• 한국식품조리과학회지
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• 제31권3호
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• pp.378-386
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• 2015

We investigated the antioxidant, physicochemical, and sensory characteristics of dried type sodium reduced chicken bibimbap using dandelion complex extract powder of AF-343 (DCEP) as a home meal replacement. The DCEP is known to add moisture to the skin and to relieve the symptoms of atopic dermatitis. The sodium content of the standard sample was 1,190 mg per serving. The sodium was significantly reduced by 30%, resulting in 820 mg of sodium for the reduced-sodium group (p<0.05). The ash contents of the standard sample group with the DCEP showed significantly the highest value at 6.01% in all of the samples as affected by the minerals of the DCEP (p<0.05). Sensory characteristics of savory aroma, savory flavor, cooked vegetable flavor and hardness in all the samples did not show significant differences, implying that addition of DCEP and 30% sodium reduction did not have undesirable effects on those sensory attributes. Furthermore, chicken flavor, which was a bit oily in the standard samples tended to decrease slightly, leaving a desirable savory flavor increased in the reduced sodium groups. In acceptance tests, the samples did not show any significant differences, indicating that the DCEP added sodium-reduced samples may be potentially acceptable to consumers. Total flavonoid contents, ABTS and DPPH radical scavenging activity, indicators of biologically active ingredients such as antioxidant, anticancer, and antibacterial activities significantly increased with the amount of DCEP added (p<0.05).

• Archives of Plastic Surgery
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• 제41권5호
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• pp.493-499
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• 2014

Background Maintaining stability and restoring the aesthetic appearance are the fundamental goals when managing zygomatic fractures. We aimed to evaluate the stability and anthropometric outcomes of zygomatic fracture patients who underwent two-point fixation involving the infraorbital rim and zygomaticomaxillary buttress via the transconjunctival and gingivobuccal approaches without any skin incisions. Methods We examined 15 zygomatic fracture patients who underwent two-point fixation during a 3-year period. Stability was evaluated using three-dimensional facial bone computed tomography. Superoinferior and anteroposterior displacement of the zygoma was quantified. The aesthetic appearance of the periorbital region was evaluated using indirect anthropometry with standardized clinical photographs. The ratios between the eye fissure height and width, and lower iris coverage ratio were used to evaluate aesthetical changes. The bony displacement and aesthetic ratios were analyzed using Wilcoxon or Friedman tests. The correlation between the preoperative zygoma position and anthropometric values was analyzed. Results The positions of the zygoma were similar to those on the contralateral side at the long-term follow-up. The preoperative anthropometric measurements on the fractured side differed from those on the contralateral side, although these values were close to the normal values at the long-term follow-up. Furthermore, we noted that the anteroposterior displacement strongly positively correlated with the lower iris coverage rate (Spearman's coefficient=0.678, P=0.005). Conclusions Two-point fixation of zygomatic fractures achieved stable outcomes on long-term follow-up, and also appeared to be reliable in restoring the aesthetic appearance of the periorbital region.

• Toxicological Research
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• 제8권2호
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• pp.255-263
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• 1992

SKI 2053R and SKI 2053R-human serum albumin(HSA) mixture were examined for their antigenicity in Hartley guinea pigs as well as C57BL/6 mice in comparison with distilled water (DW), HSA and DW-HSA conjugate. Several antigenicity tests, including acitive systemic anaphylaxis(ASA), passive systemic anaphylaxis (PSA), passive cutaneous anaphylaxis (PCA) and indirect hamagglutination test (IHA), were performed according to the Established Regulations of National Institute of Safety Research. The results were as follows: 1. When guinea pigs were sensitized with SKI2053R or SKI2053R-HSA emulsified with complete Freund's adjuvant(CFA), these animals showed negative reactions in ASA and PSA. 2.No blue spot was observed on the back skin of guinea pigs in the PCA test. 3. Sera from guinea pigs revealed a negative reaction in IHA. 4.Guinea pigs were sensitized by HSA emulsified with CFA as a positive control, and these animals showed positive reactions in ASA, PSA, PCA, and IHA. As shown above, SKI2053R was considered to possess neither antigenic, nor haptenic properties, and confirmed not to have the haemagglutinating activity.

