• Title/Summary/Keyword: Skin/pathology

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Effects of Various Proteins in the Diet on Fatty Acid Concentration in the Skin, Cutaneous Histology, Clinicopathology, and Thyroid Function in Dog (개에서의 피부, 피부조직학, 임상병리학 및 갑상선 기능에 있어서 지방산 농도에 관한 규정식 중 다양한 단백질들의 제반 영향(6))

  • White Stephen D.;Rosychuk Rod A.W.;Scott Kathryn V.;Carey Daniel P.;Longardner Curtis;Schultheiss Patricia C.;Salman Mowafak
    • Journal of the korean veterinary medical association
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    • v.33 no.1
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    • pp.22-28
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    • 1997
  • 12마리의 개들을 12주동안 6종류의 규정식으로 각각 급여시켰다. 규정식들은 단지 단백질원 즉 닭고기, 새끼양의 고기, 물고기, 쇠고기 및 콩이란 것에서만 차이가 있었다. 개들은 CBC 즉, 혈청화학프로필, 요분석, TSH반응시험 및 피부생검을 통하여 평가하였다. 피부생검은 조직학적으로 하는 것과 피부지방산 농도의 측정을 통한 평가, 두가지 방법으로 평가하였다. 평가된 지방산들은 리롤레산, 감마-리롤렌산, 알파-리롤렌산, 아라키돈산, 아이코사테트라에노이산 및 아이코사펜타에노이산 등이었다. 개들은 주관적으로 생검채취부위에서 털의 재성장과 비늘(피부의 얇은 조각)의 존재유무로 평가하였다. 결과에서 보면 각종의 규정식을 급여시킨 개들 사이에서 CBS, 조직적 소견 또는 피부지방산 수치에서 차이가 나타나지 않았다. 쇠고기 규정식을 급여시킨 12마리중 3마리의 개에서 고콜레스테롤 혈증이 있었고, 콩 규정식을 급여시킨 12마리중 9마리의 개에서 알카리성 오줌과 돼지고기를 급여시킨 12마리중 4마리가 비늘이 주관적 증가가 있었고, 털의 재성장이 감소된 것으로 나타났다.

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Studies on disease of catfish(Silurus asotus) in Korea Pathology of skin ulcerous by A. hydrophila (한국산메기(Silurus asotus)의 질병에 관한 연구)

  • 한규삼;최인열;배정준;김영길;이근광;김영진
    • Korean Journal of Veterinary Service
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    • v.16 no.2
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    • pp.103-110
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    • 1993
  • The Aeromonas strains were isolated from diseased cultured catfsh (Silurus asotus) in the ponds near by Gochang of Chunbuk. The present isolates were identified as A. hydrophila based on their biological and biochemica1 characteristics. The isolates of A. hydrophila were named GC-1, GC-2, GC-3, GC-4 and GC-5, Five strains were grew optimally at temperatures $35^{\circ}C,$ pH 7.5 and in 0.5 to l% NaCl. This bacterium(GC-1) was injected into health catfish in order to prove the causative agent of ascites and haemorrhagic ulcers. The symptoms in cat fish infected by this challenge method were observed to be very similar to the symptoms of a natural infection, but controls did not show any abnormal symptoms during the experimental period. At 24 post-injection, the red spot developed around the injection site and the haemorrhagic ulcers was extended near the gill and ventral fin. Five strains were tested for drug sensitivity by plate method. All strains were sensitivity to gentamicin and resistant to penicillin, streptomycin and tetracycline.

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Melanoma in Iran: a Retrospective 10-Year Study

  • Ferdosi, Samira;Saffari, Mojtaba;Eskandarieh, Sharareh;Alishahi, Raziyeh;Moghaddam, Mahsa Ghaffari;Ghanadan, Alireza;Shirkoohi, Reza
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2751-2755
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    • 2016
  • Background: Melanoma, the most life-threatening type of skin cancer, is a malignant tumor initiating in melanocytes that rapidly metastasizes and causes death. Materials and Methods: In this retrospective study, samples were selected from patients' information files in our Cancer Institute in Tehran with a designed checklist. A total of 322 files were found from 2003 until 2012. Then the raw data were transferred to Statistical Package for Social Sciences (SPSS) software version 16 and additional analysis was performed by Students t-test. The important variables were considered according to the available information from history of pathology including age, gender, occupation, stage and location of tumor. Results: Our data showed that incidence of melanoma has been different in the studied 10-year period according to age. Also, incidence of melanoma was higher in men than women. It was more common in lower limbs. More commonly housewives among women and farmers among men were affected by melanoma. Conclusions: Taken together the descriptive data clarified general aspects of this disease for further screening and interventions.

