in the BALF were statistically decreased in SMG treated group in comparison to the control group. 4. CD8+ T cells in the BALF were decreased in SMG treated group in comparison to the control group, but statistic differences were not observed. 5. The ratio of CD4+/CD8+ in the BALF was statistically decreased in SMG treated group in comparison to the control group. 6. The IgE level in serum was statistically decreased in SMG treated group in comparison to the control group. 7. The ratio of CD4+ and CD8+ in peripheral blood showed undetectable differences between each group of rats. From the experiment cited above, this study shows that SMG has both anti-hypersensitivity effects and immunoregulatory effects when administered to rats. Based on this experiment, it is suggested that SMG could be a useful immunomodulator and anti-allergy agent.

• 복식
• /
• 제52권8호
• /
• pp.29-39
• /
• 2002

It was increased leisure hours by automation and computerization of industry. Many people spend on hours in enjoying leisure sports, and then. nowadays, Many women tend to prefer casual wear to formal suits. The purpose of this research was to design of outdoor-wear that improve the functional and aesthetic effects for clothing comfort. Total 4 design prototype consisting of jumper and slacks were developed for this research. Outdoor-wear design forced on armhole type of jumper and ease of the back crotch length of slacks to improve the functional and aesthetic effects. And Outdoor-wear design focused on color harmony to aesthetic effects. Ease amount and materials of jumper and slacks were controlled. Design A: Jumper was designed as dropped shoulder with set-in steeve and band collar, A break-away zipper to facilitate ventilation control were made the area of back of jumper and the area of outside seam line of slacks Color of jumper and slacks were olive green color. Ease amount of the crotch length of slacks pattern was constructed as 7% of total crotch length: Design B 4DM cut pattern were applied to the jumper and slacks pattern. A break-away zipper to facilitate ventilation control were made the area of back of jumper and the area of inside seam line of thigh. Color of jumper and slacks were grey and orange color. Ease amount of the crotch length of slacks pattern was constructed as 5% of total crotch length. Design C : Jumper was designed as the set in sleeve and hood. and A break- away zipper to facilitate ventilation control were made the ares of the armhole and elbow. Color of jumper and slacks were ivory and orange color. Ease amount of the crotch length of slacks pattern was constructed as 5% of total crotch length. Design D : Jumper was designed as raglan sleeve. Color of jumper and slacks were olive green color. Ease amount of the crotch length of slacks pattern was constructed as 5% of total crotch length. Total six females, ages 20-45, served as subjects for this research. Subjects have standard body type, generally, wearing 66 size of ready-to-wear clothing. The performance of the newly designed outdoor-wear was evaluated for their effectiveness in several aspects such as conditions of skin temperature, sensory evaluation of comfort during body movements, appearance and color harmony and aesthetic collar design. Design 3 was appeared to be the most positive in aesthetic evaluation and functional effects of design 2 of 4DM cut pattern was appeared to be beter than other designs.

• Journal of Microbiology and Biotechnology
• /
• 제30권4호
• /
• pp.540-551
• /
• 2020

Sporotrichosis is a chronic and subacute mycosis causing epidemiological outbreaks involving sick cats and humans in southeastern Brazil. The systemic disease prevails in cats and in humans, with the symptoms restricted to the skin of immunocompetent individuals. Under these conditions, the prolonged treatment of animals and cases of recurrence justify the discovery of new treatments for sporotrichosis. This work addresses the antifungal activity of silver salts of Keggin-type heteropolyacid salts (Ag-HPA salts) such as Ag₃[PW₁₂O₄₀], Ag₆[SiW₁₀V₂O₄₀], Ag₄[SiW₁₂O₄₀] and Ag₃[PMo₁₂O₄₀] and interactions with the antifungal drugs itraconazole (ITC), terbinafine (TBF) and amphotericin B (AMB) on the yeast and mycelia forms of Sporothrix spp. Sporothrix spp. yeast cells were susceptible to Ag-HPA salts at minimum inhibitory concentration (MIC) values ranging from 8 to 128 ㎍/ml. Interactions between Ag₃[PW₁₂O₄₀] and Ag₃[PMo₁₂O₄₀] with itraconazole and amphotericin B resulted in higher antifungal activity with a reduction in growth and melanization. Treated cells showed changes in cell membrane integrity, vacuolization, cytoplasm disorder, and membrane detachment. Promising antifungal activity for treating sporotrichosis was observed for the Ag-HPA salts Ag₃[PMo₁₂O₄₀] and Ag₃[PW₁₂O₄₀], which have a low cost, high yield and activity at low concentrations. However, further evaluation of in vivo tests is still required.