• Parasites, Hosts and Diseases
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• 제56권3호
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• pp.229-236
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• 2018

Cutaneous leishmaniasis (CL) has been one of the most common parasitic diseases in Saudi Arabia. This study exhibits the clinical features, diagnosis, cytokine profile and treatment of CL patients in Al-Taif province. Ninety CL suspects at a tertiary care general hospital were enrolled in one-year study. Patients were interviewed, clinically-examined, and subjected to laboratory tests: skin scraping smear microscopy, OligoC-TesT commercial PCR (Coris BioConcept) and kinetoplast DNA (kDNA) PCR for Leishmania diagnosis. Interferon-gamma (RayBio; Human $IFN-{\gamma}$ ) and nitric oxide (NO) levels in patients' sera were evaluated before treatment with sodium stibogluconate (pentostam) with 20-day intramuscular drug regimen. Positive rates of microscopy, commercial PCR and kDNA PCR were 74.4%, 95.5% and 100%, respectively. Patients came to hospital mostly in winter (45.0%). CL was frequently exhibited in Saudi patients (78.8%), male gender (70.7%), age <20 years (50.0%), rural-dwellers (75.5%) and patients with travel history (86.6%). Lesion was mostly single ulcer (93.3%), occurred in the face (67.7%). Upon pentostam treatment, 85.1% of ulcers showed rapid healing signs. Levels of $IFN-{\gamma}$ and NO were significantly higher in the healing than the non-healing cases (P<0.001). The kDNA PCR proved more sensitive than microscopy and OligoC-TesT commercial PCR. Our results open perspectives for $IFN-{\gamma}$ use as a biomarker predicting treatment response.

• Nutrition Research and Practice
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• 제7권6호
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• pp.488-494
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• 2013

A food allergy is an adverse health effect arising from a specific immune response that occurs reproducibly upon exposure to a given food. In those with food allergies that are thought to cause aggravation of eczema, food avoidance is important. The objective of this study was to research the nutritional status of patients with food allergies. A total of 225 subjects diagnosed with atopic dermatitis underwent a skin prick test as well as measurement of serum immunoglobulin E. Food challenge tests were conducted using seven food items: milk, eggs, wheat, soybeans, beef, pork, and chicken. At post-food challenge visits to the test clinic, participants completed a three-day dietary record, which included two week days and one weekend day, in order to evaluate energy intake and diet quality during the challenge. We analyzed nutrient intake based on differential food allergens. Subjects with a food allergy to milk showed lower intake of Ca, Zn, and vitamin B2, and subjects with a food allergy to egg showed lower intake of vitamin A, B1, B2, niacin, and cholesterol. Subjects with a food allergy to wheat and soybean showed lower intake of Ca, P, Fe, K, Zn, vitamin B2, vitamin B6, and niacin; and subjects with a food allergy to beef, pork, and chicken showed lower intake of Fe and higher intake of K, vitamin A, B2. Subjects with atopic dermatitis were lacking in several nutrients, including vitamin A and vitamin C. A greater number of food allergies showed an association with a greater number of nutrient intake deficiencies. Allergen avoidance is the basic treatment for atopic dermatitis. However, when the allergen is food, excessive restriction can lead to nutrition deficiency. Findings of this study suggest the necessity for enhanced nutritional education in order to provide substitute foods for patients with food allergies who practice food restriction.

• 한국지반환경공학회 논문집
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• 제14권3호
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• pp.19-27
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• 2013

최근, 갑작스런 집중호우로 인하여 자연 및 인공사면의 붕괴가 종종 발생하고 있다. 이를 예방하기 위한 여러 가지 보강공 법들이 개발되어 적용되고 있다. 그 중에서도 쏘일네일링 공법은 시공성과 경제성 등의 이유로 그 활용이 증대되고 있다. 쏘일네일링 공법은 다른 보강공법들과 함께 사용하는 경우도 있으며, 또한 강재와 시멘트그라우팅과의 일종의 복합 구조체로서 지반과 그라우팅사이의 마찰력을 활용하는 공법이다. 본 연구에서는 선단확장형 쏘일네일링 공법을 개발하였으며, 이는 네일 끝단에 앵커체가 부착되어 있다. 이 앵커체는 네일링 작업 중 네일 끝단에서 확개되면서 지반에 정착되게 된다. 본 연구에서는 네일링 시공 후 그라우팅을 하지 않은 상태와 그라우팅 후 양생이 된 경우 각각에 대해 현장인발저항시험을 실시하였다. 시험결과로부터 선단확장형 쏘일네일의 선단쐐기력을 분석하였으며, 거동특성을 종합적으로 고찰하였다.