Multifocal intraosseous calvarial hemangioma misdiagnosed as subgaleal lipoma

  • Kim, Joo-Hak;Ahn, Chang Hwan;Kim, Kyung-Hee;Oh, Sang-Ha
    • Archives of Craniofacial Surgery
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    • v.20 no.3
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    • pp.181-185
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    • 2019
  • Intraosseous hemangioma is a rare, slow-growing, benign tumor of blood vessels. Primary hemangioma of the skull is a benign lesion that may appear as a palpable mass or accidentally detected during image evaluation. Simple radiography is the most commonly used technique to localize a lesion and computed tomography (CT) may help determine the effect of a lesion. We report a case of multifocal intraosseous calvarial hemangioma developed in the subgaleal plane of an elderly male patient. Ultrasonography examination revealed hyperechoic striated septae parallel to the skin and discontinuity of the focal cortex, however, the underlying bone cortex appeared relatively intact. No significant flow is observed on Doppler ultrasonography. Based on these evaluations, the mass was interpreted by a radiologist as a subgaleal lipoma. This case highlights the importance of additional CT examination in a patient presenting with a scalloping sign of the underlying calvarium. Clinicians also should be aware of the possibility of intraosseous calvarial hemangiomas in lesion. Furthermore, the proper choice of congenital vascular malformation term is still quite confusing with misconception present in the literature.

Two separate nodules of Merkel cell carcinoma occurring concomitantly on one cheek

  • Hwang, Woosuk;Kang, Mi Seon;Kim, Jin Woo
    • Archives of Craniofacial Surgery
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    • v.20 no.3
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    • pp.203-206
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    • 2019
  • Merkel cell carcinoma (MCC) is a rare and highly aggressive neuroectodermal carcinoma arising from mechanoreceptor Merkel cells. Multiple MCCs are even rarer. We report a case of two independent MCCs simultaneously present in the cheek of a patient, which were effectively and esthetically treated using a cheek flap. Punch biopsy performed in a 60-year-old woman admitted with a chief complaint of two skin-colored hard nodules in her left cheek, accompanied by an itching sensation, was suggestive of MCC. Accordingly, we performed sentinel lymph node biopsy through the modified Blair incision under general anesthesia, in cooperation with the head and neck surgery department. The defect was covered with a cheek flap by slightly extending the existing incision following wide excision with a safety margin of 1 cm. This paper is significant in that it introduces an effective reconstruction technique that maintains function using a cheek flap for the management of this rare case. In addition, this paper is the first to classify multiple MCCs according to the time of onset. We believe that this paper presents an effective alternative reconstruction technique with sentinel node biopsy through the modified Blair incision.

Treatment of primary cutaneous anaplastic large cell lymphoma

  • Baik, Bong Soo;Lee, Wu Seop;Ji, So Young;Park, Ki Sung;Yang, Wan Suk;Kim, Sun Young
    • Archives of Craniofacial Surgery
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    • v.20 no.3
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    • pp.207-211
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    • 2019
  • Primary cutaneous anaplastic large cell lymphoma (C-ALCL) is a rare subtype of primary cutaneous lymphoma with a favorable prognosis. Primary cutaneous CD30+ lymphoproliferative disorders, which include C-ALCL and lymphomatoid papulosis, are the second most common group of cutaneous T-cell lymphomas. C-ALCL is comprised of large cells with anaplastic, pleomorphic, or immunoblastic cytomorphology, and indeed, more than 75% of the tumor cells express the CD30 antigen. C-ALCL clinically presents with solitary or localized reddish-brown nodules or tumors, and sometimes indurated papules, and they may be with ulceration covering with dark eschar. Multifocal lesions are seen in 20% of the patients. Extracutaneous dissemination, which mainly involves the regional lymph nodes, occurs in 10% of patients. A 69-year-old man noticed a mild elevated cutaneous lesion containing central ulceration covering with brownish black necrotic tissue on the right lower lip, and the lesion was surgically removed. After the first operation, another skin lesion was developed and the histological examination confirmed the diagnosis, C-ALCL. Eight specimens were excised during the 7-month follow-up period. The patient started the treatment with low-dose oral methotrexate (15 mg/wk) and there was no recurrence for 11 months.