• 대한화장품학회지
• /
• 제40권4호
• /
• pp.365-371
• /
• 2014

새로운 주름개선제 성분을 찾기 위해서 본 연구에서는 사람 피부 섬유아세포의 세포독성, 콜라겐 생합성, matrix metalloproteinase-I (MMP-1) 및 elastase 저해활성에 대한 Lactobacillus plantarum으로 발효된 오미자 발효액의 주름개선 효과를 평가하였다. 먼저, 오미자 추출물은 L. rhamnosus으로 $37^{\circ}C$에서 1일 동안 발효하였다. 발효물의 세포독성은 cytopathic effect reduction 방법에 의해 평가하였다. 콜라겐 생합성에 대한 발효물의 영향은 procollagen type-IC peptide EIA kit에 의해 평가하였으며, matrix metalloproteinase-I(MMP-1)에 대한 발효물의 영향은 Matrix Metalloproteinase-1 Biotrack activity Assay Kit에 의해 평가하였다. Elastase inhibition assay는 기질로써 N-Suc-$(Ala)_3$-nitroanilide을 사용하여 기질 반응에 의해 평가하였다. 결과로써 오미자 발효물은 사람 피부 섬유아 세포에 대해 $100{\mu}g/mL$의 농도에서 세포독성을 나타내지 않았다. 또한 오미자 발효물은 콜라겐 생합성을 촉진시켰으며, MMP-1의 저해 효과를 나타내었다(p < 0.05). Elastase inhibition assay에서 오미자 발효물의 $IC_{50}$은 $36.4{\mu}g/mL$이었다. 그러므로 본 연구에서 오미자 발효물은 주름개선 효과를 보유하고 있으며, 이것은 피부의 주름개선을 위해 사용가능하리라 사료된다.

• 대한화장품학회지
• /
• 제43권1호
• /
• pp.1-10
• /
• 2017

한의학에서 승마(Cimicifuge dahurica, C. dahurica), 황련(Coptis chinensis, C. chinensis), 황백(Phellodendri amurense, P. amurense) 추출물은 해독작용을 하며 후박(Magnol obovata, M. obovata) 추출물은 항균 효과가 있다고 알려져 있다. 본 연구에서는 승마, 황련, 황백, 후박 추출물을 혼합하여 기능성 화장품 소재로써의 이용 가능성을 검토하였다. MTT assay를 이용한 세포 독성평가와 DPPH와 ABTS를 이용한 항산화 효과를 측정한 결과, 단일 추출물보다 추출혼합물이 더 안전함을 확인 하였으며 농도 의존적으로 항산화 활성이 증가됨을 확인하였다. 뿐만 아니라 NO 생성을 억제함으로써 우수한 항염증 효과가 있을 것으로 예상되며, 섬유아세포에서 UVB로 유도된 세포 손상을 보호하면서 type 1 pro-collagen 합성량이 증가되는 것을 관찰하였다. 또한 추출 혼합물은 melanin 합성과 tyrosinase 활성 및 melanin 합성 관련 인자 및 효소들(MITF, tyrosinase, TRP-1, TRP-2)의 발현을 효과적으로 억제하였다. 이러한 연구결과로 보아 승마, 황련, 황백, 후박 추출 혼합물은 항노화 및 미백 등 기능성 화장품 소재로써 개발 가능성이 높을 것으로 사료된다.

• 대한기계학회논문집B
• /
• 제40권10호
• /
• pp.681-687
• /
• 2016

마이크로 인젝션을 바이오분야에 적용하기 위해 고압생성을 통해 침투하는 방법을 채택하였다. 그러나 고압의 액체를 인젝션 할 경우 그 양을 미세하게 하기 어렵다. 이러한 문제를 해결하기 위해는 고속으로 동작하는 개폐밸브에 의한 방법이 있다. 본 연구에서는 수백 Hz로 동작가능한 압전 액추에이터로 구성된 개폐밸브를 적용하여 실험하였다. 압전밸브를 구동하는 파형을 다양하게 조절하고 노즐의 구조에 의한 영향을 알아보기 위해 5가지 서로 다른 치수의 노즐을 제작하였다. 다양한 노즐과 구동파형 변수를 조절하면서 무엇이 인젝션 볼륨과 인젝션 힘에 큰 영향을 미치는지 확인하였다. 이 실험을 통해, 인젝션 볼륨을 줄이고 인젝션 힘을 증가시키는 방법을 알아냈고 목표치가 있다면 그에 맞는 다양한 값을 결정할 수 있게 되었다.