• 대한화장품학회지
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• 제36권3호
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• pp.221-226
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• 2010

10년 이상 자연 발효된 콩 발효 식품에서 희귀 이소플라본 성분인 7, 8, 4'-trihydroxyisoflavone을 분리하였고, 분리된 성분의 항산화 효과를 비효소적인 방법으로는 DPPH 법을, 효소적인 방법으로는 xanthine oxidase법을 이용하여 확인하였다. 그 결과 7, 8, 4'-trihydroxyisoflavone는 농도 의존적으로 비타민 C와 유사한 DPPH 라디칼 소거 효능을 가지고 있음을 보여주었고 $6.6{\pm}0.4\;{\mu}M$ 농도에서 xanthine oxidase에서 생성된 superoxide 라디칼을 50 % 수준까지 낮춤을 보여주었다. 또한, 이 희귀 이소플라본 성분은 UVB로 유도된 MMP-1의 생성을 초기 수준으로 억제하는 것으로 나타나 피부 노화 억제에 유용한 성분임을 확인할 수 있었다.

• 태양에너지
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• 제10권2호
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• pp.10-17
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• 1990

건물의 사양으로부터 시뮬레이션에 의해 열성능을 추출하는 기법과 실측 데이타로 부터 연역적인 방법에 의해 열성능을 추출하는 기법을 연합시켜 단기간의 측정에 의해 건물의 열성능을 간단하고 정확하게 결정할 수 있는 기법을 Test cell에 적용하였다. 실험과정 및 자료분석은 PSTAR 기법에 따라 수행했다. 각 측정기간은 3일간으로 비거주 상태에서 측정했으며, 실내온도, 외기온, 일사량, 공급열량, 풍속, 상대습도등의 자료를 측정하여 건물의 사양에 의한 시뮬레이션 모델의 재표준화에 사용했다. 아래의 3개 주요계수들이 본 분석에 의해 얻어졌다. 1) 건물 열손실계수 : BLC(표면전도율+침기에 의한 전도율); 2) 유효 건물열용량; 3) 유효 태양열 획득량. 그리고 재표준화된 식으로부터 예측된 값과 건물의 사양으로 시뮬레이션에 의해 예측된 값과 측정된 값과의 비교를 통해 재표준화된 식이 실제건물의 열성능을 잘 묘사함을 알 수 있었다. 장기간의 외삽으로 기후 자료를 이용하여 표준 쾌적도를 유지하기 위해 필요한 에너지를 계산했다.

• 한국지반공학회지:지반
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• 제14권1호
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• pp.71-80
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• 1998

서해안에 위치한 서산지역에서 연구용 prestressed concrete 말뚝을 3본을 설치하고 주변에서 콘관입시험을 수행하여 말뚝의 주면마찰력을 추정하는 연구를 수행했다. 본 연구에서 이용한 말뚝 지지력 산정식은 세계적으로 많이 이용하고 있는 Schmertmann방법, Tumay & Fakroo방법 및 프랑스의 LCPC방법을 이용하였다. 콘관입시험의 측정결과를 이용하여 3가지 방법으로 예측한 말뚝 의 주면마찰력과 현장에서 수행한 정역학적 재하시험 및 동재하시험에서 산정된 주면마찰력과의 비교하여 3가지 예측방법들에 대한 신뢰성을 평가했다. CPT를 이용한 3가지 예측식으로 산정한 말뚝의 주면마찰력은 전체적으로 25일과 42일이 지난후 수행한 정재하시험에 의한 주면마찰력을 상당히 과소평가했으나, 항타시좌 말뚝설치후 2주가 지난 시점에 수행한 동재하시험결과와는 유사한 말뚝의 주면마찰력을 예측했다.

• Korean Chemical Engineering Research
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• 제51권5호
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• pp.536-539
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• 2013

본 연구에서는 황벽나무, 두충나무 등을 포함하는 복합수목추출물의 항균활성 효과 및 안전성에 대해 검토하였다. 항균활성은 피부상재균이며 기회 병원성균인 Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli 및 Candida albicans에 대해 disc 확산법으로 실험되었다. 안전성 시험으로는 단회 경구투여 독성시험, 단회투여 흡입독성 시험, 반복투여 흡입독성시험이 실시되었다. 항균력효과시험 결과 추출물은 Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans에 대해 우수한 항균활성을 보여주었으나, Escherichia coli에서는 항균활성이 없었다. 복합수목추출물의 단회 경구투여 독성시험, 단회투여 흡입독성시험 및 반복투여 흡입독성시험의 결과 독성은 관찰되지 않았다. 따라서 황벽나무, 두충나무 등을 포함한 복합수목추출물은 천연 항살균제로서 상업화 가능성이 매우 높음을 알 수 있었다.