Primary hepatic sarcoidosis presenting with cholestatic liver disease and mimicking primary biliary cholangitis: a case report

  • Park, Young Joo;Woo, Hyun Young;Kim, Moon Bum;Ahn, Jihyun;Heo, Jeong
    • Journal of Yeungnam Medical Science
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    • v.39 no.3
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    • pp.256-261
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    • 2022
  • Sarcoidosis often involves the liver. However, primary hepatic sarcoidosis confined to the liver without evidence of systemic involvement is rare. We report the case of a 37-year-old man with hepatic sarcoidosis who initially presented with elevated liver enzymes and suspicious cirrhotic nodules on computed tomography. The patient had cirrhosis but did not have portal hypertension. Based on the initial histopathologic finding of chronic granulomatous inflammation and the common clinical characteristics of sarcoidosis, he was initially diagnosed with primary biliary cholangitis, and his daily dosage of ursodeoxycholic acid was increased to 900 mg. After 14 months of treatment, his total serum bilirubin concentration was 10.9 mg/dL (upper normal limit, 1.2 mg/dL). Additionally, a transjugular liver biopsy revealed multiple noncaseating granulomas. He was diagnosed with primary hepatic sarcoidosis involving the lungs, heart, spleen, kidneys, and skin. Treatment with methylprednisolone was initiated. Two weeks later, he was started on azathioprine, and the dose of steroid was simultaneously reduced. These findings indicate the importance of including hepatic sarcoidosis as a possible diagnosis in patients with elevated liver enzymes or cryptogenic cirrhosis.

Occurrence of Kiwifruit Vine Decline Syndrome and Its Prevention Using Rootstock Tolerant to Waterlogging (키위 쇠락증상 발생 및 습해 저항성 대목을 이용한 예방)

  • Gyoung Hee Kim;Eu Ddeum Choi
    • Research in Plant Disease
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    • v.29 no.4
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    • pp.425-432
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    • 2023
  • Kiwifruit industry has been threatened by the emergence of kiwifruit vine decline syndrome causing plant death within one or two years from symptom appearance. The main symptoms of this syndrome are root cortex breakdown, leaf necrosis, phylloptosis, fruit skin wrinkling, and twig wilting. Kiwifruit vine decline syndrome occurred on both Actinidia chinensis var. chinensis and A. chinensis var. deliciosa in mid-summer after rainy season. Kiwifruit vine decline syndrome was turned out to be severely occurred in wettable clay soils affected by waterlogging or poor aeration. No pathogens were directly correlated with the syndrome. Kiwifruit vine decline syndrome could be expected to be efficiently prevented controlled using Bounty 71 rootstock tolerant to water stress such as waterlogging.

Imaging Findings of a Malignant Rhabdoid Tumor in the Stomach: A Case Report (위에 발생한 악성 횡문근양 종양의 영상 소견: 증례 보고)

  • Hye Ran Yoon;Dong Hee Park;Joonseog Kong
    • Journal of the Korean Society of Radiology
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    • v.82 no.2
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    • pp.493-497
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    • 2021
  • A malignant rhabdoid tumor is an aggressive tumor that occurs mainly in the kidney of infants and children. When it occurs in extrarenal sites, it is referred to as an extrarenal malignant rhabdoid tumor. Although a few cases of malignant rhabdoid tumor occuring in the central nervous system, liver, brain, skin, and soft tissue have been reported, it is rarely observed in the stomach. We report the imaging findings of a malignant rhabdoid tumor of the stomach that mimicked a gastric lymphoma in a patient who presented with melena.

Subungal Mixed Tumor Mimicking Glomus Tumor: A Case Report and Literature Review (사구체 종양으로 오인된 손톱 밑 종양: 증례 보고와 문헌 고찰)

  • Jaemin Kim;Hyeongju Kwon;Jinrok Oh;Hyunjung Kim
    • Journal of the Korean Society of Radiology
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    • v.83 no.5
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    • pp.1134-1140
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    • 2022
  • Mixed tumors are well-circumscribed lesions exhibiting epithelial and/or myoepithelial cells and they usually occur in the skin and salivary glands. Soft tissue mixed tumors are extremely rare. Therefore, radiographic findings of soft tissue mixed tumors have very rarely been described in the radiologic literature. Here, we report a rare case of subungual mixed tumor in a 65-year-old female who presented with left 2nd finger pain, describe the radiographic findings, and discuss the differential diagnosis of the tumor.