• 지질공학
• /
• 제10권1호
• /
• pp.51-62
• /
• 2000

경상계 퇴적암에서 산출되는 신촌 및 고란약수는 탄산을 다량으로 함유하는 탄산지하수이다. 탄산수의 화학적 유형은 Ca(Na)-$HCO_3$형에 속한다. 탄산수는 높은 $P_{CO2}$ 분압(0.29~1.01 atm)과 1,093~2,810$\mu$S/cm 범위의 높은 전기전도도를 보인다. 무기이온성분을 보면 Ca이 116~321mg/l 농도범위를 보이고 $HCO_3$성분이 702-2,115mg/l 농도로 가장 풍부한 성분이다. 그리고 Na 성분이 62~225mg/l 범위를, Mg 성분이 36.4~101mg/l 농도범위를, Fe는 1.0~31.5mg/l 농도범위를 보여 일반지하수에 비해 훨씬 높은 값을 보인다. 그 외 F, Li, Mn, Sr 등의 미량원소도 상당히 풍부한 편이다. 탄산수의 $^2H/^1H, ^{18}O/^{16}O$ 동위원소 분석결과 탄산수는 모두 순환수 기원이며, 삼중 수소의 수준으로 볼 때 1950년대 이후에 함양된 강수가 탄산수로 진화된 것으로 보인다. 약수내 $CO_2$의 공급은 퇴적암과 인접한 화강암 또는 산성 반암류의 심부에서 기원한 것으로 추정된다. 탄산수의 수질특성에 영향을 미친 근원광물은 퇴적암내 풍부한 탄산염광물과 앨바이트에 의한 것으로 해석되고, 열역학적 계산에 의한 포화지수를 볼 때 탄산수는 앨바이트에 대해서 용해성조건이며, 방해석과는 거의 평형상태를 이루고 있다.

• 대한관절경학회지
• /
• 제15권1호
• /
• pp.13-18
• /
• 2011

목 적: $TightRope^{(R)}$ (Arthrex, Inc, Naples, FL)를 이용한 급성 견봉쇄골 관절 탈구의 관절경적 오구쇄골 관절 고정술의 방사선학적 및 임상적 결과를 평가하고자 한다. 대상 및 방법: 2009년 2월부터 2010년 2월까지 Rockwood 3형 또는 5형의 급성 견봉쇄골 관절 탈구 환자 20명에 대해 $TightRope^{(R)}$를 이용하여 관절경적 오구쇄골 관절 고정술을 시행하였다. 추시 기간은 평균 13.4(10~22)개월이었다. 방사선학적 평가는 쇄골 관절 부하 사진을 통해 쇄골과 오구돌기 사이 거리를 건측과 비교하였고, 임상적 평가는 KSS(Korean Shoulder Scoring System)를 이용하였으며, 환자들의 미용적 만족도도 평가하였다. 결 과: 방사선학적 평가에서 18예는 매우 우수, 1예는 우수, 1예는 양호의 결과를 보였다. KSS는 평균 98.5(92~100)점이었으며, 전 예에서 만족할 만한 미용적 결과를 보였다. 1예에서 매듭에 의한 피부 압통 및 촉진되는 불편감을 호소하여 시행한 매듭 봉합술 후 국소 감염이 발생하여 국소 마취 하 배농술 및 2주간 항생제 사용으로 치유하였다. 결 론: Rockwood 3형 또는 5형의 급성 견봉쇄골관절 탈구의 치료에 있어 $TightRope^{(R)}$를 이용한 관절경적 오구쇄골 관절 고정술은 만족스러운 방사선학적 및 임상적 결과를 보이며, 술후 합병증이 거의 없고, 조기 재활이 가능하며, 뛰어난 미용적 결과를 보이고, 금속 고정물 제거를 위한 이차적 수술이 필요없는 훌륭한 치료 방법이 될 것으로 생각된다.